Autonomic Dysreflexia clinical trials

The registry lists 30 studies for Autonomic Dysreflexia across 5 countries. 10 are recruiting or about to start. 17 of them are mainly about Autonomic Dysreflexia (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-29.

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Status

Completed: 16
Recruiting: 6
Status unknown: 4
Not yet recruiting: 3
Enrolling by invitation: 1

Phase

Phase 2: 4
Phase 4: 3
Phase 3: 1
Early Phase 1: 1

Where

United States: 16
Canada: 10
Czechia: 1
Switzerland: 1
Korea, Republic of: 1

Who runs them

James J. Peters Veterans Affairs Medical Center (6) · University of British Columbia (6) · University of Louisville (2) · Simon Fraser University (2) · Mayo Clinic (2) · University of Washington (1) · Rick Hansen Institute (1) · VA Office of Research and Development (1)

What is being tested here

Drugs under test in Autonomic Dysreflexia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Open	Phase 3	All
Botulinum toxin type A	1	0	2
Midodrine	0	1	2
Pyridostigmine	0	0	1
Mirabegron	0	0	1
Onabotulinum toxin A	0	0	1
Fesoterodine	0	0	1
Prazosin	0	0	1
Mecamylamine	0	0	1

Coming up

0phase 3 studies under way

2studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 2

Dec 2026Deciphering Preserved Autonomic Function After Multiple Sclerosis · Mayo Clinic
Oct 2027Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Individuals With Spinal Cord Injuries · VA Office of Research and Development

Who these studies take

Of the 6 Autonomic Dysreflexia studies recruiting now, 3 (50%) set no upper age limit and 3 (50%) stop at 75 or younger. 1 (17%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (17%) take healthy volunteers.

Recruiting studies that take each age, of 6
Age	Women	Men
10	1 (17%)	1 (17%)
18	5 (83%)	5 (83%)
30	6 (100%)	6 (100%)
40	6 (100%)	6 (100%)
50	6 (100%)	6 (100%)
65	3 (50%)	3 (50%)
75	3 (50%)	3 (50%)
85	3 (50%)	3 (50%)

Across all 30 studies, recruiting or not: 67% stop at 75 or younger and 47% at 65; 7% take children; 0% are for women only and 3% for men only; 30% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

What changed recently

From the registry's own updates since Oct 13, 2026.

Results posted1

Recovery of Bladder and Sexual Function After Human Spinal Cord InjuryOct 29, 2026NCT04193709

Studies

Recruiting first, then most recently updated. Showing 30 of 30. search them.