Pioglitazone: all 341 studies that test it

Page 1 of 4. Open to participants first (28), then studies with results posted, then the rest; newest registration first within each.

• Rezdiffra® With Concomitant Therapies Commonly Used to Treat Comorbidities in Adults With MASH and F2-F3 FibrosisRecruitingNCT07848191Phase 4
• Effect Clomiphene vs Clomiphene Along With Pioglitazone on Ovarian Stimulation RateRecruitingNCT07462065Phase 4
• Empagliflozin Versus Statins in Non-Alcoholic Fatty Liver DiseaseNot yet recruitingNCT07180745Phase 4
• An Open-Label, Bayesian Adaptive Phase II Clinical Study in HR+/HER2- Advanced Breast Cancer After Progression on Standard TherapyRecruitingNCT07117630Phase 2
• A Study to Evaluate the Pharmacokinetics and Safety Between "BR3006" and Co-administration of "BR3006A", "BR3006B", and "BR3006C" in Healthy Adult Volunteers (Fed)RecruitingNCT07083401Phase 1
• A Study to Evaluate the Pharmacokinetics and Safety Between "BR3006" and Co-administration of "BR3006A", "BR3006B", and "BR3006C" in Healthy Adult Volunteers (Fasting)RecruitingNCT07083388Phase 1
• SGLT2i, Pioglitazone, and Ketone Production in T1DRecruitingNCT07056699Phase 3
• Pioglitazone and Empagliflozin for Fatty Liver Disease in Type 2 DiabetesRecruitingNCT06989723Phase 4
• Can the Addition of Pioglitazone to SGLT2 Inhibitor in Type 1 Diabetic Patients Amplify the Decrease in HbA1c and Prevent the Increase in Plasma Ketone Concentration?Not yet recruitingNCT06922656Phase 4
• Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis/Acute Pancreatitis Associated Diabetes MellitusRecruitingNCT06729996Phase 2
• Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or TirzepatideRecruitingNCT06657209Phase 4
• Early Application of Memantine and Pioglitazone to Protect Cognitive Function After RadiotherapyNot yet recruitingNCT06594172Phase 2
• Prevention of Progression of Prediabetes, Obesity and CV RiskRecruitingNCT06446531Phase 1
• Bioenergetic Effect of Pioglitazone in CLD-PHRecruitingNCT06336798Phase 2
• Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset DiabetesRecruitingNCT06246799Phase 3
• A Trial to Evaluate the Efficacy of Pioglitazone to Promote Renal Tolerance in ANCA-associated Vasculitis - RENATO TrialRecruitingNCT05946564Phase 3
• Efficacy of Empagliflozin and Pioglitazone in Diabetic Patients With NAFLDNot yet recruitingNCT05942963Phase 4
• Effects of Pioglitazone in Calcific Aortic Valve DiseaseNot yet recruitingNCT05875675Phase 2
• Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus ParticipantsRecruitingNCT05838287Phase 4
• The Role of Pioglitazone in Vascular Transcriptional RemodelingRecruitingNCT05775380Phase 4
• A Pilot Study of Monitoring Insulin Levels and Treating Hyperinsulinemia and Hyperglycemia With Pioglitazone in Patients Treated With Alpelisib for Metastatic Breast Cancer.RecruitingNCT05753657Early Phase 1
• A Clinical Trial to Evaluate the Efficacy, Tolerability, and Safety of a Fixed Dose Combination of Spironolactone, Pioglitazone & Metformin (SPIOMET) in Polycystic Ovary Syndrome (PCOS)RecruitingNCT05394142Phase 2
• Quantifying Hepatic Mitochondrial Fluxes in HumansRecruitingNCT05305287Phase 4
• Pioglitazone Therapy Targeting Fatigue in Breast CancerRecruitingNCT05013255Phase 2
• Low-Dose Pioglitazone in Patients With NASH (AIM 2)RecruitingNCT04501406Phase 2
• Insulin Regulation of Lipolysis and Lipolysis ProteinsRecruitingNCT03866408Early Phase 1
• Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)RecruitingNCT03109288Phase 1/2
• Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)RecruitingNCT02969798Not applicable
• Effects of Pioglitazone on Exogenous Carbohydrate Oxidation During Steady-State Exercise at High AltitudeCompletedNCT06164665Phase 4Results posted
• Safety and Suitability of Supplementing Early MIP Surgery (MIPS) of ICH With PioglitazoneTerminatedNCT05582707Phase 2Results posted
• Effects of Pioglitazone on Stress Reactivity and Alcohol CravingCompletedNCT05107765Phase 1/2Results posted
• Pathogenesis of Uric Acid Nephrolithiasis: Role of Pioglitazone/Weight LossCompletedNCT04370093Phase 4Results posted
• Pioglitazone for Idiopathic GastroparesisCompletedNCT04300127Early Phase 1Results posted
• Pioglitazone Treatment for Hyperglycemic Acute Ischemic StrokeTerminatedNCT04123067Phase 1/2Results posted
• Effects of Pioglitazone on Stress Reactivity and Alcohol Craving (Pilot)TerminatedNCT03860753Phase 1/2Results posted
• A Study to Determine the Bioequivalence of Alogliptin and Pioglitazone When Administered as Individual Tablets and as Fixed-Dose Combination (FDC)-SYR-322-4833 BL Tablets to Healthy Russian ParticipantsCompletedNCT03501277Phase 1Results posted
• Pioglitazone to Reduce Sympathetic Overactivity in CKD PatientsTerminatedNCT03471117Phase 4Results posted
• Effect of Pioglitazone on Insulin Resistance, Atherosclerosis Progression and Clinical Course of Coronary Heart DiseaseCompletedNCT03011775Phase 4Results posted
• PPARγ Agonist Treatment for Cocaine DependenceCompletedNCT02774343Phase 1/2Results posted
• Pioglitazone and Tyrosine Kinase Inhibitor in Treating Patients With Relapsed Chronic Myeloid LeukemiaTerminatedNCT02730195Phase 2Results posted
• Use of Low Dose Pioglitazone to Treat Autosomal Dominant Polycystic Kidney DiseaseCompletedNCT02697617Phase 2Results posted
• Fatty Liver Study in Patients With Type II DiabetesTerminatedNCT02365233Phase 4Results posted
• Preventing Squamous Cell Skin CancerCompletedNCT02347813Phase 2Results posted
• Role of PPAR-y Agonists in Immunomodulation and Vascular Prevention in SLE (PPAR-SLE)CompletedNCT02338999Phase 1/2Results posted
• AD-4833/TOMM40_303 Extension Study of the Safety and Efficacy of Pioglitazone to Slow Cognitive Decline in Participants With Mild Cognitive Impairment Due to Alzheimer DiseaseTerminatedNCT02284906Phase 3Results posted
• Nutrition, Inflammation and Insulin Resistance in End Stage Renal Disease-Aim 2CompletedNCT02278562Phase 2Results posted
• Obesity, Sleep Apnea, and Insulin ResistanceCompletedNCT02192684Not applicableResults posted
• Effectiveness and Safety of Adding Compound Preparation of Pioglitazone and Metformin for Type 2 Diabetic PatientsCompletedNCT02099838Phase 4Results posted
• Efficacy of Pioglitazone in Participants With Inadequately Controlled Type 2 Diabetes Mellitus Treated With Stable Triple Oral TherapyCompletedNCT01972724Phase 4Results posted
• Biomarker Qualification for Risk of Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease (AD) and Safety and Efficacy Evaluation of Pioglitazone in Delaying Its OnsetTerminatedNCT01931566Phase 3Results posted
• A Phase II Study of Pioglitazone for Patients With Cancer of the PancreasCompletedNCT01838317Phase 2Results posted
• Cellular Dynamics of Subcutaneous Fat Distribution in Obese WomenCompletedNCT01748994Not applicableResults posted
• Pioglitazone for the Treatment of Bipolar DepressionTerminatedNCT01717040Phase 4Results posted
• Safety and Efficacy of Roflumilast and Pioglitazone in Treating Adults With Nonalcoholic SteatoHepatitisTerminatedNCT01703260Phase 2Results posted
• Pioglitazone in Thyroid CancersCompletedNCT01655719Phase 2Results posted
• Role of Proinflammatory Signaling in Alcohol CravingTerminatedNCT01631630Phase 2Results posted
• Metabolic Abnormalities in HIV-infected PersonsCompletedNCT01612858Phase 4Results posted
• Efficacy Study of Pioglitazone and Metformin and Association Between Pioglitazone Response and Peroxisome Proliferator-activated Receptor Gamma Gene Variants in Bangladeshi Type 2 Diabetes Mellitus SubjectsCompletedNCT01589445Phase 4Results posted
• Myocardial Dysfunction in Type 2 Diabetes Mellitus (T2DM)CompletedNCT01588470Phase 4Results posted
• Pioglitazone in Patients With Mood DisordersCompletedNCT01559857Phase 4Results posted
• Study of Changes in Hepatic Fat Following Administration of MK-4074 and Pioglitazone Hydrochloride (MK-4074-008)CompletedNCT01431521Phase 1Results posted
• Pioglitazone for Heroin and for Nicotine DependenceTerminatedNCT01395797Phase 1/2Results posted
• Effects of Pioglitazone, a PPARgamma Receptor Agonist, on the Abuse Liability of OxycodoneCompletedNCT01395784Phase 2Results posted
• Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic ShockCompletedNCT01352182Phase 1/2Results posted
• Pioglitazone Hydrochloride in Treating Patients With Stage IA-IIIA Non-small Cell Lung CancerTerminatedNCT01342770Phase 2Results posted
• Long-term Safety Study of Alogliptin Used in Combination With Thiazolidine in Participants With Type 2 Diabetes in JapanCompletedNCT01318122Phase 2/3Results posted
• Efficacy and Safety of Alogliptin Used Combination With Thiazolidine in Participants With Type 2 Diabetes in JapanCompletedNCT01318070Phase 2/3Results posted
• Effect of Adipokines in Hemodialysis PatientsCompletedNCT01301027Not applicableResults posted
• Insulin Resistance in Non-alcoholic Fatty Liver DiseaseTerminatedNCT01289639Not applicableResults posted
• Efficacy and Safety of Alogliptin in Participants With Type 2 DiabetesCompletedNCT01289119Phase 3Results posted
• Pioglitazone in Early Parkinson's DiseaseCompletedNCT01280123Phase 2Results posted
• Bioequivalence of a Fixed Dose Combination Tablet Linagliptin/Pioglitazone Compared With Its Mono-componentsCompletedNCT01276327Phase 1Results posted
• Effect of Pioglitazone on TIMP-3 and TACE in Type 2 DiabetesCompletedNCT01223196Phase 4Results posted
• Adding Sitagliptin or Pioglitazone to Type 2 Diabetes Mellitus Insufficiently Controlled With Metformin and SulfonylureaCompletedNCT01195090Phase 4Results posted
• Clinical Trial of Pioglitazone for Prevention of Cardiac Allograft Vasculopathy After Heart TransplantationCompletedNCT01186250Phase 2Results posted
• 30 Week Parallel Group Comparison Study of Linagliptin + Pioglitazone (5+15, 5+30 and 5+45 mg) qd Versus Respective Monotherapies, Followed by a Comparison of 5mg+30mg and 5mg+45mg Versus Respective Monotherapies in Type 2 Diabetes for up to 54 WeeksCompletedNCT01183013Phase 3Results posted
• Effects of Pioglitazone on High-density Lipoprotein (HDL) Function in Persons With DiabetesCompletedNCT01156597Phase 3Results posted
• Effect of Different Interventions on Glycemic Control and β-cell Function in Newly Diagnosed Type 2 Diabetic PatientsCompletedNCT01147627Not applicableResults posted
• Pharmacogenomics of ThiazolidinedionesCompletedNCT01135394Not applicableResults posted
• Does Pioglitazone Increase the Production of 15-EPI-Lipoxin A4?CompletedNCT01040819Phase 4Results posted
• HIV Acquired Lipodystrophy (HAL) Classification, Measurement and Fat Response to Thiazolidinedione (TZD) (Pioglitazone)CompletedNCT01023620Not applicableResults posted
• DPP-4 Inhibition and TZD for DM PreventionTerminatedNCT01006018Not applicableResults posted
• Prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) in Hispanics With Diabetes Mellitus Type 2 (T2DM) and Role of TreatmentCompletedNCT01002547Phase 4Results posted
• A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory AsthmaCompletedNCT00994175Phase 2Results posted
• Pioglitazone for Oral Premalignant LesionsTerminatedNCT00951379Phase 2Results posted
• Effect of Thiazolidinediones on Human BoneCompletedNCT00927355Not applicableResults posted
• Pioglitazone to Treat Adults Undergoing Surgery for Non-small Cell Lung CancerTerminatedNCT00923949Phase 2Results posted
• Thiazolidinedione Intervention With Vitamin D EvaluationTerminatedNCT00879970Phase 4Results posted
• Effects of Pioglitazone on Insulin and Glucose Metabolism in Women With Polycystic Ovary Syndrome (PCOS)TerminatedNCT00868140Not applicableResults posted
• Effects of Pioglitazone on Platelet FunctionCompletedNCT00861341Phase 2Results posted
• Pioglitazone on Pancreatic Steatosis and Bone HealthCompletedNCT00855010Not applicableResults posted
• Effect of Pioglitazone and Exenatide on Body Weight and Beta Cell FunctionCompletedNCT00845182Phase 4Results posted
• Ghrelin Regulation and Structure: Effect of Thiazolidinedione Therapy on GhrelinTerminatedNCT00843791Not applicableResults posted
• Pioglitazone for the Treatment of Bipolar Disorder and Comorbid Metabolic Syndrome or Insulin ResistanceCompletedNCT00835120Phase 4Results posted
• Insulin Resistance in Pulmonary Arterial HypertensionTerminatedNCT00825266Phase 2Results posted
• Pilot Study of Pioglitazone for the Treatment of Moderate to Severe Asthma in Obese Asthmatics (Glitz Asthma)TerminatedNCT00787644Phase 2Results posted
• Chronic Pancreatitis. Effect of Pioglitazone on Endocrine Function, Exocrine Function & Structure, Pain & Life QualityCompletedNCT00782795Phase 2Results posted
• Efficacy of Pioglitazone/Metformin Combination Therapy in Subjects With Type 2 Diabetes Mellitus and Dyslipidemia.CompletedNCT00770653Phase 3Results posted
• Inflammation and Insulin Resistance in Rheumatoid ArthritisCompletedNCT00763139Not applicableResults posted
• Pioglitazone to Treat Fatty Liver in Patients With HIV and Hepatitis C InfectionsTerminatedNCT00742326Phase 4Results posted

← Pioglitazone overview