Drug
Metronidazole clinical trials
Also written Flagyl and MetroGel.
- studies test it
- 227
- open now
- 25
- in phase 3
- 40
- first study started
- 1995
Keep track of what changes. Save the Metronidazole studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
- Flagyl
- 37
Development codes
Studies by the year they started
227 studies that test it; most in 2021 (18)
| Year | Studies |
|---|---|
| 1995 | 1 |
| 2001 | 1 |
| 2002 | 4 |
| 2003 | 4 |
| 2004 | 3 |
| 2005 | 5 |
| 2006 | 11 |
| 2007 | 4 |
| 2008 | 5 |
| 2009 | 5 |
| 2010 | 12 |
| 2011 | 16 |
| 2012 | 7 |
| 2013 | 11 |
| 2014 | 7 |
| 2015 | 15 |
| 2016 | 10 |
| 2017 | 8 |
| 2018 | 14 |
| 2019 | 15 |
| 2020 | 13 |
| 2021 | 18 |
| 2022 | 5 |
| 2023 | 7 |
| 2024 | 9 |
| 2025 | 11 |
| 2026 | 6 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 4
- Phase 1
- 20
- Phase 2
- 48
- Phase 3
- 40
- Phase 4
- 83
- No phase
- 45
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 42 · Other 185
Shanghai Jiao Tong University School of Medicine (9) · Pfizer (8) · Helsinki University Central Hospital (4) · Galderma R&D (4) · S.L.A. Pharma AG (4) · HaEmek Medical Center, Israel (3) · Merck Sharp & Dohme LLC (3) · University of Alabama at Birmingham (3)
Often tested with
Tested in the same studies.
Amoxicillin (36) · Clarithromycin (26) · Ciprofloxacin (17) · Tetracycline (16) · Esomeprazole (15) · Bismuth tripotassium dicitrate (10) · Minocycline (9) · Bismuth (9)
Studies
Open first, then newest update. How each study uses Metronidazole is read from its arms, and is right about nine times in ten.
Testing it · 227
- Comparative Efficacy of Amoxicillin, Metronidazole, and Chlorhexidine in Preventing Alveolar OsteitisNot yet recruitingNot applicableKhyber Medical University PeshawarNCT07833176Written as Metronidazole
- Comparison of Postoperative Pain After Double Antibiotic Paste vs Calcium Hydroxide in Teeth With Symptomatic Apical PeriodontitisRecruitingNot applicableCollege of Physicians and Surgeons PakistanNCT07867951Written as Double Antibiotic Paste
- Trial Utilizing Metronidazole to Optimize the Microbiome of Rectal Adenocarcinoma Undergoing Neoadjuvant TherapyRecruitingPhase 2M.D. Anderson Cancer CenterNCT06569368Written as Metronidazole
- Antibiotics After Incision and Drainage to Prevent Fistula Formation After First Episode of Perianal AbscessNot yet recruitingPhase 4University of Illinois at ChicagoNCT07704359Written as Ciprofloxacin + Metronidazole
- AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm BirthNot yet recruitingPhase 3Assistance Publique Hopitaux De MarseilleNCT06349122Written as Metronidazole
- Comparative Efficacy of Antibiotics for Small Intestine Bacterial Overgrowth in Bangladeshi ChildrenRecruitingPhase 2University of VirginiaNCT07451171Written as Metronidazole
- Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral CancerRecruitingPhase 2Case Comprehensive Cancer CenterNCT06627270Written as Metronidazole
- Chlorhexidine and/or Metronidazole Plus FB301 Pre-treatment TrialRecruitingPhase 2Freya Biosciences ApSNCT07481955Written as metronidazole 500 mg
- Effect of Triple Versus Quadruple Therapy for Treating Helicobacter Pylori InfectionEnrolling by invitationNot applicableAkil Al IslamNCT07010744Written as Quadruple therapy
- Refining Treatment Options for Trichomonas Vaginalis Infection: A Comparative Analysis of Metronidazole and SecnidazoleRecruitingPhase 4Tulane UniversityNCT06261840Written as Metronidazole 500 mg
- Comparing Two Medicines for Healing Jaw Bone Infections After Root Canal TreatmentNot yet recruitingNot applicableFaiz ur rahmanNCT07239739Written as Triple Antibiotic Paste
- Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)RecruitingPhase 4Ohio State UniversityNCT06396078Written as Metronidazole 500 mg
- Efficacies of Bismuth-amoxicillin-vonoprazan Triple Therapy and Bismuth Quadruple TherapyRecruitingNot applicableKaohsiung Medical UniversityNCT07358130Written as rabeprazole, tripotassium dicitrate bismuthate, tetracycline, metronidazole
- A "Screen and Treat" Helicobacter Pylori Eradication Trial in Adolescents in Three Regions of ChileRecruitingNot applicableMiguel O'Ryan GallardoNCT05926804Written as Metronidazole
- Metronidazole as Preoperative Therapy in CRC / FusoMetro-001RecruitingPhase 2Oncology Institute of Southern SwitzerlandNCT05748145Written as Metronidazole Oral
- Pharmacokinetic and Safety Study of Metronidazole Oral Suspension in Pediatric Patients With Anaerobic Bacterial InfectionNot yet recruitingPhase 2Saptalis Pharmaceuticals LLCNCT07146217Written as Likmez® (metronidazole) Oral Suspension
- ORal Antibiotics in Acute Mesenteric IschemiaRecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT06387147Written as Metronidazole
- Intralesional Injection of Metronidazole for the Management of Cutaneous LeishmaniasisRecruitingPhase 2Hayder Adnan FawziNCT06798415Written as Metronidazole
- Intestinal Microbiome Modulation With Antibiotics in the Neoadjuvant Treatment of Locally Advanced Rectal CancerRecruitingPhase 2AC Camargo Cancer CenterNCT06793137Written as Metronidazole
- Optimal Duration of Bismuth Quadruple Therapy for Helicobacter Pylori Eradication in Females As Compared with MalesEnrolling by invitationPhase 4National Cheng-Kung University HospitalNCT06509139Written as Metronidazole 250 MG
See all 227 studies that test Metronidazole →
Given in every arm · 42 — Metronidazole is usual care beside what is tested
- Photobiomodulation With Blue LED in Recurrent Bacterial VaginosisNot yet recruitingNot applicablePatricia LordeloNCT07835815Written as Metronidazole
- Vaginal Microbiota TransplantRecruitingPhase 1/2Douglas KwonNCT04046900Written as Oral Metronidazole
- MOTIF@FRESH: Modifying Organisms Transvaginally in Females @ FRESHNot yet recruitingPhase 2Douglas KwonNCT07566754Written as oral metronidazole
- Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate CancerRecruitingPhase 2Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT06616597Written as Metronidazole
- Combination Study of Antibiotics With Enzalutamide (PROMIZE)RecruitingPhase 1/2Institute of Cancer Research, United KingdomNCT06126731Written as Metronidazole 400mg
- Optimization of Bacterial Vaginosis Treatment in Women of Reproductive AgeRecruitingPhase 4I.M. Sechenov First Moscow State Medical UniversityNCT06458543Written as Metronidazole 500 mg
- Doxycycline for Helicobacter Pylori Rescue TreatmentRecruitingPhase 4Shanghai Jiao Tong University School of MedicineNCT05874570Written as Metronidazole
- Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic CancerRecruitingPhase 2Icahn School of Medicine at Mount SinaiNCT05462496Written as Metronidazole
- Vonoprazan-containing Triple Therapy Versus Empiric Bismuth Quadruple Therapy for First-line Helicobacter Pylori Treatment: a Randomized Clinical TrialNot yet recruitingPhase 4Shanghai East HospitalNCT05726734Written as Amoxicillin, Metronidazole
- Susceptibility-Guided Therapy for Helicobacter Pylori Infection TreatmentWithdrawnPhase 4Shanghai Zhongshan HospitalNCT05250050Written as Metronidazole
- Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-respondersActive, not recruitingPhase 2M.D. Anderson Cancer CenterNCT04729322Written as Metronidazole
- Metronidazole SC Penetrance With MoisturizersCompletedNot applicableDuke UniversityNCT06434519Written as Metronidazole cream
- Helicobacter Pylori Eradication StudyCompletedPhase 4Inje UniversityNCT03130452Written as Metronidazole 500 mg
- Vaginal lIve Biotherapeutic RANdomized TrialCompletedEarly Phase 1Massachusetts General HospitalNCT06135974Written as Metronidazole Oral
- Preoperative Oral Antibiotics With vs Without Mechanical Bowel Preparation to Reduce Surgical Site Infections Following Colonic Resection: an International Randomized Controlled Trial.Status unknownPhase 4Hospital Universitari Vall d'Hebron Research InstituteNCT04161599Written as Metronidazole 250 MG Oral Tablet [Flagyl]
- Safety and Efficacy of Vaginal Microbiota Transplant (VMT) in Women With Bacterial Vaginosis (BV)WithdrawnPhase 1Johns Hopkins UniversityNCT03769688Written as Metronidazole gel
- Tetracycline Versus Doxycycline for HP Rescue TherapyStatus unknownPhase 4Shanghai Zhongshan HospitalNCT05018923Written as Metronidazole
- Non-invasive Test-guided Tailored Therapy Versus Empiric Treatment for Helicobacter Pylori Infection.Status unknownPhase 3University of BariNCT04107194Written as Metronidazole
- Bismuth-Metronidazole Triple Therapy for H. Pylori First-line TreatmentStatus unknownPhase 4Shanghai Zhongshan HospitalNCT04667299Written as Metronidazole
- Determine the PK and Safety and Tolerability of ATM-AVI for the Treatment of cIAIs in Hospitalized Adults (REJUVENATE)CompletedPhase 2PfizerNCT02655419Written as Metronidazole
Showing 20 of 42.
As the comparator · 71 — what is tested is compared with Metronidazole
- Piperacillin/Tazobactam Versus Ceftriaxone and Metronidazole for Children With Perforated AppendicitisNot yet recruitingPhase 3McMaster Children's HospitalNCT07869095Written as Ceftriaxone + Metronidazole
- APLAUD Trial (Antibiotics vs PLacebo for Acute Uncomplicated Diverticulitis)RecruitingPhase 2Vanderbilt University Medical CenterNCT07492134Written as Metronidazole
- Silver Nanoparticle-Reinforced Double Antibiotic Paste in Symptomatic Apical Periodontitis: A Randomized Controlled TrialNot yet recruitingNot applicableAll India Institute of Medical SciencesNCT07762599Written as Double Antibiotic Paste
- Metronidazole- Versus Tinidazole-Based Bismuth Quadruple Therapy for Helicobacter Pylori EradicationNot yet recruitingNot applicableUniversity of Medicine and Pharmacy at Ho Chi Minh CityNCT07746934Written as Metronidazole
- Revascularization of Young Immature Permenant Teeth Using Different Types of Intra Canal MedicationNot yet recruitingNot applicableAl-Azhar UniversityNCT07236567Written as Triple Antibiotic Paste
- Gut Decolonisation With Neomycin/Metronidazole or Rifaximin Before Colon SurgeryNot yet recruitingPhase 4Universität LuzernNCT07180615Written as Metronidazole
- Study to Assess the Efficacy and Safety of Meropenem and Pralurbactam in CIAINot yet recruitingPhase 3Qilu Pharmaceutical Co., Ltd.NCT06633718Written as Metronidazole
- Antibiotic Prophylaxis in Metabolic Bariatric SurgeryNot yet recruitingNot applicableGeneral Committee of Teaching Hospitals and Institutes, EgyptNCT06510452Written as 500 mg of Metronidazole IV
- Study of Nitazoxanide (NTZ) for Helicobacter Pylori in ChildrenRecruitingPhase 3Tanta UniversityNCT04415983Written as Metronidazole
- Pharmacokinetics of Transdermal MetronidazoleActive, not recruitingPhase 4University of IowaNCT05929794Written as Metronidazole 0.75% Topical Gel
- Bismuth Quadruple Therapy Versus Modified Bismuth Therapy for Helicobacter PyloriCompletedPhase 3Reham Abdelkader ElkhoulyNCT07810985Written as Quadruple therapy
- Non-antibiotic Management in Acute Uncomplicated DiverticulitisWithdrawnPhase 4Montefiore Medical CenterNCT07625267Written as Ciprofloxacin plus metronidazole
- Nitazoxanide vs Metronidazole for Entamoeba Diarrhea in ChildrenCompletedPhase 2University of Child Health Sciences and Children's Hospital, LahoreNCT07790926Written as Metronidazole
- Piperacillin/Tazobactam Versus ceftriAxone and Metronidazole for Children With Perforated Appendicitis (ALPACA)CompletedPhase 2McMaster Children's HospitalNCT05943223Written as Metronidazole Injection
- Fourteen-Day Vonoprazan-Based Dual Therapy With Amoxicillin as First-Line Helicobacter Pylori Treatment in Comparison With Extended Sequential TherapyCompletedPhase 4Fu Jen Catholic University HospitalNCT06156085Written as Lansoprazole, Amoxicillin, Clarithromycin and Metronidazole
- Comparison of the Effects of N-acetylcysteine, Calcium Hydroxide, and Double Antibiotic PasteCompletedNot applicableAtaturk UniversityNCT07340944Written as Double Antibiotic Paste
- Study of Metronidazole Delayed-Release Capsules in Comparison With Immediate-Release Tablets (Flagyl) for Safety and PharmacokineticsCompletedPhase 1Gateway Pharmaceutical LLCNCT07251127Written as Immediate-release metronidazole
- Rescue Therapy for Helicobacter Pylori InfectionCompletedPhase 4Shanghai Jiao Tong University School of MedicineNCT05874544Written as Metronidazole
- Anti-protozoal Effect of Steroid Hormone 20-hydroxyecdysoneActive, not recruitingPhase 2/3Research Institute of Epidemiology, Microbiology and Infectious Diseases, UzbekistanNCT04827537Written as Metronidazole Oral
- Comparison of Dequalinium Chloride (Fluomizin) vs Oral Metronidazole for the Treatment of Bacterial VaginosisTerminatedPhase 4Medinova AGNCT05788991Written as Metronidazole Oral
Showing 20 of 71.
Codes
What other systems call Metronidazole · ClinicalTrials.gg INT007828
- MeSH (NLM) D008795MetronidazoleConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 140QMO216EMETRONIDAZOLEConfirmed FDA, NLM, Wikidata
- RxNorm 6922Confirmed FDA, Wikidata
- Wikidata Q169569metronidazoleConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C651MetronidazoleOne source FDA
- DrugBank DB00916One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D008795 | Metronidazole | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 140QMO216E | METRONIDAZOLE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 6922 | — | Confirmed FDA, Wikidata |
| Wikidata | Q169569 | metronidazole | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C651 | Metronidazole | One source FDA |
| DrugBank | DB00916 | — | One source Wikidata |
Also registered as metronidazole hydrochloride (UNII 76JC1633UF · RxNorm 82047) and metronidazole phosphate (UNII L500PR95QA).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.