Syncope, Vasovagal clinical trials
The registry lists 88 studies for Syncope, Vasovagal across more than 10 countries. 28 are recruiting or about to start. 62 of them are mainly about Syncope, Vasovagal (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-14.
Get an email when these change. Save the Syncope, Vasovagal studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Who runs them
National Institute of Neurological Disorders and Stroke (NINDS) (7) · Istituto Auxologico Italiano (6) · University of Calgary (6) · Centre of Postgraduate Medical Education (5) · Abbott Medical Devices (3) · Boston Scientific Corporation (3) · Simon Fraser University (3) · New York Medical College (3)
What is being tested here
Drugs under test in Syncope, Vasovagal studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Atomoxetine | 1 | 1 | 2 |
| Ondansetron | 1 | 0 | 1 |
| Midodrine | 0 | 1 | 2 |
| Metoprolol | 0 | 0 | 2 |
| Fludrocortisone acetate | 0 | 1 | 2 |
| Fludrocortisone | 0 | 1 | 2 |
| Propranolol | 0 | 0 | 2 |
| Phenylephrine | 0 | 0 | 1 |
| Omega-N-Methylarginine | 0 | 0 | 1 |
| Lidocaine | 0 | 0 | 1 |
Drug classes tested here Beta blockers 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Cardioneuroablation for Reflex Syncope and Exercise Capacity · Centre of Postgraduate Medical Education
- Nov 2026Cardioinhibitory Reflex Syncope. Permanent Pacemaker Therapy or Cardioneuroablation? · Institut d'Investigació Biomèdica de Bellvitge
- Dec 2026Total Underwater Colonoscopy (TUC) for Improved Colorectal Cancer Screening: A Randomized Controlled Trial · Vestre Viken Hospital Trust
- Dec 2026Impact of Blood Phobia on Fainting Susceptibility · Simon Fraser University
- Dec 2026Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry · Rush University Medical Center
- Jan 2027Assessment of Stroke Volume and Cardiac Output in Response to Varying Heart Rates · University of Calgary
- Apr 2027The Effect of Water Carbonation on Orthostatic Tolerance · Simon Fraser University
- May 2027Postural Sway and Counterpressure Maneuvers for Pediatric Syncope · Simon Fraser University
- Jun 2027Assesment of the Clinical Benefit of Provocation on Tilt-table in SYNCope Patients, TiltSYNC-trial · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- Sep 2027Paediatric Syncope in the Emergency Department · Dr. Victoria Claydon
Who these studies take
Of the 24 Syncope, Vasovagal studies recruiting now, 13 (54%) set no upper age limit and 8 (33%) stop at 75 or younger. 6 (25%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (8%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (13%) | 3 (13%) |
| 18 | 21 (88%) | 21 (88%) |
| 30 | 20 (83%) | 20 (83%) |
| 40 | 21 (88%) | 21 (88%) |
| 50 | 21 (88%) | 21 (88%) |
| 65 | 17 (71%) | 17 (71%) |
| 75 | 16 (67%) | 16 (67%) |
| 85 | 15 (63%) | 15 (63%) |
Across all 88 studies, recruiting or not: 32% stop at 75 or younger and 27% at 65; 32% take children; 2% are for women only and 1% for men only; 23% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Syncope, Vasovagal studies take
Of 29 interventional studies with no phase under Syncope, Vasovagal, half reached primary completion within 39 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 39 mo15–… · 29 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 88. Browse all 88 → or search them.
- Fainting Detection And Early Warning In Syncope Evaluation Study (ARISE)RecruitingNCT075025991 country
- Total Underwater Colonoscopy (TUC) for Improved Colorectal Cancer Screening: A Randomized Controlled TrialRecruitingNCT06333392Not applicable2 countries
- Comparison of Focal Cryoablation vs. Radiofrequency Cardioneuroablation for BradyarrhythmiasRecruitingNCT07671898Not applicable1 country
- Aveir DR Real-World Evidence Post-Approval StudyRecruitingNCT059350071 country
- Assessment of Stroke Volume and Cardiac Output in Response to Varying Heart RatesRecruitingNCT03446326Not applicable1 country
- Postural Sway and Counterpressure Maneuvers for Pediatric SyncopeRecruitingNCT05633693Not applicable1 country
- The Effect of Water Carbonation on Orthostatic ToleranceRecruitingNCT05621460Not applicable1 country
- Paediatric Syncope in the Emergency DepartmentRecruitingNCT05555771Not applicable1 country
- Assesment of the Clinical Benefit of Provocation on Tilt-table in SYNCope Patients, TiltSYNC-trialRecruitingNCT07459478Not applicable1 country
- Cardioneuroablation: Fragmented Atrial Potentials, Intracardiac Echocardiography and Computed TomographyRecruitingNCT06472102Not applicable1 country
- Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD RegistryRecruitingNCT061662771 country
- Implantable Loop Recorder and CardioneuroblationNot yet recruitingNCT071627401 country
- National Registry of Cardioneuroablation in Recurrent Reflex SyncopeRecruitingNCT061597641 country
- Impact of Blood Phobia on Fainting SusceptibilityRecruitingNCT06336031Not applicable1 country
- Cardioneuroablation and Ventricular ProarrhythmiaRecruitingNCT06458140Not applicable1 country
- Efficacy of a Right-sided Ablation of the Anterior Ganglionated Plexus for Neurally Mediated SyncopeRecruitingNCT04755101Not applicable1 country
- AVEIR™ Leadless Pacemaker Registry in Europe and MIddle East Region (PREMIER LEADLESS)Not yet recruitingNCT06782152
- Clinical Association Between Obstructive Sleep Apnea, Facial Pigmentation, and Vasovagal Symptoms.RecruitingNCT063318191 country
- Mechanism-based Therapy of Hypotensive SyncopeRecruitingNCT065136505 countries
- A Proof of Principle Study of Ondansetron for the Prevention of Vasovagal Syncope: The Eleventh Prevention of Syncope Trial (POST11)RecruitingNCT05755737Phase 21 country
- Study of Atomoxetine in the Prevention of Vasovagal SyncopeRecruitingNCT05159687Phase 31 country
- Syncope-Asystole Latency Time in Tilt Table Test: The SALT-TILT StudyRecruitingNCT063562071 country
- Treatment Strategy of Vasovagal SyncopeRecruitingNCT05803148Not applicable1 country
- Cardioinhibitory Reflex Syncope. Permanent Pacemaker Therapy or Cardioneuroablation?RecruitingNCT05855603Not applicable1 country
- Prevention of Vasovagal Reactions in First-time Blood Donors Using a Combined PSYchological and Physiological ApproachNot yet recruitingNCT06014346Not applicable1 country
- Essential Hypotension and Allostasis RegistryRecruitingNCT020184971 country
- Cardiac Autonomic Denervation for Cardio-inhibitory SyncopeNot yet recruitingNCT05572034Not applicable1 country
- Cardioneuroablation in Reflex Syncope (CARDIOSYRE Trial)RecruitingNCT05513755Not applicable1 country
- Cardioneuroablation for Reflex Syncope and Exercise CapacityActive, not recruitingNCT06440291Not applicable1 country
- A Warning Red Flag Classification System to Predict Risk of Vasovagal Event During Office HysteroscopyActive, not recruitingNCT070302181 country
- Aveir DR i2i StudyCompletedNCT05252702Not applicable13 countries
- Aveir VR Real-World Evidence Post-Approval StudyActive, not recruitingNCT052704991 country
- Mechanisms of Vasovagal SyncopeCompletedNCT01791816Early Phase 11 country
- Northera Improves Postural Tachycardia Syndrome (POTS) and Postural Vasovagal Syncope (VVS)TerminatedNCT02558972Phase 21 country
- Cardioneuroablation: Comparison of Right Versus Left Atrial Approach in Patients With Reflex SyncopeTerminatedNCT05225532Not applicable1 country
- BAsel Syncope EvaLuation (BASEL IX) StudyActive, not recruitingNCT015483529 countries
- Assessment of the Durability of Cardioneuroablation Using Physiological Indices of Heart Rate ReactivityCompletedNCT06697145Not applicable1 country
- Head-up Tilt Test in Patients With Reflex Syncope and Asystolic Response Who Received a Dual-chamber Pacemaker With the Closed Loop Stimulation (CLS) and Participated in the BIOSync TrialCompletedNCT060387081 country
- Heart Rate Variation in Females Predicts Tilt Test ResultsActive, not recruitingNCT064960741 country
- The Effect of CPC on Aborting Tilt Induced Syncope in Patients With a History of Vasovagal Syncope or Near SyncopeCompletedNCT04972123Phase 21 country
- Assessment of the Mechanism of Non-cardiac SyncopeCompletedNCT057282555 countries
- VINCI-AD: An Investigation of Transcutaneous Vagus Nerve Stimulation in Mild Cognitive Impairment.CompletedNCT05514756Not applicable1 country
- Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging SubjectsActive, not recruitingNCT02123056Phase 41 country
- Assessment of Midodrine in the Prevention of Vasovagal Syncope: The Prevention of Syncope Trial IVActive, not recruitingNCT01456481Phase 43 countries
- Effect of Pharmacological Interventions on Systolic Blood Pressure Drops (SynABPM 2 Proof-of-concept)CompletedNCT057297241 country
- Wearable Monitor in Patients With SyncopeCompletedNCT05782647Not applicable1 country
- Different Catheter Ablation Strategy in Vasovagal SyncopeCompletedNCT05573178Not applicable1 country
- Presyncope (Syncope) Prevention StudyCompletedNCT04772755Not applicable1 country
- Data Collection - Of Syncope Tilt Table Testing StudyCompletedNCT037213931 country
- Detecting Syncope by an Integrated Multisensor Patch-type RecorderCompletedNCT05782699Not applicable1 country