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Hypertension, Pulmonary clinical trials

The registry lists 1,091 studies for Hypertension, Pulmonary across more than 10 countries. 243 are recruiting or about to start. 635 of them are mainly about Hypertension, Pulmonary (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12. Counting its 4 narrower conditions too, such as Pulmonary Arterial Hypertension: 1,682 studies, 369 open.

ClinicalTrials.gov finds 2,100 studies for Hypertension, Pulmonary. How that becomes 1,092 here

This page counts the studies the registry files under Hypertension, Pulmonary, and those it files under no condition that list Hypertension, Pulmonarythemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 2,100Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −591Filed under a narrower condition, counted on its own pagePulmonary Arterial Hypertension 507 · Cirrhosis, Familial, with Pulmonary Hypertension 37 · Persistent Fetal Circulation Syndrome 33 · Pulmonary edema of mountaineers 8
  3. −52List Hypertension, Pulmonary as a condition, but the registry did not file them under itMost often written as “Chronic Thromboembolic Pulmonary Hypertension” (19), “Pulmonary Hypertension of Newborn” (4), and “Persistent Pulmonary Hypertension” (3). The registry filed them under other conditions only, most often Heart Failure (8) and Pulmonary Embolism (8).
  4. −365Match it another way69 name it in the title, 7 in a keyword, and 289 by a synonym or other text the search reads.
  5. 1,092The count on this page73 of them list Hypertension, Pulmonary in their own words; the registry filed them under no condition.

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Status

Completed
517
Recruiting
163
Status unknown
125
Terminated
120
Not yet recruiting
62
Withdrawn
49

Phase

Phase 2
191
Phase 3
142
Phase 4
76
Phase 1
71
Early Phase 1
13

Where

United States
397
Germany
150
United Kingdom
117
France
108
Canada
94
China
85

Who runs them

University of Zurich (55) · Bayer (38) · United Therapeutics (34) · Actelion (28) · Medical University of Graz (19) · National Heart, Lung, and Blood Institute (NHLBI) (16) · Assiut University (15) · Assistance Publique - Hôpitaux de Paris (15)

What is being tested here

Drugs under test in Hypertension, Pulmonary studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Treprostinil41535
Tadalafil3917
Nitric Oxide2621
Sotatercept225
Mosliciguat214
Treprostinil hexadecyl ester234
Norepinephrine202
Sildenafil11948
Macitentan136
Selexipag135

Drug classes tested here PDE5 inhibitors 4 open · Endothelin receptor antagonists 1 open · Bronchodilators 1 open · Diuretics 9 · Tyrosine kinase inhibitors (TKIs) 6

Coming up

17phase 3 studies under way
66studies finish main data collection within a year3 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 163 Hypertension, Pulmonary studies recruiting now, 99 (61%) set no upper age limit and 26 (16%) stop at 75 or younger. 39 (24%) take children under 18. 3 (2%) are for women only and 0 (0%) for men only; 24 (15%) take healthy volunteers.

Recruiting studies that take each age, of 163
AgeWomenMen
1027 (17%)27 (17%)
18146 (90%)143 (88%)
30147 (90%)144 (88%)
40151 (93%)148 (91%)
50151 (93%)148 (91%)
65147 (90%)146 (90%)
75144 (88%)143 (88%)
85122 (75%)121 (74%)

Across all 1,091 studies, recruiting or not: 23% stop at 75 or younger and 14% at 65; 22% take children; 1% are for women only and 1% for men only; 12% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Hypertension, Pulmonary studies take

Of 50 phase 2 interventional studies under Hypertension, Pulmonary, half reached primary completion within 44 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 119 mo15–39 · 21 studies——
Phase 244 mo25–71 · 50 studies——
Phase 352 mo30–83 · 31 studies——
Phase 442 mo21–54 · 23 studies——
Interventional, no phase23 mo9–48 · 148 studies—20 mo9–46 · 134 studies
Observational59 mo24–107 · 167 studies—60 mo24–167 · 142 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting2

Results posted1

Stopped1

Newly registered8

Show 3 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,091. Browse all 1,091 → or search them.