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Irritable Bowel Syndrome clinical trials

The registry lists 1,116 studies for Irritable Bowel Syndrome across more than 10 countries. 208 are recruiting or about to start. 848 of them are mainly about Irritable Bowel Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

ClinicalTrials.gov finds 1,187 studies for Irritable Bowel Syndrome. How that becomes 1,115 here

This page counts the studies the registry files under Irritable Bowel Syndrome, and those it files under no condition that list Irritable Bowel Syndromethemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 1,187Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −23List Irritable Bowel Syndrome as a condition, but the registry did not file them under itMost often written as “Constipation-predominant Irritable Bowel Syndrome” (7), “Irritable Bowel Syndrome With Diarrhea” (4), and “Irritable Bowel Syndrome With Constipation” (4). The registry filed them under other conditions only, most often Constipation (8) and Diarrhea (7).
  3. −49Match it another way44 name it in the title and 5 by a synonym or other text the search reads.
  4. 1,115The count on this page117 of them list Irritable Bowel Syndrome in their own words; the registry filed them under no condition.

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Status

Completed
668
Status unknown
132
Recruiting
126
Not yet recruiting
67
Terminated
60
Withdrawn
22

Phase

Phase 2
168
Phase 3
98
Phase 4
72
Phase 1
39
Early Phase 1
6

Where

United States
344
China
73
Italy
67
United Kingdom
66
Sweden
59
Canada
55

Who runs them

Mayo Clinic (25) · University of Nottingham (17) · Sahlgrenska University Hospital (17) · GlaxoSmithKline (16) · University of California, Los Angeles (15) · Karolinska Institutet (14) · Maastricht University Medical Center (14) · Cairo University (12)

What is being tested here

Drugs under test in Irritable Bowel Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Rifaximin4213
Probiotic2116
Prebiotics204
Inulin204
Brenipatide202
Eluxadoline135
Psyllium105
Saccharomyces cerevisiae115
Methylcellulose104
Escitalopram113

Drug classes tested here Serotonin receptor agonists 1 open · SSRIs 1 open · 5-HT3 antagonists 10 · Antiemetics 6 · SNRIs 4

Coming up

16phase 3 studies under way
62studies finish main data collection within a year2 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 126 Irritable Bowel Syndrome studies recruiting now, 33 (26%) set no upper age limit and 83 (66%) stop at 75 or younger. 18 (14%) take children under 18. 4 (3%) are for women only and 1 (1%) for men only; 28 (22%) take healthy volunteers.

Recruiting studies that take each age, of 126
AgeWomenMen
1012 (10%)12 (10%)
18110 (87%)108 (86%)
30110 (87%)108 (86%)
40111 (88%)108 (86%)
50108 (86%)106 (84%)
6596 (76%)94 (75%)
7557 (45%)57 (45%)
8536 (29%)36 (29%)

Across all 1,116 studies, recruiting or not: 65% stop at 75 or younger and 42% at 65; 12% take children; 7% are for women only and <1% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Irritable Bowel Syndrome studies take

Of 42 phase 2 interventional studies under Irritable Bowel Syndrome, half reached primary completion within 21 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 221 mo14–39 · 42 studies19 mo12–23 · 24 studies—
Phase 330 mo19–55 · 23 studies——
Phase 422 mo17–29 · 24 studies——
Interventional, no phase19 mo9–38 · 357 studies13 mo7–28 · 52 studies21 mo9–40 · 305 studies
Observational40 mo21–109 · 65 studies—53 mo28–193 · 51 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 14, 2026.

Started recruiting2

Results posted1

Stopped1

Newly registered10

Show 5 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,116. Browse all 1,116 → or search them.