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Glioblastoma clinical trials

The registry lists 2,134 studies for Glioblastoma across more than 10 countries. 466 are recruiting or about to start. 1,605 of them are mainly about Glioblastoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

ClinicalTrials.gov finds 2,281 studies for Glioblastoma. How that becomes 2,128 here

This page counts the studies the registry files under Glioblastoma, and those it files under no condition that list Glioblastomathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 2,281Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −29List Glioblastoma as a condition, but the registry did not file them under itMost often written as “Glioblastoma Multiforme of Brain” (4), “Recurrent Childhood Glioblastoma” (3), and “Adult Brain Glioblastoma” (2). The registry filed them under other conditions only, most often Brain Neoplasms (10) and Glioma (8).
  3. −124Match it another way74 name it in the title, 4 in a keyword, and 46 by a synonym or other text the search reads.
  4. 2,128The count on this page58 of them list Glioblastoma in their own words; the registry filed them under no condition.

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Status

Completed
961
Recruiting
339
Terminated
257
Active, not recruiting
178
Status unknown
155
Not yet recruiting
111

Phase

Phase 2
912
Phase 1
833
Phase 3
114
Early Phase 1
95
Phase 4
8

Where

United States
1,301
France
149
China
142
Germany
132
Canada
118
Spain
94

Who runs them

National Cancer Institute (NCI) (122) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (55) · Duke University (53) · M.D. Anderson Cancer Center (44) · Jonsson Comprehensive Cancer Center (28) · City of Hope Medical Center (23) · Case Comprehensive Cancer Center (22) · Mayo Clinic (22)

What is being tested here

Drugs under test in Glioblastoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Temozolomide2316228
Bevacizumab8495
Cyclophosphamide408
Fludarabine406
Tislelizumab404
Lomustine3521
Pembrolizumab3116
Immunotoxin D2C7-(scdsFv)-PE38KDEL304
Fc-engineered Anti-CD40 Agonist Antibody 2141-V11303
Sintilimab303

Drug classes tested here Alkylating agents 30 open · Immune checkpoint inhibitors 22 open · Tyrosine kinase inhibitors (TKIs) 18 open · Angiogenesis inhibitors 9 open · Antimetabolites 7 open

Coming up

37phase 3 studies under way
189studies finish main data collection within a year6 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 339 Glioblastoma studies recruiting now, 234 (69%) set no upper age limit and 65 (19%) stop at 75 or younger. 27 (8%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 13 (4%) take healthy volunteers.

Recruiting studies that take each age, of 339
AgeWomenMen
1022 (6%)22 (6%)
18326 (96%)326 (96%)
30327 (96%)327 (96%)
40326 (96%)326 (96%)
50326 (96%)326 (96%)
65327 (96%)327 (96%)
75295 (87%)295 (87%)
85259 (76%)259 (76%)

Across all 2,134 studies, recruiting or not: 17% stop at 75 or younger and 6% at 65; 9% take children; 0% are for women only and <1% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Glioblastoma studies take

Of 322 phase 1 interventional studies under Glioblastoma, half reached primary completion within 44 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 144 mo29–73 · 322 studies42 mo27–64 · 82 studies45 mo31–76 · 240 studies
Phase 1/266 mo45–100 · 137 studies55 mo39–75 · 53 studies73 mo50–102 · 84 studies
Phase 256 mo40–87 · 249 studies44 mo35–58 · 51 studies59 mo41–89 · 198 studies
Phase 348 mo44–87 · 43 studies——
Interventional, no phase54 mo36–88 · 149 studies—54 mo37–97 · 131 studies
Observational52 mo33–96 · 99 studies—55 mo33–96 · 84 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 14, 2026.

Started recruiting3

Results posted3

Stopped2

Newly registered9

Show 4 more

Studies

Recruiting first, then most recently updated. Showing 50 of 2,134. Browse all 2,134 → or search them.