Cairo University: Periapical Periodontitis trials

The registry lists 22 Periapical Periodontitis studies with Cairo University as lead sponsor. 7 are open to participants now and 0 have results posted.

Early Phase 1 3Phase 1 2Phase 2 1Phase 3 1No phase 16(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Apical Periodontitis and Glycemic Control in Diabetic and Non-diabetic Egyptian Sub-populationNot yet recruitingNCT07856186
• The Effect of Different Intra-canal Medications on Postoperative PainRecruitingNCT07603934Early Phase 1
• Effect of Bio-C Temp Versus Calcium Ydroxide as Intracanal Dressings on Postoperative Pain Intensity and Periapical MMP-9 Level in Patients With Necrotic PulpNot yet recruitingNCT07101029Early Phase 1
• The Effect of Photobiomodulation Using Low-Level Diode Laser Therapy on Postoperative Pain in Symptomatic Lower Molar Teeth With Irreversible Pulpitis and Apical Periodontitis; a Randomized Controlled Clinical TrialNot yet recruitingNCT06396130Not applicable
• Clinical and Radiographic Success of Regeneration Using Injectable Platelet Rich FibrinNot yet recruitingNCT06086249Not applicable
• Evaluation of Nano Bioactive Glass Combined With i-PRF Scaffold in Vital Pulp TreatmentsRecruitingNCT05902936Not applicable
• Effect of Injectable Platelet Rich Fibrin Augmented With Vitamin C Compared to Injectable Platelet Rich Fibrin Alone on Healing of Necrotic Mature Single Rooted Teeth With Chronic Peri-apical Periodontitis Following Regenerative Endodontics (A Randomized Controlled Trial)Not yet recruitingNCT05585359Not applicable
• Expression of IL-8 Before and After Root Canal Treatment in Patients With Symptomatic Apical PeriodontitisCompletedNCT05653947Not applicable
• Effect of Diclofenac Sodium Versus Calcium Hydroxide as Intracanal Medication on the Intensity of Postoperative Pain, Bacterial Load Reduction and MMP-9 Levels in Patients With Necrotic Pulp.Status unknownNCT05582421Early Phase 1
• Effect of Simvastatin Versus Calcium Hydroxide Intracanal Medications on Post-operative Pain and Interleukin 6 and 8CompletedNCT05525013Not applicable
• Evaluation of Post-operative Pain and Expression of IL-8 Using Ketolac or Cryoirrigation as a Final Flush in Single Visit Endodontic Treatment in Teeth With Symptomatic Irreversible Pulpitis and Apical Periodontitis.Randomized Clinical Trial.CompletedNCT04733326Phase 1
• Healing Potentiality Of Blood Clot S-PRF and A-PRF in the Treatment Of Necrotic Mature Single-Rooted Teeth With Chronic Peri-Apical PeriodontitisCompletedNCT04606719Not applicable
• Effect of Low-level Laser Therapy Versus Calcium Hydroxide Intracanal Medication on Postoperative Pain and Substance P Levels in Patients With Symptomatic Apical PeriodontitisStatus unknownNCT04594317Not applicable
• Ketorolac Irrigant on Post Operative PainStatus unknownNCT04319549Not applicable
• Regenerative Endodontic Treatment of Mature Necrotic Teeth With Apical PeriodontitisCompletedNCT04018456Not applicable
• Pain After PRP Revascularization and Endodontic Treatment of Non-vital Mandibular Molars With Apical PeriodontitisStatus unknownNCT03350841Not applicable
• Effect of Occlusal Reduction on Post-operative PainStatus unknownNCT03189771Not applicable
• Effect of Preoperative Clindamycin on Postoperative Endodontic PainStatus unknownNCT03033472Phase 2/3
• Effect of Preoperative Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic PainCompletedNCT03033147Not applicable
• Effect of Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic PainStatus unknownNCT03007342Not applicable
• Single Versus Multiple Visits Endodontic TreatmentCompletedNCT02947763Phase 1
• Effect of Passive Ultrasonic Irrigation Versus Needle Irrigation on Postoperative Pain and Periapical HealingStatus unknownNCT02913937Not applicable