ACE inhibitors: all 391 studies that test it

Page 1 of 4. Open to participants first (24), then studies with results posted, then the rest; newest registration first within each.

• Ramipril vs. Amlodipine in Pediatric Hemodialysis PatientsNot yet recruitingNCT07879560Phase 3
• Pharmacologic Therapies to Mitigate Radiation- Associated Heart DiseaseRecruitingNCT07685938Phase 2
• The Effect Of Lisinopril On PolycythemiaRecruitingNCT07594535Phase 4
• Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite AthletesEnrolling by invitationNCT07568574Not applicable
• Rapid and Simultaneous Initiation of Four Guideline-Directed CKD Therapies (RAPID-CKD)Enrolling by invitationNCT07547878Phase 4
• Nifedipine and Enalapril vs Nifedipine and Labetalol for the Treatment of Postpartum Hypertension StudyRecruitingNCT07363343Not applicable
• Single and Twice-daily Dosing of Ramipril on Renal Function in Chronic Kidney Disease Patients With Reduced Ejection Fraction Heart FailureRecruitingNCT07259512Phase 4
• Cardiovascular Protection After Preeclampsia With EnalaprilRecruitingNCT07222852Phase 3
• Short-Term Effects of Antihypertensive Drugs on Postural Balance and Fall RiskRecruitingNCT07099677Not applicable
• Postpartum Evaluation of Nifedipine and Enalapril for HypertensionRecruitingNCT07023003Phase 4
• Cardioprotection on Chemotherapy-Induced CardiotoxicityRecruitingNCT06853951Phase 3
• A Study of Enalapril in Treatment of Venous MalformationsRecruitingNCT06788314Phase 2
• STunning in Acute Myocardial Infarction - BASRecruitingNCT06562582Phase 4
• Effect of Captopril on GLS in Duchenne MyodystrophyRecruitingNCT06485661Early Phase 1
• Timely Recovery After Subclinical Heart FailureRecruitingNCT06341101Phase 4
• Colchicine Versus Beta-blockers, Angiotensin-converting Enzyme Inhibitors, and Statins for Prevention of Chemotherapy-Induced CardiomyopathyNot yet recruitingNCT06304896Phase 1
• Bioequivalence Study of Perindopril Tablets in Healthy Volunteers Under Fasting ConditionsRecruitingNCT06213610Phase 1
• Treatment of Patients With Diabetic Kidney DiseaseNot yet recruitingNCT06187493Not applicable
• A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate CancerRecruitingNCT05530655Early Phase 1
• Safety and Efficacy of ACEI in Alport Syndrome Patients With COL4A3/COL4A4/COL4A5 VariantsNot yet recruitingNCT05133050Not applicable
• Cross-over Study of Coronary Risk Factors With a PolypillRecruitingNCT05030818Phase 4
• Angiotensin Receptor-Neprilysin Inhibition in Chagas Cardiomyopathy With Reduced Ejection Fraction: ANSWER-HF.RecruitingNCT04853758Phase 3
• Effect of Some Drugs on Liver FibrosisRecruitingNCT03770936Phase 3
• Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired PneumoniaRecruitingNCT02735707Phase 3
• Effectiveness and Safety of Combination of Amlodipine and Zofenopril in Hypertensive Patients Versus Each MonotherapyCompletedNCT05279807Phase 4Results posted
• Effectiveness and Safety of Combination of Nebivolol and Zofenopril in Hypertensive patIents Versus Each MonotherapyCompletedNCT05257148Phase 4Results posted
• Oral Combined Hydrochlorothiazide/Lisinopril Versus Oral Nifedipine for Postpartum HypertensionCompletedNCT05049616Phase 4Results posted
• Role of Lisinopril in Preventing the Progression of Non-Alcoholic Fatty Liver Disease, RELIEF-NAFLD StudyActive, not recruitingNCT04550481Phase 2Results posted
• Ramipril for the Treatment of COVID-19CompletedNCT04366050Phase 2Results posted
• Stopping ACE-inhibitors in COVID-19CompletedNCT04353596Phase 4Results posted
• Comparing Nifedipine and Enalapril in Medical Resources Used in the Postpartum PeriodCompletedNCT04236258Phase 4Results posted
• Testing Ramipril to Prevent Memory Loss in People With GlioblastomaCompletedNCT03475186Phase 2Results posted
• N-of-1 Trials In Children With HypertensionCompletedNCT03461003Phase 4Results posted
• ACES - ACE Inhibitors Combined With Exercise for Seniors With HypertensionCompletedNCT03295734Phase 2Results posted
• Optimal Management of HIV Infected Adults at Risk for Kidney Complications in NigeriaTerminatedNCT03201939Phase 2Results posted
• Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of LCZ696 Followed by a 52-week, Double-blind Study of LCZ696 Compared With Enalapril in Pediatric Patients With Heart FailureCompletedNCT02678312Phase 2/3Results posted
• Phase II Study of Perindopril and Regorafenib in mCRCCompletedNCT02651415Phase 2Results posted
• Empagliflozin and ACEi- Effects on Hyperfiltration: BETWEEN StudyCompletedNCT02632747Phase 2Results posted
• Series of N-of-1 Crossover Trials of Antihypertensive Therapy in Adolescents With Essential HypertensionCompletedNCT02412761Not applicableResults posted
• CAndesartan vs LIsinopril Effects on the BRainCompletedNCT01984164Phase 2Results posted
• Cardiomyopathy in DMD: Lisinopril vs. LosartanCompletedNCT01982695Not applicableResults posted
• Lisinopril in Reducing Shortness of Breath Caused by Radiation Therapy in Patients With Lung CancerCompletedNCT01880528Phase 2Results posted
• Ramipril for the Treatment of OligospermiaTerminatedNCT01856361Not applicableResults posted
• Risk Factor Control Before Orthopedic SurgeryTerminatedNCT01837069Phase 4Results posted
• Mitigation of Radiation Pneumonitis and FibrosisCompletedNCT01754909Phase 2Results posted
• The Renin-Angiotensin-Aldosterone System and Parathyroid Hormone Control: The RAAS-PARC StudyCompletedNCT01691781Not applicableResults posted
• Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk SurgeryCompletedNCT01669434Phase 4Results posted
• A Pilot Study of Plasma Renin Activity Guided vs Generic Combination Therapy for HypertensionCompletedNCT01658657Not applicableResults posted
• Comparison Between Losartan and Benazepril in Diabetic Hypertensive Patients Not Controlled by AmlodipineCompletedNCT01603940Phase 4Results posted
• ACE Inhibitors to Decrease Lymphoid Fibrosis in Antiretroviral-Treated, HIV-infected Patients: A Pilot StudyCompletedNCT01535235Phase 4Results posted
• Safety Study of Lisinopril in Children and Adolescents With a Kidney TransplantCompletedNCT01491919Phase 1Results posted
• The Effect and Safety of Lisinopril in Non-hypertensive Men With Infertility From Low Sperm CountCompletedNCT01409837Phase 2Results posted
• A Study of the Effect of LY2189265 on Two Blood Pressure DrugsCompletedNCT01324388Phase 1Results posted
• To Study the Effects of Aliskiren on Albuminuria and Various Biomarkers in Patients With NephropathyTerminatedNCT01302899Phase 2Results posted
• Benazepril Hydrochloride, Lisinopril, Ramipril, or Losartan Potassium in Treating Hypertension in Patients With Solid TumorsTerminatedNCT01234922Phase 2Results posted
• Efficacy and Safety Study to Evaluate Combination Therapy With Nebivolol and Lisinopril vs. Placebo and Monotherapy in Patients With Stage 2 Diastolic HypertensionCompletedNCT01218100Phase 4Results posted
• Angiotensin Converting Enzyme (ACE) Inhibition and Cardiac Allograft VasculopathyCompletedNCT01078363Not applicableResults posted
• Impact of Diabetes on Left Ventricular RemodelingCompletedNCT01052272Phase 2/3Results posted
• Clinical and Cost Effectiveness of ACE Inhibitor, Ramipril, in Intermittent ClaudicantsCompletedNCT01037530Phase 4Results posted
• Lisinopril or Coreg CR® in Reducing Side Effects in Women With Breast Cancer Receiving TrastuzumabCompletedNCT01009918Phase 2Results posted
• Reduction of Night-time Blood Pressure in Pediatric Renal Transplant RecipientsCompletedNCT01007994Phase 2/3Results posted
• A Pharmacodynamic Study to Evaluate the Effect of a Fixed Dose Combination Pill on Blood PressureTerminatedNCT01005290Phase 2Results posted
• Cardiovascular Prevention for Persons With HIVCompletedNCT00982189Not applicableResults posted
• Studying the Effects of Antihypertensives on Individuals at Risk for Alzheimer'sCompletedNCT00980785Phase 4Results posted
• Chronic Subdural Hematoma - Reduction of Recurrence by Treatment With Angiotensin Converting Enzyme InhibitorsTerminatedNCT00915928Not applicableResults posted
• Low Dose Versus Aggressive Inhibition of the Renin-Angiotensin-Aldosterone (RAS) to Treat MicroalbuminuriaCompletedNCT00907374Not applicableResults posted
• Enalapril Maleate and Doxorubicin Hydrochloride in Treating Women With Breast CancerCompletedNCT00895414Not applicableResults posted
• Metabolic Effects of Antihypertensive Drugs on People With Metabolic Syndrome (The MEAD Study)CompletedNCT00887510Phase 4Results posted
• Genes, Fibrinolysis and Endothelial Dysfunction- Dialysis Aim 3TerminatedNCT00878969Phase 3Results posted
• Effect of ACE-inhibitors on Aortic Stiffness in Elderly Patients With Chronic Kidney DiseaseCompletedNCT00874432Phase 2Results posted
• Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on Morbidity-mortality in Patients With Chronic Heart FailureCompletedNCT00853658Phase 3Results posted
• Angiotensin Converting Enzyme Inhibitors During Cardiopulmonary Bypass in Infants and ChildrenCompletedNCT00848250Not applicableResults posted
• Trandolapril 4 mg Tablet Under Fasting ConditionsCompletedNCT00840632Phase 1Results posted
• Trandolapril 4 mg Tablet Under Non-Fasting ConditionsCompletedNCT00840073Phase 1Results posted
• Ramipril 10 mg Capsule in Healthy Subjects Under Fed ConditionsCompletedNCT00829530Phase 1Results posted
• Ramipril 10 mg Capsule in Healthy Subjects Under Fasting ConditionsCompletedNCT00829452Phase 1Results posted
• Ramipril 10 mg Capsule in Healthy Subjects Under Fasting ConditionsCompletedNCT00828321Phase 1Results posted
• Renin Angiotensin Aldosterone System (RAAS) and Fibrinolysis in Humans: ACEi and PE5iCompletedNCT00750308Not applicableResults posted
• Women With Chest Pain and Normal Coronary Arteries StudyTerminatedNCT00743197Not applicableResults posted
• The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow DistributionCompletedNCT00741156Phase 3Results posted
• Study of Inflammation and Oxidative Stress in Persons Undergoing DialysisCompletedNCT00732069Phase 2Results posted
• PREVENTKD (Prevent Risks by Early interVEntion at Nighttime in Type 1 Diabetes for Kidney Disease)TerminatedNCT00729365Phase 3Results posted
• Black Education and Treatment of Hypertension (BEAT HTN)CompletedNCT00661895Phase 4Results posted
• Defining Strategies for Improving Endothelial and Fibrinolytic Dysfunction in ObesityTerminatedNCT00608465Phase 4Results posted
• The RAS, Fibrinolysis and Cardiopulmonary BypassCompletedNCT00607672Phase 4Results posted
• The Antihypertensives and Vascular, Endothelial and Cognitive Function TrialCompletedNCT00605072Phase 2Results posted
• Hypertension in Hemodialysis Patients (Aim 3)TerminatedNCT00582114Phase 3Results posted
• Mechanisms of Ramipril Reduction in the Onset of Type 2 DiabetesTerminatedNCT00574834Early Phase 1Results posted
• VA NEPHRON-D: Diabetes iN Nephropathy StudyTerminatedNCT00555217Phase 3Results posted
• Efficacy of Coreg CR and Lisinopril on Markers for Cardiovascular Functional and Structural DiseaseCompletedNCT00553969Phase 1/2Results posted
• Efficacy and Safety of Aliskiren/Ramipril/Amlodipine Compared With Ramipril/Amlodipine and Aliskiren/Amlodipine in Patients With Metabolic SyndromeTerminatedNCT00542269Phase 4Results posted
• Nephropathy In Type 2 Diabetes and Cardio-renal EventsCompletedNCT00535925Phase 4Results posted
• Study Evaluating The Effect Of Ramipril On Urinary Protein Excretion In Renal Transplant Patients Converted To SirolimusCompletedNCT00502242Phase 4Results posted
• The Vascular Effects of Carvedilol Controlled Release (CR) in Abdominally Obese Hypertensive PatientsCompletedNCT00459056Phase 3Results posted
• Extension Study to Assess Long Term Safety, Tolerability, and Efficacy of Valsartan and Enalapril Combined and Alone in Children With HypertensionCompletedNCT00446511Phase 3Results posted
• Evaluation of Heart Failure Treatment Guided by N-terminal Pro B-type Natriuretic Peptide (NTproBNP) vs Clinical Symptoms and Signs AloneCompletedNCT00391846Phase 4Results posted
• A Study of the Effectiveness and Safety of Ramipril in the Treatment of Hypertension in Children and AdolescentsTerminatedNCT00389519Phase 3Results posted
• The COREG And Lisinopril Combination Therapy In Hypertensive Subjects (COSMOS) TrialCompletedNCT00347360Phase 3Results posted
• A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury.CompletedNCT00248807Not applicableResults posted
• Reducing Total Cardiovascular Risk in an Urban CommunityCompletedNCT00241904Phase 4Results posted

← ACE inhibitors overview