Drug
Topiramate clinical trials
Also written Topamax, Topomax, USL255 and TPM.
- studies test it
- 224
- open now
- 14
- in phase 3
- 70
- first study started
- 1992
Keep track of what changes. Save the Topiramate studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
217 studies that test it; most in 2001 (22)
| Year | Studies |
|---|---|
| 1992 | 1 |
| 1993 | 2 |
| 1994 | 3 |
| 1995 | 1 |
| 1997 | 1 |
| 1998 | 2 |
| 1999 | 1 |
| 2000 | 8 |
| 2001 | 22 |
| 2002 | 6 |
| 2003 | 10 |
| 2004 | 19 |
| 2005 | 11 |
| 2006 | 7 |
| 2007 | 19 |
| 2008 | 14 |
| 2009 | 6 |
| 2010 | 6 |
| 2011 | 5 |
| 2012 | 7 |
| 2013 | 7 |
| 2014 | 8 |
| 2015 | 4 |
| 2016 | 4 |
| 2017 | 7 |
| 2018 | 2 |
| 2019 | 4 |
| 2020 | 5 |
| 2021 | 4 |
| 2022 | 8 |
| 2023 | 2 |
| 2024 | 4 |
| 2025 | 4 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 4
- Phase 1
- 27
- Phase 2
- 65
- Phase 3
- 70
- Phase 4
- 54
- No phase
- 17
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 89 · Other 135
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (49) · VIVUS LLC (12) · Bankole Johnson (6) · University of Minnesota (5) · University of California, Irvine (4) · University of Pennsylvania (4) · University of California, San Francisco (4) · University of Florida (3)
Often tested with
Tested in the same studies.
Phentermine (22) · Valproic Acid (6) · Amitriptyline (6) · Nortriptyline (5) · Propranolol (5) · Naltrexone (5) · Zonisamide (4) · Carbamazepine (4)
Studies
Open first, then newest update. How each study uses Topiramate is read from its arms, and is right about nine times in ten.
Testing it · 224
- Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric SurgeryRecruitingPhase 4University of California, IrvineNCT05975580Written as Topiramate
- Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison StudyRecruitingPhase 4Mayo ClinicNCT06972056Written as Topiramate 100 mg
- Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and LymphomaNot yet recruitingPhase 2St. Jude Children's Research HospitalNCT07790913Written as Phentermine/Topiramate ER
- Treatment of Meniere's Disease With Migraine MedicationsRecruitingPhase 4University of California, IrvineNCT05582837Written as nortriptyline + topiramate
- Individualized Pharmacological Approach to Obesity in Patients With Bipolar DisorderRecruitingPhase 4Mayo ClinicNCT07213466Written as Phentermine-Topiramate
- Combining Latency Reversing Agents to Address the HIV ReservoirNot yet recruitingPhase 1/2Erasmus Medical CenterNCT07384624Written as Topiramate (drug)
- Leveraging Biomarkers for Personalized Treatment of Alcohol Use Disorder Comorbid With PTSDRecruitingPhase 2NYU Langone HealthNCT03667846Written as Topiramate
- Qudexy XR for the Prevention of Migraine in Children 6 to 11 Years OldRecruitingPhase 4Upsher-Smith LaboratoriesNCT04748601Written as Qudexy XR
- Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary CareNot yet recruitingPhase 4Fundacio d'Investigacio en Atencio Primaria Jordi Gol i GurinaNCT06499116Written as Topiramate
- Lacosamide Versus Topiramate in MigraineRecruitingPhase 3Kafrelsheikh UniversityNCT06243692Written as Topiramate 50Mg Tab
- Studying Topiramate for Re-Activating the HIV-1 ReservoirNot yet recruitingPhase 1/2Erasmus Medical CenterNCT06282783Written as Topiramate
- The Role of Migraine Prophylaxis Agent Topiramate in Treating Patients With Sudden Sensorineural Hearing LossRecruitingPhase 2Chang Gung Memorial HospitalNCT05403229Written as Topiramate
- Zolmitriptane as Prophylaxis for Chilhood MigraineRecruitingPhase 4Tanta UniversityNCT06089356Written as topiramate
- Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese PatientsRecruitingPhase 2University of California, San DiegoNCT04721873Written as Phentermine-Topiramate
- Sequential Therapy Anti-obesitY Medication With Muscle Preservation for Weight Loss and MaintEnance: A PragmAtic Randomized CoNtrolled Trial (STAY-LEAN Trial)Active, not recruitingPhase 4The Cleveland ClinicNCT06854614Written as Phentermine-Topiramate
- Pharmacokinetics and Pharmacodynamics of Topiramate for Weight Loss in Youth: PHARMATOPCompletedEarly Phase 1University of MinnesotaNCT04986631Written as Topiramate Tablets
- Phentermine/Topiramate for Uric Acid StonesCompletedPhase 2University of FloridaNCT04621929Written as Phentermine / Topiramate Oral Product
- Topiramate and Schizophrenia: Effects on Weight and PsychopathologyActive, not recruitingNot applicableCentre for Addiction and Mental HealthNCT02808533Written as Topiramate
- Topiramate Augmenting Strategies for the Treatment of Alcohol Use DisorderCompletedEarly Phase 1Nassima Ait-Daoud TiouririneNCT03120468Written as Topiramate and N-Acetyl Cysteine
- Zonisamide Versus Topiramate in MigraineCompletedPhase 3Kafrelsheikh UniversityNCT06347497Written as Topiramate 50 MG
See all 224 studies that test Topiramate →
Given in every arm · 3 — Topiramate is usual care beside what is tested
- Individualized Obesity PharmacotherapyCompletedPhase 3Mayo ClinicNCT03374956Written as Phentermine-Topiramate
- A Study to Evaluate How VI-0521 Affect Psychomotor Performance in Healthy Overweight and Obese Subjects.CompletedPhase 2VIVUS LLCNCT00806260Written as VI-0521
- NINDS CRC Chronic Migraine Treatment TrialCompletedPhase 3Anne LindbladNCT00772031Written as topiramate
As the comparator · 14 — what is tested is compared with Topiramate
- Comparing Migraine Preventive Therapies vs. Anti-CGRP Therapies for Tinnitus in Patients With Migraine (COMPACT-PM)Not yet recruitingPhase 4Stanford UniversityNCT07655440Written as topiramate
- Modified Atkins Diet Versus Topiramate In Children With Epileptic Spasms Refractory To Hormonal Treatment: A Randomized Open-Label StudyRecruitingPhase 2/3Lady Hardinge Medical CollegeNCT05958160Written as Topiramate
- Comparative Study of Oral Atogepant Versus Oral Topiramate to Assess Adverse Events in Adult Participants With MigraineCompletedPhase 3AbbVieNCT05748483Written as Topiramate
- A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in AmericaCompletedPhase 4Novo Nordisk A/SNCT05579249Written as Phentermine/Topiramate
- Transcutaneous Supraorbital Nerve Stimulator Versus Topiramate in Prevention of Recurrent MigraineStatus unknownNot applicableTongji HospitalNCT05516251Written as Topiramate 25Mg Tab
- Head-to-head Study of Erenumab Against Topiramate in Patients With Episodic and Chronic MigraineCompletedPhase 4Novartis PharmaceuticalsNCT03828539Written as Topiramate
- EQW, DAPA, EQW/DAPA, DAPA/MET ER and PHEN/TPM ER in Obese Women With PolycysticOvary Syndrome (PCOS)CompletedPhase 3Woman'sNCT02635386Written as Phentermine /Topiramate (PHEN/ TPM) ER
- Levetiracetam Versus Topiramate as Adjunctive Therapy to Evaluate Efficacy and Safety in Subjects With Refractory Partial Onset SeizuresCompletedPhase 4UCB Korea Co., Ltd.NCT01229735Written as Topiramate
- Efficacy and Safety of DanzhenStatus unknownPhase 1Xijing HospitalNCT02645370Written as Topiramate
- Flunarizine Versus Topiramate for Chronic Migraine ProphylaxisCompletedPhase 4Taipei Veterans General Hospital, TaiwanNCT02639598Written as Topiramate
- Interdisciplinary Study of Two Novel Anticonvulsants in AlcoholismTerminatedPhase 2Boston Medical CenterNCT00862563Written as Topiramate
- Acupuncture in Chronic Migraine: A Randomized Controlled TrialCompletedNot applicableKuang Tien General HospitalNCT01096420Written as topiramate
- Carisbamate Retention Study (CaReS): Comparative Study on the Long Term Effectiveness, Safety and Tolerability of Carisbamate Compared to Two Other Frequently Prescribed Anti-epileptic Drugs (AEDs) in Patients With Epilepsy.TerminatedPhase 3SK Life Science, Inc.NCT00563459Written as topiramate
- A Multicenter Comparative Trial of Zonisamide and Topiramate as Initial Monotherapy in Untreated EpilepsiesCompletedPhase 4Eisai Korea Inc.NCT00154076Written as Topiramate
Codes
What other systems call Topiramate · ClinicalTrials.gg INT006673
- MeSH (NLM) D000077236TopiramateConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 0H73WJJ391TOPIRAMATEConfirmed FDA, NLM, Wikidata
- RxNorm 38404Confirmed FDA, Wikidata
- Wikidata Q221174topiramateConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47764TopiramateOne source FDA
- DrugBank DB00273One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077236 | Topiramate | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 0H73WJJ391 | TOPIRAMATE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 38404 | — | Confirmed FDA, Wikidata |
| Wikidata | Q221174 | topiramate | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47764 | Topiramate | One source FDA |
| DrugBank | DB00273 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.