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Atezolizumab clinical trials

Also written Tecentriq, MPDL3280A and RO5541267.

Includes 2 studies of Atezolizumab and Recombinant Human Hyaluronidase.

studies test it
430
open now
77
in phase 3
91
first study started
2011
Related medicines add 1 study

Counted the way a researcher would: Atezolizumab with its salts, dosage forms, brands and biosimilars. Looking for a trial to join? Including related medicines shows more you could take part in.

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ClinicalTrials.gov finds 1,009 studies for atezolizumab. How that becomes 430 here

Every study that search finds has been read, apart from the 5 newest, to see whether and how it gives atezolizumab. ClinicalTrials.gov counts as of Nov 14, 2026. How drug pages count

  1. 1,009Found by its intervention search · See all 1,009 hereIt also reads titles, arm labels, keywords and descriptions, and counts the drug’s other names. Of these, 824 name it in an intervention entry. The counts it shows beside each synonym overlap: a study writing two names counts under both.
  2. −71
    Mention it without giving it — earlier treatment, a protocol code, a title naming another drug
  3. −1New since the last reading, not read yet
  4. 937Give atezolizumab to participants
  5. −113Observe patients on it, or give it outside a trial
  6. −8Use it as a tool: an imaging tracer or a test of drug response
  7. −14Compare another treatment with it
  8. −372Give it beside what is tested
  9. 430Test it: the count on this site

Get an email when these change. Save the atezolizumab studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Approvals

The first approval found in each region, with its record

United States
18 May 2016 · TECENTRIQ · BLA 761034 (FDA, Drugs@FDA)
European Union
20 Sept 2017 · Tecentriq · EMEA/H/C/004143 (EMA)

From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out

How studies write it

Studies that test it under each name

Name

Atezolizumab
327
Atezolizumab (MPDL3280A), an engineered anti-PD-L1 antibody
10
Atezolizumab 1200 MG in 20 ML Injection
6
Tecentriq, RO5541267, MPDL3280A
4
Atezolizumab (MPDL3280A), an engineered anti-PDL1 antibody
4

Development codes

MPDL3280A
67
RO5541267
44
RG7446
33
MPDL 328OA
28

Other names

Tecentriq
174

In one entry with another drug

Given together, or one or the other

Atezolizumab & Bevacizumab
3

Studies by the year they started

429 studies that test it; most in 2021 (59); 1 more planned to start later

Studies that test atezolizumab, by start year
YearStudies
20111
20122
20135
20149
201523
201630
201752
201857
201944
202050
202159
202229
202332
202414
202514
20268

By phase

A phase 1/2 study counts in both.

Early Phase 1
7
Phase 1
72
Phase 2
288
Phase 3
91
Phase 4
6
No phase
6

What it is tested for

Each study’s main condition, where its own words name it, so a study counts once.

Carcinoma, Non-Small-Cell Lung
66
Carcinoma, Hepatocellular
33
Breast Neoplasms
23
Triple Negative Breast Neoplasms
22
Urinary Bladder Neoplasms
19
Small Cell Lung Carcinoma
15
Colorectal Neoplasms
14
Neoplasms
13
Melanoma
10
Ovarian Neoplasms
9
Glioblastoma
7
Carcinoma, Renal Cell
7

Who runs them

Industry 116 · Other 314

Hoffmann-La Roche (98) · National Cancer Institute (NCI) (36) · M.D. Anderson Cancer Center (15) · Genentech, Inc. (10) · The Netherlands Cancer Institute (7) · Memorial Sloan Kettering Cancer Center (5) · Gustave Roussy, Cancer Campus, Grand Paris (5) · Centre Leon Berard (4)

Often tested with

Tested in the same studies.

Bevacizumab (75) · Cobimetinib (39) · Carboplatin (19) · Paclitaxel (17) · Alectinib (16) · Vemurafenib (16) · Cabozantinib (15) · Pertuzumab (14)

Related medicines

As reviewed, each with the page that says it.

Coming up

From the study records. Dates are the sponsors’ own estimates and often move.

Tested against it · 8 phase 3 studies under way

Atezolizumab is the comparator. A study of two new drugs counts under both.

New treatments tested with it · 8 most studied

New when their studies opened, with atezolizumab beside them; studies of each.

Reaching primary completion within a year · 65, 9 in phase 3

Studies that test atezolizumab, phase 3 first.

Studies

Open first, then newest update. How each study uses atezolizumab has had a first review, but it may not be perfect: check the study record before relying on it for anything important, and report a problem from its row. Some give it without naming it in an intervention entry: those were found by reading the record.

Testing it · 430

See all 430 studies that test atezolizumab →

Behind its US label · 11 — the studies the FDA label of TECENTRIQ describes

From the Clinical Studies section of TECENTRIQ (2026-05), as openFDA has it. A study the site does not hold is left out.

Tested on its own · 84 — no other medicine in its arm

Showing 20 of 84. See all 84 →

Tested with established drugs · 102 — they are given beside it

Showing 20 of 102. See all 102 →

Tested in a combination · 244 — another drug in the study is under test too

Showing 20 of 244. See all 244 →

Beside an established treatment under test · 66 — an approved drug, surgery or radiation is what the study tests

Tested with atezolizumab: Radiation 28 · Surgery or a procedure 16 · Bevacizumab 13 · Carboplatin 4 · Cisplatin 3 · Pemetrexed 3 · Nivolumab 2 · pembrolizumab 2

Showing 20 of 66. See all 66 →

Beside a new treatment under test · 279 — a new drug, cell therapy or vaccine is what the study tests

New treatments tested with atezolizumab: Tiragolumab 49 · ipatasertib 10 · selicrelumab 5 · inavolisib 4 · zanzalintinib 4 · entinostat 4 · autogene cevumeran 3 · tobemstomig 3

Showing 20 of 279. See all 279 →

Beside supportive care · 18 — a supportive treatment or test is studied
One option of several · 6 — a test or a strategy chooses among drugs
Given beside what is tested · 3 — usual care or a partner of the new treatment
As the comparator · 14 — what is tested is compared with atezolizumab
Observed · 113 — patients on it are followed, or it is given outside a trial

Showing 20 of 113. See all 113 →

As a tool · 8 — an imaging tracer or a test of drug response

Codes

What other systems call atezolizumab · ClinicalTrials.gg INT000150

  • MeSH (NLM) C000594389atezolizumabConfirmed ClinicalTrials.gov, NLM, Wikidata
  • UNII (FDA) 52CMI0WC3YATEZOLIZUMABConfirmed FDA, NLM, Wikidata
  • RxNorm 1792776Confirmed FDA, Wikidata
  • Wikidata Q20707748atezolizumabConfirmed FDA, NLM, Wikidata
  • NCI Thesaurus C106250AtezolizumabOne source FDA
  • DrugBank DB11595One source Wikidata

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.

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