Refractive Errors clinical trials
The registry lists 420 studies for Refractive Errors across more than 10 countries. 59 are recruiting or about to start. 226 of them are mainly about Refractive Errors (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 6 narrower conditions too, such as Myopia: 2,017 studies, 330 open.
Get an email when these change. Save the Refractive Errors studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
Alcon Research (96) · Johnson & Johnson Vision Care, Inc. (20) · Essilor International (17) · Zhongshan Ophthalmic Center, Sun Yat-sen University (13) · CooperVision International Limited (CVIL) (12) · Shanghai Eye Disease Prevention and Treatment Center (10) · Democritus University of Thrace (9) · Tianjin Eye Hospital (8)
What is being tested here
Drugs under test in Refractive Errors studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Cyclopentolate | 1 | 0 | 3 |
| Tropicamide | 1 | 0 | 3 |
| Aceclidine | 0 | 3 | 6 |
| Proxymetacaine | 0 | 0 | 2 |
| Brimonidine | 0 | 1 | 1 |
| Tobramycin | 0 | 0 | 1 |
| Dexamethasone | 0 | 0 | 1 |
| Ofloxacin | 0 | 0 | 1 |
| Benoxinate | 0 | 0 | 1 |
| Omega-3 fatty acid | 0 | 0 | 1 |
Drug classes tested here Antimuscarinics 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Clinical Data Collection of Myopic Patients After PTK-PRK With CZM MEL 90 Excimer Laser · London Vision Clinic
- Nov 2026ML Models Predicting Cycloplegic Refractive Error Based on Non-Cycloplegic Parameters in Myopic Adults · Second Affiliated Hospital of Nanchang University
- Dec 2026Cohort Study on Refractive Errors in Preschool Children · Zhongshan Ophthalmic Center, Sun Yat-sen University
- Dec 2026Evaluation of the Agreement Between Automated Program-Operated Phoropter Subjective Refraction and Optometrist-Performed Subjective Refraction · Zhongshan Ophthalmic Center, Sun Yat-sen University
- Dec 2026Consistency of an Automated Subjective Refraction Program Between Personnel With Diverse Professional Backgrounds and Senior Optometrists · Zhongshan Ophthalmic Center, Sun Yat-sen University
- Jan 2027Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN) · National University of Singapore
- Jan 2027Strengthening Community- to- Hospital Eye Care Pathways From Boko Eye Care Center in Rural Assam · Seva Canada Society
- Feb 2027Clinical Validation Study Protocol for SmartEyes Smart Optometry Measurement Device (Medical Device Clinical Validation Study) · The Hong Kong Polytechnic University
- Mar 2027To Study the Effects of Refractive Surgery on OCT Measurements in the Eye · University of Nebraska
- Mar 2027Can Tailored Surgical Incisions Reduce Refractive Error and Dependence on Glasses After Cataract Surgery? · Linkoeping University
Who these studies take
Of the 30 Refractive Errors studies recruiting now, 8 (27%) set no upper age limit and 19 (63%) stop at 75 or younger. 16 (53%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 18 (60%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 14 (47%) | 14 (47%) |
| 18 | 14 (47%) | 14 (47%) |
| 30 | 13 (43%) | 13 (43%) |
| 40 | 16 (53%) | 16 (53%) |
| 50 | 14 (47%) | 14 (47%) |
| 65 | 12 (40%) | 12 (40%) |
| 75 | 11 (37%) | 11 (37%) |
| 85 | 9 (30%) | 9 (30%) |
Across all 420 studies, recruiting or not: 45% stop at 75 or younger and 42% at 65; 31% take children; <1% are for women only and 0% for men only; 43% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Refractive Errors studies take
Of 172 interventional studies with no phase under Refractive Errors, half reached primary completion within 7 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 7 mo2–23 · 172 studies | 4 mo1–10 · 115 studies | 31 mo10–47 · 57 studies |
| Observational | 19 mo8–47 · 42 studies | — | 26 mo8–47 · 35 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Stopped1
- Access to EyeGlasses for School-aged ChildrenTerminatedOct 19, 2026NCT05588362
Newly registered2
- Consistency of an Automated Subjective Refraction Program Between Personnel With Diverse Professional Backgrounds and Senior OptometristsOct 23, 2026NCT07891884
- Evaluation of the Agreement Between Automated Program-Operated Phoropter Subjective Refraction and Optometrist-Performed Subjective RefractionOct 23, 2026NCT07891897
Studies
Recruiting first, then most recently updated. Showing 50 of 420. Browse all 420 → or search them.
- Retinopathy of Prematurity - Visual Function and Retinal StructureNot yet recruitingNCT074277191 country
- Consistency of an Automated Subjective Refraction Program Between Personnel With Diverse Professional Backgrounds and Senior OptometristsNot yet recruitingNCT07891884Not applicable
- Evaluation of the Agreement Between Automated Program-Operated Phoropter Subjective Refraction and Optometrist-Performed Subjective RefractionNot yet recruitingNCT07891897Not applicable
- Dual-Action Lenses for Slowing Myopia in Children and Teens: A Randomized, Double-Blind TrialNot yet recruitingNCT07854457Not applicable1 country
- Comparing Myopia Control Spectacle Lenses and Standard Single Vision Spectacle Lenses in Children With MyopiaNot yet recruitingNCT07839091Not applicable1 country
- ML Models Predicting Cycloplegic Refractive Error Based on Non-Cycloplegic Parameters in Myopic AdultsRecruitingNCT076908131 country
- Clinical Validation Study Protocol for SmartEyes Smart Optometry Measurement Device (Medical Device Clinical Validation Study)Not yet recruitingNCT07803094
- IOL Position and Refractive Change After Nd:YAG Laser Posterior CapsulotomyNot yet recruitingNCT078021451 country
- To Study the Effects of Refractive Surgery on OCT Measurements in the EyeRecruitingNCT058567861 country
- School-based Myopia Prevention Trial for Children With Insufficient Hyperopic ReserveRecruitingNCT07746804Not applicable1 country
- School-based Myopia Control Trial for Children With Premyopia or MyopiaRecruitingNCT07746778Not applicable1 country
- School-based Myopia Prevention Trial for Children With Adequate Hyperopic ReserveRecruitingNCT07746752Not applicable1 country
- IOL Power Formula Prediction Accuracy at the Extremes of Axial Length: A Prospective Outcome Verification StudyNot yet recruitingNCT077247951 country
- Comparison of Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses Versus Non-Medicated Bandage Contact Lenses on Postoperative Pain Control After Photorefractive KeratectomyNot yet recruitingNCT07705763Not applicable1 country
- Cohort Study on Refractive Errors in Preschool ChildrenNot yet recruitingNCT077062181 country
- Survey of Sensory Impairment Indicators Among Adults Aged 65 Years and Older in Xinxing CountyNot yet recruitingNCT076945051 country
- Comparison of PRESBYOND Laser Blended Vision and Conventional Monovision LASIK in Individuals With Presbyopia: A Randomized Clinical StudyRecruitingNCT07512089Not applicable1 country
- Comparing Myopia Control Spectacle Lenses for Visual Comfort, Adaptation, and Satisfaction in Myopic ChildrenNot yet recruitingNCT07683481Not applicable
- Corneal Epithelial Thickness Mapping by Anterior Segment Optical Coherence Tomography in Patients With Refractive ErrorsNot yet recruitingNCT076471461 country
- Community-Based Eye Screening With Structured Referral Tracking for Preventing Avoidable Blindness in Adults in Rawalpindi, PakistanNot yet recruitingNCT07611682Not applicable1 country
- Can Tailored Surgical Incisions Reduce Refractive Error and Dependence on Glasses After Cataract Surgery?Not yet recruitingNCT07623317Not applicable
- Corneal Elastography and Patient Specific ModelingRecruitingNCT030307551 country
- Strengthening Community- to- Hospital Eye Care Pathways From Boko Eye Care Center in Rural AssamNot yet recruitingNCT07333248Not applicable1 country
- Factors Influencing Subjective Visual Quality in Human EyesNot yet recruitingNCT07518316Not applicable
- Morphological Characteristics of the Maxillomandibular Region in a 3D Representation and the Refractive Status of the EyeRecruitingNCT074605571 country
- An Evaluation of Myopia Control Lenses on Wearing Experience in Myopic ChildrenRecruitingNCT07354945Not applicable1 country
- Clinical Data Collection of Myopic Patients After PTK-PRK With CZM MEL 90 Excimer LaserRecruitingNCT069963531 country
- Assessing the Turkish DDIVAT for Visual Acuity MeasurementNot yet recruitingNCT07240480
- Xinxing Eye Cohort StudyNot yet recruitingNCT07257536
- Measurment of Optic Disc Parameters, RNFL Thickness and Ganglion Cell Complex in Myopic, Hypermetropic and Emmetropic Patients Using OCT and Axial Length MeasurmentsNot yet recruitingNCT07241806
- Comparison Of Keratometric Readings Pre and Post Pterygium Excision With Conjunctival Autograft TransplantationEnrolling by invitationNCT07198126Not applicable1 country
- Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN)RecruitingNCT06631339Not applicable1 country
- Measuring Changes In Choroidal Thickness Induced By Prototype Soft Contact Lenses Worn For 1 HourRecruitingNCT07155551Not applicable1 country
- "My Eyes, My Light": Amar Chokh, Amar AloRecruitingNCT071355701 country
- Clinical Investigation of a Novel Spectacle Lens on Slowing Down Juvenile Myopia ProgressionRecruitingNCT06850168Not applicable1 country
- AOSLO-Based Precise Measurement of Retinal Hemodynamics: Development and Application AssessmentNot yet recruitingNCT07051317
- Evaluation of the Effects of Virtual Reality on Preoperative Anxiety in Refractive SurgeryRecruitingNCT07050498Not applicable1 country
- Algorithm-assisted Subjective Refraction Program Dedicated to ChildrenRecruitingNCT07046065Not applicable1 country
- Research on a New Intelligent Mobile Screening and Diagnosis Pattern for Ocular DiseasesNot yet recruitingNCT07003165
- Clinical Study of SMILE 4.0-VISULYZE in Correcting Refractive ErrorsRecruitingNCT06982807Not applicable1 country
- The Objective of This Study is to Evaluate the Perfomance of a Photorefraction Device for Screening Ametropia in Children. Eligible Participants Will Undergo Multiple Refractive Error Measurements, Visual Acuity and Strabismus Assessments During a Single Evaluation Visit.RecruitingNCT06882408Not applicable1 country
- The Beijing Childhood Eye StudyEnrolling by invitationNCT069314441 country
- Correlation Between Preoperative Refraction and Anterior Segment Parameters With ICL VaultEnrolling by invitationNCT05670626Not applicable1 country
- Real-World Study of Myopia Prevention and Control in ChildrenNot yet recruitingNCT068498951 country
- Evaluate the Safety and Effectiveness of the AccuraSee™ IOPCL for Secondary Implantation in the Capsular Bag to Improve Near and/or Intermediate Vision Following Previous Cataract SurgeryRecruitingNCT06625749Not applicable1 country
- Clinical Investigation for a Multifunction Ophthalmic Measurement DeviceRecruitingNCT06565091Not applicable1 country
- Community Intervention and Demonstration Area ConstructionRecruitingNCT05715424Not applicable1 country
- Errors of Refraction Among Primary School ChildrenRecruitingNCT053665431 country
- Identification of Minimum Focal Points in Vision Curve FormationRecruitingNCT062608521 country
- Effect of Colour Temperature of Reading Lamp on Refractive Error DevelopmentRecruitingNCT05733182Not applicable1 country