Multiple Sclerosis, Relapsing-Remitting clinical trials
The registry lists 618 studies for Multiple Sclerosis, Relapsing-Remitting across more than 10 countries. 82 are recruiting or about to start. 551 of them are mainly about Multiple Sclerosis, Relapsing-Remitting (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
ClinicalTrials.gov finds 745 studies for Multiple Sclerosis, Relapsing-Remitting. How that becomes 616 here
This page counts the studies the registry files under Multiple Sclerosis, Relapsing-Remitting, and those it files under no condition that list Multiple Sclerosis, Relapsing-Remittingthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 745Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −1List Multiple Sclerosis, Relapsing-Remitting as a condition, but the registry did not file them under itMost often written as “Relapsing Remitting Multiple Sclerosis RRMS” (1). The registry filed them under other conditions only, most often Multiple Sclerosis (1).
- −128Match it another way90 name it in the title, 2 in a keyword, and 36 by a synonym or other text the search reads.
- 616The count on this page1 of them list Multiple Sclerosis, Relapsing-Remitting in their own words; the registry filed them under no condition.
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· Enrollment: 300 → 450 participants
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Who runs them
Biogen (78) · Novartis Pharmaceuticals (30) · Merck KGaA, Darmstadt, Germany (26) · Bayer (17) · Teva Branded Pharmaceutical Products R&D, Inc. (12) · Hoffmann-La Roche (11) · GlaxoSmithKline (9) · Johns Hopkins University (9)
What is being tested here
Drugs under test in Multiple Sclerosis, Relapsing-Remitting studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ublituximab | 3 | 0 | 4 |
| Ocrelizumab | 2 | 6 | 10 |
| Rituximab | 2 | 5 | 7 |
| Cladribine | 1 | 2 | 5 |
| Clemastine | 1 | 0 | 2 |
| Remibrutinib | 1 | 0 | 1 |
| Taurine | 1 | 0 | 1 |
| Ifenprodil | 1 | 0 | 1 |
| Ozanimod | 1 | 1 | 1 |
| Rocbrutinib | 1 | 0 | 1 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 2 open · Antihistamines 2 open · Antimetabolites 1 open · Corticosteroids 5 · Statins 5
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Nov 2026Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis · Phase 3 · Immunic AG
- Jan 2027Disease Modifying Therapies Withdrawal in Inactive Relapsing-remitting Multiple Sclerosis Patients Aged 55 and Over (TWINS : Therapies Withdrawal IN Relapsing Multiple Sclerosis) · Phase 3 · University Hospital, Strasbourg, France
- Feb 2027A Study to Compare Efficacy, Pharmacokinetics, Pharmacodynamics and Safety of CT-P53 and Ocrevus in Patients With Relapsing-remitting Multiple Sclerosis · Phase 3 · Celltrion
- Apr 2027Comparison Between ABP 692 and Ocrevus® (Ocrelizumab) · Phase 3 · Amgen
- May 2027Non-inferiority Study of Rituximab Compared to Ocrelizumab in Relapsing MS · Phase 3 · Amsterdam UMC, location VUmc
- May 2027A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis · Phase 3 · Biogen
- Nov 2026MultiSCRIPT-Cycle 1: Personalized Medicine in Multiple Sclerosis - Pragmatic Platform Trial Embedded Within the SMSC · University Hospital, Basel, Switzerland
- Nov 2026Functional Outcomes From Diets in Multiple Sclerosis · University of Alabama at Birmingham
- Nov 2026Home Based Functional Balance Intervention for Multiple Sclerosis · University of Illinois at Chicago
- Dec 2026Peer Support Impact on Therapeutic Adherence in Patients With Multiple Sclerosis · Nantes University Hospital
Who these studies take
Of the 59 Multiple Sclerosis, Relapsing-Remitting studies recruiting now, 11 (19%) set no upper age limit and 42 (71%) stop at 75 or younger. 2 (3%) take children under 18. 1 (2%) are for women only and 1 (2%) for men only; 11 (19%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (2%) | 1 (2%) |
| 18 | 49 (83%) | 50 (85%) |
| 30 | 53 (90%) | 53 (90%) |
| 40 | 56 (95%) | 56 (95%) |
| 50 | 56 (95%) | 56 (95%) |
| 65 | 34 (58%) | 34 (58%) |
| 75 | 21 (36%) | 21 (36%) |
| 85 | 15 (25%) | 15 (25%) |
Across all 618 studies, recruiting or not: 75% stop at 75 or younger and 70% at 65; 6% take children; 2% are for women only and 1% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Multiple Sclerosis, Relapsing-Remitting studies take
Of 38 phase 3 interventional studies under Multiple Sclerosis, Relapsing-Remitting, half reached primary completion within 48 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 8 mo3–41 · 16 studies | — | — |
| Phase 2 | 41 mo22–67 · 25 studies | — | — |
| Phase 3 | 48 mo27–66 · 38 studies | 38 mo26–65 · 28 studies | — |
| Phase 4 | 48 mo22–66 · 28 studies | — | — |
| Interventional, no phase | 29 mo15–47 · 81 studies | — | 29 mo15–45 · 79 studies |
| Observational | 41 mo23–55 · 67 studies | 28 mo20–55 · 26 studies | 48 mo34–56 · 41 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 12, 2026.
Newly registered5
- THE EFFECTS OF TAI CHI IN INDIVIDUALS WITH MULTIPLE SCLEROSISNov 10, 2026NCT07928557
- Psychodrama for Adults With Relapsing-Remitting Multiple Sclerosis: A Mixed-Methods StudyNov 10, 2026NCT07928765
- Non-invasive Brain Stimulation to Improve Memory in Multiple SclerosisNov 3, 2026NCT07914257
- REAL-MS: Observational Database Study of AHSCT and MS TherapiesOct 27, 2026NCT07899502
- Tai Chi Training for Persons With Multiple Sclerosis.Oct 23, 2026NCT07890974
Studies
Recruiting first, then most recently updated. Showing 50 of 618. Browse all 618 → or search them.
- Non-invasive Brain Stimulation to Improve Memory in Multiple SclerosisNot yet recruitingNCT07914257Not applicable1 country
- Monthly Monitoring of Plasma NfL in Treated Relapsing-remitting Multiple Sclerosis to Detect Persistent Infraclinical Disease ActivityRecruitingNCT07292480Not applicable1 country
- Wearable Focal Vibration Therapy on Upper Extremity Function of People With Multiple Sclerosis: A Pilot StudyRecruitingNCT07376772Not applicable1 country
- Non-interventional Study of Subcutaneous Ocrelizumab in Persons With Relapsing-Remitting Multiple SclerosisRecruitingNCT078275862 countries
- REAL-MS: Observational Database Study of AHSCT and MS TherapiesRecruitingNCT078995021 country
- The HIt HArd and hiT Early in Multiple Sclerosis TrialRecruitingNCT07517185Phase 21 country
- Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS)RecruitingNCT04047628Phase 31 country
- A Study to Evaluate Pharmacokinetics, Safety, Tolerability, Immunogenicity and Pharmacodynamic Effects of Subcutaneous Ocrelizumab Administration in Children and Adolescents With Relapsing-remitting Multiple Sclerosis (RRMS)Not yet recruitingNCT07503340Phase 2
- Identifying Immune Biomarkers of Disease and Disease Control in Autoimmune Neurological Disease Using Autologous Haematopoietic Stem Cell TransplantationRecruitingNCT061958001 country
- Fatigue Alleviation Through Neuromodulating Therapy in Multiple SclerosisRecruitingNCT06569550Not applicable1 country
- Clinnova-MS: A Prospective Cohort Study of Patients With Multiple Sclerosis: A Trans-regional Digital Health Effort Unlocking the Potential of Artificial Intelligence and Data Science in Health CareNot yet recruitingNCT072808711 country
- A Study to Evaluate the Preliminary Efficacy and Safety of Terfenadine in Patients With Relapsing-Remitting Multiple SclerosisRecruitingNCT07827716Phase 21 country
- Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current StimulationRecruitingNCT05958381Not applicable1 country
- Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple SclerosisRecruitingNCT06408259Phase 311 countries
- SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple SclerosisRecruitingNCT03783416Phase 11 country
- The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot StudyRecruitingNCT06796504Not applicable1 country
- A Study of Rocbrutinib in PRL-Positive Relapsing-Remitting Multiple SclerosisRecruitingNCT07776743Phase 21 country
- A Study of Remibrutinib Using MR Imaging in Relapsing or Progressive MSNot yet recruitingNCT07222956Phase 21 country
- Brain Imaging and Immune Changes During Remibrutinib Treatment in Multiple Sclerosis.RecruitingNCT077582701 country
- Sociocognitive Intervention and Rehabilitation Program in Multiple SclerosisNot yet recruitingNCT07734675Not applicable1 country
- Exploration of Novel Imaging Biomarkers on OCT for Ublituximab Treatment Response in Multiple SclerosisRecruitingNCT06864936Not applicable1 country
- Effects of Powered Hip Flexion Device in Persons With Multiple SclerosisNot yet recruitingNCT07724093Not applicable1 country
- Study to Investigate Vagus Nerve Stimulation Paired With Motor Task for Remyelination and Functional RecoveryEnrolling by invitationNCT06641271Not applicable1 country
- Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair TherapyRecruitingNCT05359653Phase 1/21 country
- A Prospective Randomized Non-inferiority Trial Comparing Anti-CD20 Maintenance Versus De-Escalation Strategy In Relapsing-Remitting Multiple SclerosisRecruitingNCT07189325Phase 31 country
- Motor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple SclerosisRecruitingNCT06919900Not applicable1 country
- PRIMUS : Real World Usage for Real World Evidence of CDSS Use in Multiple SclerosisNot yet recruitingNCT07647952Not applicable1 country
- Effects of Low-Load Blood Flow Restriction Exercise on Rectus Femoris Muscle Morphology in Individuals With Relapsing-Remitting Multiple SclerosisNot yet recruitingNCT07645937Not applicable
- Acute Intermittent Hypoxia Combined With Gait Training in Multiple SclerosisNot yet recruitingNCT07631923Not applicable
- Healthy Eating and Active Living for People Living With Multiple Sclerosis (HEAL MS): A Lifestyle Program for People With Multiple SclerosisNot yet recruitingNCT07589062Not applicable1 country
- ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMSRecruitingNCT06733922Phase 41 country
- Combined Motor Imagery and Vestibular Rehab for MSRecruitingNCT07230015Not applicable1 country
- Multicenter Prospective Study Analyzing the Occurrence of Multiple Sclerosis Relapses Without Radiological Evidence: Myth or Reality?Not yet recruitingNCT07545889Not applicable1 country
- Effects of Ocrelizumab Treatment on Immune Cells in Lymph Nodes in Multiple SclerosisEnrolling by invitationNCT06495593Phase 41 country
- Intermittent Hypoxia in Persons With Multiple SclerosisRecruitingNCT06276634Not applicable1 country
- Ublituximab (Briumvi) for Early Forms of Relapsing Multiple SclerosisRecruitingNCT07225361Phase 41 country
- Cognitive Performance, Sleep Disturbances and Fatigue in Multiple SclerosisRecruitingNCT074269911 country
- Effects of Acute Intermittent Hypoxia on Neuroplasticity in MSRecruitingNCT06390930Not applicable1 country
- Effects of Ublituximab on Motor Functions in Multiple SclerosisRecruitingNCT06629428Early Phase 11 country
- RItuximab Versus Ocrelizumab in Relapsing-remitting Multiple Sclerosis.RecruitingNCT05758831Phase 31 country
- Indole-3-PROpionic Acid Clinical Trials - Multiple SclerosisRecruitingNCT07318129Not applicable1 country
- Home Based Functional Balance Intervention for Multiple SclerosisRecruitingNCT07355387Not applicable1 country
- A Study of the Efficacy and Safety of BCD-281 in Patients With Relapsing-Remitting Multiple SclerosisRecruitingNCT07321093Phase 31 country
- Clinnova-MS: A Prospective Cohort Study of Patients With Multiple Sclerosis (Switzerland)RecruitingNCT065263641 country
- Behavioral Intervention for Physical Activity and Sexual Dysfunction in Multiple SclerosisNot yet recruitingNCT04768777Not applicable1 country
- A Multicenter Clinical Trial Evaluating the Efficacy and Safety of Taurine as an Adjunctive Therapy in Multiple SclerosisNot yet recruitingNCT07263607Phase 2
- "Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MSRecruitingNCT072226181 country
- Sexual Dysfunction in Women With Multiple Sclerosis (MS)RecruitingNCT071938231 country
- Impact of the Cionic Neural Sleeve on Mobility in Multiple SclerosisRecruitingNCT05964829Not applicable1 country
- Understanding the 'Durable Effect' Concept of B-cell Modulating TherapiesRecruitingNCT065861771 country