Post-Traumatic Headache clinical trials
The registry lists 192 studies for Post-Traumatic Headache across more than 10 countries. 54 are recruiting or about to start. 160 of them are mainly about Post-Traumatic Headache (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Status
Who runs them
Riphah International University (18) · Cairo University (13) · Danish Headache Center (12) · Foundation University Islamabad (6) · Mayo Clinic (5) · University of Calgary (4) · St. Olavs Hospital (4) · University of Washington (4)
What is being tested here
Drugs under test in Post-Traumatic Headache studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Erenumab | 1 | 0 | 3 |
| Lidocaine | 1 | 0 | 2 |
| Islet Amyloid Polypeptide | 1 | 0 | 1 |
| Eptinezumab | 1 | 1 | 1 |
| Adrenomedullin | 1 | 0 | 1 |
| Steroids | 1 | 0 | 1 |
| BOTOX 200 | 1 | 1 | 1 |
| Prazosin | 0 | 0 | 2 |
| Sumatriptan | 0 | 0 | 2 |
| Metoclopramide | 0 | 1 | 2 |
Drug classes tested here Local anesthetics 1 open · Serotonin receptor agonists 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Jun 2027Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT) · Phase 3 · Sunnybrook Health Sciences Centre
- Nov 2026Physical Profile of Cervicogenic Headache: Comparison With Neck Pain and Healthy Controls · Istanbul Medipol University Hospital
- Dec 2026Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms · Walter Reed National Military Medical Center
- Dec 2026Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Knee Osteoarthritis(OA) · Beijing Tiantan Hospital
- Dec 2026Effect of Ultrasound-Guided Dry Needling Targeting Rectus Capitus Posterior Major on Individuals With Headaches · Texas Tech University Health Sciences Center
- Dec 2026Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Chronic Cervicogenic Headache · Beijing Tiantan Hospital
- Dec 2026Effect of Myofascial Release Technique Alone or Combined With Exercises on Cervical Cobb Angle, Sleep Quality, and Psychological Factors in Patients With Cervicogenic Headache · Al-Azhar University
- Dec 2026Effects of Graston Versus Myofascial Release Technique in Patients With Cervicogenic Headache · Riphah International University
- Dec 2026Comparative Effects of Post Isometric Relaxation and Reciprocal Inhibition in Individuals With Cervicogenic Headache. · Foundation University Islamabad
- Dec 2026Mulligan Technique Versus Proprioceptive Training in Cervicogenic Headache · Cairo University
Who these studies take
Of the 30 Post-Traumatic Headache studies recruiting now, 5 (17%) set no upper age limit and 24 (80%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (7%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 26 (87%) | 26 (87%) |
| 30 | 28 (93%) | 28 (93%) |
| 40 | 27 (90%) | 27 (90%) |
| 50 | 24 (80%) | 24 (80%) |
| 65 | 19 (63%) | 19 (63%) |
| 75 | 6 (20%) | 6 (20%) |
| 85 | 5 (17%) | 5 (17%) |
Across all 192 studies, recruiting or not: 80% stop at 75 or younger and 70% at 65; 6% take children; 3% are for women only and 1% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Post-Traumatic Headache studies take
Of 90 interventional studies with no phase under Post-Traumatic Headache, half reached primary completion within 12 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 12 mo5–26 · 90 studies | — | 11 mo5–26 · 89 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Started recruiting1
- Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT)Oct 29, 2026NCT07191145
Newly registered5
- Feasibility of Exercise and Transcranial Direct Current Stimulation for the Treatment of Post-traumatic HeadacheNov 10, 2026NCT07928492
- Trigger Point Injection and Myofascial Release for Cervicogenic HeadacheNov 2, 2026NCT07910877
- Comparative Effects of Dynamic Cupping and Facilitated Positional Release in Cervicogenic HeadacheNov 2, 2026NCT07911254
- Effects of Strain Counterstrain Versus Post Isometric Relaxation on Pain, Headache Frequency, and Quality of Life in Females With Cervicogenic Headache.Oct 27, 2026NCT07897695
- Mindful RAVANS StudyOct 14, 2026NCT07872761
Studies
Recruiting first, then most recently updated. Showing 50 of 192. Browse all 192 → or search them.
- Physical Profile of Cervicogenic Headache: Comparison With Neck Pain and Healthy ControlsRecruitingNCT077762751 country
- Comparative Effects of Dynamic Cupping and Facilitated Positional Release in Cervicogenic HeadacheNot yet recruitingNCT07911254Not applicable1 country
- Trigger Point Injection and Myofascial Release for Cervicogenic HeadacheNot yet recruitingNCT07910877Not applicable
- Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT)RecruitingNCT07191145Phase 31 country
- Mindful RAVANS StudyNot yet recruitingNCT07872761Not applicable
- Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Knee Osteoarthritis(OA)RecruitingNCT07347028Not applicable1 country
- Comparative Effects of Post Isometric Relaxation and Reciprocal Inhibition in Individuals With Cervicogenic Headache.RecruitingNCT07838545Not applicable1 country
- Mulligan Technique Versus Proprioceptive Training in Cervicogenic HeadacheNot yet recruitingNCT07832968Not applicable1 country
- Multisite Advancement of Research on Chronic Posttraumatic HeadacheRecruitingNCT05620719Not applicable1 country
- "Effectiveness of Kaltenborn Mobilization Techniques Versus Maitland Mobilization on Management of Cervicogenic HeadacheRecruitingNCT07820280Not applicable1 country
- Effect of Myofascial Release Technique Alone or Combined With Exercises on Cervical Cobb Angle, Sleep Quality, and Psychological Factors in Patients With Cervicogenic HeadacheRecruitingNCT07168512Not applicable1 country
- Effect of Ultrasound-Guided Dry Needling Targeting Rectus Capitus Posterior Major on Individuals With HeadachesRecruitingNCT07309874Not applicable1 country
- Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 2RecruitingNCT07796074Phase 21 country
- Osteopathic Care Combined With Physiotherapy and Pain Education for Cervicogenic HeadacheNot yet recruitingNCT07794319Not applicable1 country
- Manual Therapy vs. Multicomponent Exercise in Cervicogenic HeadacheNot yet recruitingNCT07776093Not applicable
- CORRELATION BETWEEN FORWARD HEAD POSTURE, CERVICAL MUSCLES ENDURANCE, AND PROPRIOCEPTIVE FUCTIONS IN CERVICOGENIC HEADACHE AMONG LATE ADOLESCENT STUDENTS.Not yet recruitingNCT077638861 country
- Effect of Mental Imagery in Patients With Persistent Post-concussion SymptomsRecruitingNCT07166536Not applicable1 country
- Exercise in Postconcussion Symptoms and Posttraumatic HeadacheRecruitingNCT06015451Not applicable1 country
- Effects of Graston Versus Myofascial Release Technique in Patients With Cervicogenic HeadacheNot yet recruitingNCT07724639Not applicable
- nVNS, CBD, and SoC for Persistent Post-Traumatic HeadacheNot yet recruitingNCT07624279Phase 21 country
- Ketamine, SGB and Combination Treatment for TBI-associated Headache or PTSDRecruitingNCT06608277Phase 21 country
- Osteopathic Manipulative Treatment vs Physiotherapy in Cervicocranial DysfunctionRecruitingNCT07555873Not applicable1 country
- Comparison of the Eficacy of Mulligan Mobilization and Myofascial Release in Patients With Cervicogenic HeadacheRecruitingNCT07508410Not applicable1 country
- Impact of Adding Instrument-assisted Soft Tissue Mobilization to Mulligan Therapy in Patients With Cervicogenic HeadacheNot yet recruitingNCT07373912Not applicable
- Effectiveness of Third Occipital Nerve Pulsed Radiofrequency in Cervicogenic HeadacheRecruitingNCT07366060Not applicable1 country
- Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Chronic Cervicogenic HeadacheRecruitingNCT07347730Not applicable1 country
- Hypersensitivity to Amylin in Post-Traumatic HeadacheNot yet recruitingNCT07340775Not applicable1 country
- Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress SymptomsRecruitingNCT05414708Not applicable1 country
- Mangement of Cervicogenic Headache by Maual TherapyEnrolling by invitationNCT07310823Not applicable1 country
- Behavior Therapy vs Education for Persistent Headache After Mild TBINot yet recruitingNCT07229391Not applicable1 country
- Therapeutic Efficacy of Different Wavelengths of Low-Level Laser Therapy in the Treatment of Cervicogenic HeadacheRecruitingNCT07163208Not applicable1 country
- Hypersensitivity to Adrenomedullin in Post-Traumatic HeadacheRecruitingNCT07059546Not applicable1 country
- Impact of Adding Integrated Neuromuscular Inhibition Technique to Postural Correction Exercises in Patients With Cervicogenic HeadacheNot yet recruitingNCT07086898Not applicable
- Comparing the Effects of Sub-Occipital Myofascial Release With and Without SNAG on People With Cervicogenic Dizziness.Not yet recruitingNCT07062809Not applicable1 country
- Efficacy of Adding Greater Occipital Nerve Block to Trigger Point Injection in Patients With Neck PainRecruitingNCT07058636Not applicable1 country
- Impact of Adding Jones Technique to Mulligan Therapy in Patients With Cervicogenic HeadacheNot yet recruitingNCT07047313Not applicable
- Comparison of Ventro-Cephalic to Dorso-Caudal Translatoric Glides in Management of Cervicogenic HeadacheRecruitingNCT07006454Not applicable1 country
- Manipulation and Dry Needling in Patients With Cervicogenic Headache and WAD IIRecruitingNCT06502951Not applicable1 country
- SPINEPASS: SPINE Self-management Techniques for Persistent Headache After Concussion: Physical Therapy Targeting Autonomic and Dura Mater Function.Not yet recruitingNCT06882239Not applicable1 country
- Ischemic Compression Technique Versus Jones Technique in Cervicogenic Headache PatientsRecruitingNCT06875869Not applicable1 country
- Muscle Function and Tenderness Differences in Headache PatientsEnrolling by invitationNCT068594631 country
- Safety and Efficacy of Botulinum Toxin A in Patients With Posttraumatic HeadacheRecruitingNCT06839118Phase 31 country
- Comparative Effects of Strain-counterstrain and Muscle Energy Techniques on Neck Pain and Functional Disability in Patients with Cervicogenic HeadacheNot yet recruitingNCT06811766Not applicable
- High Power Laser on Suboccipital Myoelectrical Activities and Quality of Life in Patients With Cervicogenic HeadacheNot yet recruitingNCT06803186Not applicable1 country
- Relation Between Cervicogenic Headache and Forward Head PostureRecruitingNCT047229131 country
- "Additional Effects of Sternocleidomastoid Release Along With Suboccipital Muscle Release in Management of Cervicogenic Headache'RecruitingNCT06731114Not applicable1 country
- Dry Needling Versus Dry Cupping on Pain and Disability in Cervicogenic Headache PatientsNot yet recruitingNCT06689371Not applicable
- Effects of Jones Technique and Cross Friction Massage on Cervicogenic Headache.Not yet recruitingNCT06452641Not applicable1 country
- Treatment of Acute PTH With a CGRP Receptor mAb in Military Service Members and Civilians With mTBIRecruitingNCT05049057Phase 21 country
- Frequency Specific Microcurrent Therapy for Mild Traumatic Brain InjuryNot yet recruitingNCT06245967Not applicable