Fatty Liver clinical trials
The registry lists 662 studies for Fatty Liver across more than 10 countries. 184 are recruiting or about to start. 251 of them are mainly about Fatty Liver (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Non-alcoholic Fatty Liver Disease too: 2,015 studies, 453 open.
ClinicalTrials.gov finds 2,251 studies for Fatty Liver. How that becomes 661 here
This page counts the studies the registry files under Fatty Liver, and those it files under no condition that list Fatty Liverthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 2,251Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −1,352Filed under a narrower condition, counted on its own pageNon-alcoholic Fatty Liver Disease 1,337
- −50List Fatty Liver as a condition, but the registry did not file them under itMost often written as “MASH - Metabolic Dysfunction-Associated Steatohepatitis” (8), “Metabolic Associated Fatty Liver Disease” (7), and “Metabolic Dysfunction-associated Fatty Liver Disease” (7). The registry filed them under other conditions only, most often Diabetes Mellitus, Type 2 (15) and Obesity (13).
- −188Match it another way124 name it in the title, 8 in a keyword, and 56 by a synonym or other text the search reads.
- 661The count on this page65 of them list Fatty Liver in their own words; the registry filed them under no condition.
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What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Status
Who runs them
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (13) · Assiut University (13) · Seoul National University Hospital (7) · Massachusetts General Hospital (6) · Tehran University of Medical Sciences (6) · University of Colorado, Denver (6) · Cairo University (6) · Tanta University (6)
What is being tested here
Drugs under test in Fatty Liver studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Semaglutide | 3 | 0 | 4 |
| Pegozafermin | 2 | 2 | 4 |
| Fructose | 2 | 0 | 3 |
| Probiotic | 2 | 0 | 3 |
| Efimosfermin alfa | 2 | 2 | 2 |
| Tirzepatide | 2 | 1 | 2 |
| Pioglitazone | 1 | 2 | 10 |
| Empagliflozin | 1 | 0 | 5 |
| Obeticholic acid | 1 | 1 | 4 |
| Tesamorelin | 1 | 0 | 2 |
Drug classes tested here GLP-1 receptor agonists 4 open · SGLT2 inhibitors 2 open · Statins 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Ketogenic Diet in MASLD-related cACLD · University of Palermo
- Nov 2026Erdosteine in the Treatment of Nonalcoholic Fatty Liver Disease · Tanta University
- Nov 2026Cilostazol in the Treatment of Nonalcoholic Fatty Liver Disease · Tanta University
- Nov 2026Ursodeoxycholic Acid in Patients With NAFLD - Clinical Observation · General University Hospital, Prague
- Dec 2026Dietary Intervention Study on Liver Health in Young Adults · Hochschule Campus Wien (University of Applied Sciences Campus Vienna)
- Dec 2026Surgical-imaging Research on Obesity (SIRO) · The Affiliated Hospital of Xuzhou Medical University
- Dec 2026Association of HsCAR with MAFLD and Liver Fibrosis: a Cross-sectional Study · Chongqing Medical University
- Dec 2026GLP-1 RA on Alcohol Consumption, Metabolism and Liver Parameters in Patients With Obesity and Fatty Liver Disease · Insel Gruppe AG, University Hospital Bern
- Dec 2026Human Models of Selective Insulin Resistance: Alpelisib, Part I · Columbia University
- Dec 2026Safety, Tolerability, and Bioeffects of Alirocumab in Non-treatment Seeking Heavy Drinkers · National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Who these studies take
Of the 117 Fatty Liver studies recruiting now, 35 (30%) set no upper age limit and 63 (54%) stop at 75 or younger. 8 (7%) take children under 18. 2 (2%) are for women only and 1 (1%) for men only; 32 (27%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (5%) | 5 (4%) |
| 18 | 98 (84%) | 97 (83%) |
| 30 | 109 (93%) | 108 (92%) |
| 40 | 110 (94%) | 109 (93%) |
| 50 | 109 (93%) | 108 (92%) |
| 65 | 100 (85%) | 99 (85%) |
| 75 | 73 (62%) | 72 (62%) |
| 85 | 44 (38%) | 42 (36%) |
Across all 662 studies, recruiting or not: 54% stop at 75 or younger and 29% at 65; 12% take children; 4% are for women only and 4% for men only; 27% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Fatty Liver studies take
Of 41 phase 2 interventional studies under Fatty Liver, half reached primary completion within 24 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 33 mo8–47 · 21 studies | — | — |
| Phase 2 | 24 mo16–36 · 41 studies | — | — |
| Interventional, no phase | 21 mo10–39 · 145 studies | — | 21 mo10–40 · 136 studies |
| Observational | 33 mo20–68 · 96 studies | — | 35 mo21–68 · 87 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
Results posted1
- The Effects of Glucagon on Hepatic MetabolismOct 14, 2026NCT05500586
Stopped1
- Benefit of a Hospital Intervention in Patients With Hepatic SteatosisWithdrawnOct 28, 2026NCT06394206
Newly registered4
- Immunological Signatures of MASLD and MASH in Patients With Type 1 DiabetesNov 10, 2026NCT07927647
- Efficacy of Carnitine Complex in Improving Hepatic Steatosis in Potential Liver DonorsNov 6, 2026NCT07922720
- Effect of Dapagliflozin on Metabolic Parameters in Patients With Non-Alcoholic Fatty Liver DiseaseOct 19, 2026NCT07881796
- Silymarin Effects on Fatty Liver in Type 2 DiabeticsOct 13, 2026NCT07871370
Studies
Recruiting first, then most recently updated. Showing 50 of 662. Browse all 662 → or search them.
- Immunological Signatures of MASLD and MASH in Patients With Type 1 DiabetesNot yet recruitingNCT079276471 country
- Dietary Intervention Study on Liver Health in Young AdultsRecruitingNCT07786831Not applicable1 country
- A Study of INI-822 in Healthy Volunteers and Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH) or Presumed MASHRecruitingNCT05945537Phase 11 country
- Efficacy of Carnitine Complex in Improving Hepatic Steatosis in Potential Liver DonorsNot yet recruitingNCT07922720Not applicable
- A Study to Investigate Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)RecruitingNCT07704892Phase 32 countries
- Trial to Evaluate ALN-CIDEB in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)RecruitingNCT07854782Phase 31 country
- A Pivotal Clinical Study to Investigate the Safety and Efficacy of Efimosfermin Compared With Placebo in Adult Participants With Compensated Cirrhosis Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)RecruitingNCT07701993Phase 32 countries
- A Study of UBT251 in Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH)RecruitingNCT07145151Phase 21 country
- Early Tracking of Childhood Health Determinants (ETCHED) StudyRecruitingNCT034818291 country
- The Effects of Glucagon on Hepatic Metabolism in People With Type 2 Diabetes After Caloric RestrictionNot yet recruitingNCT05499702Phase 21 country
- LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have CirrhosisRecruitingNCT06632457Phase 337 countries
- Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)RecruitingNCT03884075Phase 21 country
- High-Plant-Protein-Diet or High-Animal-Protein-Diet for Improving Alcoholic Fatty Liver DiseaseRecruitingNCT07897981Phase 1/21 country
- Dietary Glycine Supplementation in Metabolic Dysfunction-associated Steatotic Liver DiseaseRecruitingNCT07285135Not applicable1 country
- Exercise for an Aging Liver (EXALIVER)RecruitingNCT07467512Not applicable1 country
- Evaluation of Non-Invasive Tests for Metabolic Liver DiseaseRecruitingNCT071227001 country
- A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASHRecruitingNCT06419374Phase 325 countries
- A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)RecruitingNCT06318169Phase 327 countries
- To Evaluate the Efficacy and Safety of QL2401 in Patients With Metabolic Dysfunction-associated Steatohepatitis and Liver FibrosisNot yet recruitingNCT07620366Phase 2
- Resmetirom in Patients With MASH and HFpEFRecruitingNCT07830758Phase 11 country
- Rezdiffra® With Concomitant Therapies Commonly Used to Treat Comorbidities in Adults With MASH and F2-F3 FibrosisRecruitingNCT07848191Phase 41 country
- A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)RecruitingNCT07165028Phase 334 countries
- Blood Collection Biorepository for Liver Disease ResearchRecruitingNCT030250741 country
- Visceral Adipose Tissue and Liver Changes Associated With Semaglutide in CKDRecruitingNCT071878301 country
- Ultrasound Biomarkers for Assessing Eligibility and Response to Resmetirom TherapyNot yet recruitingNCT078608141 country
- A Trial to Evaluate the Efficacy and Safety of ARO-INHBE in Adults With Metabolic Dysfunction-Associated SteatohepatitisNot yet recruitingNCT07859813Phase 2
- Lifestyle, Dietary Patterns, and Cardiometabolic Risk in Metabolic Dysfunction-Associated Steatotic Liver Disease Among People Living With HIVNot yet recruitingNCT07861594
- Phase 3 Study of the Efficacy, Safety, and Clinical Outcomes of Pemvidutide in MASHRecruitingNCT07795164Phase 31 country
- Pre-hepatectomy Rehabilitation in Obese MASLD-Complicated Living Liver Donors With Mazdutide (PRIME)RecruitingNCT07718126Phase 41 country
- Diagnosis and Quantification of Hepatic Steatosis Using Near-infrared SpectroscopyNot yet recruitingNCT07254533Not applicable1 country
- Impact of Overt and Subclinical Hypothyroidism on Liver Fibrosis in Patients With MASLDNot yet recruitingNCT07827430
- A Single-Dose Pharmacokinetic Study of HRS-4729 Injection in Healthy Participants and Patients With Renal ImpairmentRecruitingNCT07807059Phase 11 country
- Dynamic Changes and Risk Factors of Fibrosis and Steatosis Progression in Nonalcoholic Fatty Liver DiseaseRecruitingNCT036355411 country
- Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic(PK/PD) Profile of ACT500 in Metabolic Dysfunction-Associated Steatotic Liver Disease(MASLD)Not yet recruitingNCT07462455Phase 11 country
- ECC4703 Food Effect and Relative Bioavailability Study in Healthy Adult ParticipantsRecruitingNCT07334080Phase 11 country
- A Study of VV-14303 for the Treatment of Metabolic Dysfunction-associated Steatohepatitis (MASH)RecruitingNCT07732400Phase 1/22 countries
- A Study of HRS-4729 Injection and HRS9531 Injection in Participants With Metabolic Dysfunction-Associated SteatohepatitisRecruitingNCT07660848Phase 21 country
- Human Models of Selective Insulin Resistance: Alpelisib, Part IRecruitingNCT06354088Phase 11 country
- Detecting Liver Fibrosis in Patients At-riskNot yet recruitingNCT077756381 country
- GLP-1 RA on Alcohol Consumption, Metabolism and Liver Parameters in Patients With Obesity and Fatty Liver DiseaseNot yet recruitingNCT06546384Not applicable1 country
- Development of a Non-invasive Screening Tool to Predict Metabolic Dysfunction-associated Steatotic Liver DiseaseRecruitingNCT048732581 country
- Acute Exercise and Endogenous Glucose Production in Type 2 Diabetes: Implications for Glycemic Control and Treatment of Hepatic SteatosisRecruitingNCT06993454Not applicable1 country
- Metabolic Flux Analysis in Metabolic Dysfunction-Associated Steatotic Liver DiseaseNot yet recruitingNCT07760909Not applicable
- Effects of Peanut Consumption on Adults With Metabolic Associated Fatty Liver DiseaseRecruitingNCT07646197Not applicable1 country
- A Study to Investigate the Safety and Efficacy of GSK4532990 Compared With Placebo in Adult Participants Aged 18 to 70 Years With Alcohol-related Liver DiseaseRecruitingNCT06613698Phase 218 countries
- Fructose is a Metabolic and Inflammatory Pathogenic Factor in Metabolic Dysfunction-associated Steatohepatitis (MASH)RecruitingNCT07013916Not applicable1 country
- Metabolic Liver Disease in Newly Diagnosed People Living With HIV (MASHIV-TR)RecruitingNCT077373401 country
- Biomarker Panel for PCOS-Associated Liver Steatosis in Adolescent Girls (COMPASS-pedPCOS)Not yet recruitingNCT077313731 country
- Safety, Tolerability, and Bioeffects of Alirocumab in Non-treatment Seeking Heavy DrinkersRecruitingNCT04781322Phase 11 country
- Taiwan Green Propolis for Blood Lipids and Body Fat in Patients With MASLDRecruitingNCT07692438Not applicable1 country