Dysmenorrhea clinical trials
The registry lists 430 studies for Dysmenorrhea across more than 10 countries. 107 are recruiting or about to start. 342 of them are mainly about Dysmenorrhea (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Status
Who runs them
Cairo University (32) · Riphah International University (21) · Bayer (11) · AbbVie (7) · Nobelpharma (6) · Organon and Co (5) · Abbott (4) · Hacettepe University (4)
What is being tested here
Drugs under test in Dysmenorrhea studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Elagolix | 1 | 7 | 9 |
| Naproxen | 1 | 2 | 6 |
| Norethindrone | 1 | 4 | 5 |
| Acetaminophen | 1 | 0 | 4 |
| Norethindrone Acetate | 1 | 2 | 3 |
| Desloratadine | 1 | 0 | 1 |
| Magnesium Sulfate | 1 | 0 | 1 |
| Propolis | 1 | 0 | 1 |
| Linzagolix | 0 | 4 | 5 |
| Relugolix | 0 | 3 | 3 |
Drug classes tested here NSAIDs 1 open · Hormonal contraceptives 1 open · COX-2 inhibitors 5 · Estrogens 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Feb 2027Efficacy and Safety of DEH113 in the Treatment of Menstrual Cramp Pain Associated With Primary Dysmenorrhea · Phase 3 · EMS
- Jul 2027Study Of Oral Elagolix Tablets In Combination With Combined Oral Contraceptive Capsules/Tablets To Assess Dysmenorrhea Response In Adult Female Participants With Endometriosis And Associated Moderate To Severe Pain · Phase 3 · AbbVie
- Nov 2026Diaphragm-Pelvic Floor Synergy Training in Young Females With Primary Dysmenorrhea. · Riphah International University
- Nov 2026Effera Dose Response: Women's Health · Helaina Inc.
- Nov 2026Vibration, Massage, and Myofascial Release in Primary Dysmenorrhea · Istanbul Medipol University Hospital
- Nov 2026Effect of Pilates Exercises Versus Gym Exercises On Primary Dysmenorrhea · Cairo University
- Dec 2026Effect of Semiconductor Embedded Wearable Sleeve on Treatment of Primary Dysmenorrhea Symptoms · University of California, Davis
- Dec 2026The Effect of Cognitive Exercise Therapy Approach and Yoga in Adolescents With Dysmenorrhoea · Acibadem University
- Dec 2026Relationship Between Primary Dysmenorrhea and Biomechanical Characteristics of Lumbo-pelvic Region Among Female University Students · Cairo University
- Dec 2026Self-Acupressure for Primary Dysmenorrhea and Premenstrual Symptoms · Nigde Omer Halisdemir University
Who these studies take
Of the 57 Dysmenorrhea studies recruiting now, 7 (12%) set no upper age limit and 49 (86%) stop at 75 or younger. 11 (19%) take children under 18. 56 (98%) are for women only and 0 (0%) for men only; 20 (35%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (4%) | 0 (0%) |
| 18 | 48 (84%) | 1 (2%) |
| 30 | 40 (70%) | 1 (2%) |
| 40 | 27 (47%) | 1 (2%) |
| 50 | 16 (28%) | 1 (2%) |
| 65 | 9 (16%) | 1 (2%) |
| 75 | 8 (14%) | 1 (2%) |
| 85 | 8 (14%) | 1 (2%) |
Across all 430 studies, recruiting or not: 84% stop at 75 or younger and 84% at 65; 22% take children; 98% are for women only and 0% for men only; 36% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Dysmenorrhea studies take
Of 17 phase 3 interventional studies under Dysmenorrhea, half reached primary completion within 28 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 28 mo19–30 · 17 studies | — | — |
| Interventional, no phase | 8 mo3–16 · 188 studies | — | 8 mo4–16 · 178 studies |
| Observational | 23 mo4–47 · 22 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Effect of Virtual Reality on Pain and Anxiety in Women With DysmenorrheaNov 9, 2026NCT07853508
Newly registered5
- Radiofrequency and Pelvic Floor Exercise for Primary DysmenorrheaNov 6, 2026NCT07921381
- PRECISION-E2: Teverelix in Women With Endometriosis - Pharmacodynamics, Safety and Precision Medicine CorrelatesNov 3, 2026NCT07914062
- Ultrasound-Guided Radiofrequency Ablation for Focal AdenomyosisOct 30, 2026NCT07906535
- The Effect of a Ginger Formula on Menstrual Health vs a PlaceboOct 26, 2026NCT07894406
- Transcutaneous Cervical Vagus Nerve Stimulation for Primary DysmenorrheaOct 19, 2026NCT07880080
Studies
Recruiting first, then most recently updated. Showing 50 of 430. Browse all 430 → or search them.
- Radiofrequency and Pelvic Floor Exercise for Primary DysmenorrheaNot yet recruitingNCT07921381Not applicable
- Effect of Virtual Reality on Pain and Anxiety in Women With DysmenorrheaRecruitingNCT07853508Not applicable1 country
- PRECISION-E2: Teverelix in Women With Endometriosis - Pharmacodynamics, Safety and Precision Medicine CorrelatesNot yet recruitingNCT07914062Phase 2
- Ultrasound-Guided Radiofrequency Ablation for Focal AdenomyosisNot yet recruitingNCT07906535Not applicable1 country
- The Effect of a Ginger Formula on Menstrual Health vs a PlaceboNot yet recruitingNCT07894406Not applicable
- Transcutaneous Cervical Vagus Nerve Stimulation for Primary DysmenorrheaNot yet recruitingNCT07880080Not applicable
- Association of Ultrasound Features of the Myometrium Suggestive of Adenomyosis and Clinical SymptomsRecruitingNCT073977154 countries
- The Effect of Cognitive Exercise Therapy Approach and Yoga in Adolescents With DysmenorrhoeaRecruitingNCT06398990Not applicable1 country
- The Effect of Hydrogen-Rich Water on Dysmenorrhea and Menstrual Symptom SeverityNot yet recruitingNCT07865000Not applicable
- Whole-Body Vibration and Aerobic Exercise for Primary Dysmenorrhea in Young Adult WomenNot yet recruitingNCT07859124Not applicable
- Heavy Menstrual Bleeding and Dysmenorrhea Among Undergraduate Females in the Faculty of Medicine of Assiut UniversityNot yet recruitingNCT07852143
- Impact of OMT on the Symptoms of DysmenorrheaRecruitingNCT07849140Not applicable1 country
- Vaginal Sildenafil for Primary DysmenorrheaNot yet recruitingNCT07508358Phase 11 country
- Effects of Sacral Release Technique and Lumbar Mobilization in Primary Dysmenorrhea.RecruitingNCT07576231Not applicable1 country
- Use of tDCS Stimulation in Neurological and Gynaecological ConditionsRecruitingNCT06891690Not applicable1 country
- Effects of Transcutaneous Tibial and Auricular Vagus Nerve Stimulation in Females With Primary DysmenorrheaNot yet recruitingNCT07834658Not applicable
- Individualized Acupoint Therapy for Dysmenorrhea: An Exploratory Research Design Based on Meridian MeasurementNot yet recruitingNCT07818044Not applicable1 country
- Anti-Inflammatory Diet and Physical Activity for Reproductive Health in Adolescent GirlsRecruitingNCT07834489Not applicable1 country
- Impact of the Antihistamine Desloratadine on the Quality of Life and Dysmenorrhea in Patients With EndometriosisNot yet recruitingNCT07821320Phase 21 country
- Effects of a Combined Home-Based Exercise Program on Menstrual Pain, Dual-Task Gait Performance, and EEG Markers of Cognitive-Motor Control in Females With Primary DysmenorrheaNot yet recruitingNCT07436507Not applicable
- Brain and Blood Vessel Health Following Endometriosis Treatment in People With EndometriosisNot yet recruitingNCT07799246Phase 4
- Effectiveness of an Acupressure Band for Primary Dysmenorrhea in College StudentsRecruitingNCT07794995Not applicable1 country
- Diaphragm-Pelvic Floor Synergy Training in Young Females With Primary Dysmenorrhea.RecruitingNCT07754305Not applicable1 country
- Study on the Outcomes of Patients Treated in Gynecological Emergency Departments for Pelvic Endometriosis or Suspected Pelvic EndometriosisRecruitingNCT07472842Not applicable1 country
- Prevalence of Childhood Maltreatment Among Women With Dysmenorrhea.Enrolling by invitationNCT07786688Not applicable1 country
- Self-Acupressure for Primary Dysmenorrhea and Premenstrual SymptomsRecruitingNCT07409337Not applicable1 country
- Abdominopelvic Fascial Release for Post-Cesarean Menstrual Pain and Scar MobilityNot yet recruitingNCT07717983Not applicable
- Pelvic Floor Physical Therapy and Exercise for Women With Endometriosis and Chronic Pelvic PainRecruitingNCT07733583Not applicable1 country
- Vibration, Massage, and Myofascial Release in Primary DysmenorrheaRecruitingNCT07731243Not applicable1 country
- Evaluation of the Effect of a Structured Yoga Exercise in Young Women With Primary DysmenorrheaRecruitingNCT07520136Not applicable1 country
- Relationship Between Primary Dysmenorrhea and Biomechanical Characteristics of Lumbo-pelvic Region Among Female University StudentsNot yet recruitingNCT07702214
- Evaluation of the Analgesic Effect of Intramyometrial Botulinum Toxin Injection Via Hysteroscopy in Pelvic Pain Suggestive of DysmenorrheaRecruitingNCT06995287Phase 31 country
- Menstrual Cycle Symptoms and Female HealthRecruitingNCT076992241 country
- CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of LifeRecruitingNCT076790741 country
- Effect of Pilates Exercises Versus Gym Exercises On Primary DysmenorrheaNot yet recruitingNCT07669883Not applicable
- Emotional Freedom Techniques in Nursing Students With Primary DysmenorrheaNot yet recruitingNCT07658859Not applicable
- Effect of Semiconductor Embedded Wearable Sleeve on Treatment of Primary Dysmenorrhea SymptomsNot yet recruitingNCT07176780Not applicable
- Comparative Effects of Neurodynamic Stretch and Myofascial Pain Release in Polycystic Ovarian Syndrome.RecruitingNCT07645014Not applicable1 country
- Effects of Physiotherapy on Ultrasound and Clinical Parameters in Women With DysmenorrheaNot yet recruitingNCT07645196Not applicable1 country
- Impact of Ehlers-Danlos Syndrome on Gynaecological HealthRecruitingNCT071512741 country
- Comparative Effects of Aerobic Exercises and Jacobson's Progressive Relaxation Technique in Primary DysmenorrheaRecruitingNCT07628452Not applicable1 country
- Graded Motor Imagery for Primary DysmenorrheaRecruitingNCT07618832Not applicable1 country
- Intervention in Executive Functions and Emotional Self-Regulation in Adolescents With Primary DysmenorrheaNot yet recruitingNCT07555886Not applicable1 country
- Pelvic Nerve Mobilization for Primary DysmenorrheaRecruitingNCT07354451Not applicable1 country
- The Good Pain Consultation in Endometriosis.RecruitingNCT07205614Not applicable1 country
- High-Intensity Interval Training and Menstrual Health Experience in Primary Dysmenorrhea.RecruitingNCT07391930Not applicable1 country
- Efficacy of CL25216 on Hormonal Balance and Menstrual Health in Women With Primary Dysmenorrhea.Not yet recruitingNCT07529561Not applicable1 country
- Effera Dose Response: Women's HealthRecruitingNCT07524270Not applicable1 country
- HIFU Versus Myomectomy for the Treatment of Symptomatic Uterine FibroidsRecruitingNCT06692335Not applicable1 country
- Multicenter Observational Cohort Study on the Epidemiology of Therapeutic Strategies in Patients Affected by AdenomyosisRecruitingNCT074786141 country