Quadriplegia clinical trials
The registry lists 222 studies for Quadriplegia across more than 10 countries. 75 are recruiting or about to start. 83 of them are mainly about Quadriplegia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Locked-In Syndrome too: 236 studies, 83 open.
Get an email when these change. Save the Quadriplegia studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
VA Office of Research and Development (9) · James J. Peters Veterans Affairs Medical Center (7) · Neuralink Corp (7) · Wandercraft (6) · Washington University School of Medicine (5) · Assistance Publique - Hôpitaux de Paris (5) · Shepherd Center, Atlanta GA (4) · Leigh R. Hochberg, MD, PhD. (4)
What is being tested here
Drugs under test in Quadriplegia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Bronchodilators 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jul 2027A Trial Investigating the Efficacy and Safety of NVG-291 in Subjects With Chronic Spinal Cord Injury · Phase 3 · NervGen Pharma
- Aug 2027Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI) · Phase 3 · Northwell Health
- Nov 2026Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord Injury · Istanbul Physical Medicine Rehabilitation Training and Research Hospital
- Nov 2026Transspinal Stimulation With and Without Blood Flow Restricted Exercise Via Telehealth in Persons With Tetraplegia · Virginia Commonwealth University
- Nov 2026UAE-PRIME: A Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External Devices · Neuralink Corp
- Dec 2026Home-Based Digital Rehabilitation Program Optimized With Transcutaneous Spinal Cord Stimulation for Upper Limb Functional Enhancement in Tetraplegia (HOPE): A Safety, Efficacy, and Feasibility Study · Singapore General Hospital
- Dec 2026Development and Validation of a New Questionnaire for Caregivers to Assess Hip Pain in Quadriplegic Pediatric Patients: Non-Ambulatory Hip Pain Questionnaire · Azienda USL Reggio Emilia - IRCCS
- Dec 2026Virtual Peer Coaching in Manual Wheelchair Skills · University of Pittsburgh
- Dec 2026Acute Genital Nerve Stimulation for Neurogenic Bowel Dysfunction in Individuals Living With Spinal Cord Injury · MetroHealth Medical Center
- Dec 2026Brain Controlled Spinal Cord Stimulation in Participants With Cervical Spinal Cord Injury for Upper Limb Rehabilitation · Ecole Polytechnique Fédérale de Lausanne
Who these studies take
Of the 57 Quadriplegia studies recruiting now, 17 (30%) set no upper age limit and 28 (49%) stop at 75 or younger. 2 (4%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (2%) | 1 (2%) |
| 18 | 41 (72%) | 41 (72%) |
| 30 | 56 (98%) | 56 (98%) |
| 40 | 56 (98%) | 56 (98%) |
| 50 | 56 (98%) | 56 (98%) |
| 65 | 54 (95%) | 54 (95%) |
| 75 | 38 (67%) | 38 (67%) |
| 85 | 17 (30%) | 17 (30%) |
Across all 222 studies, recruiting or not: 55% stop at 75 or younger and 35% at 65; 15% take children; 0% are for women only and 2% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Quadriplegia studies take
Of 97 interventional studies with no phase under Quadriplegia, half reached primary completion within 41 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 41 mo15–309 · 97 studies | — | 57 mo16–309 · 77 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord InjuryNov 3, 2026NCT07846410
Newly registered3
- An Early Feasibility Study of a Robotically Implanted Brain-Computer Interface for Neural Control of External Devices in Spinal Cord Injury, Amyotrophic Lateral Sclerosis, and Chronic Ischemic StrokeNov 10, 2026NCT07929792
- Focused Versus Radial Extracorporeal Shock Wave Therapy on Gastrocnemius Spasticity in Children With Spastic Quadriplegic Cerebral PalsyOct 26, 2026NCT07894003
- Evaluation of a Voice-Activated Call Light System for Clients With Limited Upper-Extremity MobilityOct 14, 2026NCT07873151
Studies
Recruiting first, then most recently updated. Showing 50 of 222. Browse all 222 → or search them.
- An Early Feasibility Study of a Robotically Implanted Brain-Computer Interface for Neural Control of External Devices in Spinal Cord Injury, Amyotrophic Lateral Sclerosis, and Chronic Ischemic StrokeRecruitingNCT07929792Not applicable1 country
- VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication RestorationRecruitingNCT07224256Not applicable1 country
- MyHand-SCI: An Active Hand Orthosis for Spinal Cord InjuryRecruitingNCT05553457Not applicable1 country
- A Trial Investigating the Efficacy and Safety of NVG-291 in Subjects With Chronic Spinal Cord InjuryRecruitingNCT07799532Phase 32 countries
- Transcutaneous Tibial Nerve Stimulation in Acute Spinal Cord InjuryRecruitingNCT03965299Not applicable1 country
- Acute Genital Nerve Stimulation for Neurogenic Bowel Dysfunction in Individuals Living With Spinal Cord InjuryRecruitingNCT05626816Not applicable1 country
- Pilot Study of Galantamine to Treat Metabolic Syndrome in People With Chronic Traumatic Spinal Cord Injury (SCI)RecruitingNCT07625332Phase 2/31 country
- At-Home Genital Nerve Stimulation for SCI BowelRecruitingNCT06836739Not applicable1 country
- Virtual Reality-Based Hypnotherapy for Pain, Sleep, and Mood in Spinal Cord InjuryRecruitingNCT07846410Not applicable1 country
- MindEx: A Novel, Multifocal, Cognitive Brain-Machine Interface SystemRecruitingNCT05936619Not applicable1 country
- Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)RecruitingNCT06511934Not applicable1 country
- A Neuroprosthesis for Seated Posture and BalanceRecruitingNCT01474148Not applicable1 country
- Transspinal Stimulation With and Without Blood Flow Restricted Exercise Via Telehealth in Persons With TetraplegiaRecruitingNCT05423600Not applicable1 country
- Augmenting Upper Limb Function and Functional Neuroplasticity Using Epidural Stimulation of the Cervical Spinal CordRecruitingNCT06225245Not applicable1 country
- Evaluation of a Voice-Activated Call Light System for Clients With Limited Upper-Extremity MobilityEnrolling by invitationNCT078731511 country
- Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)RecruitingNCT07521930Not applicable1 country
- Efficacy of Robotic Upper Limb Rehabilitation Training in Patients With TetraplegiaRecruitingNCT07860827Not applicable1 country
- Implantable Wireless Brain-Computer Interface Systems in Patients With TetraplegiaRecruitingNCT07784088Not applicable1 country
- Investigation on the Cortical Communication (CortiCom) SystemRecruitingNCT03567213Not applicable1 country
- Investigation on the Bidirectional Cortical Neuroprosthetic SystemRecruitingNCT03161067Not applicable1 country
- An Early Feasibility Study of the ReHAB SystemRecruitingNCT03898804Not applicable1 country
- Psilocybin to Treat Depression in Spinal Cord InjuryRecruitingNCT07251491Phase 1/21 country
- Upper Limb Rehabilitation Using Non-invasive Spinal Cord StimulationNot yet recruitingNCT07361627Not applicable1 country
- Evaluation of an Advanced Lower Extremity NeuroprosthesesRecruitingNCT00623389Not applicable1 country
- Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord InjuryRecruitingNCT05321017Not applicable1 country
- Spinal Cord Associative Plasticity StudyRecruitingNCT05163639Early Phase 11 country
- Innovative Brain-Computer Interface for People With Spinal Cord InjuryRecruitingNCT07640711Not applicable1 country
- Abdominal Stimulation to Improve Cough After Spinal Cord InjuryNot yet recruitingNCT07626931Not applicable
- Feasibility of the BrainGate2 Neural Interface System in Persons With TetraplegiaRecruitingNCT05724173Not applicable1 country
- BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With TetraplegiaRecruitingNCT00912041Not applicable1 country
- Cortical Recording and Stimulating Array Brain-Machine InterfaceRecruitingNCT01894802Not applicable1 country
- Combined rTMS and tSCS for Upper Limb Recovery in Cervical SCINot yet recruitingNCT07586644Not applicable1 country
- Immediate Effects On Gait and Spasticity After The Use Of Passive Kinesiotherapy Equipment In The Lower Limbs Of Neurological PatientsEnrolling by invitationNCT06696040Not applicable1 country
- Evaluation of Brain MRI Changes in Cerebral Palsy PatientsRecruitingNCT074336471 country
- Development and Validation of a New Questionnaire for Caregivers to Assess Hip Pain in Quadriplegic Pediatric Patients: Non-Ambulatory Hip Pain QuestionnaireRecruitingNCT06798233Not applicable1 country
- Brain Controlled Spinal Cord Stimulation in Participants With Cervical Spinal Cord Injury for Upper Limb RehabilitationRecruitingNCT05665998Not applicable1 country
- Self-balancing Personal Exoskeleton for SCI (WIP)RecruitingNCT07536386Not applicable1 country
- Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)RecruitingNCT07357428Not applicable1 country
- Virtual Peer Coaching in Manual Wheelchair SkillsRecruitingNCT06295146Not applicable1 country
- MEP Up-conditioning to Target Corticospinal PlasticityRecruitingNCT06989905Early Phase 11 country
- Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)Enrolling by invitationNCT072641661 country
- Visuomotor Prosthetic for ParalysisRecruitingNCT01958086Not applicable1 country
- Nerve Transfer to Improve Function in High Level TetraplegiaRecruitingNCT062887632 countries
- Restoring Motor and Sensory Hand Function in Tetraplegia Using a Neural Bypass SystemRecruitingNCT03680872Not applicable1 country
- Home-Based Digital Rehabilitation Program Optimized With Transcutaneous Spinal Cord Stimulation for Upper Limb Functional Enhancement in Tetraplegia (HOPE): A Safety, Efficacy, and Feasibility StudyNot yet recruitingNCT07438353Not applicable1 country
- SCI Epidemiology and ComplicationsNot yet recruitingNCT074254701 country
- Development of Optimal Sensory Feedback Strategies to Maximize Function After TetraplegiaRecruitingNCT07225582Not applicable1 country
- A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord InjuryRecruitingNCT06841770Phase 11 country
- Self-balancing Personal Exoskeleton for SCI (WINY)RecruitingNCT07222033Not applicable1 country
- Precise Robotically IMplanted Brain-Computer InterfacERecruitingNCT06429735Not applicable1 country