Osteonecrosis clinical trials

The registry lists 180 studies for Osteonecrosis across more than 10 countries. 31 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-23.

Studies

Recruiting first, then most recently updated. Showing 50 of 180 — search for more.

• Daycase Hip and Knee Arthroplasty in Møre and Romsdal TrialNot yet recruitingNCT078340341 country
• Autologous Bone Marrow Aspirate Treatment for Early-Stage OsteonecrosisRecruitingNCT06123481Not applicable1 country
• Exactech Shoulder Post Market Clinical Follow-up StudyRecruitingNCT056037286 countries
• Patient Specific Talus Spacer Post Approval StudyRecruitingNCT053646061 country
• Emerging Indications for Hyperbaric Oxygen TreatmentNot yet recruitingNCT07240649Phase 4
• Bone Marrow Injection in Fracture of Femoral NeckRecruitingNCT07808294Not applicable1 country
• Perform Humeral System StudyRecruitingNCT050675435 countries
• Alendronate for Osteonecrosis in Adults With Sickle Cell DiseaseRecruitingNCT06016634Phase 21 country
• Effect of HBOT on Femoral Head Avascular Necrosis (AVN)Not yet recruitingNCT06931301Not applicable1 country
• Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Shoulder Prosthesis SystemRecruitingNCT076780341 country
• 3D Printing Models in Surgical Planning of Osteotomies in Kienbock´s Disease Stages II-IIIRecruitingNCT064609221 country
• Intraoperative Contrast-Enhanced Ultrasound Evaluation of Blood Flow at the Time of Surgical Hip Reduction for DDHRecruitingNCT03107520Early Phase 11 country
• Marrow Cellution™ vs. Traditional BMA Harvest ProjectRecruitingNCT06388993Not applicable1 country
• Tornier HRS (Humeral Reconstruction System) Study (REVIVE)Enrolling by invitationNCT055000661 country
• Prospective Evaluation of Clinical and Radiographic Outcomes Following Total Talus Replacement (PROCLAIM)Enrolling by invitationNCT063113311 country
• Study of the Clinical and Radiographic Results of a Fixed Polyethylene Posteriorly Stabilized Cemented Total Knee Prosthesis With a Minimum Follow-up of 1 Year.RecruitingNCT073134491 country
• G7 Freedom Constrained Vivacit-E LinersEnrolling by invitationNCT05587244Not applicable1 country
• Clinical and Radiological Outcomes of Medacta Shoulder System FRRecruitingNCT059266221 country
• MRONJ and Polynucleotides-Hyaluronic Acid Hydrogel (Regenfast®)Not yet recruitingNCT06984107Not applicable
• Partial Synovectomy in Articular Side of Quadriceps Tendon Verified to Reduce Crepitus in Retrospective StudyRecruitingNCT06129214Not applicable1 country
• Human Amniotic Membrane (hAM) for Stage II Maxillomandibular Osteonecrosis ManagementRecruitingNCT05664815Phase 21 country
• Medication Related Osteonecrosis of the Jaws (MRONJ) in a Cohort of Patients Treated by Antiresorptive DrugsRecruitingNCT064577761 country
• Therapeutic Exposures and Risk Factors in MRONJRecruitingNCT064307621 country
• Immunological Parameters Between MRONJ StagesRecruitingNCT064202841 country
• Leukocyte- and Platelet-Rich Fibrin in the Surgical Treatment of Medication-related Osteonecrosis of the JawNot yet recruitingNCT06419010Not applicable1 country
• Local and Systemic Changes in Osteonecrosis of the JawboneEnrolling by invitationNCT053295581 country
• The KinematX Midcarpal Total Wrist Arthroplasty RegistryRecruitingNCT057199351 country
• Best Treatment Choice for Osteonecrosis of the JawRecruitingNCT04512638Phase 41 country
• PROMIS Evaluation StudyRecruitingNCT057346511 country
• Prospective Registry of Prosthodontic Rehabilitation in Oncology Patients Undergoing Jaw ReconstructionRecruitingNCT026611391 country
• Validation of the O-bridge Protocol: a Prospective, Multicenter TrialRecruitingNCT040077831 country
• Sickle Cell Disease (SCD) Bone Pain StudyActive, not recruitingNCT05283148Not applicable1 country
• Persona Ti-Nidium Post-Market Clinical Follow-upActive, not recruitingNCT04817969Not applicable1 country
• Early Feasibility Study of Cartilage Defect RepairActive, not recruitingNCT06823089Not applicable1 country
• Deep Learning for Automatic Segmentation of Bone Sequestra on Orthopantomographs: A UNet-Based ApproachCompletedNCT078090481 country
• Pyrocarbon Clinical Follow-up StudyActive, not recruitingNCT050499931 country
• Anatomical Shoulder Domelock System StudyActive, not recruitingNCT033124654 countries
• Hypertension Intervention to Reduce Osteonecrosis in Children With Acute Lymphoblastic Leukemia/LymphomaCompletedNCT04401267Phase 21 country
• Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)Active, not recruitingNCT057878211 country
• Database Retrieval for the Comprehensive ShoulderActive, not recruitingNCT034097181 country
• TESS V3 Modular Total Shoulder System PMCFTerminatedNCT050029591 country
• Sidus(TM) Post Market Clinical Follow-up (PMCF) StudyCompletedNCT017005435 countries
• Insignia™ Hip Stem Outcomes StudyActive, not recruitingNCT05144191Not applicable1 country
• Pentoxifylline and Tocopherol (PENTO) in the Treatment of Medication-related Osteonecrosis of the Jaw (MRONJ)Active, not recruitingNCT03040778Phase 31 country
• Outcomes Study of the Trabecular Metal (TM) Reverse Shoulder SystemActive, not recruitingNCT014804402 countries
• Cemented vs Cementless Persona Keel RCTActive, not recruitingNCT05630053Not applicable1 country
• Persona Partial Knee Clinical Outcomes StudyActive, not recruitingNCT03034811Not applicable10 countries
• RAB001（LLP2A-Ale） in Healthy SubjectsCompletedNCT07545018Phase 11 country
• Comprehensive Nano - Post Market Clinical Follow-Up StudyActive, not recruitingNCT034239534 countries
• The Use of Genex in the Management of Early-Stage Osteonecrosis of the Femoral HeadActive, not recruitingNCT057069091 country