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Presbyopia clinical trials

The registry lists 336 studies for Presbyopia across more than 10 countries. 35 are recruiting or about to start. 233 of them are mainly about Presbyopia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.

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Status

Completed
233
Status unknown
34
Recruiting
18
Terminated
16
Not yet recruiting
15
Active, not recruiting
10

Phase

Phase 3
30
Phase 2
20
Phase 4
14
Phase 1
7
Early Phase 1
1

Where

United States
131
Greece
20
United Kingdom
17
Spain
15
China
13
Canada
12

Who runs them

Alcon Research (36) · Democritus University of Thrace (20) · CooperVision International Limited (CVIL) (15) · AcuFocus, Inc. (11) · Beaver-Visitec International, Inc. (10) · Johnson & Johnson Vision Care, Inc. (10) · Technolas Perfect Vision GmbH (9) · CIBA VISION (9)

What is being tested here

Drugs under test in Presbyopia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Pilocarpine2510
Aceclidine049
Brimonidine036
Macrophage Colony-Stimulating Factor036
AGN-190584016
Phentolamine023
Carbachol023
Mitomycin003
Oxymetazoline001

Coming up

2phase 3 studies under way
8studies finish main data collection within a year1 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 8, phase 3 first

Who these studies take

Of the 18 Presbyopia studies recruiting now, 7 (39%) set no upper age limit and 9 (50%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 7 (39%) take healthy volunteers.

Recruiting studies that take each age, of 18
AgeWomenMen
100 (0%)0 (0%)
184 (22%)4 (22%)
305 (28%)5 (28%)
4011 (61%)11 (61%)
5015 (83%)15 (83%)
6514 (78%)14 (78%)
7512 (67%)12 (67%)
858 (44%)8 (44%)

Across all 336 studies, recruiting or not: 41% stop at 75 or younger and 28% at 65; 5% take children; 0% are for women only and 0% for men only; 40% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Presbyopia studies take

Of 19 phase 3 interventional studies under Presbyopia, half reached primary completion within 10 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 26 mo4–8 · 13 studies——
Phase 310 mo7–11 · 19 studies——
Interventional, no phase10 mo3–23 · 129 studies6 mo2–19 · 87 studies15 mo7–23 · 42 studies
Observational11 mo5–24 · 35 studies—10 mo5–24 · 25 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 11, 2026.

Started recruiting2

Results posted1

Newly registered3

Studies

Recruiting first, then most recently updated. Showing 50 of 336. Browse all 336 → or search them.