Ovarian Neoplasms clinical trials
The registry lists 3,385 studies for Ovarian Neoplasms across more than 10 countries. 792 are recruiting or about to start. 1,881 of them are mainly about Ovarian Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 5 narrower conditions too, such as Carcinoma, Ovarian Epithelial: 3,844 studies, 867 open.
ClinicalTrials.gov finds 5,341 studies for Ovarian Neoplasms. How that becomes 3,379 here
This page counts the studies the registry files under Ovarian Neoplasms, and those it files under no condition that list Ovarian Neoplasmsthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 5,341Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −443Filed under a narrower condition, counted on its own pageCarcinoma, Ovarian Epithelial 353 · Hereditary Breast and Ovarian Cancer Syndrome 44 · Carcinoma, Endometrioid 18 · Ovarian Germ Cell Cancer 6 · Brenner Tumor 5
- −88List Ovarian Neoplasms as a condition, but the registry did not file them under itMost often written as “Stage III Ovarian Cancer AJCC v6 and v7” (9), “Stage IV Ovarian Cancer AJCC v6 and v7” (9), and “High Grade Serous Ovarian Cancer” (8). The registry filed them under other conditions only, most often Fallopian Tube Neoplasms (28) and Triple Negative Breast Neoplasms (13).
- −1,431Match it another way93 name it in the title, 13 in a keyword, and 1,325 by a synonym or other text the search reads.
- 3,379The count on this page114 of them list Ovarian Neoplasms in their own words; the registry filed them under no condition.
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Status
Who runs them
National Cancer Institute (NCI) (130) · Memorial Sloan Kettering Cancer Center (80) · M.D. Anderson Cancer Center (78) · Gynecologic Oncology Group (75) · AstraZeneca (66) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (40) · Dana-Farber Cancer Institute (36) · Eli Lilly and Company (29)
What is being tested here
Drugs under test in Ovarian Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Bevacizumab | 19 | 19 | 99 |
| Olaparib | 13 | 17 | 63 |
| Paclitaxel | 12 | 28 | 151 |
| Fluzoparib | 12 | 3 | 21 |
| Carboplatin | 11 | 28 | 161 |
| Niraparib | 9 | 6 | 43 |
| Cisplatin | 7 | 9 | 51 |
| Pembrolizumab | 7 | 3 | 35 |
| Cyclophosphamide | 6 | 2 | 35 |
| Apatinib | 6 | 3 | 21 |
Drug classes tested here PARP inhibitors 43 open · Immune checkpoint inhibitors 25 open · Angiogenesis inhibitors 20 open · Tyrosine kinase inhibitors (TKIs) 18 open · Antimitotic agents 17 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Avelumab Program Rollover Study · Phase 3 · EMD Serono Research & Development Institute, Inc.
- Dec 2026Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076) · Phase 3 · Genelux Corporation
- Dec 2026Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery · Phase 3 · CanariaBio Inc.
- Dec 2026JSKN003 in Platinum-Resistant, Relapsed Epithelial Ovarian Cancer · Phase 3 · Jiangsu Alphamab Biopharmaceuticals Co., Ltd
- Dec 2026Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing · Phase 3 · Pfizer
- Feb 2027Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer · Phase 3 · NRG Oncology
- Mar 2027HS-20089 for Injection in Patients With Platinum-Resistant Recurrent Epithelial Ovarian Cancer · Phase 3 · Hansoh BioMedical R&D Company
- Apr 2027Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer · Phase 3 · AbbVie
- Apr 2027Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib · Phase 3 · AstraZeneca
- May 2027A Study of SHR-A1811 in Subjects With Ovarian Cancer · Phase 3 · Jiangsu HengRui Medicine Co., Ltd.
Who these studies take
Of the 604 Ovarian Neoplasms studies recruiting now, 441 (73%) set no upper age limit and 107 (18%) stop at 75 or younger. 39 (6%) take children under 18. 359 (59%) are for women only and 0 (0%) for men only; 45 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 31 (5%) | 14 (2%) |
| 18 | 549 (91%) | 231 (38%) |
| 30 | 585 (97%) | 240 (40%) |
| 40 | 591 (98%) | 241 (40%) |
| 50 | 595 (99%) | 241 (40%) |
| 65 | 591 (98%) | 241 (40%) |
| 75 | 558 (92%) | 231 (38%) |
| 85 | 479 (79%) | 211 (35%) |
Across all 3,385 studies, recruiting or not: 13% stop at 75 or younger and 3% at 65; 8% take children; 66% are for women only and <1% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Ovarian Neoplasms studies take
Of 380 phase 1 interventional studies under Ovarian Neoplasms, half reached primary completion within 50 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 50 mo32–76 · 380 studies | 47 mo29–65 · 210 studies | 54 mo35–82 · 170 studies |
| Phase 1/2 | 65 mo44–88 · 173 studies | 61 mo44–88 · 116 studies | 66 mo45–110 · 57 studies |
| Phase 2 | 47 mo33–72 · 344 studies | 37 mo23–51 · 116 studies | 54 mo40–80 · 228 studies |
| Phase 3 | 59 mo37–89 · 125 studies | 45 mo34–72 · 73 studies | 81 mo48–115 · 52 studies |
| Interventional, no phase | 46 mo23–76 · 293 studies | — | 46 mo23–76 · 282 studies |
| Observational | 61 mo35–185 · 268 studies | 53 mo35–71 · 52 studies | 71 mo35–206 · 216 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting11
- Phase 1 Study of VT-101 in Advanced Ovarian CancerNov 9, 2026NCT07905677
- Clinical Trials Comparing Trastuzumab Plus Bevacizumab With Bevacizumab as First-line Maintenance Therapy for Epithelial Ovarian CancerNov 4, 2026NCT07779538
- Mo-Rez in First- Line (1L) Maintenance Treatment of Non-Homologous Recombination Deficient Ovarian Cancer (Non-HRd OC) [BEHOLD-Ovarian03]Nov 3, 2026NCT07694427
- Polygenic Risk Scores and Multi-cancer Early Detection for Ovarian CancerOct 30, 2026NCT06436248
- A Phase I Study of XS-02 Capsules in Patients With Advanced Solid TumorsOct 26, 2026NCT06531486
Show 6 moreShow fewer
- A Study to Evaluate OPB-201 in Recurrent Endometrial and Platinum-resistant Ovarian Cancer.Oct 26, 2026NCT07664735
- A Phase I/II, First-in-Human Study to Evaluate TJ102 in Participants With Advanced or Metastatic Ovarian Cancer and Other Solid Tumors.Oct 21, 2026NCT07778498
- A Study to Evaluate the Safety,Pharmacokinetics,Pharmacodynamics,and Efficacy of TJ037130 in Adult Participants With Advanced Solid TumorsOct 19, 2026NCT07715747
- A Clinical Trial of Raludotatug Deruxtecan (R-DXd) With or Without Bevacizumab in Participants With Ovarian Cancer Who Have Progressed During Treatment With PARP-inhibitors Treatment on First Line Maintenance (MK-5909-008/ENGOT-ov107/GOG-3142 / REJOICE-Ovarian05)Oct 16, 2026NCT07743164
- A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous ABBV-253 Moves Through the Body in Adult Participants With Advanced Solid TumorsOct 16, 2026NCT07807956
- Torvutatug Samrotecan With or Without Bevacizumab as Maintenance Treatment of Platinum-sensitive Relapsed Epithelial Ovarian CancerOct 16, 2026NCT07816666
Results posted3
- PRO1107 in Patients With Advanced Solid TumorsOct 29, 2026NCT06171789
- Lenvatinib, Pembrolizumab, and Paclitaxel for Treatment of Recurrent Endometrial, Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal CancerOct 21, 2026NCT04781088
- Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal CancerOct 20, 2026NCT03206047
Stopped6
- Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid TumorsTerminatedNov 10, 2026NCT05075993
- AB-1015, an Integrated Circuit T (ICT) Cell Therapy in Patients With Platinum Resistant Epithelial Ovarian CancerTerminatedOct 29, 2026NCT05617755
- A Study of MORAb-202 Versus Investigator's Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube CancerTerminatedOct 28, 2026NCT05613088
- A Study to Evaluate the Safety and Efficacy of OPB-101 in Platinum-resistant Ovarian CancerTerminatedOct 26, 2026NCT07030907
- Atezolizumab, Guadecitabine, and CDX-1401 Vaccine in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal CancerTerminatedOct 20, 2026NCT03206047
Show 1 moreShow fewer
- ADP-A2M4CD8 Monotherapy and in Combination With Nivolumab in HLA-A2+ Subjects With MAGE-A4 Positive Ovarian Cancer (SURPASS-3)TerminatedOct 19, 2026NCT05601752
Newly registered19
- AI-Assisted Remote Monitoring for Patients With or at Risk of Malignant Bowel ObstructionNov 12, 2026NCT07931989
- Identifying Mediators of Exercise-induced Tumor Microenvironment Remodeling to Enhance Primary Chemotherapy Response (IMPROVE-Ovarian)Nov 12, 2026NCT07932106
- Phase Ib/II Clinical Study of QLS5133 Combination Therapy in Advanced Solid TumorsNov 12, 2026NCT07933419
- MIRV in Combination With Suvemcitug for Partially Platinum-Sensitive Ovarian CancerNov 12, 2026NCT07934121
- A Study of LY4336619 in Adult Participants With Advanced Solid TumorsNov 10, 2026NCT07928258
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- A Study of QLS5132 in Platinum-Resistant Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal CancerNov 9, 2026NCT07926048
- A Phase I Study of CG-7321 Monotherapy or Combination Therapy in Advanced Solid TumorsNov 6, 2026NCT07923214
- Peer Ambassador in Gyn Onc TrialsNov 4, 2026NCT07915336
- CR-002 in Adult Participants With Locally Advanced or Metastatic Solid TumorsNov 2, 2026NCT07909031
- Phase 1 Study of VT-101 in Advanced Ovarian CancerOct 29, 2026NCT07905677
- Methylation Profiling in Self-Samples for Identification of (Epi)Genetic Biomarkers for Gynecological CancersOct 28, 2026NCT07902375
- Real-World Study of Mirvetuximab Soravtansine in Adult Participants With Platinum-Resistant FRα-Positive Ovarian, Fallopian Tube, and Peritoneal CancerOct 27, 2026NCT07896421
- A Study to Evaluate YF550 in Participants With Locally Advanced or Metastatic Solid Tumors.Oct 26, 2026NCT07894874
- Feasibility of the "One-Finger Technique" for Identifying the Upper Left Ureter During Para-Aortic LymphadenectomyOct 26, 2026NCT07895212
- Folate Receptor Alpha (FRα) Expression and Heterogeneity in Epithelial Ovarian CancerOct 22, 2026NCT07889843
- Effects of Web-Based Ovarian Cancer Awareness Education on Women's Health Beliefs and Risk-Reducing BehaviorsOct 20, 2026NCT07882485
- AI Analysis of CT Scans to Classify Ovarian Tumours as Benign, Borderline or Malignant Before SurgeryOct 20, 2026NCT07883551
- Radiotherapy for Gynecologic Cancer With Up to 10 Active Metastatic LesionsOct 20, 2026NCT07883798
- EHR Intervention to Increase HBOC Genetic TestingOct 15, 2026NCT07876349
Studies
Recruiting first, then most recently updated. Showing 50 of 3,385. Browse all 3,385 → or search them.
- Tissue Procurement and Natural History Study of Patients With Malignant MesotheliomaRecruitingNCT019505721 country
- Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal CancerRecruitingNCT05739981Phase 1/21 country
- Phase Ib/II Clinical Study of QLS5133 Combination Therapy in Advanced Solid TumorsNot yet recruitingNCT07933419Phase 1/21 country
- Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal CancerRecruitingNCT06915025Phase 31 country
- MIRV in Combination With Suvemcitug for Partially Platinum-Sensitive Ovarian CancerNot yet recruitingNCT07934121Phase 21 country
- Phase II Investigation of Pembrolizumab in Combination With Bevacizumab and Oral Cyclophosphamide in Patients With High Grade Ovarian Cancer and Surgically Documented Minimal Residual Disease After Frontline TherapyRecruitingNCT06083844Phase 21 country
- A Phase I/II, First-in-Human Study to Evaluate TJ102 in Participants With Advanced or Metastatic Ovarian Cancer and Other Solid Tumors.RecruitingNCT07778498Phase 1/22 countries
- Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic CancerRecruitingNCT01174121Phase 21 country
- AI-Assisted Remote Monitoring for Patients With or at Risk of Malignant Bowel ObstructionNot yet recruitingNCT07931989Not applicable1 country
- A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid TumorsRecruitingNCT06270706Phase 12 countries
- Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal HistologiesRecruitingNCT04847063Phase 11 country
- A Study to Evaluate OPB-201 in Recurrent Endometrial and Platinum-resistant Ovarian Cancer.RecruitingNCT07664735Phase 11 country
- Identifying Mediators of Exercise-induced Tumor Microenvironment Remodeling to Enhance Primary Chemotherapy Response (IMPROVE-Ovarian)Not yet recruitingNCT07932106Not applicable1 country
- Identifying Underserved Individuals inTexas With Hereditary Cancer Risk Using Mobile Mammography Units and Telegenetics.RecruitingNCT05649072Not applicable1 country
- Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening TrialRecruitingNCT05564377Phase 22 countries
- Sacituzumab Tirumotecan +/- Pembrolizumab in I/O Exposed Metastatic or Recurrent Ovarian Clear Cell CancerRecruitingNCT07718854Phase 21 country
- A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)RecruitingNCT07318558Phase 330 countries
- A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003).RecruitingNCT06843447Phase 1/29 countries
- Study of CryptiVax-1001 in Maintenance Setting for Advanced Serous Ovarian, Fallopian Tube, or Primary Peritoneal CancerRecruitingNCT07665515Phase 11 country
- A Study of LY4336619 in Adult Participants With Advanced Solid TumorsNot yet recruitingNCT07928258Phase 15 countries
- A Study to Evaluate the Efficacy and Safety of Sacituzumab Tirumotecan (MK-2870) Maintenance Treatment Versus Standard of Care in Participants With Platinum-sensitive Recurrent Ovarian Cancer (MK-2870-022/TroFuse-022/ENGOT-ov84/GOG-3103)RecruitingNCT06824467Phase 329 countries
- A Clinical Trial of Raludotatug Deruxtecan (R-DXd) With or Without Bevacizumab in Participants With Ovarian Cancer Who Have Progressed During Treatment With PARP-inhibitors Treatment on First Line Maintenance (MK-5909-008/ENGOT-ov107/GOG-3142 / REJOICE-Ovarian05)RecruitingNCT07743164Phase 33 countries
- A Study of QLS5132 in Platinum-Resistant Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal CancerNot yet recruitingNCT07926048Phase 3
- Peer Ambassador in Gyn Onc TrialsEnrolling by invitationNCT07915336Not applicable1 country
- CYTALUX Dose Extension StudyNot yet recruitingNCT07469202Phase 4
- Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian CancerRecruitingNCT06580314Phase 33 countries
- Phase 1 Study of VT-101 in Advanced Ovarian CancerRecruitingNCT07905677Phase 11 country
- A Study of Azenosertib (ZN-c3) Versus Investigator's Choice Chemotherapy in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Primary Peritoneal, or Fallopian Tube Cancers Positive for Cyclin E1 Protein ExpressionRecruitingNCT07546500Phase 322 countries
- Clonal Hematopoiesis and Therapy-Emergent Myeloid Neoplasms in Patients With Cancers, CHANCES StudyRecruitingNCT062959651 country
- Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian CancerRecruitingNCT06787612Phase 25 countries
- A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian CancerRecruitingNCT04251052Not applicable3 countries
- Unravelling Tumour Biology In Ovarian Cancer With Precision ImagingRecruitingNCT06084195Not applicable1 country
- The Vanguard Study: Testing a New Way to Screen for CancerRecruitingNCT06995898Not applicable1 country
- A Phase I Study of CG-7321 Monotherapy or Combination Therapy in Advanced Solid TumorsRecruitingNCT07923214Phase 11 country
- Methylation Profiling in Self-Samples for Identification of (Epi)Genetic Biomarkers for Gynecological CancersRecruitingNCT07902375Not applicable1 country
- INtegrating Systematic PatIent-Reported Evaluations in Multi-Disciplinary Tumor Boards: The INSPIRE StudyRecruitingNCT07671937Not applicable1 country
- A Study With NKT3964 for Adults With Advanced/Metastatic Solid TumorsRecruitingNCT06586957Phase 12 countries
- A Study of Raludotatug Deruxtecan With or Without Bevacizumab as First-Line Maintenance Treatment in Non-HRD-Positive Advanced Ovarian Cancer (MK-5909-006, (ENGOT-ov102/GOG-3141/ REJOICE-Ovarian 04)RecruitingNCT07776691Phase 35 countries
- Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including MesotheliomaRecruitingNCT06885697Phase 11 country
- Study of Suvemcitug Plus Chemotherapy in Advanced High-Grade Serous Ovarian CancerNot yet recruitingNCT07920159Phase 2
- Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian CancerRecruitingNCT04918186Phase 22 countries
- Leveraging Methylated DNA Markers (MDMs) in the Detection of Endometrial Cancer, Ovarian Cancer, and Cervical CancerRecruitingNCT050517221 country
- A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid TumorsRecruitingNCT06465069Phase 18 countries
- A Study of Sofe-M in Participants With Selected Advanced Solid TumorsRecruitingNCT06400472Phase 17 countries
- cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual DiseaseRecruitingNCT053668811 country
- A Study of LY4337713 in Participants With FAP-Positive Solid TumorsRecruitingNCT07213791Phase 15 countries
- A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)RecruitingNCT06760819Phase 211 countries
- Polygenic Risk Scores and Multi-cancer Early Detection for Ovarian CancerRecruitingNCT064362481 country
- Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)RecruitingNCT05579366Phase 1/24 countries
- Study to Assess the Efficacy and Safety of Rina-S With or Without Bevacizumab Compared to Investigator's Choice of Platinum-based Chemotherapy With or Without Bevacizumab as Second-line Treatment in Participants With Recurrent Platinum-sensitive Ovarian CancerRecruitingNCT07564141Phase 33 countries