Rhinosinusitis clinical trials
The registry lists 330 studies for Rhinosinusitis across more than 10 countries. 55 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Completed
- 169
- Status unknown
- 50
- Recruiting
- 29
- Terminated
- 25
- Not yet recruiting
- 24
- Withdrawn
- 21
Phase
- Phase 3
- 46
- Phase 2
- 46
- Phase 4
- 39
- Phase 1
- 23
- Early Phase 1
- 8
Where
- United States
- 102
- Canada
- 39
- China
- 26
- Germany
- 22
- Egypt
- 19
- France
- 18
Who runs them
Beijing Tongren Hospital (10) · St. Paul's Hospital, Canada (9) · Universitaire Ziekenhuizen KU Leuven (6) · Oregon Health and Science University (6) · Cairo University (6) · Assiut University (6) · University of British Columbia (5) · Keymed Biosciences Co.Ltd (5)
Studies
Recruiting first, then most recently updated. Showing 50 of 330 — search for more.
- Longitudinal Deep Phenotyping of Central Mechanisms in Dysosmia: A Pilot Study Using Electrobulbogram (EBG), Functional MRI (fMRI), and Diffusion-Weighted Imaging (DWI)Enrolling by invitationNCT071494281 country
- Safety and Performance Assessment of the Decongestant Seawater Spray Pocket Valve Enriched With Essential Oils in Patients With Acute Rhinitis Associated With Nasal Obstruction: "DEVALPO"RecruitingNCT05494346Not applicable1 country
- Performance and Safety Assessment of the Mechanical Decongestant Seawater Spray Enriched With Essential Oils From Laboratoires Gilbert in Patient With Acute Rhinitis Associated With Nasal ObstructionRecruitingNCT065802101 country
- Efficacy of Bee Venom Phonophoresis in Treating Chronic Sinusitis:Not yet recruitingNCT07151313Not applicable1 country
- RhinAV_Evaluation of Treatments for Acute Viral Rhinitis, Rhinosinusitis, and RhinopharyngitisRecruitingNCT07383493Not applicable1 country
- Observational Study of RHINOSEDAL in Acute Nasal ObstructionNot yet recruitingNCT076205221 country
- Nasal Potential Difference (NPD) Protocol in Chronic RhinosinusitisRecruitingNCT020381661 country
- The Efficacy and Safety of Raphamin in the Treatment of Acute Rhinosinusitis in Adult PatientsRecruitingNCT06901297Phase 31 country
- Post-market Clinical Follow-up Study of an Isotonic Saline Solution to Manage Nasal Congestion in Case of Flu Symptoms, Colds, Allergic Rhinitis and Rhinosinusitis in Infants and ToddlersNot yet recruitingNCT072572241 country
- The German National CRS Registry (GenreCRS): Clinical Evaluation of the New European Academy for Allergy and Clinical Immunology (EAACI) Criteria for CRSwNP Disease Control, Remission and Cure in a Real-World Evidence Study ApproachNot yet recruitingNCT06815211
- Effect of Photobiostimulation Versus Pulsed Electromagnetic Field on Quality of Life in Adults With Chronic RhinosinusitisRecruitingNCT06986629Not applicable1 country
- Effectiveness of Penthrox vs Placebo in Sinus Procedures, a Clinical TrialRecruitingNCT06750302Phase 1/21 country
- Effect of Dupilumab on Nasal Epithelial Barrier Function in Patients With CRSwNPRecruitingNCT063988731 country
- Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal PolypsRecruitingNCT05009758Not applicable1 country
- Comparative Effects of Therapeutic Ultrasound and Sinus Massage in Chronic Rhinosinusitis: a Randomized Controlled StudyRecruitingNCT06960876Not applicable1 country
- The Effect of Modified Olfactory Training on Postoperative Olfactory Dysfunction in Patients With CRSNot yet recruitingNCT06837051Not applicable1 country
- Impact of Structural and Microenvironmental Abnormalities in Olfactory Cleft on Olfaction in CRSNot yet recruitingNCT068344771 country
- Real-Life Chronic Rhinosinusitis Outcome RegistryRecruitingNCT0467017210 countries
- A Cohort Study on Biomarkers to Predict the Efficacy of Biologics for Chronic Rhinosinusitis with Nasal PolypsNot yet recruitingNCT06801353Phase 41 country
- The Effect of Intra-sinus Application of Betamethasone Dipropionate Nasal Cream on Patients with Chronic Rhinosinusitis Post Functional Endoscopic Sinus Surgery (FESS)RecruitingNCT05882903Phase 21 country
- Real-life Evaluation of the Efficacy of Biologicals in Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)RecruitingNCT066832611 country
- Xiangtong TM Full Degradation Sinus Drug Stent System Prospective, Open, Single-center, Randomized Controlled Clinical TrialNot yet recruitingNCT06669130Not applicable
- Endoscopic Direct "Draf IIa" (Carolyn's Window Approach) Versus Endoscopic Angled "Draf IIa"Approach in Chronic Rhinosinusitis With Frontal Sinus Affection ( A Comparative Study ).Not yet recruitingNCT06668844Not applicable
- Dexamethasone Phonophoresis Versus Laser Acupuncture on Chronic RhinosinusitisEnrolling by invitationNCT06616792Not applicable1 country
- Complicated RhinosinusitisNot yet recruitingNCT066068731 country
- Immunologic Impact of Dupilumab in Patients Suffering From Asthma and Chronic Rhinosinusitis With PolypsNot yet recruitingNCT06556264Phase 4
- Comparative Analysis of Silastic Stenting in Sinus SurgeryNot yet recruitingNCT06502197Not applicable
- Predictive Factors in Chronic Rhinosinusitis With Nasal PolypsNot yet recruitingNCT06459622Not applicable
- Study of CM326 in Participants With Chronic Rhinosinusitis With Nasal PolyposisNot yet recruitingNCT06372678Phase 21 country
- Comparison of Immune Profiles in Chronic Rhinosinusitis Patients After Mepolizumab TreatmentRecruitingNCT05642806Phase 41 country
- th2 Modulation CRSwNPNot yet recruitingNCT06107101Phase 41 country
- Real Life Study of Biologicals in Patients With Severe CRSwNPRecruitingNCT059389721 country
- Basal Instincts: Towards Better Understanding of Basal Cell Function in Chronic Rhinosinusitis With Nasal PolypsRecruitingNCT061295521 country
- Biomarkers of Response to Mepolizumab Treatment in Patients With Nasal Polyps With or Without Bronchial AsthmaRecruitingNCT057083001 country
- Mepolizumab in the Treatment of Patients With Severe Uncontrolled CRSwNP: a Multicentric Real Life Observational StudyNot yet recruitingNCT062587721 country
- Correlation Between the Microbiome and Type 2 Inflammatory Diseases of CRSwNPNot yet recruitingNCT06231004
- Proof of Concept of Remote Management of Chronic Inflammatory Airway Diseases for Patient EmpowermentNot yet recruitingNCT06217419Not applicable
- Steroid-eluting Sinus Stent for Chronic Rhinosinusitis Patients With Uncontrolled Postoperative SymptomsRecruitingNCT06198894Not applicable1 country
- Role of Epithelial Barrier Integrity in Biologic Treatment Response of Severe Asthmatics With/Out Chronic Rhinosinusitis With Nasal Polyps (CRSwNP).RecruitingNCT053658411 country
- The Nasal Microbiome and Its Importance in DiseaseRecruitingNCT050613291 country
- Nasal Microbiota Transfer Therapy in Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)RecruitingNCT05400616Not applicable1 country
- the Prevalence of Chronic Rhinosinusitis Associated With Inflammatory Bowel Disease and Association With Biomarkers of Epithelial Barrier DamageNot yet recruitingNCT06149949
- Prevalence of ENT DiseseasNot yet recruitingNCT06105346
- The Study of Long-term Outcomes of GR1802 in Patients With Chronic Rhinosinusitis With Nasal PolypsNot yet recruitingNCT06015243Phase 2
- A Prospective Single-center Cohort Study of Surgical Treatment of Chronic RhinosinusitisRecruitingNCT060103161 country
- Endoscopic Frontal Sinus Surgery Draf III in Moderate to Severe Eosinophilic Chronic Rhinosinusitis With PolypsRecruitingNCT05979662Not applicable1 country
- Adjunctive Treatment for Chronic Rhinosinusitis With Nasal PolyposisNot yet recruitingNCT03607175Phase 2/31 country
- Mepolizumab and In-office Nasal Polypectomy in Patients With Chronic Rhinosinusitis (CRS). A Three Arm Study.Not yet recruitingNCT05923047Phase 41 country
- Adherence in Global Airways - Steroid Intake and Effects on Chronic RhinosinosinutisRecruitingNCT058430191 country
- Endoscopic Sinus Surgery in Recurrent Acute RhinosinusitisRecruitingNCT04241016Not applicable1 country