Drug
Sodium Hypochlorite clinical trials
Also written Dakin's solution.
- studies test it
- 22
- open now
- 5
- in phase 3
- 2
- first study started
- 2005
Keep track of what changes. Save the Sodium Hypochlorite studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Other names
Combined with it in one product
Studies by the year they started
22 studies that test it; most in 2025 (4)
| Year | Studies |
|---|---|
| 2005 | 1 |
| 2011 | 1 |
| 2014 | 3 |
| 2015 | 1 |
| 2020 | 3 |
| 2021 | 3 |
| 2022 | 1 |
| 2023 | 2 |
| 2024 | 1 |
| 2025 | 4 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 3
- Phase 2
- 2
- Phase 3
- 2
- Phase 4
- 4
- No phase
- 10
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 22
Stanford University (2) · National and Kapodistrian University of Athens (1) · CMH Multan Institute of Medical Sciences (1) · Armed Forces Institute of Dentistry, Pakistan (1) · University of Sulaimani (1) · Dow University of Health Sciences (1) · Altamash Institute of Dental Medicine (1) · King Abdulaziz University (1)
Often tested with
Tested in the same studies.
Hydrogen Peroxide (2) · Chlorhexidine (1) · Etidronic Acid (1) · Maleic acid (1) · Polihexanide (1) · Povidone-Iodine (1) · Cetylpyridinium (1) · 70% Ethyl Alcohol (1)
Studies
Open first, then newest update. How each study uses Sodium Hypochlorite is read from its arms, and is right about nine times in ten.
Testing it · 22
- Influence of Irrigant Delivery Systems on the Incidence of Postoperative Discomfort in Oval CanalsRecruitingNot applicableMinia UniversityNCT07788027Written as Sodium hypochlorite 5.25%
- Effect Of Different Sodium Hypochlorite Concentrations On Intracanal Substance P, CGRP And Opiorphin Levels And Postoperative Pain During Root Canal RetreatmentRecruitingNot applicableKEZBAN MELTEM ÇOLAKNCT07453576Written as Sodium Hypochlorite 1% Irrigation
- Comparing Two Root Canal Cleaning Solutions (Chlorhexidine vs. Sodium Hypochlorite) for Pain After TreatmentNot yet recruitingNot applicableCollege of Physicians and Surgeons PakistanNCT07453160Written as Sodium hypochlorite 5.25%
- Chitosan Irrigation in Premolar Root Canal Therapy (Randomized Trial)RecruitingNot applicableESRA DAĞCINCT07048028Written as Sodium Hypochlorite
- Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary MolarsNot yet recruitingNot applicableCairo UniversityNCT06971055Written as Sodium hypochlorite
- Comparison of Post-Operative Endodontic Pain Using Sodium Hypochlorite, Hydrogen Peroxide, and Normal Saline as Root Canal IrrigantsCompletedNot applicableCMH Multan Institute of Medical SciencesNCT07486245Written as Sodium Hypochlorite 2.5%
- Clinical Investigation of Chemomechanical Parameters for an Efficient Disinfection of the Root CanalActive, not recruitingNot applicableNational and Kapodistrian University of AthensNCT06949176Written as Sodium Hypochlorite.
- Comparison of Effectiveness of DisinfectantsCompletedPhase 1Armed Forces Institute of Dentistry, PakistanNCT06811779Written as Sodium Hypochlorite
- Lasers as an Alternative to Formocresol and Sodium Hypochlorite Medicaments in Pulpotomy TechniquesCompletedPhase 4University of SulaimaniNCT06002646Written as Sodium Hypochlorite Solution
- Modified Dakin's Solution in Reducing Radiation-Induced Dermatitis in Patients With Head and Neck Cancer Undergoing Radiation TherapyCompletedPhase 3Stanford UniversityNCT02369835Written as Dakin's solution
- Comparing Different Single and Combination Chelating Agents on Sealer Penetration and Dentin Erosion.CompletedNot applicableDow University of Health SciencesNCT05778227Written as Etidronic acid /sodium hypochlorite
- Comparison of Antimicrobial Action of Sodium Hypochlorite and Polyhexamethylene Biguanide as Root Canal IrrigantsCompletedPhase 2Altamash Institute of Dental MedicineNCT05306431Written as Sodium Hypochlorite
- The Efficacy of Pre-procedural Mouth Rinses on COVID-19 Saliva Viral LoadCompletedPhase 4King Abdulaziz UniversityNCT04721457Written as 0.1% Sodium Hypochlorite
- Evaluation of Postoperative Pain With Eddy Tips (EPPET)CompletedNot applicableUniversidade do PortoNCT03946306Written as 5,25% NaOCl with syringe needle irrigation alone
- Dilute Bleach Compresses for Radiation DermatitisWithdrawnEarly Phase 1Dana-Farber Cancer InstituteNCT04851522Written as Di-Dak-Sol
- Estimation of the Incidence of Colonization of Peripheral Venous Catheters After Skin Disinfection With 0.5% Sodium Hypochlorite, Preceded or Not by an Application of 70% EthanolCompletedPhase 4Poitiers University HospitalNCT04391660Written as 0.5% sodium hypochlorite solution
- Evaluation of Post Operative Pain in Retreatment of Molars Using Different IrrigantStatus unknownPhase 1Tamil Nadu Dr.M.G.R.Medical UniversityNCT04250519Written as Sodium Hypochlorite
- Reducing Bacteria That Cause Tooth DecayCompletedPhase 3University of California, Los AngelesNCT03062605Written as NaOCL
- Bleach Bath Treatment of Adults With Atopic DermatitisCompletedNot applicableUniversity of RochesterNCT01996150Written as bleach bath (sodium hypochlorite)
- Dakin's Solution in Preventing Radiation Dermatitis in Patients With Breast Cancer Undergoing Radiation TherapyCompletedPhase 2Stanford UniversityNCT02203565Written as Dakin's solution
See all 22 studies that test Sodium Hypochlorite →
Given in every arm · 4 — Sodium Hypochlorite is usual care beside what is tested
- Effect of Enamel Cleaning on a Remineralizing Paste for Hypomineralizated LesionsNot yet recruitingNot applicableUniversidade CeumaNCT07653373Written as Sodium hypochlorite 5.25%
- Estimate the Effect of aPDT on Root Canal DisinfectionStatus unknownNot applicableFujian Medical UniversityNCT02929927Written as 2.5%NaClO
- Treatment of Young Permanent Teeth With Different Adjuvant ApproachesCompletedNot applicableUniversity of BelgradeNCT05291195Written as Sodium hypochlorite group
- Application of Photodynamic Therapy and Diode Laser for Endodontic Therapy of Young Permanent TeethCompletedPhase 2Association of Paediatric and Preventive Dentists of SerbiaNCT03074136Written as 0.5% Sodium hypochlorite
As the comparator · 11 — what is tested is compared with Sodium Hypochlorite
- Comparing Amla (Emblica Officinalis) and 3% Sodium Hypochlorite Against Enterococcus Faecalis in Root Canal Treatment.Not yet recruitingNot applicablePostgraduate Medical Institute, LahoreNCT07688005Written as Sodium Hypochlorite 3% Solution
- Frankincense Versus Sodium Hypochlorite for Root Canal DisinfectionNot yet recruitingEarly Phase 1Oman Dental CollegeNCT07823868Written as Sodium hypochlorite 3%
- Evaluation of Moringa Oleifera Leaf Extract Versus Sodium Hypochlorite in Pulpectomy of Nonvital Primary MolarsNot yet recruitingNot applicableCairo UniversityNCT06948526Written as Sodium Hypochlorite 1%
- A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm TreatmentCompletedPhase 4University of PennsylvaniaNCT06110494Written as NaOCl
- Role of Propolis Endodontic Irrigant on Post-Operative PainCompletedPhase 3Dow University of Health SciencesNCT05974748Written as Sodium hypochlorite 5.25%
- Effect of Moringa Oleifera Leaf Extract on Postoperative Pain and Bacterial Reduction in Mandibular PremolarsStatus unknownPhase 2/3Cairo UniversityNCT05348824Written as Sodium hypochlorite
- Effect of Propolis Nanoparticles on Postoperative Pain and Bacterial Reduction in Mandibular PremolarsStatus unknownPhase 2/3Cairo UniversityNCT05146713Written as sodium hypochlorite
- Effect of Irrigation With Antibiotic-containing Solutions on Postoperative Pain and Intra-canal BacteriaStatus unknownPhase 4Cairo UniversityNCT04035070Written as 2.5% sodium hypochlorite
- Effect of Etidronate in Sodium Hypochlorite Versus Sodium Hypochlorite on the Intensity of Postoperative PainStatus unknownNot applicableCairo UniversityNCT04035330Written as sodium hypochlorite
- Effect of Neem and NaOCl on Postoperative Pain and Amount of EndotoxinsStatus unknownNot applicableCairo UniversityNCT03312153Written as 2.5% sodium hypochlorite
- Assessment of Pain and Antibacterial Activity of Chitosan Versus Sodium Hypochlorite as Irrigant in Infected CanalStatus unknownPhase 2/3Cairo UniversityNCT03719261Written as Sodium Hypochlorite
Codes
What other systems call Sodium Hypochlorite · ClinicalTrials.gg INT008214
- MeSH (NLM) D012973Sodium HypochloriteConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) DY38VHM5ODSODIUM HYPOCHLORITEConfirmed FDA, NLM, Wikidata
- RxNorm 9881Confirmed FDA, Wikidata
- Wikidata Q407204sodium hypochloriteConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C80658Sodium HypochloriteOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D012973 | Sodium Hypochlorite | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | DY38VHM5OD | SODIUM HYPOCHLORITE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 9881 | — | Confirmed FDA, Wikidata |
| Wikidata | Q407204 | sodium hypochlorite | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C80658 | Sodium Hypochlorite | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.