Drug
Esmolol clinical trials
Also written Brevibloc.
- studies test it
- 70
- open now
- 12
- in phase 3
- 9
- first study started
- 2008
Keep track of what changes. Save the esmolol studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Combined with it in one product
Studies by the year they started
70 studies that test it; most in 2010 (6)
| Year | Studies |
|---|---|
| 2008 | 1 |
| 2009 | 4 |
| 2010 | 6 |
| 2011 | 4 |
| 2012 | 2 |
| 2013 | 4 |
| 2014 | 6 |
| 2015 | 5 |
| 2016 | 4 |
| 2017 | 2 |
| 2018 | 3 |
| 2019 | 3 |
| 2020 | 5 |
| 2021 | 3 |
| 2022 | 4 |
| 2023 | 5 |
| 2024 | 4 |
| 2025 | 2 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 6
- Phase 2
- 19
- Phase 3
- 9
- Phase 4
- 25
- No phase
- 18
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 68
Cedars-Sinai Medical Center (3) · Central Hospital, Nancy, France (2) · Hospital de Base (2) · Northwestern University (2) · George Papanicolaou Hospital (2) · Ain Shams University (2) · The Second People's Hospital of Huai'an (1) · David N. Proctor, PhD (1)
Often tested with
Tested in the same studies.
Dexmedetomidine (7) · Lidocaine (4) · Labetalol (2) · Nicardipine (2) · Milrinone (1) · Magnesium Sulfate (1) · Remifentanil (1) · Fentanyl (1)
Studies
Open first, then newest update. How each study uses esmolol is read from its arms, and is right about nine times in ten.
Testing it · 70
- Esmolol Versus Dexmedetomidine for Opioid-sparing in Laparoscopic Gynecological SurgeryRecruitingNot applicableVasiliki SamartziNCT07846722Written as Esmolol hydrochloride
- Effects of Esmolol on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic ShockNot yet recruitingNot applicableFirst Affiliated Hospital of Wannan Medical CollegeNCT07657754Written as Esmolol intravenous infusion
- Esmolol Versus Sufentanil on the Quality of Post-cholecystectomy Recovery Laparoscopic Anaesthesia With Orotracheal Intubation on an Outpatient BasisRecruitingPhase 4University Hospital, LimogesNCT07019818Written as Esmolol Hcl 10Mg/Ml Inj
- POCUS-Guided Esmolol in Septic Shock: A Pilot RCTNot yet recruitingPhase 1/2John BasmajiNCT07313605Written as Esmolol
- Effect of Opioid-free Anaesthesia on Postoperative Delirium in Elderly Patients Undergoing Gastrointestinal SurgeryNot yet recruitingPhase 4Qianfoshan HospitalNCT06958393Written as Esmolol
- Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus SurgeryNot yet recruitingNot applicableAin Shams UniversityNCT06620991Written as Esmolol
- Efficacy of Esmolol in the Identification of Cardiovascular Disorders by Cirrhosis, Diabetes Mellitus and Cardiotoxic TreatmentsRecruitingPhase 3Consorcio Centro de Investigación Biomédica en Red (CIBER)NCT05769868Written as Esmolol Injection [Brevibloc]
- REMAP ECMO - Beta Receptor Modulation TrialRecruitingPhase 2Erasmus Medical CenterNCT06522594Written as Esmolol
- Impact of Administration of Esmolol on Nociception Level-guided Control of Nociception.RecruitingPhase 4Ciusss de L'Est de l'Île de MontréalNCT06291363Written as Esmolol Hydrochloride
- Study of Microvascular Dysfunction, CFR and Cardioprotective Effect of Early Administration of Esmolol in MIRecruitingNot applicableNational Medical Research Center for Cardiology, Ministry of Health of Russian FederationNCT06376630Written as Esmolol Hcl 10Mg/Ml Inj
- Effect of Esmolol on Oxygenation Index in Patients With Acute Respiratory Distress SyndromeRecruitingPhase 3Zhiming JiangNCT06013319Written as Esmolol
- Effects of Low-dose Esmolol on Myocardial Injury After Non-cardiac Surgery in Elderly Frail PatientsRecruitingPhase 4Yongtao SunNCT05635877Written as Esmolol
- Age Comparisons of Exercising Muscle O2 Supply in Healthy Adults: Effects of Esmolol InfusionCompletedEarly Phase 1David N. Proctor, PhDNCT04181606Written as Esmolol infusion
- Concomitant Milrinone and Esmolol Treatment in Patients with Acute Myocardial InfarctionCompletedPhase 2Shantou University Medical CollegeNCT02098629Written as Esmolol
- Lidocaine, Esmolol, or Placebo to Relieve IV Propofol PainTerminatedPhase 2/3Wake Forest University Health SciencesNCT04356352Written as Esmolol
- Esmolol Versus Lidocaine on the Quality of Postoperative Recovery in Patients Undergoing Functional Endoscopic Sinus SurgeryActive, not recruitingPhase 1/2The Second People's Hospital of Huai'anNCT06457100Written as Esmolol Injection
- Esmolol in Sepsis Management:Evaluating Immunomodulatory Effects and Impact on Patient OutcomesCompletedPhase 2Lin ChenNCT06390748Written as esmolol
- Clinical Investigation of Galnobax® for the Treatment of Diabetic Foot UlcersCompletedPhase 1/2Novalead Pharma Private LimitedNCT01113515Written as Esmolol hydrochloride
- Evaluation of Early CRRT InTerventions in Patients With ECMO(ELITE)CompletedPhase 4Beijing Anzhen HospitalNCT03549923Written as Esmolol
- Effect of Dexmedetomidine vs Esmolol or Placebo on Cerebral Hemodynamics in Septic ShockCompletedNot applicableXinchen WangNCT06169475Written as Esmolol Hydrochloride
See all 70 studies that test esmolol →
Given in every arm · 1 — esmolol is usual care beside what is tested
As the comparator · 8 — what is tested is compared with esmolol
- Remifentanil vs Esmolol During Intubation for Cerebral Aneurysm Coil EmbolizationNot yet recruitingNot applicableFatih Sultan Mehmet Training and Research HospitalNCT07660861Written as Esmolol
- Comparison of Effects of Scalp Block and Intravenous Esmolol on Hemodynamic Response Following the Skull Pins Application for Elective Supratentorial CraniotomyCompletedNot applicableKhon Kaen UniversityNCT06268275Written as Esmolol
- Phase 3 Study to Evaluate the Safety and Efficacy of Galnobax® in Treating Diabetic Foot UlcersCompletedPhase 3Novalead Pharma Private LimitedNCT03998436Written as Esmolol Hydrochloride
- Study to Compare Pharmacokinetics & Pharmacodynamics of Warfarin & Esmolol in the Absence & Presence of MEDI0382CompletedPhase 1MedImmune LLCNCT03347968Written as Esmolol
- Long-term PK and Safety/Tolerability Testing LDLL600 Against Esmolol in Healthy VolunteersCompletedPhase 1AOP Orphan Pharmaceuticals AGNCT01741519Written as Brevibloc
- A Comparison of the Perioperative Hemodynamic Effects of Remifentanil and Esmolol in Intracranial SurgeryCompletedPhase 4Diskapi Teaching and Research HospitalNCT01628562Written as Esmolol
- A Pharmacokinetic, Pharmacodynamic, Safety Study With AOP LDLA202, ONO LDL50 and Esmolol in Healthy VolunteersCompletedPhase 1AOP Orphan Pharmaceuticals AGNCT01652898Written as Esmolol hydrochloride
- A Short Term Pharmacokinetic, Pharmacodynamic and Tolerability Study to Compare AOP200704 vs. EsmololCompletedPhase 2AOP Orphan Pharmaceuticals AGNCT01313143Written as Esmolol hydrochloride, infusion
Codes
What other systems call esmolol · ClinicalTrials.gg INT003065
- MeSH (NLM) C036604esmololConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) MDY902UXSRESMOLOLConfirmed FDA, NLM, Wikidata
- RxNorm 49737Confirmed FDA, Wikidata
- Wikidata Q418139esmololConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C72617EsmololOne source FDA
- DrugBank DB00187One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C036604 | esmolol | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | MDY902UXSR | ESMOLOL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 49737 | — | Confirmed FDA, Wikidata |
| Wikidata | Q418139 | esmolol | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C72617 | Esmolol | One source FDA |
| DrugBank | DB00187 | — | One source Wikidata |
Also registered as esmolol hydrochloride (UNII V05260LC8D · RxNorm 203222).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.