Lamotrigine: all 139 studies that test it

Page 1 of 2. Open to participants first (3), then studies with results posted, then the rest; newest registration first within each.

• Effect of Adding Lamotrigine to Sodium Valproate in Childhood Epilepsy: Clinicolabratory StudyNot yet recruitingNCT05881928Phase 4
• The Efficacy and Safety of Lamotrigine Versus Carbamazepine in Focal EpilepsyEnrolling by invitationNCT05748236Phase 4
• Modification of Epilepsy Screen Questionnaire and Treatment Feasibility EvaluationNot yet recruitingNCT04939675Not applicable
• Enhancing the Effects of Alcohol Treatment With LamotrigineCompletedNCT04770493Phase 2Results posted
• A Study in Healthy Men to Test Whether BI 409306, BI 425809 or Lamotrigine Can Reverse the Memory Problems Caused by KetamineCompletedNCT04602221Phase 1Results posted
• Lamotrigine in Reducing Psychologic Side-Effect of Perioperative KetamineCompletedNCT03831854Phase 3Results posted
• Low vs. Standard Daily Doses of Antiepileptic Drugs in Newly Diagnosed, Previously Untreated Epilepsy(STANDLOW)CompletedNCT03689114Phase 4Results posted
• Melancholic Symptoms in Bipolar Depression and Responsiveness to LamotrigineCompletedNCT02989727Phase 4Results posted
• A Bioavailability Crossover Study of Two Formulations of Lamotrigine Extended Release Tablets in Healthy SubjectsCompletedNCT02821338Phase 1Results posted
• Characterization of Epilepsy Patients BEEP 2bCompletedNCT02707965Phase 1Results posted
• BEEP Follow Up: Evaluation of Repeatability of Lamotrigine Pharmacokinetics in Epileptic PatientsCompletedNCT02404168Phase 4Results posted
• 16-week Comparative Effectiveness Trial of Lamotrigine vs. Fluoxetine for Bipolar DepressionTerminatedNCT02389712Phase 4Results posted
• Study of Lamotrigine to Treat Ménière's DiseaseCompletedNCT02158585Phase 2Results posted
• Lamotrigine BioequivalenceCompletedNCT01995825Phase 4Results posted
• Cognitive AED Outcomes in Pediatric Localization Related Epilepsy (COPE)TerminatedNCT01891890Phase 3Results posted
• PET and MRI Brain Imaging of Bipolar DisorderCompletedNCT01880957Not applicableResults posted
• Lamotrigine Phase III Study in Bipolar I DisorderCompletedNCT01602510Phase 3Results posted
• Sequential Multiple Assignment Treatment for Bipolar DisorderCompletedNCT01588457Phase 4Results posted
• Decision-Making in Bipolar DisorderCompletedNCT01463111Not applicableResults posted
• Clinical Study of Lamotrigine to Treat Newly Diagnosed Typical Absence Seizure in Children and AdolescentsCompletedNCT01431976Phase 3Results posted
• Clinical Study of Lamotrigine to Treat Newly Diagnosed EpilepsyCompletedNCT01431963Phase 3Results posted
• Reversing Corticosteroid Induced Memory ImpairmentCompletedNCT01142310Phase 4Results posted
• Bipolar Depression Before and After Lamotrigine TreatmentCompletedNCT01042496Phase 3Results posted
• Treatment of Alcohol Dependence and Comorbid Bipolar DisorderCompletedNCT01015586Phase 4Results posted
• Cognitive Effects of Treatment of Interictal DischargesCompletedNCT00916149Not applicableResults posted
• Lamotrigine 25 mg Chewable Tablets, FastingCompletedNCT00838279Phase 1Results posted
• Lamotrigine 25 mg Chewable Tablets, Non-FastingCompletedNCT00838136Phase 1Results posted
• Bioequivalence Study of 200 mg Lamotrigine Tablet Under Non-Fasting ConditionsCompletedNCT00835263Phase 1Results posted
• Bioequivalence Study of 200 mg Lamotrigine Tablet Under Fasting ConditionsCompletedNCT00834561Phase 1Results posted
• The Efficacy and Safety of Low Dose Combination of LTG and VPA Compared to CBZ MonotherapyCompletedNCT00807989Phase 4Results posted
• Lamictal as Add-on Treatment for Bipolar I Disorder in Pediatric PatientsCompletedNCT00723450Phase 3Results posted
• Lamotrigine Therapy in Geriatric Bipolar DepressionCompletedNCT00720473Not applicableResults posted
• Lamotrigine for Symptoms of Geriatric Bipolar DepressionCompletedNCT00621842Phase 3Results posted
• An Open-Label Trial Measuring Satisfaction And Convenience Of Two Formulations Of Lamotrigine In Subjects With A Mood DisorderCompletedNCT00579982Phase 3Results posted
• A Clinical Evaluation Of BW430C (Lamotrigine) In Bipolar I Disorder- Long-term Extension Of Study SCA104779 (NCT00550407) -CompletedNCT00566020Phase 3Results posted
• An Evaluation Of BW430C (Lamotrigine) Versus Placebo In The Prevention Of Mood Episodes In Bipolar I Disorder PatientsCompletedNCT00550407Phase 3Results posted
• Early Detection and Intervention for the Prevention of PsychosisCompletedNCT00531518Not applicableResults posted
• Lamotrigine Extended-Release In Elderly Patients With EpilepsyCompletedNCT00516139Phase 3Results posted
• Double-Blind Lamictal (Lamotrigine) in Neurotic ExcoriationCompletedNCT00513019Phase 2Results posted
• Study on the Treatment of Elderly Patients With Older and Newer Antiepileptic DrugsCompletedNCT00438451Phase 4Results posted
• Clinical Evaluation of BW430C in EpilepsyCompletedNCT00395694Phase 3Results posted
• An Open-Label Extension Study Of Lamotrigine In Subjects With Bipolar DisorderCompletedNCT00360126Phase 4Results posted
• Conversion To Monotherapy With Lamictal Extended Release Tablets For Treatment Of Partial EpilepsyCompletedNCT00355082Phase 3Results posted
• A Study for Evaluating the Efficacy and Safety of Zonisamide and Lamotrigine (Lamictal) for Subjects With Refractory Simple Partial, Complex Partial or Partial With Secondary Generalized SeizuresCompletedNCT00292461Phase 3Results posted
• Lamotrigine add-on Therapy for Bipolar Disorder and Cocaine DependencyCompletedNCT00280293Phase 4Results posted
• A Phase IV Study of the Safety and Efficacy of Aripiprazole in Combination With Lamotrigine in the Long-Term Maintenance Treatment of Patients With Bipolar I Disorder With A Recent Manic or Mixed EpisodeCompletedNCT00277212Phase 4Results posted
• Evaluation of Lamotrigine on Neuropathic Facial Pain Using fMRICompletedNCT00243152Not applicableResults posted
• Clinical Trial of Lamotrigine to Reverse Cognitive Impairment in Chronic Corticosteroid-Treated PatientsCompletedNCT00223262Phase 4Results posted
• Research Study to Test Safety and Effectiveness of Investigational Drug in Patients With Trigeminal NeuralgiaCompletedNCT00203229Not applicableResults posted
• Lamotrigine for the Treatment of Mania in Youth Ages 6-17 With Bipolar DisorderCompletedNCT00181844Phase 4Results posted
• Lamotrigine Monotherapy in Pediatric Bipolar DisorderCompletedNCT00176228Phase 2Results posted
• Study Evaluating LAMICTAL Extended-Release Therapy Added To Current Seizure Treatments In Patients With Primary Generalized Tonic-Clonic Seizures (PGTC) SeizuresCompletedNCT00104416Phase 3Results posted
• Childhood Absence Epilepsy Rx PK-PD-Pharmacogenetics StudyCompletedNCT00088452Phase 3Results posted
• Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With CancerCompletedNCT00068445Phase 3Results posted
• Combination Therapy for the Treatment of Bipolar DisordersTerminatedNCT00063362Phase 3Results posted
• A Study to Evaluate the Effects of Lithium, Valproic Acid, and Lamotrigine on the Pharmacokinetics of KarXT and Effects of KarXT on the Pharmacokinetics of Lithium, Valproic Acid, and Lamotrigine in Healthy ParticipantsCompletedNCT06729970Phase 1
• Single-dose, Two-way Crossover Bioequivalence of Lamotrigine in Healthy Male Volunteers Under Fasting ConditionsCompletedNCT06199791Phase 1
• Treatment of Myotonia - Lamotrigine Versus NamusclaStatus unknownNCT05639257Not applicable
• Lamotrigine and Bupropion for Meniere's DiseaseStatus unknownNCT05420350Phase 2
• Comparative Bioavailability Study of Lamotrigine ER Tablets USP 50 mgCompletedNCT05145608Phase 1
• MExiletine Versus Lamotrigine in Non-Dystrophic MyotoniasStatus unknownNCT05017155Phase 3
• Bioequivalence of Lamnet (Lamotrigine)100mg Tablet With the Reference Product Lamictal 100mg (Lamotrigine) Tablet Under Fasting ConditionsCompletedNCT04938856Phase 1
• The Effect of a Single Dose of Lamotrigine on Brain Function in Healthy VolunteersCompletedNCT04396938Not applicable
• Ketamine-Induced Brain Changes and Their Modulation by LamotrigineCompletedNCT04156035Not applicable
• A Study to Evaluate the Effect of AG-881 on the Pharmacokinetics of a Single Dose of Lamotrigine in Healthy AdultsCompletedNCT04015687Phase 1
• A Bioequivalence Study of Two Formulations Lamotrigine 100 mg Tablets and Lamictal 100 mg Tablets in Healthy Adult Volunteers Under Fasting ConditionsCompletedNCT03898011Phase 1
• Synaptic Plasticity and Cognitive Function in RASopathiesTerminatedNCT03504501Phase 2
• Protocol Establishment for the Prevention of Lamotrigine-induced Skin Rash in Epilepsy PatientsStatus unknownNCT03220256Phase 2
• Lamotrigine for Ketamine Dependence TrialCompletedNCT02556060Phase 2/3
• Pharmacokinetics, Safety and Tolerability of Repeat Dosing Lamotrigine in Healthy Chinese SubjectsCompletedNCT02513654Phase 1
• A Trial of Generic Substitution of Antiepileptic DrugsStatus unknownNCT02429596Phase 4
• Pharmacovigilance in Gerontopsychiatric PatientsTerminatedNCT02374567Phase 3
• Interaction Between Paracetamol and Lamotrigine: A Clinical Interaction StudyCompletedNCT02303106Phase 4
• Open-label Drug Interaction Study Between Eslicarbazepine Acetate and Lamotrigine.CompletedNCT02283801Phase 1
• Effect of Lamotrigine on Cognition in NF1TerminatedNCT02256124Phase 2/3
• The Bioequivalence Study of Lamotrigine Dispersible/Chewable Tablets 100mg Compared With Compressed Tablet 100 mgCompletedNCT02064465Phase 1
• Lamotrigine as Treatment of MyotoniaCompletedNCT01939561Phase 3
• Lamotrigine Extended-Release Tablets 50 mg Under Fed ConditionCompletedNCT01888757Phase 1
• Bioequivalence Study of Lamotrigine Extended-Release Tablets 50 mg Under Fasting ConditionCompletedNCT01888731Phase 1
• Bioequivalence Study of Lamotrigine Extended-Release Tablets 200mg Under Fed ConditionCompletedNCT01888263Phase 1
• Bioequivalence Study of Lamotrigine Extended-Release Tablets 200mg Under Fasting ConditionCompletedNCT01888250Phase 1
• The Bioequivalence Study of Lamotrigine Dispersible/Chewable Tablets 5mg×5 Compared With Lamotrigine Compressed Tablet 25mg in Chinese Healthy Male SubjectsCompletedNCT01879423Phase 1
• Olanzapine Compared to Lamotrigine in the Prevention of Depressive Episode in the Patients With Bipolar DisorderCompletedNCT01864551Phase 4
• Equivalence Among Antiepileptic Drug Generic and Brand Products in People With Epilepsy: Single-Dose 6-Period Replicate Design (EQUIGEN Single-Dose Study)CompletedNCT01733394Phase 4
• Bioequivalence Study of Lamotrigine Tablets 25 mg (2 x 25 mg Tablets) Under Fed ConditionCompletedNCT01618825Phase 1
• Bioequivalence Study of Lamotrigine Tablets 25 mg (2 x 25 mg Tablets) Under Fasting ConditionCompletedNCT01618799Phase 1
• Bioequivalence Study for Lamotrigine Tablets 200 mg Under Fasting ConditionCompletedNCT01513720Phase 1
• Bioequivalence Study for Lamotrigine Tablets 200 mg Under Fed ConditionCompletedNCT01513681Phase 1
• Lamotrigine Bioequivalence Study to Compare Dispersible Tables With Compressed Tablets in ChinaCompletedNCT01357902Phase 1
• Bioequivalence Study of Lamotrigine 25 mg Chewable Tablets of Dr.Reddy's Under Fed ConditionCompletedNCT01131975Phase 1
• Bioequivalence Study of Lamotrigine 25 mg Chewable Tablets of Dr.Reddy's Under Fasting ConditionCompletedNCT01131949Phase 1
• Study of Lamotrigine 2×25 mg IR Tablets of Torrent Pharmaceuticals Limited, India and Lamictal® (Lamotrigine) 2×25 mg Tablets of GlaxoSmithKline, USA, in Healthy Human Adult Subjects, Under Fasting Conditions.CompletedNCT00939614Phase 1
• Study of Lamotrigine 2 x 25 mg IR Tablets of Torrent Pharmaceuticals Pvt., Ltd., India and Lamictal ® (Lamotrigine) 2 x 25 mg Tablets of Glaxo-SmithKline, USA, in Healthy Human Adult Subjects, Under Fed ConditionsCompletedNCT00939458Phase 1
• The Neuroprotective Effect of Lamotrigine and Interferon Beta 1a in Patients With Relapsing-Remitting Multiple SclerosisStatus unknownNCT00917839Phase 2
• Efficacy and Safety Study of Lamotrigine to Treat Trigeminal NeuralgiaCompletedNCT00913107Phase 2/3
• A Study to Evaluate the Effect of Single Doses of Drug A (Lamotrigine) and Drug B (Vofopitant) Alone and in Combination on Resting Motor Threshold in Healthy SubjectsTerminatedNCT00907985Phase 1
• Lamotrigine Augmentation in Resistant DepressionCompletedNCT00901407Not applicable
• Lamotrigine Cognitive Function Study in Adult Untreated EpilepsiesCompletedNCT00896987Phase 4
• Efficacy and Safety of Antidepressant Augmentation With LamotrigineCompletedNCT00652171Phase 3
• Fasting Study of Lamotrigine Tablets 25 mg to Lamictal® Tablets 25 mgCompletedNCT00650208Phase 1

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