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CompletedNCT07264530Updated Dec 4, 2025

The Relationship of the Joint Blockage and Muscle Spasm

An interventional study of Mobilization technique for sacroiliac joint in NO DECOMPENSATED ILLNESS, Muscle Cramps and Joint Dysfunction, sponsored by Charles University, Czech Republic. Completed at 1 site in Czechia. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-12-04.

Sponsored by Charles University, Czech Republic · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
18 Years to 60 Years
Sex
All
01

Study summary

An interventional study aimed at verifying the effect of sacroiliac joint blockage on changes in piriformis muscle tension. The study was conducted on 40 subjects, both male and female. Physical therapy methods were used to diagnose muscle tension as a diagnostic tool, along with a visual analogue scale. The intervention was performed using manual mobilisation techniques commonly used in clinical practice. The effectiveness was verified using the same physical therapy diagnostic tool as at the beginning. The entire research process is time-consuming, taking up to 1 hour per examinee.

Read the detailed description

Objectives: The main aim of this study is to summarise current knowledge about the relationship between functional joint blockage and chained muscle spasm. To verify the relationship between sacroiliac joint blockage and piriformis muscle using combined therapy as a diagnostic tool, where the main parameter monitored will be the intensity of piriformis muscle irritability before and after sacroiliac joint mobilisation.

Methods: Measurements will be taken on a group of 40 subjects. The research sample consists of people aged 18-60, randomly divided into an experimental and a control group. All subjects underwent an initial palpation examination of the piriformis muscle, during which the level of pain was determined on a numerical pain scale. All subjects then underwent measurement of the piriformis muscle's irritability threshold using the "Beauty-line device 4000 Topline" device. The experimental group then underwent therapeutic intervention in the form of sacroiliac joint mobilisation using the "Cluster of Lasslet" technique. This was followed by 30 minutes of relaxation. The control group received no therapeutic intervention and only 30 minutes of relaxation between the initial and final examinations. Both groups then underwent the same final examination as at the beginning.

The investigators expect a change in piriformis muscle hypertonicity after sacroiliac joint mobilisation, including a reduction in pain in this muscle, at a statistical significance level of 5%.

02

Conditions studied

  • NO DECOMPENSATED ILLNESS
  • Muscle Cramps
  • Joint Dysfunction

Keywords

  • joint blockage
  • muscle spasm
  • muscle irritability
03

In context

Muscle Cramp

65 studies on the registry are indexed under Muscle Cramp; 9 are open to participants now.

This study's enrollment of 40 is below the median of 50 across 59 interventional studies indexed under Muscle Cramp.

Browse Muscle Cramp studies →

Lead sponsor

Charles University, Czech Republic is the lead sponsor of 228 studies on the registry; 76 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • palpation sensitivity of the piriformis muscle in the piriformis line,
  • limited joint play of the sacroiliac joint,
  • pain in the lower back, groin, perineum, buttocks, or hips, tenderness in the sacrum,
  • pain or weakness during resisted abduction at 90° flexion in the hip joint,
  • positive piriformis sign, positive Freiberg's test, positive Trendelenburg's test, or positive Pace's abduction test.
  • At least 50% of the accompanying signs of sacroiliac joint blockage must be present in each subject.

Exclusion criteria

Exclusion Criteria:

  • acute (primarily infectious) diseases,
  • persons in acute condition after an accident,
  • persons recovering from an accident/illness
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
40 participants (actual)

Study arms

  • Experimental
    Experimental investigated group

    Group to which the mobilization technique will be applied to the sacroiliac joint according to "Cluster of Lasslet"

    Procedure: Mobilization technique for sacroiliac joint

  • No intervention
    Control non-investigated group

    A control group that undergoes an initial examination but subsequently receives no therapy. After 30 minutes of quiet rest, it is examined again.

Interventions

  • ProcedureMobilization technique for sacroiliac joint

    The subject lies on their stomach, mobilization maneuvers are performed, a total of 4 maneuvers according to the recommended "Cluster of Lasslet" procedure for the sacroiliac joint.

06

What researchers measure

Primary outcomes

  1. Changing of piriformis muscle irritability

    After removing the sacroiliac joint blockage, the irritability threshold of the piriformis muscle increases and its painfulness decreases. The reduction in pain will be evident based on instrumental measurements using the Beauty-line device and palpation examination.

    Time frame: one hour at all

07

Study locations

1 site
  • Vokovice
    Prague, Czechia
08

References and documents

Individual participant data

Plan to share: No — not enough experience

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 4, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT07264530
Responsible party
Malá Jitka (PhDr. Jitka Malá, Ph.D., Charles University, Czech Republic) — Principal investigator
First posted
Dec 4, 2025
Start date
Nov 10, 2025
Primary completion
Nov 10, 2025
Completion
Nov 10, 2025
Last update
Dec 4, 2025

Study contacts

Miroslav Petr, Doc.
study chair · Charles University, Faculty of physical education and sport

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Dec 2025. You cannot join it, but the record below documents what was studied.

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