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RecruitingNCT07006454Updated Jun 16, 2025

Comparison of Ventro-Cephalic to Dorso-Caudal Translatoric Glides in Management of Cervicogenic Headache

An interventional study of Ventro-Cephalic Translatoric Glide and Dorso-Caudal Translatoric Glide in Cervicogenic Headache, sponsored by Foundation University Islamabad. Recruiting at 1 site in Pakistan. Open to participants aged 18 Years to 44 Years. Per ClinicalTrials.gov, last updated 2025-06-16.

Sponsored by Foundation University Islamabad · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Jun 2025, 1 year 4 months ago, but the record still lists the study as recruiting.
  • Registered 10 months after the study started (first participant enrolled Jul 2024, registered May 2025).
  • Started Jul 2024; still recruiting 2 years 3 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
18 Years to 44 Years
Sex
All
01

Study summary

This study is a randomised control trial and the purpose of this study is to compare ventro-cephalic to dorso-caudal translatoric glides in management of cervicogenic headache.

Read the detailed description

Participants will be recruited into their respective groups using a coin toss method.Cervicogenic headache will be assesed using International Classification of Headache Disorders, 3rd edition:

A- Any headache fulling criterion C. B- Clinical and/or imaging evidence of lesion or disorder in cervical spine or soft tissues of neck that can cause headache.

C- Evidence of cause of headache demonstrated by at least 2 of these:

  1. headache has developed in temporal relation to the onset of the cervical disorder or lesion.
  2. headache has significantly improved or resolved in parallel with improvement in cervical lesion or disorder.
  3. cervical range of motion is reduced, and headache is made significantly worse by provocative maneuvers.
  4. headache is abolished following anaesthetic blocked of cervical structure. D- Not better accounted for by another ICHD-3 diagnosis.

CEH subject selection is based on clinical criteria, however anaesthetic blockades is not used as a criterion.

02

Conditions studied

  • Cervicogenic Headache
03

In context

Post-Traumatic Headache

192 studies on the registry are indexed under Post-Traumatic Headache; 54 are open to participants now.

This study's planned enrollment of 40 is close to the median of 44 across 169 interventional studies indexed under Post-Traumatic Headache.

Browse Post-Traumatic Headache studies →

Lead sponsor

Foundation University Islamabad is the lead sponsor of 255 studies on the registry; 142 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 44 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

    • Age 18 to 44 years old

      • Both male and female A- Any headache fulling criterion C. B- Clinical and/or imaging evidence of lesion or disorder in cervical spine or soft tissues of neck that can cause headache.

C- Evidence of cause of headache demonstrated by at least 2 of these:

  1. headache has developed in temporal relation to the onset of the cervical disorder or lesion.
  2. headache has significantly improved or resolved in parallel with improvement in cervical lesion or disorder.
  3. cervical range of motion is reduced, and headache is made significantly worse by provocative maneuvers.
  4. headache is abolished following diagnostic blocked of cervical structure. D- Not better accounted for by another ICHD-3 diagnosis

Exclusion criteria

Exclusion Criteria:

  • 1- Tension-type headaches and migraine 2- History of Vertigo or Dizziness 3- Already taking manual therapy treatment 4- Prior surgery to the head and neck 5- Trauma
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
40 participants (estimated)

Study arms

  • Experimental
    Group A

    Participants of group A will receive ventro-cephalic translatoric glide, total of 3 sets with 15 repetitions per set. Duration (5 treatment sessions per week for 2 weeks)

    Procedure: Ventro-Cephalic Translatoric Glide

  • Experimental
    Group B

    Participants of group B will receive Dorso-caudal translatoric glide, total of 3 sets with 15 repetitions per set. Duration (5 treatment sessions per week for 2 weeks)

    Procedure: Dorso-Caudal Translatoric Glide

Interventions

  • ProcedureVentro-Cephalic Translatoric Glide

    Participants of group A will receive ventro-cephalic translatoric glides, total of 3 sets with 15 repetitions per set. PROCEDURE: 1. Patient sits on low chair with back straight and therapist stand facing the patient's right side. 2. Therapist's stable hand: with the thumb and index finger of left hand fixate caudal vertebra. 3. Therapist's moving hand: therapist will place his/her right hand on left side of patient's head and cervical spine than place little finger around cranial vertebra of segment to be moved. 4. Apply glide in ventro-cranial direction in the right angle of the treatment plane of the facet joint.

  • ProcedureDorso-Caudal Translatoric Glide

    Participants of group B will receive Dorso-caudal translatoric glides, total of 3 sets with 15 repetitions per set. PROCEDURE: 1. Patient sits on low chair with back straight and therapist stand facing the patient's left side. 2. Therapist's stable hand: with the thumb and index finger of right hand fixate caudal vertebra. 3. Therapist's moving hand: therapist will place his/her left hand on right side of patient's head and cervical spine than place little finger around cranial vertebra of segment to be moved. 4. Apply glide in dorso-caudal direction in the right angle of the treatment plane of the facet joint.

06

What researchers measure

Primary outcomes

  1. Headache intensity

    It will be measured on a numeric pain rating scale where participant select number ranging from 0 to 10 based on pain intensity, with 0 representing no pain and 10 denotes extreme pain.

    Time frame: Variable will be evaluated at baseline and then weekly for next 2 weeks.

  2. Headache disability

    It will be measured using headache disability index (HDI) which is a 25 item self-rated questionnaire in which participants rate their headache disability by selecting an option from 1 to 3 (yes= 4 points, sometimes= 2 points, and No = 0 point) then sum of responses is used to get final score. Interpretation: 10 to 28= mild disability 30 to 48= moderate disability 50 to 68= severe disability 72 or more= complete disability

    Time frame: Variable will be evaluated at baseline and then weekly for next 2 weeks

  3. Quality of Life of patient

    It will be measured using headache impact test (HIT-6), this tool is used to measure impact of headache on ability to function, a 6 items self-rated questionnaire in which participant select an option from 1 to 5 (Never= 6 points, rarely= 8, sometimes= 10, very often= 11, always= 13) then sum of responses is used to get final score. Interpretation: 60 or more= Very severe impact 56 to 59= Substantial impact 50 to 55= Some impact 49 or less= Little or no impact

    Time frame: Variable will be evaluated at baseline and then weekly for next 2 weeks

  4. Headache Frequency

    It will be measured using medical diary, which is a self-reported measure in which the patient will be asked to report the number of headache days per week through a medical logbook, which will be recorded every day and night.

    Time frame: Variable will be evaluated at baseline and then weekly for next 2 weeks

  5. Cervical range of motion

    It will be measured using CROM instrument a plastic frame device that is fastened to the head with help of Velcro-strap, it consist of 3 separate inclinometers that are fixed to frame (1 in sagittal plan which evaluates range of motion in flexion and extension, where 2nd in frontal plane which evaluates range of motion in side bending, and 3rd in horizontal plan which indicates range of motion in rotation)

    Time frame: Variable will be evaluated at baseline and then weekly for next 2 weeks

  6. Cervical flexion rotation test

    It is used to evaluate impairment of cervical function as the diagnostic criterion of internation headache society (IHS) consist of subjective feathers which includes impairments at atlanto-axial motion segments which is assessed by cervical flexion rotation test.

    Time frame: Variable will be evaluated at baseline and then weekly for next 2 weeks

07

Study locations

1 of 1 sites recruiting
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Jul 2024 (actual). Primary completion is estimated for Jun 2025, 11 months after the start.

Of 89 non-industry interventional studies with no phase under Post-Traumatic Headache, half reached primary completion within 11 months of starting (the median), counting those still running; a quarter within 5 and three quarters within 26. This study's planned 11 months is close to that.

Counting every sponsor, half of 90 studies reached it within 12 months; a quarter within 5 and three quarters within 26.

How these figures are worked out, and which studies are left out of them.

Registered
May 28, 2025
First posted
Jun 5, 2025
StartActual
Jul 18, 2024
Primary completionEst.
Jun 20, 2025
CompletionEst.
Jun 20, 2025
Last update
Jun 16, 2025
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jun 16, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT07006454
Responsible party
Sponsor
First posted
Jun 5, 2025
Start date
Jul 18, 2024
Primary completion
Jun 20, 2025 (estimated)
Completion
Jun 20, 2025 (estimated)
Last update
Jun 16, 2025

Study contacts

Aeysha Bibi, DPT
Contact
ayeshaaltaf604@gmail.com
+923058766593

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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