Drug
4-Aminopyridine clinical trials
Also written Ampyra, Dalfampridine, Fampyra and BIIB041.
- studies test it
- 61
- open now
- 12
- in phase 3
- 20
- first study started
- 2002
Keep track of what changes. Save the 4-Aminopyridine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
59 studies that test it; most in 2014 (8); 1 more planned to start later
| Year | Studies |
|---|---|
| 2002 | 3 |
| 2003 | 2 |
| 2005 | 1 |
| 2006 | 1 |
| 2007 | 2 |
| 2010 | 3 |
| 2011 | 2 |
| 2012 | 6 |
| 2013 | 4 |
| 2014 | 8 |
| 2015 | 2 |
| 2016 | 2 |
| 2018 | 2 |
| 2019 | 2 |
| 2020 | 1 |
| 2021 | 4 |
| 2022 | 3 |
| 2024 | 1 |
| 2025 | 5 |
| 2026 | 5 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 5
- Phase 2
- 25
- Phase 3
- 20
- Phase 4
- 9
- No phase
- 6
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 16 · Other 45
Acorda Therapeutics (10) · Biogen (6) · John Elfar (4) · Prof. Dominique de Quervain, MD (3) · University of Southern Denmark (3) · Shirley Ryan AbilityLab (2) · Coordinación de Investigación en Salud, Mexico (2) · Milton S. Hershey Medical Center (2)
Often tested with
Tested in the same studies.
Imatinib (1) · Oral Tablet Dosage Form (1) · Extended Release Dosage Form (1) · Atenolol (1)
Studies
Open first, then newest update. How each study uses 4-Aminopyridine is read from its arms, and is right about nine times in ten.
Testing it · 61
- Cross-over Study on the Influence of Fampridine on Working Memory in Mild to Moderate DepressionRecruitingPhase 2University of BaselNCT06751784Written as Fampridine SR
- Single Dose 4-Aminopyridine for Diagnosing Recurrent Laryngeal Nerve Paralysis Continuity After TraumaNot yet recruitingPhase 1Milton S. Hershey Medical CenterNCT07832331Written as 4-Aminopyridine
- The Role of Potassium Channels in Working Memory Impairments of Chronic Cocaine UsersRecruitingNot applicableBoris QuednowNCT07532460Written as 4-aminopyridine (4-AP)
- Dalfampridine Combined With Physical Therapy for Mobility Impairment in Multiple SclerosisRecruitingPhase 3MGH Institute of Health ProfessionsNCT06136728Written as Dalfampridine 10 MG [Ampyra]
- Double Dose 4-AP on Functional Recovery After Spinal Cord InjuryRecruitingPhase 1/2Shirley Ryan AbilityLabNCT06853015Written as Dalfampridine
- Preoperative Imatinib and Fampridine in KIT Mutant Gastrointestinal Stromal TumorRecruitingPhase 1University of California, San DiegoNCT07171203Written as Fampridine
- 4-Aminopyridine to Treat Skin BurnsRecruitingPhase 2John ElfarNCT06596434Written as Drug: 4-Aminopyridine
- 4AP for Carpal Tunnel Syndrome (CTS)Not yet recruitingPhase 2John ElfarNCT06294821Written as 4-Aminopyridine
- 4-aminopyridine Treatment for Nerve InjuryRecruitingPhase 2/3John ElfarNCT03701581Written as 4-Aminopyridine
- A Randomized, Parallel-arm, Double Blind, Placebo-controlled Study to Assess the Efficacy of Fampridine for Patients With Spinocerebellar Ataxia SCA27B Caused by a GAA Expansion in the FGF14 GeneRecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT07185347Written as Fampridine 10 mg prolonged-release tablet (per os)
- 4-aminopyridine for Skin Wound HealingRecruitingPhase 2John ElfarNCT06333171Written as 4-Aminopyridine
- 4-AP Peripheral Nerve Crossover TrialRecruitingPhase 2University of ArizonaNCT06003166Written as 4-Aminopyridine
- Use of Dalfampridine in Primary Lateral SclerosisCompletedPhase 1Hospital for Special Surgery, New YorkNCT02868567Written as dalfampridine
- Effects of 4-AP on Functional SCI RecoveryCompletedEarly Phase 1Shirley Ryan AbilityLabNCT05447676Written as Dalfampridine
- Influence of Fampridine on Working Memory in Healthy SubjectsWithdrawnPhase 2Prof. Dominique de Quervain, MDNCT04516603Written as Fampridine SR
- Short and Long Term Treatment With 4-AP in Ambulatory SMA PatientsCompletedPhase 2/3Columbia UniversityNCT01645787Written as 4-aminopyridine
- Influence of Fampridine on Working Memory in Individuals With Post COVID-19 Condition With Subjective Cognitive ImpairmentTerminatedNot applicableProf. Dominique de Quervain, MDNCT05274477Written as Fampridine SR
- 4-Aminopyridine, Atenolol, or Placebo in Patients With Vestibular MigraineWithdrawnPhase 2Massachusetts Eye and Ear InfirmaryNCT03578354Written as 4-aminopyridine
- Dalfampridine in Egyptian Patients With Multiple SclerosisStatus unknownNot applicableAin Shams UniversityNCT05730738Written as Dalfampridine ER, 10 Mg Oral Tablet, Extended Release
- Influence of Fampridine on Working Memory in Healthy Young SubjectsCompletedPhase 2Prof. Dominique de Quervain, MDNCT04652557Written as Fampridine SR
Codes
What other systems call 4-Aminopyridine · ClinicalTrials.gg INT008495
- MeSH (NLM) D0157614-AminopyridineConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) BH3B64OKL9DALFAMPRIDINEConfirmed FDA, NLM
- RxNorm 897018One source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D015761 | 4-Aminopyridine | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | BH3B64OKL9 | DALFAMPRIDINE | Confirmed FDA, NLM |
| RxNorm | 897018 | — | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.