Small Cell Lung Carcinoma clinical trials
The registry lists 1,301 studies for Small Cell Lung Carcinoma across more than 10 countries. 365 are recruiting or about to start. 879 of them are mainly about Small Cell Lung Carcinoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
ClinicalTrials.gov finds 9,770 studies for Small Cell Lung Carcinoma. How that becomes 1,300 here
This page counts the studies the registry files under Small Cell Lung Carcinoma, and those it files under no condition that list Small Cell Lung Carcinomathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 9,770Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −31List Small Cell Lung Carcinoma as a condition, but the registry did not file them under itMost often written as “Small Cell Lung Cancer Extensive Stage” (6), “Extensive Stage Small Cell Lung Carcinoma” (3), and “Extensive Disease Small Cell Lung Cancer” (3). The registry filed 1 of them under no condition at all, and the others under other conditions only, most often Neoplasms (6) and Carcinoma, Non-Small-Cell Lung (6).
- −8,439Match it another way200 name it in the title, 26 in a keyword, and 8,213 by a synonym or other text the search reads.
- 1,300The count on this page94 of them list Small Cell Lung Carcinoma in their own words; the registry filed them under no condition.
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Status
Who runs them
National Cancer Institute (NCI) (65) · AstraZeneca (24) · Amgen (19) · AbbVie (18) · GlaxoSmithKline (15) · Shanghai Pulmonary Hospital, Shanghai, China (15) · Memorial Sloan Kettering Cancer Center (13) · Hoffmann-La Roche (13)
What is being tested here
Drugs under test in Small Cell Lung Carcinoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Adebrelimab | 15 | 2 | 18 |
| Anlotinib | 10 | 3 | 25 |
| Durvalumab | 9 | 4 | 30 |
| AMG 757 | 9 | 6 | 18 |
| Irinotecan | 8 | 7 | 38 |
| Etoposide | 8 | 8 | 37 |
| PM 01183 | 8 | 4 | 15 |
| Alveltamig | 7 | 1 | 7 |
| Carboplatin | 6 | 4 | 33 |
| Tislelizumab | 6 | 1 | 11 |
Drug classes tested here Immune checkpoint inhibitors 72 open · Tyrosine kinase inhibitors (TKIs) 27 open · Antibody-drug conjugates (ADCs) 5 open · Antimitotic agents 4 open · PARP inhibitors 4 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Pharmacogenomics ANDA SNP Clinical Study - Etoposide and Single Nucleotide Polymorphisms · Phase 3 · Han Xu, M.D., Ph.D., FAPCR, Medical Director,, IRB Chair
- Dec 2026A Study Comparing BL-B01D1 With Topotecan in Patients With Recurrent Small Cell Lung Cancer(PANKU-Lung03) · Phase 3 · Sichuan Baili Pharmaceutical Co., Ltd.
- Dec 2026Nano-crystalline Megestrol Acetate Combined With Standard Treatment Versus Standard Treatment for First-line Extensive-stage Small Cell Lung Cancer in the Cachexia Phase · Phase 3 · Changchun GeneScience Pharmaceutical Co., Ltd.
- May 2027A Study of MHB088C Injection Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer · Phase 3 · Qilu Pharmaceutical Co., Ltd.
- Jul 2027A Phase III, Randomized, Double-blind, Multi-center Trial Comparing Efficacy and Safety of Trilaciclib Versus Placebo in Participants With Limited-stage Small Cell Lung Cancer · Phase 3 · Jiangsu Simcere Pharmaceutical Co., Ltd.
- Jul 2027Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC) · Phase 3 · Shanghai Junshi Bioscience Co., Ltd.
- Aug 2027The Efficiency of Surgery and Radiotherapy After SHR-1316 (Adebrelimab) and Platinum-containing Doublet Induction Therapy for Limited-stage Small Cell Lung Cancer · Phase 3 · Shanghai Pulmonary Hospital, Shanghai, China
- Aug 2027A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS). · Phase 3 · Bristol-Myers Squibb
- Aug 2027SRS/SRT/Hypo-RT Versus HA-WBRT for No More Than 10 Brain Metastases in SCLC · Phase 3 · Cancer Institute and Hospital, Chinese Academy of Medical Sciences
- Sep 2027Phase 3 Trial of Tarlatamab (SC vs IV) in Extensive-Stage Small Cell Lung Cancer After Platinum Based First-line Chemotherapy (ES-SCLC) · Phase 3 · Amgen
Who these studies take
Of the 263 Small Cell Lung Carcinoma studies recruiting now, 173 (66%) set no upper age limit and 66 (25%) stop at 75 or younger. 3 (1%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 8 (3%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (<1%) | 1 (<1%) |
| 18 | 256 (97%) | 256 (97%) |
| 30 | 260 (99%) | 260 (99%) |
| 40 | 260 (99%) | 260 (99%) |
| 50 | 262 (100%) | 262 (100%) |
| 65 | 263 (100%) | 263 (100%) |
| 75 | 256 (97%) | 256 (97%) |
| 85 | 188 (71%) | 188 (71%) |
Across all 1,301 studies, recruiting or not: 19% stop at 75 or younger and 1% at 65; 3% take children; <1% are for women only and <1% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Small Cell Lung Carcinoma studies take
Of 204 phase 2 interventional studies under Small Cell Lung Carcinoma, half reached primary completion within 46 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 46 mo29–64 · 143 studies | 44 mo29–63 · 111 studies | — |
| Phase 1/2 | 54 mo44–97 · 98 studies | 54 mo43–74 · 71 studies | — |
| Phase 2 | 46 mo29–84 · 204 studies | 35 mo18–44 · 54 studies | 53 mo36–87 · 150 studies |
| Phase 3 | 41 mo31–48 · 68 studies | 34 mo30–44 · 55 studies | — |
| Interventional, no phase | 52 mo25–73 · 47 studies | — | 52 mo26–73 · 45 studies |
| Observational | 77 mo47–… · 62 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting5
- DAREON®-36: A Study to Test Obrixtamig in Combination With ZL-1310 in People With Advanced Small Cell Lung Cancer or Other Neuroendocrine CancersNov 12, 2026NCT07707895
- A Study Comparing QLC5508 in Combination With QL2107 Versus Tislelizumab Plus Platinum-based Chemotherapy in Participants Wih Treatment-naïve Extensive-Stage Small Cell Lung CancerOct 30, 2026NCT07802821
- SMARCA4/2 Inhibitor for POU2F3-Positive SCLCOct 26, 2026NCT07551635
- A Phase II Clinical Study of SHR-7787 Injection Combined With SHR-1316 Injection in Patients With LS-SCLCOct 19, 2026NCT07798947
- A Study to Test Obrixtamig in Combination With Pumitamig in People With Advanced Small Cell Lung Cancer (Dareon®-Rosetta35)Oct 13, 2026NCT07843940
Results posted2
Stopped3
- Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung CancerTerminatedNov 10, 2026NCT05353439
- Pegzilarginase and Pembrolizumab for Extensive Disease Small Cell Lung CancerTerminatedOct 28, 2026NCT03371979
- Autologous CAR T-Cells Targeting the GD2 Antigen for Lung CancerSuspendedOct 28, 2026NCT05620342
Newly registered14
- Clinical Study on Fuzheng Jiedu Huayu Therapy in Combination With Chemotherapy and Immunotherapy for Improving Survival Rates in Extensive-Stage Small Cell Lung CancerNov 10, 2026NCT07928882
- A Randomized Trial of Standard vs. Hypofractionated Accelerated Radiotherapy for Progression in Limited-Stage Small Cell Lung CancerNov 5, 2026NCT07920549
- 68Ga-labeled Cholecystokinin Receptor (CCK2R) Targeted Molecular Probes in Early Tumor DiagnosisNov 4, 2026NCT07914764
- A Clinical Trial of Gocatamig (MK-6070) With Durvalumab in Participants With Small Cell Lung Cancer (MK-6070-004)Nov 2, 2026NCT07908537
- A Study of TRB191 in Patients With Extensive-stage Small Cell Lung CancerNov 2, 2026NCT07908667
Show 9 moreShow fewer
- Low-Dose Radiotherapy Plus Adebrelimab and Chemotherapy for Extensive-Stage Small Cell Lung CancerNov 2, 2026NCT07909863
- Exploration of Whole-Brain Radiotherapy Combined With PD-1 Inhibitors on Brain InjuryOct 30, 2026NCT07905937
- Implantable Microdevices for in Situ Evaluation of Drug Responses in Lung CancerOct 23, 2026NCT07892300
- A Phase I Study of HS-20093 in Combination With ZG006 With or Without Adebrelimab in Patients With ES-SCLCOct 23, 2026NCT07892625
- A Phase 1 Study of IM-1340 in Participants With Advanced CancerOct 22, 2026NCT07890246
- Real-World Use of Tarlatamab in Chinese Patients With Small-Cell Lung CancerOct 21, 2026NCT07885332
- Propranolol Hydrochloride Combined With Adebrelimab and Platinum-Based Chemotherapy in Small Cell Lung CancerOct 21, 2026NCT07886047
- A Phase III, Randomized, Double-blind, Multi-center Trial Comparing Efficacy and Safety of Trilaciclib Versus Placebo in Participants With Limited-stage Small Cell Lung CancerOct 19, 2026NCT07881705
- Effectiveness and Safety of MRG003 (Becotatug Vedotin) in Relapsed SCLCOct 15, 2026NCT07874581
Studies
Recruiting first, then most recently updated. Showing 50 of 1,301. Browse all 1,301 → or search them.
- BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)RecruitingNCT07625644Phase 316 countries
- Tarlatamab for SCLC Brain MetastasesRecruitingNCT07402343Phase 21 country
- DAREON®-36: A Study to Test Obrixtamig in Combination With ZL-1310 in People With Advanced Small Cell Lung Cancer or Other Neuroendocrine CancersRecruitingNCT07707895Phase 1/211 countries
- A Study of Armored CAR T Cells in People With CancerRecruitingNCT07783477Phase 11 country
- Dual-Target CAR-NK Cells in Relapsed/Refractory Small Cell Lung Cancer (SCLC)RecruitingNCT07480213Phase 1/21 country
- Lurbinectedin With or Without Avelumab in Small Cell Carcinoma of the Bladder (LASER)RecruitingNCT06228066Phase 21 country
- A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).RecruitingNCT06646276Phase 326 countries
- Clinical Study on Fuzheng Jiedu Huayu Therapy in Combination With Chemotherapy and Immunotherapy for Improving Survival Rates in Extensive-Stage Small Cell Lung CancerNot yet recruitingNCT07928882Not applicable1 country
- DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard ChemoimmunotherapyRecruitingNCT07472517Phase 342 countries
- A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [EMBOLD SCLC-301]RecruitingNCT07099898Phase 325 countries
- A Study to Test Obrixtamig in Combination With Pumitamig in People With Advanced Small Cell Lung Cancer (Dareon®-Rosetta35)RecruitingNCT07843940Phase 1/210 countries
- A Study of Therapeutic Drug Monitoring-Based Atezolizumab DosingRecruitingNCT06066138Phase 11 country
- A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)RecruitingNCT07227597Phase 1/213 countries
- A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLCRecruitingNCT07459634Phase 21 country
- A Randomized Trial of Standard vs. Hypofractionated Accelerated Radiotherapy for Progression in Limited-Stage Small Cell Lung CancerNot yet recruitingNCT07920549Phase 2/31 country
- MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung CancerRecruitingNCT05903092Phase 21 country
- A Study With NKT3964 for Adults With Advanced/Metastatic Solid TumorsRecruitingNCT06586957Phase 12 countries
- Low-Dose Radiotherapy Plus Adebrelimab and Chemotherapy for Extensive-Stage Small Cell Lung CancerNot yet recruitingNCT07909863Phase 21 country
- 68Ga-labeled Cholecystokinin Receptor (CCK2R) Targeted Molecular Probes in Early Tumor DiagnosisRecruitingNCT079147641 country
- VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or LymphomaRecruitingNCT03556228Phase 1/22 countries
- Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal VolunteersRecruitingNCT009004191 country
- Dose-escalated Adaptive Radiotherapy of Thoracic Disease for Small Cell Lung CancerRecruitingNCT04952480Phase 21 country
- A Study of TRB191 in Patients With Extensive-stage Small Cell Lung CancerNot yet recruitingNCT07908667Phase 1
- A Clinical Trial of Gocatamig (MK-6070) With Durvalumab in Participants With Small Cell Lung Cancer (MK-6070-004)Not yet recruitingNCT07908537Phase 3
- A Study of Alisertib and Paclitaxel in Patients With Small Cell Lung Cancer (SCLC)RecruitingNCT07465757Phase 23 countries
- A Study of BL-M14D1 in Patients With Locally Advanced or Metastatic Small Cell Lung Cancer, Neuroendocrine Tumors and Other Solid TumorsRecruitingNCT06505824Phase 11 country
- A Study of BL-M14D1 in Combination With Atezolizumab in Patients With Extensive-stage Small Cell Lung CancerRecruitingNCT07654400Phase 21 country
- 177Lu-anti-PD-L1 sdAb in Metastatic Solid TumorsRecruitingNCT06305962Early Phase 11 country
- A Study of Valemetostat in Combination With Atezolizumab in People With Lung CancerRecruitingNCT06807632Phase 11 country
- A Study Comparing QLC5508 in Combination With QL2107 Versus Tislelizumab Plus Platinum-based Chemotherapy in Participants Wih Treatment-naïve Extensive-Stage Small Cell Lung CancerRecruitingNCT07802821Phase 31 country
- Exploration of Whole-Brain Radiotherapy Combined With PD-1 Inhibitors on Brain InjuryRecruitingNCT079059371 country
- 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer DetectionRecruitingNCT06503146Phase 21 country
- Autologous B7-H3 Chimeric Antigen Receptor T Cells in Previously Treated Extensive-Stage Small Cell Lung Cancer With Recurrent or Refractory DiseaseRecruitingNCT07509034Phase 11 country
- A Study of MGC026 in Participants With Advanced Solid TumorsRecruitingNCT06242470Phase 13 countries
- A Study Comparing BL-B01D1 Combined With Tislelizumab Versus Platinum-containing Chemotherapy Combined With Tislelizumab as First-line Treatment in Patients With Extensive-stage Small Cell Lung Cancer(PANKU-Lung07)RecruitingNCT07502300Phase 31 country
- A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung CancerRecruitingNCT07155174Phase 213 countries
- PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56RecruitingNCT04199741Phase 1/21 country
- Study to Confirm Efficacy and Feasibility of Tarlatamab Treatment in Patients With Extensive Stage Small-cell Lung Cancer With Poor Performance StatusRecruitingNCT07803848Phase 21 country
- TC-D101 Cell Therapy for Patients With DLL3-Positive SCLCRecruitingNCT07246304Early Phase 11 country
- SMARCA4/2 Inhibitor for POU2F3-Positive SCLCRecruitingNCT07551635Phase 21 country
- A Study of ASP388B Given by Itself and With Standard Therapies in Participants With Solid TumorsRecruitingNCT07730021Phase 1/22 countries
- A Phase I Study of HS-20093 in Combination With ZG006 With or Without Adebrelimab in Patients With ES-SCLCNot yet recruitingNCT07892625Phase 1
- Implantable Microdevices for in Situ Evaluation of Drug Responses in Lung CancerNot yet recruitingNCT07892300Early Phase 1
- A Phase 1 Study of IM-1340 in Participants With Advanced CancerNot yet recruitingNCT07890246Phase 1
- Study of [212Pb]Pb-DOTAM-MAM279 ([212Pb]Pb-MP0712) in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid TumorsRecruitingNCT07278479Phase 1/21 country
- A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid TumorsRecruitingNCT05914116Phase 1/24 countries
- Propranolol Hydrochloride Combined With Adebrelimab and Platinum-Based Chemotherapy in Small Cell Lung CancerRecruitingNCT07886047Phase 11 country
- Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung CancerRecruitingNCT06801834Phase 323 countries
- A Phase II Clinical Study of SHR-7787 Injection Combined With SHR-1316 Injection in Patients With LS-SCLCRecruitingNCT07798947Phase 21 country
- A Study to Evaluate DJI136, a DLL3-targeted CAR-T TherapyRecruitingNCT07564401Phase 1/24 countries