Diabetic Foot clinical trials
The registry lists 1,077 studies for Diabetic Foot across more than 10 countries. 222 are recruiting or about to start. 942 of them are mainly about Diabetic Foot (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
ClinicalTrials.gov finds 1,281 studies for Diabetic Foot. How that becomes 1,077 here
This page counts the studies the registry files under Diabetic Foot, and those it files under no condition that list Diabetic Footthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,281Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −30List Diabetic Foot as a condition, but the registry did not file them under itMost often written as “Diabetic Foot Disease” (5), “Foot Ulcers, Diabetic” (4), and “Diabetic Foot Infection” (4). The registry filed them under other conditions only, most often Foot Ulcer (7) and Diabetes Mellitus (6).
- −174Match it another way82 name it in the title, 3 in a keyword, and 89 by a synonym or other text the search reads.
- 1,077The count on this page45 of them list Diabetic Foot in their own words; the registry filed them under no condition.
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Status
Who runs them
University of Texas Southwestern Medical Center (15) · Universidad Complutense de Madrid (14) · Integra LifeSciences Corporation (13) · Centre Hospitalier Universitaire de Nīmes (10) · Anterogen Co., Ltd. (10) · MiMedx Group, Inc. (9) · Smith & Nephew, Inc. (9) · Molnlycke Health Care AB (9)
What is being tested here
Drugs under test in Diabetic Foot studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jun 2027Safety and Efficacy Study of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults With Moderate or Severe Diabetic Foot Infections (DFI) · Phase 3 · MicuRx
- Sep 2027a Prospective, Multicenter, Randomized Controlled Trial, With a Non-randomized Sentinel Cohort, Evaluating the Efficacy of Bioxheal, a Single-layer Placental-derived Biologic in Nonhealing Diabetic Foot Ulcers · Phase 3 · Applied Biologics, LLC
- Sep 2027Phase IIb and III Safety and Efficacy Study Chlorin E6 Gel Photodynamic Therapy for Diabetic Foot Ulcers: · Phase 3 · United Medical and Dental College
- Nov 2026Clinical Utility of an Amniotic Membrane Allograft for Diabetic Foot Ulcer Wound Management · Legacy Medical Consultants
- Nov 2026Modified Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of Hard-to-Heal DFUs · StimLabs
- Nov 2026Intermittent Negative Pressure for Patients With Diabetic Foot Ulcers (INPRESS) Study · Lo Zhiwen Joseph
- Nov 2026Efficacy of Hyaluronic Acid Cream in Preventing Foot Ulceration Risk in Patients With Type 2 Diabetes and Moderate-to-Severe Peripheral Neuropathy: A Randomized Clinical Trial. · University of Malaga
- Nov 2026Rising Tide - Amniotic Tissue(s) Treatments for Chronic Diabetic Foot Ulcers · Tides Medical
- Nov 2026Efficacy and Safety of Cold Atmospheric Plasma Combined With Endovascular Intervention for Diabetic Foot Ulcers With Lower Extremity Arterial Occlusion · Shenyang Medical College
- Nov 2026Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs · C5 Biomedical
Who these studies take
Of the 137 Diabetic Foot studies recruiting now, 96 (70%) set no upper age limit and 12 (9%) stop at 75 or younger. 5 (4%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 10 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (4%) | 5 (4%) |
| 18 | 115 (84%) | 115 (84%) |
| 30 | 133 (97%) | 133 (97%) |
| 40 | 134 (98%) | 134 (98%) |
| 50 | 136 (99%) | 136 (99%) |
| 65 | 136 (99%) | 136 (99%) |
| 75 | 135 (99%) | 135 (99%) |
| 85 | 111 (81%) | 111 (81%) |
Across all 1,077 studies, recruiting or not: 13% stop at 75 or younger and 5% at 65; 4% take children; 0% are for women only and <1% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Diabetic Foot studies take
Of 31 phase 2 interventional studies under Diabetic Foot, half reached primary completion within 33 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 29 mo13–43 · 26 studies | — | — |
| Phase 1/2 | 26 mo18–37 · 18 studies | — | — |
| Phase 2 | 33 mo19–47 · 31 studies | — | — |
| Phase 3 | 42 mo23–64 · 18 studies | — | — |
| Phase 4 | 17 mo11–50 · 21 studies | — | — |
| Interventional, no phase | 22 mo9–39 · 343 studies | 25 mo12–40 · 103 studies | 21 mo7–37 · 240 studies |
| Observational | 28 mo15–59 · 90 studies | — | 29 mo12–94 · 65 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting4
- DiaFootCare to Promote Self-Care of Diabetic Foot Ulcers in OmanNov 2, 2026NCT07815275
- Evaluation of the Safety and Efficacy of Live ASCs in the Treatment of Diabetic Foot Syndrome.Oct 26, 2026NCT06843122
- Efficacy and Safety of a Nitric Oxide Generating Dressing for Diabetic Foot Ulcers (ONWARD)Oct 26, 2026NCT07438951
- Systemic Biochemical Signature and Functional Quality Index of Calcaneal Bone Marrow Aspirate in Adults Undergoing Foot or Ankle SurgeryOct 22, 2026NCT07802106
Newly registered3
- Continuous Monitoring of Plantar Temperature Variations Using Connected Insoles and a Mobile Application for Diabetic Foot.Nov 2, 2026NCT07910721
- Comparison of Negative Pressure Wound Therapy Versus Moist Wound Dressing in Diabetic Foot Ulcer PatientsOct 27, 2026NCT07898202
- Comparative Study of Combination Treatment of Bionerv E+ Versus Vitamin B Complex in Treatment of Diabetic Polyneuropathy in Type 2 Diabetic Patients and Its Effect on Wound HealingOct 16, 2026NCT07877948
Studies
Recruiting first, then most recently updated. Showing 50 of 1,077. Browse all 1,077 → or search them.
- Tibial Nerve Mobilization Versus Multisensory Exercises in Patients With Diabetic Foot UlcerNot yet recruitingNCT07841730Not applicable
- PAW-Hydrogel for Chronic Wound HealingRecruitingNCT07541196Not applicable1 country
- DiaFootCare to Promote Self-Care of Diabetic Foot Ulcers in OmanRecruitingNCT07815275Not applicable1 country
- Continuous Monitoring of Plantar Temperature Variations Using Connected Insoles and a Mobile Application for Diabetic Foot.RecruitingNCT07910721Not applicable1 country
- Comparison of Negative Pressure Wound Therapy Versus Moist Wound Dressing in Diabetic Foot Ulcer PatientsNot yet recruitingNCT07898202Not applicable1 country
- Evaluation of the Safety and Efficacy of Live ASCs in the Treatment of Diabetic Foot Syndrome.RecruitingNCT06843122Phase 21 country
- Efficacy and Safety of a Nitric Oxide Generating Dressing for Diabetic Foot Ulcers (ONWARD)RecruitingNCT074389511 country
- Factors Associated With an Evolution in the Quality of Life of Diabetic Patients With Chronic, Wound-free Charcot FootRecruitingNCT054915771 country
- Placental Cells for Diabetic Foot UlcersNot yet recruitingNCT07686094Phase 11 country
- Subcutaneous Dexpanthenol Administration and Wound EpithelializationNot yet recruitingNCT07395674Not applicable1 country
- Systemic Biochemical Signature and Functional Quality Index of Calcaneal Bone Marrow Aspirate in Adults Undergoing Foot or Ankle SurgeryRecruitingNCT078021061 country
- Comparative Study of Combination Treatment of Bionerv E+ Versus Vitamin B Complex in Treatment of Diabetic Polyneuropathy in Type 2 Diabetic Patients and Its Effect on Wound HealingRecruitingNCT07877948Not applicable1 country
- a Prospective, Multicenter, Randomized Controlled Trial, With a Non-randomized Sentinel Cohort, Evaluating the Efficacy of Bioxheal, a Single-layer Placental-derived Biologic in Nonhealing Diabetic Foot UlcersRecruitingNCT07852338Phase 31 country
- Safety and Efficacy Study of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults With Moderate or Severe Diabetic Foot Infections (DFI)RecruitingNCT05369052Phase 38 countries
- Custom Insole With Transcutaneous Electrical Nerve Stimulation on Clinical Outcomes of Diabetic Foot UlcersRecruitingNCT07109895Not applicable1 country
- On the Move: Center and Home-Based Exercise to Enhance Mobility in Diabetic Foot Ulcer RecoveryNot yet recruitingNCT06894563Not applicable
- BB-101 for the Treatment of Diabetic Lower Leg and Foot UlcersRecruitingNCT06383013Phase 21 country
- Total Contact Soft Cast in Diabetic Foot UlcersRecruitingNCT04210089Not applicable1 country
- Efficacy of Human Placental Membrane Products and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg UlcersRecruitingNCT07364630Not applicable1 country
- Evaluating Autologous Platelet-Rich Fibrin Plasma for Chronic Diabetic Foot UlcersNot yet recruitingNCT07840378Phase 1/2
- Activity Reduction vs Advice for Plantar Hotspots in DiabetesNot yet recruitingNCT07840300Not applicable1 country
- Evaluating Several Cellular, Acellular, and Matrix-like Products (CAMPs) and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot and Venous Leg Ulcers.RecruitingNCT06826339Phase 41 country
- Seltoplasmid Plus Revascularization for Diabetic Infrapopliteal Chronic Limb-Threatening IschemiaNot yet recruitingNCT07827521Phase 41 country
- 18F-FDG PET/CT for Diagnosis of Diabetic Foot OsteomyelitisNot yet recruitingNCT078286912 countries
- Nutritional Status in Adults With Diabetic Foot UlcersNot yet recruitingNCT07621770
- Effect of Stress Ball Applied During Surgical Debridement/Dressing on Pain, Distress, and Physiological Parameters in Patients With Diabetic Foot UlcersRecruitingNCT07119983Not applicable1 country
- Clinical Investigation of Sorbact® DressingsRecruitingNCT05089890Not applicable1 country
- Transverse Tibial Bone Transport (TTT) in the Management of Chronic Diabetic Lower Extremity WoundsRecruitingNCT07444593Not applicable1 country
- Effect of Digital-Supported Foot Care Education in Individuals With Type 2 DiabetesNot yet recruitingNCT07813676Not applicable1 country
- HPTC Versus AFSM in Diabetic Foot UlcersRecruitingNCT07781917Not applicable2 countries
- DFC 004 Biomarkers for Active Diabetic Foot UlcersRecruitingNCT061049691 country
- Clinical Efficacy of Modified Simiao Yongan Decoction and Endovascular Therapy for Diabetic Foot UlcersNot yet recruitingNCT07808502Not applicable1 country
- Diabetic Foot Ulcer Imaging- Study 2RecruitingNCT03942081Not applicable1 country
- A Study Comparing an Investigational Wound Gel With Standard Treatment for Mild to Moderate Diabetic Foot UlcersRecruitingNCT07783087Not applicable1 country
- Phase 1 Study of VELGRAFT, a Living Cellular Construct, in the Management of Chronic Diabetic Foot Ulcers Which Have Attained Granulation TissueRecruitingNCT07498218Phase 11 country
- Phase 2a Dose Finding Study of Nu-3 Gel in Subjects With Mild iDFURecruitingNCT07565506Phase 21 country
- Evaluating the Efficacy of Perinatal Membrane Allografts in Addition to the Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers.RecruitingNCT06437028Not applicable1 country
- CARE-D-FOOT-Nav PilotRecruitingNCT07143175Not applicable1 country
- Development and Pilot Application of a Solution-Focused Intervention for Social Isolation in Elderly Diabetic Foot PatientsNot yet recruitingNCT07787884Not applicable1 country
- Performance and Safety of Mepilex® Up in Leg and Foot Ulcers and Skin TearsNot yet recruitingNCT07782008Not applicable1 country
- Controlled Trial to Evaluate the Safety and Efficacy of CYWC628 (Human Dermal Fibroblast Spheroids) for the Treatment of Refractory Diabetic Foot Ulcers Compared With Standard of CareRecruitingNCT07096934Phase 1/21 country
- The ProActive Study- Integrating a Proactive and Palliative Care Approach to Diabetic Ulcer CareNot yet recruitingNCT07781111
- Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System in the Healing of Diabetic Foot UlcersNot yet recruitingNCT05519501Not applicable
- PREPUP: A Randomized Trial of Bonvadis® Versus Collagenase Ointment in Diabetic Foot UlcersNot yet recruitingNCT07779239Not applicable1 country
- Virtual Reality and Moulage Simulation in Diabetic Foot Wound Care TrainingNot yet recruitingNCT07771062Not applicable
- The Effect of L-Carnitine on Wound Healing in Patients With Diabetic Foot Ulcer.RecruitingNCT07768228Phase 21 country
- Diabetic Foot Ulcers: Shorter Treatment Period Using Custom Felt Relief?RecruitingNCT04058639Not applicable1 country
- Miro3D Wound Matrix for Treatment of Diabetic Foot UlcersRecruitingNCT07632001Not applicable1 country
- Effect of a Coordinated Primary-care-Based MDT-model on the Treatment of Hard-to-heal UlcersRecruitingNCT07747896Not applicable1 country
- INJECTHEAL - Investigation of Chronic Wound Exudate and BiofilmNot yet recruitingNCT077457641 country