Drug
Treprostinil clinical trials
Also written Tyvaso, Remodulin, UT-15C and UT-15.
- studies test it
- 100
- open now
- 13
- in phase 3
- 33
- first study started
- 1998
Keep track of what changes. Save the treprostinil studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
100 studies that test it; most in 2017 (9)
| Year | Studies |
|---|---|
| 1998 | 1 |
| 2002 | 1 |
| 2003 | 2 |
| 2005 | 3 |
| 2006 | 4 |
| 2007 | 3 |
| 2008 | 7 |
| 2009 | 6 |
| 2010 | 8 |
| 2011 | 1 |
| 2012 | 8 |
| 2013 | 3 |
| 2014 | 2 |
| 2015 | 6 |
| 2016 | 6 |
| 2017 | 9 |
| 2018 | 6 |
| 2019 | 6 |
| 2020 | 2 |
| 2021 | 2 |
| 2022 | 3 |
| 2023 | 3 |
| 2025 | 4 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 19
- Phase 2
- 30
- Phase 3
- 33
- Phase 4
- 19
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 72 · Other 28
United Therapeutics (60) · Liquidia Technologies, Inc. (6) · Stanford University (3) · Eli Lilly and Company (2) · Brigham and Women's Hospital (2) · University of Florida (1) · Mayo Clinic (1) · Guangzhou Institute of Respiratory Disease (1)
Often tested with
Tested in the same studies.
Sodium Citrate (1) · Magnesium Chloride (1) · Zamicastat (1) · Insulin Lispro (1) · Iloprost (1)
Studies
Open first, then newest update. How each study uses treprostinil is read from its arms, and is right about nine times in ten.
Testing it · 100
- Extension Study of Inhaled Treprostinil in Subjects With Fibrotic Lung DiseaseEnrolling by invitationPhase 3United TherapeuticsNCT04905693Written as Inhaled Treprostinil
- A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILDRecruitingPhase 3Liquidia Technologies, Inc.NCT07285655Written as L606
- A Study of Inhaled Treprostinil (LIQ861) in Adults With Pulmonary Arterial Hypertension Transitioning From Oral SelexipagRecruitingPhase 4Liquidia Technologies, Inc.NCT07759804Written as LIQ861 (treprostinil) inhalation powder
- Early Intervention With Inhaled Treprostinil Among Patients With Exercise-Induced Pulmonary Hypertension (EPIH)RecruitingEarly Phase 1Valley Health SystemNCT07837830Written as Treprostinil
- Inhaled Treprostinil (Tyvaso Nebulizer) For COPD Patients With HypoxemiaRecruitingPhase 2Bastiaan DriehuysNCT07037836Written as Inhaled Treprostinil (Tyvaso Nebulizer)
- A Study of LIQ861 (Inhaled Treprostinil) in Adults With Systemic Sclerosis Who Have Symptomatic Raynaud's Phenomenon AttacksNot yet recruitingPhase 2Liquidia Technologies, Inc.NCT07748000Written as LIQ861 (treprostinil) inhalation powder - Dose Titration Arm
- Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)RecruitingPhase 3United TherapeuticsNCT05943535Written as Inhaled Treprostinil
- Safety and Efficacy of Treprostinil (Remodulin®) In Reducing Ischemia-Reperfusion Injury During Kidney TransplantationRecruitingPhase 1/2Rhode Island HospitalNCT04005469Written as Treprostinil
- Open Label Treprostinil Raynaud's StudyRecruitingPhase 4Brigham and Women's HospitalNCT07112183Written as Oral treprostinil (UT-15C) sustained release tablets
- Efficacy and Safety of Treprostinil in Intermediate-Risk Pulmonary Arterial HypertensionNot yet recruitingPhase 2Shanghai Zhongshan HospitalNCT07177703Written as Treprostinil
- Effects of Inhaled Treprostinil on Exercise Performance in Exercise Induced Pulmonary HypertensionNot yet recruitingEarly Phase 1University of California, San DiegoNCT07116681Written as Inhaled treprostinil
- Trial to Evaluate Parenteral Treprostinil and Riociguat on Right Ventriculo-vascular Coupling and Morphology in Those With Advanced PAHRecruitingPhase 3University of ArizonaNCT04062565Written as Treprostinil Injectable Product
- Effects of Treprostinil on Right Ventricular Structure and Function in Patients With Pulmonary Arterial HypertensionRecruitingPhase 4Magdi H. YacoubNCT03835676Written as Treprostinil
- Multinational Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary FibrosisCompletedPhase 3United TherapeuticsNCT05255991Written as Inhaled Treprostinil
- Inhaled Treprostinil in Participants With Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease (PH-COPD)TerminatedPhase 3United TherapeuticsNCT03794583Written as Inhaled treprostinil solution
- Study of Efficacy and Safety of Inhaled Treprostinil in Subjects With Idiopathic Pulmonary FibrosisCompletedPhase 3United TherapeuticsNCT04708782Written as Inhaled Treprostinil
- Inhaled Treprostinil in Sarcoidosis Patients With Pulmonary HypertensionCompletedPhase 2University of FloridaNCT03814317Written as Inhaled Treprostinil
- A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial HypertensionActive, not recruitingPhase 4United TherapeuticsNCT05203510Written as Parenteral Treprostinil
- A Study of Treprostinil to Treat Interstitial Lung Disease Pulmonary HypertensionCompletedPhase 2Mayo ClinicNCT05564637Written as Treprostinil
- Safety, Tolerability, and Pharmacokinetics of Oral Treprostinil in Pediatric PAH Patients Aged 7 to 17 YearsCompletedPhase 2United TherapeuticsNCT02276872Written as oral treprostinil
Codes
What other systems call treprostinil · ClinicalTrials.gg INT004347
- MeSH (NLM) C427248treprostinilConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) RUM6K67ESGTREPROSTINILConfirmed FDA, NLM, Wikidata
- RxNorm 343048Confirmed FDA, Wikidata
- Wikidata Q3495231treprostinilConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61983TreprostinilOne source FDA
- DrugBank DB00374One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C427248 | treprostinil | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | RUM6K67ESG | TREPROSTINIL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 343048 | — | Confirmed FDA, Wikidata |
| Wikidata | Q3495231 | treprostinil | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61983 | Treprostinil | One source FDA |
| DrugBank | DB00374 | — | One source Wikidata |
Also registered as treprostinil diolamine (UNII H1FKG90039 · RxNorm 1927409) and treprostinil sodium (UNII 7JZ75N2NT6 · RxNorm 342691).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.