An observational study in Epilepsy, sponsored by Centre Hospitalier Universitaire, Amiens. Completed at 2 sites in France. Open to participants aged 3 Years to 6 Years. Per ClinicalTrials.gov, last updated 2026-06-12.
Sponsored by Centre Hospitalier Universitaire, Amiens · Observational
This study will included 20 children presenting with epilepsy with spasms. It aims to offer these children, non invasively and without supplementary examinations, a recording of local and cerebral hemodynamic changes concomitant with an electroencephalographic recording during epileptic episodes. This will be carried out by combining optical imaging using near infra-red spectroscopy (NIRS) with electroencephalography (EEG), in a simultaneous high-resolution (HR) recording.
This study is among those based on multimodal analyses of epilepsy, combining methods of analysis of electrical activity (electrical imaging) and hemodynamics (optical imaging).
Surface electroencephalography (EEG) is a precious tool enabling the study of neuronal dysfunction from a functional point view. It is used in the routine follow-up of children with epilepsy. Optical imaging is a promising medical imaging technique. It uses light in the spectral regions of near infra-red as a source of radiation. It is quantitative, rapid, non invasive, and inoffensive which could easily be used at the child's bedside or in a clinical setting and can provide metabolic information about cerebral function.
This study is multidisciplinary, which calls upon the skills of neurophysiologists, biophysicists, and clinicians
1,848 studies on the registry are indexed under Epilepsy; 422 are open to participants now.
This study's enrollment of 14 is below the median of 112 across 540 observational studies indexed under Epilepsy.
Browse Epilepsy studies →Centre Hospitalier Universitaire, Amiens is the lead sponsor of 586 studies on the registry; 185 are open to participants now.
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Children between 3 and 6 years old presenting infantile spasms
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Exclusion Criteria:
Near Infra Red Spectroscopy.
Device: NIRS
Near Infra Red Spectroscopy
changes in HbO
hemodynamic changes in \[HbO\] before spasms, during spasms, and after spasms
Time frame: Day 0
changes in Hbr
hemodynamic changes in \[Hbr\] before spasms, during spasms, and after spasms
Time frame: Day 0
This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier Universitaire, Amiens →