Atezolizumab: beside a new treatment under test

279 studies: a new drug, cell therapy or vaccine is what the study tests. Page 1 of 3. Open to participants first (64), then studies with results posted, then the rest; newest registration first within each.

A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) ABBV-706 in Combination With Tarlatamab and Atezolizumab in Adult Participants With Extensive Stage-Small Cell Lung CancerNot yet recruitingNCT07895056Phase 2 Report a problem
A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) ABBV-706 in Combination With Alveltamig and Atezolizumab for Adults Participants With Extensive Stage-Small Cell Lung CancerNot yet recruitingNCT07895043Phase 2 Report a problem
A Study of ZL-1310 in Combination With a Checkpoint Inhibitor Versus Standard of Care Platinum Based Chemotherapy With a Checkpoint Inhibitor as First-line Therapy in Participants With Extensive-Stage Small Cell Lung CancerNot yet recruitingNCT07796100Phase 3 Report a problem
NK Cells Plus ICI for SCLC MaintenanceRecruitingNCT07759856Phase 2 Report a problem
DAREON®-36: A Study to Test Obrixtamig in Combination With ZL-1310 in People With Advanced Small Cell Lung Cancer or Other Neuroendocrine CancersRecruitingNCT07707895Phase 1/2 Report a problem
A Study of BL-M14D1 in Combination With Atezolizumab in Patients With Extensive-stage Small Cell Lung CancerRecruitingNCT07654400Phase 2 Report a problem
BL-M14D1 Plus Atezolizumab vs Standard of Care in First-Line Extensive-Stage Small Cell Lung Cancer (BrenDeLL-Lung01)RecruitingNCT07625644Phase 3 Report a problem
Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored StudyEnrolling by invitationNCT07620574Phase 3 Report a problem
DSP-0390 in Combination With Atezolizumab for Small Cell Lung CancerRecruitingNCT07545954Phase 1 Report a problem
Evaluating Safety, Tolerability, and Preliminary Efficacy of YSCH-01 Monotherapy and in Combination With Atezolizumab for Recurrent GlioblastomaRecruitingNCT07538128Early Phase 1 Report a problem
DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard ChemoimmunotherapyRecruitingNCT07472517Phase 3 Report a problem
A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid TumorsRecruitingNCT07407933Phase 1/2 Report a problem
SX-682 and Atezolizumab for the Treatment of Advanced or Metastatic, Recurrent Non-small Cell Lung CancerRecruitingNCT07322341Phase 2 Report a problem
β-alanine in the Treatment of Advanced Hepatocellular CarcinomaRecruitingNCT07317414Phase 2 Report a problem
Fecal Microbiota Transplantation to RESCUE Patients With Unresectable Hcc Progressors to First Line Therapy With AtezolizUmaB and BevacizumabRecruitingNCT07276100Phase 2 Report a problem
A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.RecruitingNCT07235293Phase 2 Report a problem
A Clinical Study of Gocatamig (MK-6070) and Infinatamab Deruxtecan (MK-2400) in People With Small Cell Lung Cancer (MK-6070-003)RecruitingNCT07227597Phase 1/2 Report a problem
A Phase 1 Study of OTS-412 (Recombinant Oncolytic Vaccinia Virus) in Treatment-refractory Solid Tumor PatientsNot yet recruitingNCT07170592Phase 1 Report a problem
A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung CancerRecruitingNCT07155174Phase 2 Report a problem
Iadademstat + SBRT With Atezo in ES-SCLCRecruitingNCT07113691Phase 1 Report a problem
A Study of Natural Killer Cells in Combination With Atezolizumab in People With Acute Myelogenous LeukemiaRecruitingNCT07011004Phase 1 Report a problem
A Prospective Study to Evaluate the Safety and Efficacy of the Combination Therapy of Irpagratinib, Atezolizumab, and Bevacizumab in Patients With Hepatocellular CarcinomaRecruitingNCT07010497Phase 2 Report a problem
A Study of Valemetostat in Combination With Atezolizumab in People With Lung CancerRecruitingNCT06807632Phase 1 Report a problem
A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 in Combination With Valganciclovir (VGCV) and Atezolizumab/Bevacizumab in Subjects With Hepatocellular CarcinomaRecruitingNCT06695026Phase 1/2 Report a problem
A Study of TPST-1120 With Atezolizumab Plus Bevacizumab in Patients With Unresectable or Metastatic HCC Not Previously Treated With Systemic TherapyNot yet recruitingNCT06680258Phase 3 Report a problem
Microbiota Modification for Immuno-oncology in Hepatocellular CarcinomaRecruitingNCT06551272Phase 2 Report a problem
A Study of GSK5764227 in Participants With Advanced Solid Tumors (EMBOLD)RecruitingNCT06551142Phase 1 Report a problem
A Study of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers, Including HCCRecruitingNCT06478693Phase 1 Report a problem
Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL CancerRecruitingNCT06463665Phase 2 Report a problem
A Study of VET3-TGI in Patients With Solid TumorsRecruitingNCT06444815Phase 1 Report a problem
A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)RecruitingNCT06362252Phase 1/2 Report a problem
NOvel Immunotherapy Strategies for Advanced Triple Negative Breast Cancer (TNBC) Patients: TONIC-3 TrialRecruitingNCT06342037Phase 2 Report a problem
Study to Evaluate LB-LR1109, Administered Alone for the Treatment of Solid Tumor and in Combination With Atezolizumab for the Treatment of NSCLCRecruitingNCT06332755Phase 1 Report a problem
A Study of Valemetostat Tosylate (DS-3201b) With Atezolizumab and Bevacizumab in HCCRecruitingNCT06294548Phase 1/2 Report a problem
Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung CancerRecruitingNCT06287775Phase 1/2 Report a problem
ProAgio in Pancreatic Ductal Adenocarcinoma (PDAC)RecruitingNCT06182072Phase 1 Report a problem
A Study of ZL-1310 in Subjects With Small Cell Lung CancerRecruitingNCT06179069Phase 1 Report a problem
Safety and Efficacy of NK510 to Treat Gastric CancerEnrolling by invitationNCT06098898Early Phase 1 Report a problem
Safety and Efficacy of NK510 to Treat NSCLCRecruitingNCT06097962Early Phase 1 Report a problem
LB-100 (PP2A Inhibitor) and Atezolizumab (PD-L1 Inhibitor) in Metastatic Colorectal Cancer PatientsRecruitingNCT06012734Phase 1 Report a problem
HTL0039732 in Participants With Advanced Solid TumoursRecruitingNCT05944237Phase 1/2 Report a problem
FusionVAC22_01: Fusion Transcript-based Peptide Vaccine Combined with Immune Checkpoint InhibitionRecruitingNCT05937295Phase 1 Report a problem
A Phase I Study of ROSE12 Alone and in Combination With Other Anti-tumor Agents in Patients With Solid TumorsRecruitingNCT05907980Phase 1 Report a problem
Clinical Study on the Prevention of Driver Gene Negative Ib-IIIb Lung Cancer Recurrence and Metastasis by Staged Chinese Herbal Medicine Combined With Chemotherapy and Immune Checkpoint InhibitorsRecruitingNCT05834413Not applicable Report a problem
Immunotherapy With CCRT Followed by Surgery for Locally Advanced ESCC PatientsRecruitingNCT05743504Phase 1/2 Report a problem
Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCCRecruitingNCT05733598Phase 2 Report a problem
Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC PatientsRecruitingNCT05703971Phase 1/2 Report a problem
Fecal Microbiota Transfer in Liver Cancer to Overcome Resistance to Atezolizumab/Bevacizumab (FLORA)RecruitingNCT05690048Phase 2 Report a problem
A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study)RecruitingNCT05652686Phase 1/2 Report a problem
ONC201 and Atezolizumab in Obesity-Driven Endometrial CancerRecruitingNCT05542407Phase 1 Report a problem
Evaluation of the Interest to Combine a CD4 Th1-inducer Cancer Vaccine Derived From Telomerase and Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular CarcinomaRecruitingNCT05528952Phase 2 Report a problem
Open Label Phase 2 Basket Trial With Atezolizumab and Tiragolumab in Solid TumorsRecruitingNCT05483400Phase 2 Report a problem
A Phase 2, Open-Label Study of ABSK-011 Combined Atezolizumab or SOC in HCC PatientsEnrolling by invitationNCT05441475Phase 2 Report a problem
A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular CarcinomaRecruitingNCT05440708Phase 1/2 Report a problem
A Study of YL201 in Patients With Advanced Solid TumorsRecruitingNCT05434234Phase 1/2 Report a problem
Efficacy and Safety of Anti-PD-1/PD-L1 Treatment +/- UV1 Vaccination in Patients With Non-small Cell Lung CancerRecruitingNCT05344209Phase 2 Report a problem
Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain MetsRecruitingNCT05317858Phase 3 Report a problem
Study Evaluating the Safety and the Efficacy of Combination of Atezolizumab, Tiragolumab and and Stereotactic Body Radiation Therapy in Patients With Oligometastatic Multiorgan (IMMUNOs-SBRT)RecruitingNCT05259319Phase 1 Report a problem
Phase 1/2 Clinical Trial of CP-506 (HAP) in Monotherapy or With Carboplatin or ICIRecruitingNCT04954599Phase 1/2 Report a problem
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)RecruitingNCT04929223Phase 1 Report a problem
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast CancerRecruitingNCT04802759Phase 1/2 Report a problem
Study to Assess Safety,Tolerability,Efficacy of PM01183 and Atezolizumab in Patients w/ Advanced Small Cell Lung Cancer.RecruitingNCT04253145Phase 1/2 Report a problem
Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver CancerRecruitingNCT03942328Phase 1/2 Report a problem
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast CancerRecruitingNCT03424005Phase 1/2 Report a problem
A Study of Tiragolumab Plus Atezolizumab Compared With Placebo Plus Atezolizumab in Participants With Completely Resected Non-small Cell Lung Cancer Who Have Received Adjuvant Platinum-based ChemotherapyTerminatedNCT06267001Phase 3Results posted Report a problem
A Study Evaluating The Efficacy and Safety of Neoadjuvant Immunotherapy Combinations in Patients With Surgically Resectable Hepatocellular CarcinomaTerminatedNCT05908786Phase 1/2Results posted Report a problem
Tiragolumab and Atezolizumab in Patients With Non-squamous Non-small Cell Lung Cancer (NSCLC) and Untreated Brain MetastasesTerminatedNCT05746481Phase 2Results posted Report a problem
Testing the Combination of Anti-cancer Drugs Atezolizumab and Tiragolumab in People With Advanced Stage Rare Cancers, RARE3 TrialActive, not recruitingNCT05715281Phase 2Results posted Report a problem
A Study to Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid TumorsCompletedNCT05661578Phase 2Results posted Report a problem
A Study Evaluating Efficacy and Safety of Multiple Treatment Combinations in Patients With Locally Advanced Squamous Cell Carcinoma of the Head and Neck (Morpheus-Head and Neck Cancer)CompletedNCT05459129Phase 1/2Results posted Report a problem
Trial of Atezolizumab and Bevacizumab With CHS-388 or Placebo in Patients With Hepatocellular CarcinomaTerminatedNCT05359861Phase 2Results posted Report a problem
An Open-Label, Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab in Combination With Tiragolumab With or Without Atezolizumab in Participants With B-Cell Non-Hodgkin LymphomaTerminatedNCT05315713Phase 1/2Results posted Report a problem
An Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Gastric or Gastroesophageal Junction CarcinomaTerminatedNCT05251948Phase 1/2Results posted Report a problem
Safety and Activity of PolyPEPI1018 Plus Atezolizumab in Colorectal Cancer.CompletedNCT05243862Phase 2Results posted Report a problem
Bomedemstat and Maintenance Immunotherapy for Treatment of Newly Diagnosed Extensive Stage Small Cell Lung CancerTerminatedNCT05191797Phase 1/2Results posted Report a problem
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Melanoma (Morpheus-Melanoma)CompletedNCT05116202Phase 1/2Results posted Report a problem
Study to Assess AFM24 in Combination With Atezolizumab in Selected Advanced/Metastatic EGFR-expressing CancersTerminatedNCT05109442Phase 1/2Results posted Report a problem
Tiragolumab Plus Atezolizumab Versus Atezolizumab in the Treatment of Stage II Melanoma Patients Who Are ctDNA-positive Following ResectionTerminatedNCT05060003Phase 2Results posted Report a problem
A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid TumorsCompletedNCT05001347Phase 2Results posted Report a problem
NT-I7 in Combination With Atezolizumab in Previously Untreated, PD-L1-expressing, Locally Advanced or Metastatic NSCLCTerminatedNCT04984811Phase 2Results posted Report a problem
Testing A New Combination of Anti-cancer Immune Therapies, Atezolizumab and CDX-1127 (Varlilumab) With or Without the Addition of a Third Anti-cancer Drug, Cobimetinib, for Advanced-Stage Biliary Tract CancerActive, not recruitingNCT04941287Phase 2Results posted Report a problem
Plinabulin in Combination With Radiation/Immunotherapy in Patients With Select Advanced Cancers After Progression on PD-1 or PD-L1 Targeted AntibodiesTerminatedNCT04902040Phase 1/2Results posted Report a problem
A Study Evaluating the Safety and Efficacy of Neoadjuvant and Adjuvant Tiragolumab Plus Atezolizumab, With or Without Platinum-Based Chemotherapy, in Participants With Previously Untreated Locally Advanced Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung CancerTerminatedNCT04832854Phase 2Results posted Report a problem
Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Participants With Untreated Extensive-Stage Small Cell Lung CancerCompletedNCT04665856Phase 3Results posted Report a problem
A Study of Atezolizumab Plus Tiragolumab and Atezolizumab Plus Placebo as First-Line Treatment in Participants With Recurrent/Metastatic PD-L1 Positive Squamous Cell Carcinoma of the Head and NeckCompletedNCT04665843Phase 2Results posted Report a problem
A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumors.TerminatedNCT04642365Phase 1Results posted Report a problem
Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of Metastatic Triple Negative Breast Cancer, Urothelial Cancer, or Non-small Cell Lung CancerTerminatedNCT04639245Phase 1/2Results posted Report a problem
Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has SpreadCompletedNCT04631029Phase 1Results posted Report a problem
A Study of Tiragolumab in Combination With Atezolizumab Plus Pemetrexed and Carboplatin/Cisplatin Versus Pembrolizumab Plus Pemetrexed and Carboplatin/Cisplatin in Participants With Previously Untreated Advanced Non-Squamous Non-Small Cell Lung CancerCompletedNCT04619797Phase 2/3Results posted Report a problem
Derazantinib Alone or in Combination With Paclitaxel, Ramucirumab or Atezolizumab in Gastric AdenocarcinomaTerminatedNCT04604132Phase 1/2Results posted Report a problem
A Study of Atezolizumab Plus Tiragolumab in Combination With Paclitaxel and Cisplatin Compared With Paclitaxel and Cisplatin as First-Line Treatment in Participants With Unresectable Locally Advanced, Unresectable Recurrent, or Metastatic Esophageal CarcinomaCompletedNCT04540211Phase 3Results posted Report a problem
A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC)CompletedNCT04513925Phase 3Results posted Report a problem
Vorolanib + Atezolizumab as Maintenance Therapy for Extensive-Stage Small Cell Lung CancerTerminatedNCT04373369Phase 2Results posted Report a problem
A Study of Tiragolumab in Combination With Atezolizumab Compared With Placebo in Combination With Atezolizumab in Patients With Previously Untreated Locally Advanced Unresectable or Metastatic PD-L1-Selected Non-Small Cell Lung CancerCompletedNCT04294810Phase 3Results posted Report a problem
A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung CancerCompletedNCT04256421Phase 3Results posted Report a problem
Safety and Tolerability of SYNB1891 Injection Alone or in Combination With Atezolizumab in Adult ParticipantsTerminatedNCT04167137Phase 1Results posted Report a problem
A Phase I/II Trial Investigating LOAd703 in Combination With Atezolizumab in Malignant MelanomaCompletedNCT04123470Phase 1/2Results posted Report a problem
Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411TerminatedNCT04101357Phase 1/2Results posted Report a problem
Atezolizumab and Varlilumab in Combination With Radiation Therapy for NSCLCTerminatedNCT04081688Phase 1Results posted Report a problem
Derazantinib and Atezolizumab in Patients With Urothelial CancerCompletedNCT04045613Phase 1/2Results posted Report a problem

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