A Phase 2 interventional study of Magnesium and Placebo in Bladder Spasms, sponsored by Mayo Clinic. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-13.
Sponsored by Mayo Clinic · Phase 2, Interventional, and Prevention
This research is being done to find out whether intravenous magnesium is effective in the treatment of bladder spasms after urologic surgery.
Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.
Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
- Be undergoing a bladder invasive procedure with or without planned urinary catheter on Mayo Clinic Gonda 7 Outpatient Procedure Center.
Exclusion Criteria:
Subjects having urology surgery per standard of care will receive intravenous magnesium during the surgery.
Drug: Magnesium
Subjects having urology surgery per standard of care will receive intravenous placebo during the surgery.
Drug: Placebo
Intravenous infusion, load 50 mg/Kg with infusion of 15 mg/Kg/hour
Equivalent volume of normal saline
Incidence of bladder spasm
Number of subjects to experience bladder spasms
Time frame: Post-operative, approximately 1 hour
Incidence of bladder spasm above moderate grade
Number of subjects to experience bladder spasms above moderate grade
Time frame: Post-operative, approximately 4 hours
Treatment for bladder spasms
Number of subjects requiring treatment for bladder spasms
Time frame: Post-operative, approximately 4 hours
Patient satisfaction
Assessed using a seven-point Likert scale where 1=strongly dissatisfied, 2=moderately dissatisfied, 3=slightly dissatisfied, 4=neutral, 5=slightly satisfied, 6=moderately satisfied, 7=extremely satisfied
Time frame: Post-operative, approximately 4 hours
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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