SupplementDrug
Eicosapentaenoic Acid clinical trials
Also written EPA.
- studies test it
- 56
- open now
- 6
- in phase 3
- 13
- first study started
- 2000
Keep track of what changes. Save the Eicosapentaenoic Acid studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
- ALFA
- 6
Studies by the year they started
56 studies that test it; most in 2025 (6)
| Year | Studies |
|---|---|
| 2000 | 1 |
| 2003 | 1 |
| 2005 | 3 |
| 2006 | 4 |
| 2007 | 4 |
| 2008 | 1 |
| 2009 | 2 |
| 2010 | 1 |
| 2011 | 4 |
| 2012 | 3 |
| 2013 | 4 |
| 2014 | 4 |
| 2015 | 2 |
| 2016 | 3 |
| 2017 | 1 |
| 2018 | 3 |
| 2019 | 3 |
| 2020 | 2 |
| 2021 | 1 |
| 2023 | 1 |
| 2024 | 2 |
| 2025 | 6 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 1
- Phase 2
- 9
- Phase 3
- 13
- Phase 4
- 9
- No phase
- 26
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 10 · Other 46
S.L.A. Pharma AG (4) · National Science and Technology Council, Taiwan (3) · Massachusetts General Hospital (2) · Mochida Pharmaceutical Company, Ltd. (2) · Tehran University of Medical Sciences (2) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (2) · William Coryell (2) · CHU de Quebec-Universite Laval (1)
Often tested with
Tested in the same studies.
Docosahexaenoic Acids (19) · Beta-hydroxyisovaleric acid (2) · Flavonoids (1) · Megestrol Acetate (1) · Megestrol (1) · Lutein (1) · Zeaxanthins (1) · Vitamin E (1)
Studies
Open first, then newest update. How each study uses Eicosapentaenoic Acid is read from its arms, and is right about nine times in ten.
Testing it · 56
- Lifestyle Interventions to Prevent cOgnitive Deficits in Subjects With Depressive Symptoms: From mEchanisms to Clinical pRacticeRecruitingNot applicableNational Science and Technology Council, TaiwanNCT07462013Written as Eicosapentaenoic acid (omega-3 fatty acid)
- Observing Metabolism of EPA With Consideration of Genetics And SexRecruitingPhase 4University of TorontoNCT06975241Written as EPA 2.4g/day
- NUTRIMOOD-Inflammation and Depressive Comorbidity in Obesity: Modulation by Omega-3 Polyunsaturated Fatty Acids StatusRecruitingNot applicableNational Science and Technology Council, TaiwanNCT07439744Written as Eicosapentaenoic acid (omega-3 fatty acid)
- Differential Thrombogenesis by EPA and DHA Mediated by HDLRecruitingEarly Phase 1The Miriam HospitalNCT06494488Written as EPA
- The Developmental Origins of ObesityRecruitingNot applicablePontificia Universidad Catolica de ChileNCT06981676Written as DHA and EPA
- Impact of "Targeted" Nutritional Apport and Exercise on the Modulation of Metabolic and Immune-related Gene Expression Signatures in Early Breast Cancer (eBC) Patients Candidate to Neoadjuvant Therapy (NAT)RecruitingNot applicableUniversity of Eastern PiedmontNCT06928701Written as omega-3 (n-3 Lc-PUFA), EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) plus a source of palmitoleic acid (hexadecenoic acid)
- Effects of EPA on Prostate Cancer Cells Proliferation and Quality of LifeActive, not recruitingPhase 2CHU de Quebec-Universite LavalNCT02333435Written as EPA
- The Efficacy of Long-Chain Fatty Acids, Eicosapentaenoic Acid (EPA) and Specialized Pro-Resolving Mediators (SPMs), in Treating Long COVID Neuropsychiatric SymptomsCompletedNot applicableNational Science and Technology Council, TaiwanNCT07711444Written as Eicosapentaenoic acid (omega-3 fatty acid)
- Impact of Omega-3 Fatty Acid Oral Therapy on Healing of Chronic Venous Leg Ulcers in Older AdultsCompletedNot applicableOhio State UniversityNCT03576989Written as EPA+DHA
- Exploring Sustainable Alternatives to Marine Oils With Echium and Ahiflower OilsActive, not recruitingNot applicableUniversity of Sao PauloNCT07289919Written as EPA capsules
- Cardiometabolic Properties of Omega-3 Functionalized With HydroxytyrosolActive, not recruitingNot applicableNational Research Council, SpainNCT06992323Written as EPA
- Effect of EPA-FFA on Polypectomy in Familial Adenomatous PolyposisActive, not recruitingPhase 3S.L.A. Pharma AGNCT03806426Written as Eicosapentaenoic acid free fatty acid (EPA-FFA)
- Dose Response Effects of Marine Omega-3 Fatty Acids on InflammationCompletedPhase 3Penn State UniversityNCT01078909Written as Eicosapentaenoic Acid and Docosahexaenoic Acid (EPA + DHA)
- Omega -3 Fatty Acid in Combination With Tyrosine Kinase Inhibitors in Chronic Myeloid LeukemiaTerminatedPhase 1/2Milton S. Hershey Medical CenterNCT04006847Written as Eicosapentaenoic Acid
- Omega-3 Fatty Acids for Major Depressive Disorder With High Inflammation: A Personalized ApproachCompletedPhase 2/3Massachusetts General HospitalNCT02553915Written as EPA 1 g/day
- Impact of Fish Oil Monoglycerides on the Modulation of Mitochondrial Functions and Lactate ThresholdTerminatedPhase 4Samuel FortinNCT03915535Written as Eicosapentaenoic acid + Docosahexaenoic acid
- EPA-FFA to Treat Hospitalised Patients With COVID-19 (SARS-CoV-2)Status unknownPhase 3S.L.A. Pharma AGNCT04335032Written as Eicosapentaenoic acid gastro-resistant capsules
- Long-term Safety and Efficacy Study of MND-2119 in Patients With HypertriglyceridemiaCompletedPhase 3Mochida Pharmaceutical Company, Ltd.NCT04221217Written as Icosapent
- The Protective Effect of Omega-3 Fatty Acid on Cognitive Function Among Patients With Mild DementiaCompletedNot applicableTaichung Veterans General HospitalNCT04972643Written as EPA
- Role of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) on Inflammation and LipidsCompletedNot applicableTufts UniversityNCT02670382Written as EPA
See all 56 studies that test Eicosapentaenoic Acid →
Given in every arm · 3 — Eicosapentaenoic Acid is usual care beside what is tested
- Dietary Essential Fatty Acid Regulation of Omega-3 HUFA Metabolism; Satiety and Body CompositionCompletedNot applicableNational Institute on Alcohol Abuse and Alcoholism (NIAAA)NCT01251887Written as Eicosapentaenoic Acid
- Effects of High-dose n-3 Fatty Acids on Clinical Outcome and Serum Lipids - Omacor Following Acute Myocardial InfarctionCompletedPhase 3Helse Stavanger HFNCT01422317Written as EPA / DHA / Alpha-Tocopherol
- Omega-3 Fatty Acid Deficiency Replacement in Early SchizophreniaCompletedPhase 2/3University of CincinnatiNCT00585390Written as EPA fish oil concentrate; DHA fish oil concentrate
As the comparator · 2 — what is tested is compared with Eicosapentaenoic Acid
- Effect of Rosuvastatin and Eicosapentaenoic Acid on Neoatherosclerosis: The LINK-IT TrialCompletedPhase 4Kobe UniversityNCT03192579Written as EPA and high dose rosuvastatin
- Time and Dose Evaluation of Stearidonic Acid (SDA) to Eicosapentaenoic Acid (EPA) in Red Blood CellsCompletedNot applicableSolae, LLCNCT01038440Written as EPA
Codes
What other systems call Eicosapentaenoic Acid · ClinicalTrials.gg INT008440
- MeSH (NLM) D015118Eicosapentaenoic AcidConfirmed NLM, Wikidata
- UNII (FDA) AAN7QOV9EAICOSAPENTConfirmed FDA, NLM, Wikidata
- RxNorm 90Confirmed FDA, Wikidata
- Wikidata Q409990eicosapentaenoic acidConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C68434IcosapentConfirmed FDA, Wikidata
- DrugBank DB00159One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D015118 | Eicosapentaenoic Acid | Confirmed NLM, Wikidata |
| UNII (FDA) | AAN7QOV9EA | ICOSAPENT | Confirmed FDA, NLM, Wikidata |
| RxNorm | 90 | — | Confirmed FDA, Wikidata |
| Wikidata | Q409990 | eicosapentaenoic acid | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C68434 | Icosapent | Confirmed FDA, Wikidata |
| DrugBank | DB00159 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.