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Autoimmune Diseases of the Nervous System clinical trials

The registry lists 123 studies for Autoimmune Diseases of the Nervous System across more than 10 countries. 59 are recruiting or about to start. 61 of them are mainly about Autoimmune Diseases of the Nervous System (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27. Counting its 14 narrower conditions too, such as Multiple Sclerosis: 4,551 studies, 1,031 open.

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Status

Recruiting
44
Completed
39
Not yet recruiting
14
Active, not recruiting
9
Status unknown
6
Terminated
5

Phase

Phase 2
22
Phase 1
12
Phase 3
7
Early Phase 1
3
Phase 4
3

Where

France
35
United States
28
China
26
United Kingdom
10
Italy
8
Spain
6

Who runs them

Hospices Civils de Lyon (22) · Tongji Hospital (7) · Xuanwu Hospital, Beijing (5) · University Hospital, Bordeaux (3) · Shen Chun-Hong (3) · Fondazione Policlinico Universitario Agostino Gemelli IRCCS (2) · King's College London (2) · Beijing Tiantan Hospital (2)

Who develops what

Save this set

Every programme with a company-led study here in the last two years, whatever its size: 5 programmes from 5 companies, 2 with this as their studies’ main aim; 0 with a live phase 3 study; 0 primary completions in the next 12 months.

Comparator & background therapies

What other companies’ phase 2+ studies give as the comparator or the background here (its leading trial sponsor and partners left out): a sign of what new drugs are measured against, not by itself the standard of care, its prescriptions or its market.

DrugLeading trial sponsor · rightsCompanies, last 5 years
Methylprednisolone HemisuccinateRecent, limited
Evidence
  • NCT05177939 · Nihon Pharmaceutical Co., Ltd · Phase 3 · comparator · “NPB-01-ME” · registered Dec 2021
—11 study

Programmes

“Meets, by arms” reads each study’s arms: vs its arm against the therapy’s; + X vs a combination against it; added to it plus the therapy against the therapy; studied with given together only. The next primary completion is the next phase-3 study’s when there is one.

The 5 programmes — sign in to see the whole list, free: filter by phase and aim, sort by late development, direct comparisons or the next primary completion.

Primary completion in the next 12 months (0)

Live phase 2 and 3 studies of these programmes. Primary completion is when the main measure’s data collection ends, as the registry states it (most are estimates); results come later, if they are announced.

None in the next 12 months.

Read from ClinicalTrials.gov, industry-led studies. Main aim: this is the study’s judged main condition; named, not the main aim: the sponsor names it, the study is about something else; registry mapping only: only the registry’s mapping put it here. Leading trial sponsor is the company leading the most industry studies of a drug, a measure of trial activity, not of rights. US and EU rights, and Approved: from the regulators’ records (FDA’s Drugs@FDA via openFDA; EMA’s medicines data) — the holder of a marketed or authorised original, generics and other companies’ versions; not rights elsewhere, nor approval for this condition. Phase 4 trial recorded, where neither lists it: a phase 4 study exists somewhere. Not read yet: labels by indication, exclusivity, licences, line of therapy, academic comparators, sales.

What is being tested here

Drugs under test in Autoimmune Diseases of the Nervous System studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Efgartigimod alfa202
ART5803103
Rituximab112
Allogeneic CRISPR-Cas9 Engineered Anti-CD19 CAR T-cells CTX112101
Blinatumomab101
Anitocabtagene autoleucel101
Ofatumumab111
Daratumumab111
Allogeneic Anti-CD19 CAR-gamma/delta T-cells QH103101
Natalizumab101

Coming up

4phase 3 studies under way
21studies finish main data collection within a year3 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 44 Autoimmune Diseases of the Nervous System studies recruiting now, 27 (61%) set no upper age limit and 11 (25%) stop at 75 or younger. 15 (34%) take children under 18. 1 (2%) are for women only and 0 (0%) for men only; 9 (20%) take healthy volunteers.

Recruiting studies that take each age, of 44
AgeWomenMen
1011 (25%)11 (25%)
1842 (95%)42 (95%)
3041 (93%)40 (91%)
4040 (91%)39 (89%)
5040 (91%)39 (89%)
6538 (86%)38 (86%)
7536 (82%)36 (82%)
8531 (70%)31 (70%)

Across all 123 studies, recruiting or not: 33% stop at 75 or younger and 23% at 65; 33% take children; 1% are for women only and 0% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Autoimmune Diseases of the Nervous System studies take

Of 28 observational studies under Autoimmune Diseases of the Nervous System, half reached primary completion within 53 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Observational53 mo17–… · 28 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 16, 2026.

Started recruiting1

Studies

Recruiting first, then most recently updated. Showing 50 of 123. Browse all 123 → or search them.