Myopia clinical trials
The registry lists 1,159 studies for Myopia across more than 10 countries. 225 are recruiting or about to start. 996 of them are mainly about Myopia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Myopia, Degenerative too: 1,204 studies, 237 open.
ClinicalTrials.gov finds 1,401 studies for Myopia. How that becomes 1,158 here
This page counts the studies the registry files under Myopia, and those it files under no condition that list Myopiathemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,401Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −45Filed under a narrower condition, counted on its own pageMyopia, Degenerative 43
- −38List Myopia as a condition, but the registry did not file them under itMost often written as “High Myopia” (24), “Pathologic Myopia” (4), and “Refractive Error - Myopia Axial” (2). The registry filed them under other conditions only, most often Cataract (9) and Refractive Errors (5).
- −160Match it another way57 name it in the title, 13 in a keyword, and 90 by a synonym or other text the search reads.
- 1,158The count on this page68 of them list Myopia in their own words; the registry filed them under no condition.
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Status
Who runs them
CooperVision International Limited (CVIL) (91) · Alcon Research (76) · Johnson & Johnson Vision Care, Inc. (43) · Shanghai Eye Disease Prevention and Treatment Center (41) · CIBA VISION (39) · The Hong Kong Polytechnic University (36) · Bausch & Lomb Incorporated (35) · Essilor International (27)
What is being tested here
Drugs under test in Myopia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Atropine | 15 | 15 | 49 |
| Brimonidine | 1 | 1 | 2 |
| Aceclidine | 0 | 4 | 6 |
| Ophthalmic Solutions | 0 | 1 | 2 |
| Proxymetacaine | 0 | 0 | 2 |
| Mitomycin | 0 | 0 | 2 |
| Pilocarpine | 0 | 0 | 2 |
| Amino Acids, Branched-Chain | 0 | 0 | 1 |
| Cannabinoids | 0 | 0 | 1 |
| Faricimab | 0 | 1 | 1 |
Drug classes tested here Antimuscarinics 15 open · Angiogenesis inhibitors 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Phase III Presbyopia Correction Using the VIS Opti-K™ System · Phase 3 · VIS, Inc.
- Dec 2026The Effectiveness and Safety of Two Low-concentration Atropine Sulfate Eye Drops (0.01%/0.02%) for Delaying the Pediatric Myopia Progression · Phase 3 · Oupushifang Pharmaceutical Technology Co., Ltd.
- Apr 2027Evaluate the Efficacy and Safety of CTO0308 in Pediatric Patients With Myopia · Phase 3 · Taejoon Pharmaceutical Co., Ltd.
- Apr 2027The Effect of Myopia-Control Contact Lenses in New Zealand Chinese Children · Phase 3 · Aston University
- Sep 2027Efficacy of Topical Atropine Eye Drops for Control of Myopia Progression Among Children Attending Mansoura University Ophthalmic Center · Phase 3 · Mansoura University
- Sep 2027Atropine in the Treatment of Myopia Study in Malaysia · Phase 3 · IDB VisionCare SDN BHD
- Oct 2027Study to Evaluate the Efficacy of Alleance® (Atropine Sulfate 0.01%) as a Treatment to Delay Myopia and Axial Ocular Elongation in Children. · Phase 3 · Laboratorios Sophia S.A de C.V.
- Nov 2026Effectiveness and Safety of the TENEO 317 Model 2 Excimer Laser to Treat Myopia With or Without Astigmatism by Transepithelial Photorefractive Keratectomy · Bausch & Lomb Incorporated
- Nov 2026Effect of MyopiaEd Messaging on Improving Eye-use Behavior and Myopia Control Among Primary School Students in China · Zhongshan Ophthalmic Center, Sun Yat-sen University
- Nov 2026Effect of IOP Lowering on Progressive HM · Sun Yat-sen University
Who these studies take
Of the 122 Myopia studies recruiting now, 19 (16%) set no upper age limit and 102 (84%) stop at 75 or younger. 86 (70%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 53 (43%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 73 (60%) | 73 (60%) |
| 18 | 47 (39%) | 47 (39%) |
| 30 | 42 (34%) | 42 (34%) |
| 40 | 42 (34%) | 42 (34%) |
| 50 | 31 (25%) | 31 (25%) |
| 65 | 20 (16%) | 20 (16%) |
| 75 | 20 (16%) | 20 (16%) |
| 85 | 20 (16%) | 20 (16%) |
Across all 1,159 studies, recruiting or not: 65% stop at 75 or younger and 62% at 65; 47% take children; <1% are for women only and 0% for men only; 44% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Myopia studies take
Of 25 phase 3 interventional studies under Myopia, half reached primary completion within 26 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 26 mo11–57 · 25 studies | — | — |
| Phase 4 | 23 mo8–29 · 18 studies | — | — |
| Interventional, no phase | 14 mo3–34 · 434 studies | 6 mo2–24 · 234 studies | 25 mo11–44 · 200 studies |
| Observational | 24 mo10–59 · 96 studies | — | 26 mo11–90 · 87 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting4
- Brimonidine Eye Drops in the Prevention of Myopia ProgressionNov 9, 2026NCT06996236
- Managing Premyopia in Chinese Children Using Artificial Intelligence Assisted Defocus Incorporated Multiple Segments Based Spectacle Lens: a Randomized Controlled Clinical TrialNov 6, 2026NCT07765550
- Evaluation of Two Monthly Silicone Hydrogel Multifocal Toric in Soft Contact Lens WearersNov 4, 2026NCT07829419
- Evaluation of Orthokeratology Lenses With a 5MM Optic Zone DiameterOct 22, 2026NCT07751172
Stopped2
- Efficacy and Safety of Spectacle Lenses With H.A.L.T. MAX Technology on High Myopia Control in Children and AdolescentsWithdrawnNov 2, 2026NCT07120737
- Access to EyeGlasses for School-aged ChildrenTerminatedOct 19, 2026NCT05588362
Newly registered5
- BRIGHT-LIGHT: Studying Red Light Therapy for Severe Short-Sightedness or Short-Sightedness That Worsens Despite Standard TreatmentNov 6, 2026NCT07923019
- The EYERISING StudyNov 2, 2026NCT07909720
- Corneal Biomechanics and Stromal Tissue Characteristics in Patients Undergoing SMILEOct 30, 2026NCT07906327
- Clinical Performance and Outcomes After Toric Lens TransitionOct 27, 2026NCT07898995
- VEP for Assessment SMILE Visual QualityOct 22, 2026NCT07889752
Studies
Recruiting first, then most recently updated. Showing 50 of 1,159. Browse all 1,159 → or search them.
- Brimonidine Eye Drops in the Prevention of Myopia ProgressionRecruitingNCT06996236Phase 21 country
- BRIGHT-LIGHT: Studying Red Light Therapy for Severe Short-Sightedness or Short-Sightedness That Worsens Despite Standard TreatmentNot yet recruitingNCT07923019Not applicable1 country
- Managing Premyopia in Chinese Children Using Artificial Intelligence Assisted Defocus Incorporated Multiple Segments Based Spectacle Lens: a Randomized Controlled Clinical TrialRecruitingNCT07765550Not applicable1 country
- Mobility Performance in Daily Activities Among Children Wearing Spectacle LensesRecruitingNCT07229352Not applicable1 country
- Clinical Performance and Outcomes After Toric Lens TransitionNot yet recruitingNCT07898995Not applicable1 country
- The EYERISING StudyNot yet recruitingNCT07909720Not applicable2 countries
- Evaluation of a New Laser Refractive Vision Correction Using the TENEO™ 317 Model 2RecruitingNCT06997003Not applicable1 country
- Evaluation of Two Monthly Silicone Hydrogel Multifocal Toric in Soft Contact Lens WearersRecruitingNCT07829419Not applicable1 country
- Corneal Biomechanics and Stromal Tissue Characteristics in Patients Undergoing SMILENot yet recruitingNCT079063271 country
- The Efficacy of a Polarized Folded Optical Path-based Reading-writing Desk for Myopia Prevention and Control in Pre-myopic ChildrenNot yet recruitingNCT07914114Not applicable1 country
- Children's Viewing BehaviorRecruitingNCT07229365Not applicable1 country
- Using Contact Lenses and Spectacle Lenses as Myopia Interventions.Not yet recruitingNCT07845721Not applicable2 countries
- A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia ControlRecruitingNCT07095894Phase 31 country
- Therapeutic Efficacy of Different Repeated Low-Intensity Red Light Devices and Different Usage FrequenciesEnrolling by invitationNCT07186088Not applicable1 country
- Evaluation of Orthokeratology Lenses With a 5MM Optic Zone DiameterRecruitingNCT07751172Not applicable2 countries
- SmoothCore Orthokeratology Plus M.O.V.E. Lenses vs. M.O.V.E. Lenses Alone for Myopia Control in Children With High MyopiaNot yet recruitingNCT07854366Not applicable
- Wavelength Intervention for Nearsighted KidsRecruitingNCT06598423Not applicable1 country
- Clinical Efficacy and Mechanism Exploration of MR-61 in Delaying the Progression of MyopiaRecruitingNCT07298824Phase 21 country
- Early Intervention for High Risk Premyopic ChildrenNot yet recruitingNCT07863713Phase 2
- Dual-Action Lenses for Slowing Myopia in Children and Teens: A Randomized, Double-Blind TrialNot yet recruitingNCT07854457Not applicable1 country
- Screening for Hyperopic Reserve in KindergartenRecruitingNCT078515321 country
- Control of Myopia in Young Children Using H.O.P.E. Lenses Combined With 0.02% Atropine Eye DropsNot yet recruitingNCT07846787Not applicable1 country
- Study of Eye Fatigue From Digital Screens and Its Impact on Visual Performance in People With Normal Vision and Myopia, With and Without Dry Eye Symptoms and SignsNot yet recruitingNCT07844408Not applicable1 country
- Comparing Myopia Control Spectacle Lenses and Standard Single Vision Spectacle Lenses in Children With MyopiaNot yet recruitingNCT07839091Not applicable1 country
- Comparison of Hand Eye Coordination and Sports Vision Performance in Dual-Focus Multifocal Contact Lenses and Habitual Contact LensesRecruitingNCT07840209Not applicable1 country
- Delaying the Onset of Nearsightedness Until Treatment (DONUT) Clinical TrialRecruitingNCT07567040Phase 31 country
- AI-Stratified Myopia Control for Children in Remote AreasNot yet recruitingNCT07825428Not applicable1 country
- Myopia Control Using Novel Soft Contact LensesRecruitingNCT07547085Not applicable1 country
- Choroidal Response to the Modified Defocus Incorporated Multiple Segments Spectacle LensesRecruitingNCT07547072Not applicable1 country
- Visual and Postural Behavior in Myopic and Non-Myopic TeenagersRecruitingNCT07440134Not applicable1 country
- Clinical Applications of Advanced Ophthalmic ImagingRecruitingNCT03135327Not applicable1 country
- Eye Imaging for the Study of Childhood MyopiaRecruitingNCT07335146Not applicable1 country
- Targeted Lens Intervention for Myopic Anisometropia in ChildrenRecruitingNCT07533149Not applicable1 country
- Effect of a Myopia Control Lens on the Astigmatism in ChildrenNot yet recruitingNCT07810725Not applicable
- Efficacy of Myopia-control Lenses in a Population of Young Adults : the OPTIMA StudyNot yet recruitingNCT07804043Not applicable1 country
- Functional Vision and Quality of Life in a Modern Society - With Emphasis on Myopia and Cerebral Visual Impairment Among YouthRecruitingNCT076530741 country
- Study of an Implantable Collamer Lens (ICL)Not yet recruitingNCT07791381Not applicable
- Evaluation of Mesopic Visual Acuity and Patient Satisfaction Following Ray-Tracing-Guided LASIKRecruitingNCT07790185Phase 41 country
- Study of a Phakic Implantable Collamer Lens (ICL)Not yet recruitingNCT07790965Not applicable
- To Study the Effects of Refractive Surgery on OCT Measurements in the EyeRecruitingNCT058567861 country
- SMILE Surgery in One Eye Compared to Ray Tracing-guided LASIK Surgery in the Fellow EyeRecruitingNCT07721714Phase 41 country
- Children Receiving Monocular MiSight® 1 Day Treatment for Unilateral MyopiaNot yet recruitingNCT07778264
- A Pilot Evaluation of Refractive Error Progression in Pre-Myopic Children in Singapore With and Without Myopia Control SpectaclesNot yet recruitingNCT07779941Not applicable1 country
- Safety and Efficacy Study of A Viscoelastic-free Method for Implantable Collamer Lens (ICL) ImplantationRecruitingNCT03059043Not applicable1 country
- Exploring Perceptual Learning in Blurred Gabor Discrimination for Low-Myopic ChildrenNot yet recruitingNCT07107646Not applicable1 country
- Assessing the Impact of Streetscape Exposure on Children's PerceptionRecruitingNCT077619491 country
- Risk of Posterior Staphyloma in Highly Myopic Europeans : From Epidemiology to Anatomy.RecruitingNCT06949579Not applicable1 country
- China Children Eye StudyRecruitingNCT057706611 country
- School-based Myopia Control Trial for Children With Premyopia or MyopiaRecruitingNCT07746778Not applicable1 country
- School-based Myopia Prevention Trial for Children With Adequate Hyperopic ReserveRecruitingNCT07746752Not applicable1 country