Drug
Phenytoin clinical trials
Also written Dilantin.
- studies test it
- 49
- open now
- 4
- in phase 3
- 6
- first study started
- 1996
Keep track of what changes. Save the Phenytoin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
Combined with it in one product
Studies by the year they started
49 studies that test it; most in 2007 (4)
| Year | Studies |
|---|---|
| 1996 | 1 |
| 1997 | 1 |
| 1999 | 1 |
| 2003 | 1 |
| 2004 | 1 |
| 2005 | 1 |
| 2006 | 3 |
| 2007 | 4 |
| 2008 | 2 |
| 2009 | 1 |
| 2010 | 3 |
| 2011 | 3 |
| 2012 | 2 |
| 2015 | 3 |
| 2017 | 3 |
| 2020 | 1 |
| 2021 | 3 |
| 2022 | 2 |
| 2023 | 2 |
| 2024 | 4 |
| 2025 | 4 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 21
- Phase 2
- 7
- Phase 3
- 6
- Phase 4
- 10
- No phase
- 8
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 18 · Other 31
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. (3) · BeiGene (2) · Merck Sharp & Dohme LLC (2) · Mansoura University (2) · University of Texas Southwestern Medical Center (2) · Al-Azhar University (1) · Arcus Biosciences, Inc. (1) · Aalborg University (1)
Often tested with
Tested in the same studies.
Itraconazole (8) · Levetiracetam (7) · Valproic Acid (4) · Carbamazepine (4) · Lamotrigine (3) · Topiramate (3) · Midazolam (2) · Paroxetine (2)
Studies
Open first, then newest update. How each study uses Phenytoin is read from its arms, and is right about nine times in ten.
Testing it · 49
- A Study to Investigate the Effect of the CYP3A Inducer Phenytoin and the CYP3A Inhibitor Itraconazole on the Pharmacokinetics of BGB-58067 in Healthy ParticipantsRecruitingPhase 1BeOne MedicinesNCT07590102Written as Phenytoin
- A Drug-drug Interaction Study to Assess the Effect of Phenytoin and Itraconazole on the Pharmacokinetics of Pelabresib in Healthy ParticipantsRecruitingPhase 1Novartis PharmaceuticalsNCT07783503Written as Phenytoin
- Topical Phenytoin for Management of Gingival RecessionNot yet recruitingPhase 2/3Cairo UniversityNCT07590375Written as phenytoin cream
- Pharmacological Management of Seizures Post Traumatic Brain InjuryNot yet recruitingPhase 3Cambridge University Hospitals NHS Foundation TrustNCT04573803Written as Phenytoin Sodium
- Compairing Micro Needling With Phenytoin Versus Microneedling Alone on Striae AlbaCompletedNot applicableAl-Azhar UniversityNCT07841366Written as Phenytoin
- Effect of Phenytoin or Itraconazole on How BGB-16673 is Absorbed and Removed From the Body in Healthy ParticipantsCompletedPhase 1BeiGeneNCT06906809Written as Phenytoin
- A Study of the Effect of Itraconazole and Phenytoin on Calderasib (MK-1084) in Healthy Adults (MK-1084-008)CompletedPhase 1Merck Sharp & Dohme LLCNCT06719557Written as Phenytoin
- Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29)CompletedPhase 1Arcus Biosciences, Inc.NCT06919991Written as Phenytoin
- A Clinical Study of Belzutifan (MK-6482) Alone or With Phenytoin in Healthy Participants (CA46602/MK-6482-035)CompletedPhase 1Merck Sharp & Dohme LLCNCT06903715Written as Phenytoin
- Pharmacological Modulation of Peripheral Nerve ExcitabilityCompletedNot applicableAalborg UniversityNCT06312254Written as Topical Phenytoin 10%
- A Study to Evaluate the Effects of Phenytoin and Itraconazole on Sonrotoclax (BGB-11417) in Healthy VolunteersCompletedPhase 1BeiGeneNCT06543043Written as Phenytoin
- Effect of Phenytoin Cream on Wound Healing After Anal Fissure Surgery.CompletedPhase 1Mansoura UniversityNCT06633185Written as phenytoin cream
- A Study to Learn How Different Forms of The Study Medicine Called Phenytoin Are Taken up Into the Blood in Healthy AdultsCompletedPhase 1PfizerNCT06466473Written as Phenytoin (Ascoli)
- DDI Study of ASC41 in HV and the PK, Safety and Tolerability in Subjects With NAFLD.CompletedPhase 1Gannex Pharma Co., Ltd.NCT04845646Written as Phenytoin
- A Study to Assess the Effect of Phenytoin on the Drug Levels of Afimetoran and the Effect of Afimetoran on the Drug Levels of MidazolamCompletedPhase 1Bristol-Myers SquibbNCT05901714Written as Phenytoin
- Efficacy of Phenytoin vs Levetiracetam in Status Epilepticus at Institute of Child Health,FaisalabadCompletedNot applicableShaheed Zulfiqar Ali Bhutto Medical UniversityNCT06067412Written as Phenytoin
- Phenytoin Cream for the Treatment of Neuropathic PainCompletedPhase 2/3David J. KopskyNCT04647877Written as phenytoin cream
- Study on the Efficacy of Phenytoin in the Prophylaxis of Seizures of Patients With Pneumococcal Meningitis at Least 50 Yrs Old.TerminatedPhase 4M. Carmen Cabellos MinguezNCT01478035Written as Phenytoin
- The Benefit and Safety of Older Generation Anti-Epileptic Drugs (AEDs) in Drug-Resistant Epilepsy ChildrenStatus unknownPhase 4Dr Cipto Mangunkusumo General HospitalNCT05697614Written as Phenytoin
- A Study to Evaluate the Effect of Multiple Doses of Itraconazole, Phenytoin, and Paroxetine on the Single-Dose Pharmacokinetics of Poziotinib in Healthy Adult ParticipantsCompletedPhase 1Spectrum Pharmaceuticals, IncNCT04981704Written as Phenytoin
See all 49 studies that test Phenytoin →
Given in every arm · 4 — Phenytoin is usual care beside what is tested
- Determinants of Warfarin MetabolismRecruitingNot applicableHadassah Medical OrganizationNCT00162474Written as Phenytoin
- Clinical Study Evaluating Safety of Pentoxifylline and Celecoxib in Patients With Grand-Mal Epilepsy Treated by Phenytoin MonotherapyRecruitingPhase 2Mostafa BahaaNCT05637086Written as Phenytoin
- Treatment of Nodding Syndrome - A Randomized Blinded Placebo-Controlled Crossover Trial of Oral Pyridoxine and Conventional Anti-Epileptic Therapy, in Northern Uganda - 2012WithdrawnPhase 2Centers for Disease Control and PreventionNCT01730313Written as Phenytoin
- Busulfan, Fludarabine, and Total-Body Irradiation in Treating Patients Who Are Undergoing a Donor Stem Cell Transplant for Hematologic CancerCompletedPhase 1/2OHSU Knight Cancer InstituteNCT00245037Written as Phenytoin
As the comparator · 5 — what is tested is compared with Phenytoin
- Early Post-Traumatic Seizures Prevention Trial (E-PTS Trial)RecruitingPhase 4All India Institute of Medical Sciences, JodhpurNCT07072624Written as Phenytoin
- Levetiracetam Versus Phenytoin in Management of Pediatric Status EpilepticusStatus unknownPhase 4Tanta UniversityNCT04176887Written as Phenytoin Injection
- Efficacy Evaluation of Intravenous Brivaracetam and Phenytoin in Subjects With Nonconvulsive Electrographic SeizuresTerminatedPhase 2UCB BIOSCIENCES, Inc.NCT02088957Written as Phenytoin intravenous solution
- Comparative Trial of IV Lacosamide Versus Phenytoin for Seizure ManagementTerminatedPhase 4London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph'sNCT02409433Written as Phenytoin
- The Effect of BIA 2-093 on the Steady-state Pharmacokinetic Profile of Phenytoin in PatientsTerminatedPhase 1Bial - Portela C S.A.NCT01878578Written as phenytoin
Codes
What other systems call Phenytoin · ClinicalTrials.gg INT008003
- MeSH (NLM) D010672PhenytoinConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 6158TKW0C5PHENYTOINConfirmed FDA, NLM, Wikidata
- RxNorm 8183Confirmed FDA, Wikidata
- Wikidata Q410400phenytoinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C741PhenytoinOne source FDA
- DrugBank DB00252One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D010672 | Phenytoin | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 6158TKW0C5 | PHENYTOIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 8183 | — | Confirmed FDA, Wikidata |
| Wikidata | Q410400 | phenytoin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C741 | Phenytoin | One source FDA |
| DrugBank | DB00252 | — | One source Wikidata |
Also registered as phenytoin sodium (UNII 4182431BJH · RxNorm 71227).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.