Lipid Metabolism Disorders clinical trials
The registry lists 177 studies for Lipid Metabolism Disorders across more than 10 countries. 36 are recruiting or about to start. 41 of them are mainly about Lipid Metabolism Disorders (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13. Counting its 32 narrower conditions too, such as Dyslipidemias: 4,362 studies, 604 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Status
Who runs them
Pfizer (6) · University of Texas Southwestern Medical Center (5) · Kastle Therapeutics, LLC (5) · Akcea Therapeutics (4) · University of Colorado, Denver (3) · University of Palermo (2) · National Heart, Lung, and Blood Institute (NHLBI) (2) · Maastricht University Medical Center (2)
What is being tested here
Drugs under test in Lipid Metabolism Disorders studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Ezetimibe | 1 | 0 | 3 |
| Metformin | 1 | 0 | 2 |
| Liraglutide | 1 | 0 | 2 |
| Bempedoic acid | 1 | 0 | 1 |
| Aripiprazole | 1 | 0 | 1 |
| Paliperidone | 1 | 0 | 1 |
| Zodasiran | 1 | 1 | 1 |
| Eicosapentaenoic Acid | 1 | 0 | 1 |
| Docosahexaenoic Acids | 1 | 0 | 1 |
| Semaglutide | 1 | 0 | 1 |
Drug classes tested here Statins 1 open · PCSK9 inhibitors 1 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026Comorbidities Resolution After MGB Surgery and Change in Body Composition · All India Institute of Medical Sciences, Bhubaneswar
- Dec 2026Heart CT Imaging to Detect Early Coronary Artery Disease in First-Degree Relatives With High or Low Lipoprotein(a) Identified Through Family Screening · E.S.stroes
- Jan 2027Screening for Disorders of Lipid Metabolism and Familial Hyperlipidemia in Children and Adolescents With Increased Cardiovascular Risk Due to Chronic Diseases Such as Congenital Heart Disease, Chronic Inflammatory Bowel Disease, Celiac Disease and Rheumatic Disorders · Alexandra Miriam Kiess
- Feb 2027Metabolic Effects of an Ophiocordyceps Sinensis- and CoQ10-Based Formulation in Mild-to-Moderate Hypercholesterolemia · noiVita Srls
- Mar 2027Cardiovascular-Renal Adverse Prognosis Assessment System for Coronary Heart Disease With Chronic Kidney Disease Based on Metabolomics · China-Japan Friendship Hospital
- Apr 2027Multicomponent Intervention Study- Blood Donors With High Cholesterol · University of Texas Southwestern Medical Center
- Jun 2027A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias · CRISPR Therapeutics AG
- Jun 2027Metabolism and Sleep Apnea Treatment · University of Miami
- Jul 2027Late Subclinical Cardiovascular Disease in Testicular Cancer Survivors · Indiana University
- Aug 2027Differential Thrombogenesis by EPA and DHA Mediated by HDL · The Miriam Hospital
Who these studies take
Of the 26 Lipid Metabolism Disorders studies recruiting now, 5 (19%) set no upper age limit and 19 (73%) stop at 75 or younger. 4 (15%) take children under 18. 1 (4%) are for women only and 1 (4%) for men only; 10 (38%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (8%) | 2 (8%) |
| 18 | 20 (77%) | 21 (81%) |
| 30 | 20 (77%) | 21 (81%) |
| 40 | 20 (77%) | 20 (77%) |
| 50 | 21 (81%) | 21 (81%) |
| 65 | 19 (73%) | 19 (73%) |
| 75 | 10 (38%) | 10 (38%) |
| 85 | 5 (19%) | 6 (23%) |
Across all 177 studies, recruiting or not: 55% stop at 75 or younger and 40% at 65; 14% take children; 7% are for women only and 7% for men only; 48% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Lipid Metabolism Disorders studies take
Of 13 phase 2 interventional studies under Lipid Metabolism Disorders, half reached primary completion within 19 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 19 mo12–30 · 13 studies | — | — |
| Interventional, no phase | 14 mo6–31 · 46 studies | — | 15 mo6–71 · 39 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 177. Browse all 177 → or search them.
- Plasma Lipids-Dependent Vitamin E Metabolism During Dynamic HyperlipidemiaNot yet recruitingNCT07715890Not applicable1 country
- Impact of MBS on Body Composition, Basal Metabolic Rates and Muscle Functions in Morbid Obese PatientsRecruitingNCT077378601 country
- Late Subclinical Cardiovascular Disease in Testicular Cancer SurvivorsRecruitingNCT056113071 country
- Study of Zodasiran in Adolescent Participants With Homozygous Familial HypercholesterolemiaRecruitingNCT07473843Phase 33 countries
- EDIT-401 in Adults Who Require Additional Lowering of Low-Density Lipoprotein Cholesterol (LDL-C)Not yet recruitingNCT07894887Phase 1/21 country
- Metabolic Effects of an Ophiocordyceps Sinensis- and CoQ10-Based Formulation in Mild-to-Moderate HypercholesterolemiaNot yet recruitingNCT07852481Not applicable
- A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory DyslipidemiasRecruitingNCT07491172Phase 14 countries
- Assessing the Impact of Intensification of Lipid Lowering Therapy With Guidelines-based Evinacumab Administration on Coronary Plaque Volumes Measured by Coronary Computed Tomography Angiography (CCTA) in Patients With Homozygous Familial Hypercholesterolemia (HoFH)RecruitingNCT074476484 countries
- Bao Yuan Tang Extract and Galactooligosaccharides for Sleep RegulationNot yet recruitingNCT07774897Not applicable1 country
- Screening for Disorders of Lipid Metabolism and Familial Hyperlipidemia in Children and Adolescents With Increased Cardiovascular Risk Due to Chronic Diseases Such as Congenital Heart Disease, Chronic Inflammatory Bowel Disease, Celiac Disease and Rheumatic DisordersRecruitingNCT07716488Not applicable1 country
- Effect of Ilex Paraguariensis Harvest Time and Consumption Method of Processed Yerba Mate on the Lipid ProfileRecruitingNCT06896175Not applicable1 country
- Metabolism and Sleep Apnea TreatmentRecruitingNCT05539716Not applicable1 country
- Multicomponent Intervention Study- Blood Donors With High CholesterolRecruitingNCT05693701Not applicable1 country
- Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders TrialRecruitingNCT06488105Phase 21 country
- Comorbidities Resolution After MGB Surgery and Change in Body CompositionRecruitingNCT060156201 country
- Lipoprotein Interactions and Platelet Function in Healthy Individuals and Those With Lipid DisordersRecruitingNCT067470001 country
- Differential Thrombogenesis by EPA and DHA Mediated by HDLRecruitingNCT06494488Early Phase 11 country
- "Perfect Heartio" Drink and Cardiovascular HealthRecruitingNCT07048158Not applicable1 country
- Heart CT Imaging to Detect Early Coronary Artery Disease in First-Degree Relatives With High or Low Lipoprotein(a) Identified Through Family ScreeningRecruitingNCT069951831 country
- Efficacy of Probucol Combined with Statins Treatment for Ischemic StrokeRecruitingNCT066041171 country
- Postprandial Metabolome and Metabolic FlexibilityRecruitingNCT06878781Not applicable1 country
- Impact of Chromium Supplementation on Glucido-lipidic Metabolism, Oxidative Stress and Inflammatory State in Patients with Gestational DiabetesNot yet recruitingNCT06860087Phase 1/21 country
- 4D-310 in Adults With Fabry Disease and Cardiac InvolvementRecruitingNCT05629559Phase 1/22 countries
- Efficacy of Lipid-Lowering Therapy Based on Apolipoprotein B Versus LDL-Cholesterol Levels in Patients Undergoing Percutaneous Coronary InterventionNot yet recruitingNCT06626126Not applicable1 country
- Th Tl Xb Prescription on Reprogramming of Lipid Metabolism and Endothelial Injury for Cerebral Infarction PatientsNot yet recruitingNCT06549582Not applicable
- Cardiovascular-Renal Adverse Prognosis Assessment System for Coronary Heart Disease With Chronic Kidney Disease Based on MetabolomicsRecruitingNCT063832081 country
- Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant PatientsNot yet recruitingNCT06381947Phase 4
- Metabolic Flexibility and Autonomic Control After Muscle Power vs Metabolic Power Training in Postmenopausal Oncological Women: the POWER Health StudyRecruitingNCT06336070Not applicable1 country
- Preventing Exercise Resistance With Sedentary InterruptionsRecruitingNCT06277713Not applicable1 country
- Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale CanadaRecruitingNCT020093451 country
- Multidisciplinary Design to Optimize Schizophrenia Treatment Based on Multi-omics Data and Systems Biology AnalysisNot yet recruitingNCT06060886Phase 4
- The Atherogenic Index of Plasma(AIP) in Patients With Atrial FibrillationNot yet recruitingNCT05973474
- Short-term Fat Overfeeding on the Effects of Liver MetabolismRecruitingNCT05962190Not applicable1 country
- Effects of GLP-1RA on Body Weight, Metabolism and Fat Distribution in Overweight/Obese Patients With Type 2 Diabetes MellitusRecruitingNCT05779644Not applicable1 country
- Impact of Foods on Bile Acids, Metabolites, and InflammationRecruitingNCT05245357Not applicable1 country
- The Biological Rhythm of Human MetaboliteRecruitingNCT036698091 country
- Genes Involved in Lipid DisordersCompletedNCT023113351 country
- Gene Transfer Clinical Trial for Infantile and Late Infantile Krabbe Disease Treated Previously With HSCTActive, not recruitingNCT05739643Phase 1/21 country
- Evaluation of the Effect of Lomitapide Treatment on Major Adverse Cardiovascular Events (MACE) in Patients With Homozygous Familial HypercholesterolemiaActive, not recruitingNCT068323715 countries
- Causal Mechanisms in Adolescent Arterial StiffnessCompletedNCT04128969Phase 21 country
- EMERALD (Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders)CompletedNCT05742841Phase 41 country
- The Effect of a Meatless,Keto Restrictive Diet on Body Composition,Strength Capacity,Oxidative Stress,Immune ResponseCompletedNCT05558488Not applicable1 country
- A Study to Evaluate the Efficacy and Safety of CBL-514 Compared to Placebo in Participants With Dercum's Disease LipomasCompletedNCT06303570Phase 21 country
- Polypill in Acute Coronary SyndromeCompletedNCT05514938Phase 21 country
- Feasibility & Implementation of a Plant-Based Weight-Loss Program in an Office-Based SettingCompletedNCT04091516Not applicable1 country
- Effect of Plasma Ceramides on Peripheral Vascular FunctionCompletedNCT05107869Not applicable1 country
- To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe HypertriglyceridemiaCompletedNCT05852431Phase 320 countries
- A Study of NatureU Burn on Satiety in Healthy AdultsCompletedNCT07597382Not applicable1 country
- The Very Large Database of LipidsActive, not recruitingNCT016984891 country
- Impact of Phytosterol-Rich Extract on Lipid ProfileCompletedNCT06657456Not applicable1 country