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Spasm clinical trials

The registry lists 123 studies for Spasm across more than 10 countries. 7 are recruiting or about to start. 32 of them are mainly about Spasm (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 2 narrower conditions too, such as Trismus: 253 studies, 29 open.

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A study of drug A after surgery for early breast cancer

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Status

Completed
83
Status unknown
20
Terminated
10
Recruiting
3
Not yet recruiting
3
Active, not recruiting
2

Phase

Phase 2
25
Phase 3
21
Phase 4
13
Phase 1
5
Early Phase 1
1

Where

United States
51
France
9
Turkey
9
Canada
7
Israel
5
Spain
4

Who runs them

Shire (4) · Children's Hospital of Philadelphia (3) · National Institute of Neurological Disorders and Stroke (NINDS) (3) · Flex Pharma, Inc. (2) · Hacettepe University (2) · Rhodes Pharmaceuticals, L.P. (2) · Charles University, Czech Republic (2) · Neurana Pharmaceuticals, Inc. (2)

What is being tested here

Drugs under test in Spasm studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Magnesium Sulfate101
Ketamine101
Methylphenidate038
SHP465023
Diazepam002
Tolperisone012
Lisdexamfetamine012
Omega-3 fatty acid002
Nitroglycerin022
Cyclobenzaprine012

Drug classes tested here Stimulants 10

Coming up

0phase 3 studies under way
4studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 4

Who these studies take

Of the 3 Spasm studies recruiting now, 1 (33%) set no upper age limit and 1 (33%) stop at 75 or younger. 1 (33%) take children under 18. 1 (33%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.

Recruiting studies that take each age, of 3
AgeWomenMen
101 (33%)1 (33%)
182 (67%)1 (33%)
302 (67%)1 (33%)
402 (67%)1 (33%)
502 (67%)1 (33%)
652 (67%)1 (33%)
752 (67%)1 (33%)
852 (67%)1 (33%)

Across all 123 studies, recruiting or not: 64% stop at 75 or younger and 59% at 65; 43% take children; 7% are for women only and 4% for men only; 25% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Spasm studies take

Of 11 phase 3 interventional studies under Spasm, half reached primary completion within 11 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 311 mo4–12 · 11 studies——
Interventional, no phase10 mo5–34 · 24 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

Studies

Recruiting first, then most recently updated. Showing 50 of 123. Browse all 123 → or search them.