Ascites clinical trials
The registry lists 247 studies for Ascites across more than 10 countries. 57 are recruiting or about to start. 148 of them are mainly about Ascites (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Sequana Medical N.V. (8) · Post Graduate Institute of Medical Education and Research, Chandigarh (8) · Sanofi (7) · Assiut University (6) · Protgen Ltd (4) · Otsuka Pharmaceutical Co., Ltd. (4) · University of Michigan (4) · University of Turin, Italy (3)
What is being tested here
Drugs under test in Ascites studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Albumins | 2 | 2 | 5 |
| Atorvastatin | 1 | 1 | 2 |
| Empagliflozin | 1 | 0 | 2 |
| Carvedilol | 1 | 0 | 2 |
| Amino Acids, Branched-Chain | 1 | 1 | 2 |
| Dapagliflozin | 1 | 0 | 1 |
| Apixaban | 1 | 0 | 1 |
| Tolvaptan | 0 | 5 | 10 |
| Midodrine | 0 | 4 | 8 |
| Satavaptan | 0 | 3 | 6 |
Drug classes tested here SGLT2 inhibitors 2 open · Beta blockers 1 open · Diuretics 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jul 2027"Exploring the Potential Benefits of Using Dapagliflozin in Cirrhotic Chronic Liver Disease Patients- A Randomized Controlled Trial" · Phase 3 · Beni-Suef University
- Dec 2026Albumin Assisted Diuresis in Patients with Cirrhosis and Ascites · Anahita Rabiee MD MHS
- Dec 2026Intraperitoneal Immune Checkpoint Inhibitor for Malignant Ascites · China Medical University Hospital
- Dec 2026VICIS - Vienna Cirrhosis Study · Medical University of Vienna
- Dec 2026The Efficacy of Bevacizumab and Serplulimab Combined With Recombinant Mutant HumanTumor Necrosis Factor(rmhTNF-NC) in the Treatment of Malignant Ascites · Sun Yat-sen University
- Jan 2027Gut Leakage' in Dengue · University of Oxford
- Feb 2027Transitional Care Program for Fluid Overload in Cirrhosis · Milton S. Hershey Medical Center
- Mar 2027Statin and Beta Blocker Use in Patients With Decompensated Cirrhosis · CAMC Health System
- Mar 2027High Dose Albumin in Refractory Ascites · Baylor College of Medicine
- Apr 2027QOL and Sarcopenia in Patients With Ascites · Abramson Cancer Center at Penn Medicine
Who these studies take
Of the 41 Ascites studies recruiting now, 21 (51%) set no upper age limit and 13 (32%) stop at 75 or younger. 1 (2%) take children under 18. 3 (7%) are for women only and 0 (0%) for men only; 2 (5%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (2%) | 1 (2%) |
| 18 | 39 (95%) | 36 (88%) |
| 30 | 40 (98%) | 37 (90%) |
| 40 | 40 (98%) | 37 (90%) |
| 50 | 40 (98%) | 37 (90%) |
| 65 | 40 (98%) | 37 (90%) |
| 75 | 36 (88%) | 33 (80%) |
| 85 | 24 (59%) | 21 (51%) |
Across all 247 studies, recruiting or not: 33% stop at 75 or younger and 9% at 65; 8% take children; 5% are for women only and 1% for men only; 5% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Ascites studies take
Of 13 phase 3 interventional studies under Ascites, half reached primary completion within 28 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 28 mo16–49 · 13 studies | — | — |
| Interventional, no phase | 32 mo21–62 · 33 studies | — | — |
| Observational | 50 mo20–… · 28 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Newly registered3
- Optimal Treatment Strategy for Spontaneous Bacterial PeritonitisNov 6, 2026NCT07923318
- Low Dose Versus Standard Dose AlbuminNov 5, 2026NCT07917819
- Development and Validation of a TIPS Prognostic ModelNov 2, 2026NCT07909850
Studies
Recruiting first, then most recently updated. Showing 50 of 247. Browse all 247 → or search them.
- VIATORR® TIPS Study Evaluating 6-10mm Diameters (VIATIPS)RecruitingNCT073903442 countries
- Optimal Treatment Strategy for Spontaneous Bacterial PeritonitisRecruitingNCT07923318Not applicable1 country
- Low Dose Versus Standard Dose AlbuminEnrolling by invitationNCT07917819Phase 41 country
- High Dose Albumin in Refractory AscitesRecruitingNCT05867602Phase 21 country
- Development and Validation of a TIPS Prognostic ModelNot yet recruitingNCT07909850
- Anti-PD-1 in Combination With Systemic Chemotherapy With Nab-paclitaxel Intraperitoneal Infusion for Untreated Advanced Gastric Cancer With Malignant AscitesRecruitingNCT078556401 country
- Prospective Laboratory Study Biologic Specimens and Tumor Tissue of Patients With CancerRecruitingNCT039433161 country
- At-Home Paracentesis for Cancer-Related Malignant Ascites (Paracentesis)RecruitingNCT07490626Not applicable1 country
- A Clinical Trial With Apatinib for Subjects With Refractory Malignant AscitesRecruitingNCT03020979Phase 21 country
- Proximal Splenic Artery Embolization (PSAE) for the Treatment of Refractory Ascites in Decompensated CirrhosisNot yet recruitingNCT07755059Not applicable1 country
- Gut Leakage' in DengueRecruitingNCT076029201 country
- Role of Nutritional Intervention for the Treatment of Sarcopenia in Cirrhotic Patients With Refractory Ascites Candidate to Transjugular Intrahepatic Portosystemic Shunt Placement and Identification of Prognostic Factors Related to Clinical OutcomeRecruitingNCT06814626Phase 32 countries
- "Exploring the Potential Benefits of Using Dapagliflozin in Cirrhotic Chronic Liver Disease Patients- A Randomized Controlled Trial"RecruitingNCT07684326Phase 2/31 country
- Ultrasound Assessment of Diaphragmatic Structure and Function in Patients With Liver Cirrhosis: A Point-of-Care Tool for Predicting Complications and Sarcopenia in Limited Resource SettingsNot yet recruitingNCT07667608
- QOL and Sarcopenia in Patients With AscitesRecruitingNCT057267471 country
- Personalized Nutritional Intervention in Patients Undergoing TIPS Insertion for Refractory Ascites to Prevent Overt Hepatic EncephalopathyNot yet recruitingNCT07634237Not applicable1 country
- DICE Study- Diastolic Improvement With Carvedilol & Empagliflozin in Patients With CirrhosisRecruitingNCT07322237Phase 41 country
- Early TIPS in Patients With Liver Cirrhosis and AscitesRecruitingNCT06576934Not applicable1 country
- Apixaban-PK Trial: Preventing Portal Hypertension Complications in CirrhosisRecruitingNCT07521332Phase 41 country
- Intraperitoneal SK-NK Cell Injection for Advanced Ovarian Cancer With Massive AscitesRecruitingNCT07435701Phase 1/21 country
- Fiber-Optic Navigation During TIPS Creation: A Prospective Pilot StudyNot yet recruitingNCT07470515Not applicable1 country
- Transitional Care Program for Fluid Overload in CirrhosisRecruitingNCT06174272Not applicable1 country
- Statin and Beta Blocker Use in Patients With Decompensated CirrhosisRecruitingNCT06764966Phase 21 country
- Intraperitoneal Injection of Liposomal Irinotecan as Monotherapy or in Combination With Recombinant Mutant Human Tumor Necrosis Factor or Bevacizumab for the Treatment of Malignant Ascites Following Failure of Prior Standard TherapyRecruitingNCT07397819Phase 1/21 country
- Personalized Long-term Human Albumin Treatment in Patients With Decompensated Cirrhosis and AscitesRecruitingNCT05056220Phase 37 countries
- Effectiveness and Safety of TIPS Stent Graft in the Treatment of Cirrhosis and Complications of Portal HypertensionRecruitingNCT06669806Not applicable1 country
- Pediatric Intravenous Contrast-Enhanced Ultrasound(CEUS) in ChinaRecruitingNCT071138081 country
- Intraperitoneal Immune Checkpoint Inhibitors and Zoledronic Acids for Gastric Cancer Malignant AscitesRecruitingNCT06759064Phase 1/21 country
- Ultrasound and AscitesNot yet recruitingNCT07196553
- Oral Branched-chain Amino Acid Supplementation for Decompensated Cirrhotic PatientsEnrolling by invitationNCT06121479Phase 31 country
- VICIS - Vienna Cirrhosis StudyRecruitingNCT032676151 country
- TIPS in Patients With Decompensated Liver CirrhosisRecruitingNCT048012901 country
- Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver CirrhoticsRecruitingNCT05490888Phase 11 country
- Prediction of SBP in Cirrhotic Patients by Platlet Count, Na and AlBl Index.Not yet recruitingNCT071163691 country
- A Phase I Study of SIM0388 in Participants With Malignant Ascites.RecruitingNCT07007988Phase 11 country
- Application of Bacterial DNA Quantitative Detection in Diagnosis of SBP in Cirrhosis: A Multi Center Diagnostic ExperimentEnrolling by invitationNCT069958461 country
- SK-NK Injection in Patients With Advanced Solid Tumors Accompanied by Malignant AscitesNot yet recruitingNCT06991478Phase 1/2
- Clinical Study to Evaluate the Efficacy and Safety of Dapagliflozin in Patients With Refractory Cirrhotic AscitesNot yet recruitingNCT06919523Phase 2
- Medical-economic Evaluation of the Care of Refractory Ascites by Implantation of Alfapump® Device in Cirrhotic PatientsRecruitingNCT03506893Not applicable1 country
- Albumin Assisted Diuresis in Patients with Cirrhosis and AscitesRecruitingNCT06812390Phase 21 country
- Faecal Microbiota Transplantation for Liver CirrhosisRecruitingNCT04932577Phase 2/31 country
- Drug Sensitivity of Hydrothorax and Ascite Organoids from Breast CancerRecruitingNCT066580801 country
- High Definition Profiling of Ovarian Cancer AscitesNot yet recruitingNCT065537421 country
- HRS-AKI Treatment With TIPS in Patients With CirrhosisRecruitingNCT05346393Not applicable1 country
- Austrian Registry on Transjugular Intrahepatic Portosystemic ShuntsRecruitingNCT034092631 country
- 13C-Glucose Tracing of Tumour and T Cells in the Ascites of Ovarian Cancer Patients.RecruitingNCT050258781 country
- The Efficacy of Bevacizumab and Serplulimab Combined With Recombinant Mutant HumanTumor Necrosis Factor(rmhTNF-NC) in the Treatment of Malignant AscitesRecruitingNCT06433869Phase 21 country
- ASSESSMENT OF SURGICAL RISK IN PATIENTS WITH CHRONIC LIVER DISEASE USING VOCAL PENN SCORERecruitingNCT062279881 country
- A Clinical Study of Intraperitoneal T3011 Given as a Single Agent in Patients With Malignant Ascites Induced by Advanced Colorectal CancerRecruitingNCT06200376Phase 11 country
- Clinical Validation of Programmable Drain Fluid Regulator to Reduce Morbidity, Care Requirements, and Improve OutcomesRecruitingNCT05734729Not applicable1 country