Drug
Zoledronic Acid clinical trials
Also written Zometa, Zoledronate, Aclasta and ZOL446.
- studies test it
- 272
- open now
- 16
- in phase 3
- 94
- first study started
- 1998
Keep track of what changes. Save the Zoledronic Acid studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Other names
Combined with it in one product
Studies by the year they started
272 studies that test it; most in 2005 (29)
| Year | Studies |
|---|---|
| 1998 | 1 |
| 1999 | 2 |
| 2000 | 3 |
| 2001 | 5 |
| 2002 | 15 |
| 2003 | 20 |
| 2004 | 25 |
| 2005 | 29 |
| 2006 | 26 |
| 2007 | 11 |
| 2008 | 17 |
| 2009 | 19 |
| 2010 | 9 |
| 2011 | 8 |
| 2012 | 12 |
| 2013 | 4 |
| 2014 | 2 |
| 2015 | 7 |
| 2016 | 8 |
| 2017 | 6 |
| 2018 | 6 |
| 2019 | 6 |
| 2020 | 4 |
| 2021 | 7 |
| 2022 | 3 |
| 2023 | 6 |
| 2024 | 4 |
| 2025 | 3 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 25
- Phase 2
- 80
- Phase 3
- 94
- Phase 4
- 70
- No phase
- 22
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 88 · Other 184
Novartis Pharmaceuticals (58) · Novartis (19) · Massachusetts General Hospital (5) · Alliance for Clinical Trials in Oncology (4) · University of Wisconsin, Madison (4) · University of Nebraska (3) · Ottawa Hospital Research Institute (3) · M.D. Anderson Cancer Center (3)
Often tested with
Tested in the same studies.
Denosumab (11) · Letrozole (8) · Docetaxel (6) · Alendronate (4) · Teriparatide (3) · Interleukin-2 (3) · Cyclophosphamide (3) · Romosozumab (3)
Studies
Open first, then newest update. How each study uses Zoledronic Acid is read from its arms, and is right about nine times in ten.
Testing it · 272
- Bisphosphonate Prior to Parathyroidectomy in Primary HyperparathyroidismRecruitingPhase 4University of AarhusNCT06859580Written as Zoledronic acid 4 mg
- Zoledronate to Prevent Bone Health Complications in Pediatric Hematopoietic Stem Cell Transplant SurvivorsRecruitingPhase 1Children's Hospital Medical Center, CincinnatiNCT07375290Written as Zoledronate
- The Optimised Use of Romozosumab StudyRecruitingPhase 4University of AarhusNCT06059222Written as Zoledronate
- Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid TumorsRecruitingPhase 1/2University of FloridaNCT06625190Written as Zoledronic acid
- EFFICACY AND SAFETY OF ZOLEDRONATE VERSUS PLACEBO ON PAIN AT WEEK 12 IN PEDIATRIC PATIENTS WITH CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITISNot yet recruitingPhase 2Assistance Publique - Hôpitaux de ParisNCT07668583Written as Zoledronic Acid / Zoledronate 4 MG/100 ML Intravenous Solution
- Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic AmenorrheaRecruitingPhase 3Massachusetts General HospitalNCT06533865Written as Zoledronic acid
- Local Bisphosphonate Effect on Recurrence Rate in Extremity Giant Cell Tumor of BoneRecruitingPhase 3St. Louis UniversityNCT03295981Written as Zoledronic Acid
- Zoledronic Acid Treatment in Patients With Congenital Dyserythropoietic AnemiaRecruitingPhase 1/2Institute of Hematology & Blood Diseases Hospital, ChinaNCT07471516Written as zoledronic acid
- Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill AdultsRecruitingPhase 2Australian and New Zealand Intensive Care Research CentreNCT04608630Written as Zoledronic Acid 5Mg/Bag 100Ml Inj
- Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid TumorsRecruitingPhase 1University of Wisconsin, MadisonNCT02508038Written as Zoledronate
- Zoledronic Acid for the Prevention of TDF-sparing ART-induced Bone Mass Density Loss in Treatment-naive HIV Positive IndividualsRecruitingPhase 4Hadassah Medical OrganizationNCT06762730Written as Zoledronic Acid 5 mg/Bag 100 ml Inj
- The Effect of Zoledronate on the Prevention of Pneumonia in Hip Fracture PatientsRecruitingPhase 4The University of Hong KongNCT05743179Written as Zoledronate
- A Study to Assess the Prevention of Bone-related Events in Patients With Bone Metastases From Malignant Solid Tumors Treated With JMT103 Compared to Zoledronic AcidNot yet recruitingPhase 3Shanghai JMT-Bio Inc.NCT06221072Written as zoledronic acid
- Effect of Zoledronic Acid in Primary Knee OsteoarthritisRecruitingPhase 4Toufiqe-E-EalahiNCT06051344Written as Zoledronic acid
- Efficacy of a Herbal Formula for Bone MetastasesNot yet recruitingPhase 1/2Chinese University of Hong KongNCT06023420Written as 4 Herbs Formula
- HAIC Combined Withzoledronic Acid for the Prevention of Bone Metastases in Advanced HCCRecruitingPhase 3Sun Yat-sen UniversityNCT05866172Written as Zoledronic acid
- Zoledronic Acid in Combination With Interleukin-2 to Expand Vγ9Vδ2 T Cells After T-replete Haplo-identical AllotransplantCompletedPhase 1Nantes University HospitalNCT03862833Written as Zoledronic Acid
- Comparing a Single-Dose vs. Twice Yearly Zoledronate in Patients With Early Stage Breast Cancer (REaCT-ZOL)CompletedPhase 4Ottawa Hospital Research InstituteNCT03664687Written as Zoledronate
- Trial of Parkinson's And Zoledronic AcidCompletedPhase 4California Pacific Medical Center Research InstituteNCT03924414Written as Zoledronic Acid 5Mg/Bag 100Ml Inj
- Treatment of Osteogenesis Imperfecta With Parathyroid Hormone and Zoledronic AcidCompletedPhase 4University of EdinburghNCT03735537Written as Zoledronic Acid
See all 272 studies that test Zoledronic Acid →
Given in every arm · 20 — Zoledronic Acid is usual care beside what is tested
- Step-down Therapy After Long-term Osteoporosis TreatmentRecruitingPhase 4National Taiwan University HospitalNCT07281586Written as zoledronate
- ETC-159 In Combination With Pembrolizumab In Advanced MSS/pMMR Ovarian CancersRecruitingPhase 1National University Hospital, SingaporeNCT06513624Written as Denosumab / Zoledronic Acid
- Continuous Passive Motion Versus Heterotopic OssificationRecruitingNot applicableUniversity of IoanninaNCT05906056Written as Zoledronic Acid Injection
- The Role of Bisphosphonate and Simvastatin Combination on Therapeutic Response in Breast Cancer With Bone Metastasis Via Dicckopf-1 PathwayCompletedNot applicableUniversitas IndonesiaNCT07823751Written as Zoledronic Acid (Zometa)
- Zoledronate Early to Hip Fracture Patients - Safe and Effective?CompletedPhase 4Lene Bergendal SolbergNCT05025293Written as Zoledronic Acid 5Mg/Bag 100Ml Inj
- Ixazomib Citrate, Lenalidomide, Dexamethasone, and Zoledronic Acid or Zoledronic Acid Alone After Radiation Therapy in Treating Patients With Solitary Plasmacytoma of BoneTerminatedPhase 3Alliance for Clinical Trials in OncologyNCT02516423Written as zoledronic acid
- Romosozumab Use to Build Skeletal IntegrityActive, not recruitingPhase 4Susan L. GreenspanNCT05058976Written as Zoledronic acid
- FARE Augmentation of Proximal Femoral Fractures With CaS/HA and Systemic ZACompletedPhase 4Aksaray UniversityNCT06135298Written as Zoledronic acid
- Effects of Romosozumab on Bone Density in Women With Anorexia NervosaCompletedPhase 3Karen Klahr Miller, MDNCT04779216Written as Zoledronic acid 5 mg
- Denosumab to Prevent High-Turnover Bone Loss After Bariatric SurgeryCompletedPhase 4Massachusetts General HospitalNCT04087096Written as Zoledronic Acid
- Zoledronate, Vitamin D, and Calcium With or Without Strontium 89 or Samarium 153 in Preventing or Delaying Bone Problems in Patients With Bone Metastases From Prostate Cancer, Lung Cancer, or Breast CancerCompletedPhase 3Radiation Therapy Oncology GroupNCT00365105Written as zoledronic acid
- Trochanteric Femur Fracture Operated With Dynamic Hip Screw System (DHS) Augmented With a Biphasic Apatite Sulphate Combined With Systemic or Local BisphosphonateActive, not recruitingNot applicableLithuanian University of Health SciencesNCT04498715Written as Zoledronic Acid
- A Study in Adult Patients With Type I, III or IV Osteogenesis Imperfecta Treated With BPS804CompletedPhase 2Ultragenyx Pharmaceutical IncNCT03118570Written as zoledronic acid (optional)
- Denosumab and Teriparatide Study (DATA-HD and DATA-EX)CompletedPhase 4Massachusetts General HospitalNCT02176382Written as Zoledronic acid
- Pharmacokinetic, Safety and Tolerability Study of SC Administered Bisphosphonate With rHuPH20 vs Bisphosphonate AloneCompletedPhase 1Halozyme TherapeuticsNCT00807963Written as zoledronic acid
- Hormone Ablation Therapy, Doxorubicin, and Zoledronate With or Without Strontium 89 in Treating Patients With Androgen-Dependent Prostate Cancer and Bone MetastasesCompletedPhase 2M.D. Anderson Cancer CenterNCT00081159Written as Zoledronic acid
- Combination Bisphosphonate and Anti-Angiogenesis Therapy With Pamidronate and ThalidomideCompletedPhase 2University of ArkansasNCT00083382Written as Zometa
- Phase III Randomized Trial of Thalidomide/Dexamethasone Versus Vincristine+Adriamycin+Dexamethasone (VAD)TerminatedPhase 3H. Lee Moffitt Cancer Center and Research InstituteNCT00215943Written as zoledronic acid
- Zoledronate and BMS-275291 in Treating Patients With Prostate CancerCompletedPhase 2National Cancer Institute (NCI)NCT00039104Written as zoledronic acid
- Zoledronate With or Without Thalidomide in Treating Patients With Early Stage Multiple MyelomaCompletedPhase 3Mayo ClinicNCT00432458Written as zoledronic acid
As the comparator · 22 — what is tested is compared with Zoledronic Acid
- Zunsemetinib in Combination With Capecitabine in Patients With Hormone Receptor-Positive and HER2-Negative Metastatic Breast Cancer With Bone MetastasisRecruitingPhase 1/2Washington University School of MedicineNCT06374459Written as Zoledronic acid
- Preserving Geriatric Muscle With an Osteoporosis MedicationRecruitingPhase 4Chrissy KistlerNCT06118905Written as Zoledronic Acid 5Mg/Bag 100Ml Infusion
- The Comparison of Ibandronate and Zoledronic Acid After Denosumab DiscontinuationRecruitingPhase 4National Taiwan University HospitalNCT07406685Written as Zoledronic acid IV
- Sequential Treatment With Romosozumab Followed by Denosumab vs. Zoledronic Acid for Gains in HIP BMDNot yet recruitingPhase 4Sahlgrenska University HospitalNCT07772609Written as Zoledronic Acid 5 MG in 5 ML Injection
- Denosumab vs Zoledronate After Lumbar FusionStatus unknownPhase 3Shenzhen People's HospitalNCT05638399Written as Zoledronate
- Denosumab vs Zoledronate After VertebroplastyCompletedPhase 4Shenzhen People's HospitalNCT05598606Written as Zoledronate
- Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple MyelomaCompletedPhase 3AmgenNCT01345019Written as Zoledronic acid
- A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects.CompletedPhase 3AmgenNCT00321464Written as Zoledronic Acid
- Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma.CompletedPhase 3AmgenNCT00330759Written as Zoledronic Acid
- Evaluation of Romosozumab vs. Zoledronic Acid Effect in Patients With Spinal Cord Injury and Low Bone Mineral DensityStatus unknownPhase 4Sheba Medical CenterNCT04597931Written as Zoledronic Acid
- A Study of AL2846 Versus Zoledronic Acid in Subjects With Advanced Non-Small Cell Lung Cancer With Bone MetastasisStatus unknownPhase 2Chia Tai Tianqing Pharmaceutical Group Co., Ltd.NCT04325776Written as Zoledronic Acid Injection
- Denosumab for the Treatment of Osteoporosis in Children: A Pilot StudyCompletedPhase 2Children's Hospital of Eastern OntarioNCT02632916Written as Zoledronic Acid
- Safety and Efficacy Study to Evaluate Denosumab Compared With Zoledronic Acid in Postmenopausal Women With OsteoporosisCompletedPhase 4AmgenNCT01732770Written as Zoledronic Acid
- Treating Idiopathic Inflammatory Myopathies Related Reduced Bone Mineral Density With Denosumab or Zoledronic AcidStatus unknownPhase 3Kwong Wah HospitalNCT04034199Written as Zoledronic Acid
- Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Men With Hormone-refractory Prostate CancerCompletedPhase 3AmgenNCT00321620Written as zoledronic acid
- A Study to Examine the Effects of an Experimental Drug on Women With Breast Cancer and Metastatic Bone Disease (MBD)(0822-016)(COMPLETED)CompletedPhase 2Merck Sharp & Dohme LLCNCT00399802Written as ZA
- A Study to Assess the Efficacy of Intravenous Bondronat (Ibandronate) in Patients With Malignant and Painful Bone DiseaseTerminatedPhase 3Hoffmann-La RocheNCT00099203Written as zoledronic acid
- A Study to Assess the Efficacy of Intravenous/Oral Bondronat (Ibandronate) in Patients With Metastatic Bone Disease Experiencing Moderate to Severe PainTerminatedPhase 3Hoffmann-La RocheNCT00099177Written as zoledronic acid
- Comparison of Ibandronate - Zoledronate Regarding Nephrotoxicity in Multiple MyelomaTerminatedPhase 3Hoffmann-La RocheNCT02739594Written as Zoledronate
- Open Label Dose Escalation Phase I Study to Investigate the Safety and Pharmacokinetics of T121E01F and T121E02F in Healthy Postmenopausal WomenCompletedPhase 1Thar Pharmaceuticals, IncNCT01721993Written as Zoledronic acid
Showing 20 of 22.
Codes
What other systems call Zoledronic Acid · ClinicalTrials.gg INT006666
- MeSH (NLM) D000077211Zoledronic AcidConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 6XC1PAD3KFZOLEDRONIC ACIDConfirmed FDA, NLM, Wikidata
- RxNorm 77655Confirmed FDA, Wikidata
- Wikidata Q28852343zoledronic acid monohydrateConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C1699Zoledronic AcidConfirmed FDA, Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000077211 | Zoledronic Acid | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 6XC1PAD3KF | ZOLEDRONIC ACID | Confirmed FDA, NLM, Wikidata |
| RxNorm | 77655 | — | Confirmed FDA, Wikidata |
| Wikidata | Q28852343 | zoledronic acid monohydrate | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C1699 | Zoledronic Acid | Confirmed FDA, Wikidata |
Also registered as zoledronic acid anhydrous (UNII 70HZ18PH24 · RxNorm 1546014).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.