Drug
Nitric Oxide clinical trials
Also written INOmax.
- studies test it
- 141
- open now
- 12
- in phase 3
- 36
- first study started
- 1995
Keep track of what changes. Save the Nitric Oxide studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Development codes
Combined with it in one product
Studies by the year they started
141 studies that test it; most in 2020 (10)
| Year | Studies |
|---|---|
| 1995 | 1 |
| 1998 | 2 |
| 1999 | 1 |
| 2000 | 2 |
| 2001 | 3 |
| 2002 | 3 |
| 2003 | 1 |
| 2004 | 4 |
| 2005 | 7 |
| 2006 | 4 |
| 2007 | 2 |
| 2008 | 5 |
| 2009 | 7 |
| 2010 | 4 |
| 2011 | 6 |
| 2012 | 6 |
| 2013 | 5 |
| 2014 | 2 |
| 2015 | 5 |
| 2016 | 9 |
| 2017 | 8 |
| 2018 | 6 |
| 2019 | 7 |
| 2020 | 10 |
| 2021 | 5 |
| 2022 | 3 |
| 2023 | 9 |
| 2024 | 6 |
| 2025 | 3 |
| 2026 | 5 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 9
- Phase 1
- 25
- Phase 2
- 73
- Phase 3
- 36
- Phase 4
- 7
- No phase
- 14
What it is tested for
Each study’s main condition, where its own words name it.
- COVID-19
- 11
Who runs them
Industry 43 · Other 98
Mallinckrodt (15) · Massachusetts General Hospital (9) · Bellerophon Pulse Technologies (6) · Tomsk National Research Medical Center of the Russian Academy of Sciences (5) · Sanotize Research and Development corp. (5) · Beyond Air Inc. (5) · Wake Forest University Health Sciences (4) · University of Alberta (4)
Often tested with
Tested in the same studies.
Oxygen (1) · Epoprostenol (1) · Nitroglycerin (1) · Methylene Blue (1) · Carbon Monoxide (1) · Helium (1)
Studies
Open first, then newest update. How each study uses Nitric Oxide is read from its arms, and is right about nine times in ten.
Testing it · 141
- NO During CPB in Neonates to Reduce Risk of AKIRecruitingPhase 3Children's Hospital Medical Center, CincinnatiNCT04216927Written as Nitric Oxide
- The Effect of Inhaled Nitric Oxide on Pulmonary Gas-exchange in COPDNot yet recruitingPhase 1/2University of AlbertaNCT04231760Written as Inhaled Nitric Oxide
- Inhaled Nitric Oxide for Microvascular Dysfunction in Traumatic Brain InjuryEnrolling by invitationPhase 2University of PennsylvaniaNCT05616910Written as inhaled nitric oxide
- Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary BypassRecruitingPhase 3Xijing HospitalNCT06702553Written as Nitric Oxide Gas
- iNO300 Therapy in Critically Ill Patients With PneumoniaRecruitingEarly Phase 1Massachusetts General HospitalNCT06950294Written as High dose inhaled nitric oxide
- Inhaled Nitric Oxide in Acute Ischemic Stroke Patients Undergoing Mechanical ThrombectomyRecruitingPhase 1Wake Forest University Health SciencesNCT05871606Written as iNO
- Inhaled Nitric Oxide for Prevention of Postoperative AKI in High-Risk Cardiac Surgery PatientsNot yet recruitingNot applicableShanghai Zhongshan HospitalNCT07544147Written as Inhaled Nitric Oxide (iNO)
- Efficacy of Inhaled Nitric Oxide in Congenital Diaphragmatic HerniaNot yet recruitingPhase 4Asan Medical CenterNCT07247240Written as Inhaled Nitric Oxide
- Inhaled Nitric Oxide (iNO) in Idiopathic Pulmonary Fibrosis (IPF).RecruitingEarly Phase 1Dr. Denis O'DonnellNCT05052229Written as Nitric Oxide
- Role of Inhaled Nitric Oxide in Vascular Mechanics and Right Ventricular FunctionRecruitingNot applicableFernando Suarez SipmannNCT06097026Written as Nitric Oxide
- Inhaled Nitric Oxide for ARDS-related Pulmonary HypertensionNot yet recruitingEarly Phase 1Yuri MatusovNCT06249633Written as Nitric Oxide
- The Effects of a Nitrate Supplementation on Erectile FunctionRecruitingNot applicableRHA Investments LtdNCT06213077Written as Nitric Oxide
- Perioperative Nitric Oxide Prevents Acute Kidney Injury in Cardiac Surgery Patients With Chronic Kidney DiseaseCompletedPhase 1/2Tomsk National Research Medical Center of the Russian Academy of SciencesNCT05757557Written as 80-ppm NO
- Nitric Oxide in Cardiopulmonary Bypass for Renal Protection in Cardiac SurgeryCompletedPhase 1/2Nikolay KamenshchikovNCT03527381Written as Nitric Oxide
- Nitric Oxide-mediated Cardioprotection During Cardiac Surgery With Cardiopulmonary BypassCompletedPhase 1/2Tomsk National Research Medical Center of the Russian Academy of SciencesNCT03500783Written as Nitric Oxide
- High-dose Inhalations of Nitric Oxide in the Treatment of PneumoniaActive, not recruitingNot applicableTomsk National Research Medical Center of the Russian Academy of SciencesNCT06170372Written as 200 ppm Nitric Oxide
- High-dose Inhaled NO Therapy for the Prevention of Nosocomial Pneumonia After Cardiac Surgery With CPBCompletedNot applicableTomsk National Research Medical Center of the Russian Academy of SciencesNCT06162455Written as 200- ppm NO
- High-dose Inhaled NO Therapy for the pREvenvention of NP After Cardiac Surgery Under CPBCompletedNot applicableTomsk National Research Medical Center of the Russian Academy of SciencesNCT06261827Written as 200-ppm NO
- Nitric Oxide Gas Inhalation in Severe Acute Respiratory Syndrome in COVID-19CompletedPhase 2Massachusetts General HospitalNCT04306393Written as Nitric Oxide Gas
- Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19TerminatedPhase 2Massachusetts General HospitalNCT04305457Written as Nitric Oxide
See all 141 studies that test Nitric Oxide →
Given in every arm · 1 — Nitric Oxide is usual care beside what is tested
Codes
What other systems call Nitric Oxide · ClinicalTrials.gg INT007899
- MeSH (NLM) D009569Nitric OxideConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 31C4KY9ESHNITRIC OXIDEConfirmed FDA, NLM, Wikidata
- RxNorm 7442Confirmed FDA, Wikidata
- Wikidata Q207843nitric oxideConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C695Nitric OxideOne source FDA
- DrugBank DB00435One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D009569 | Nitric Oxide | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 31C4KY9ESH | NITRIC OXIDE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 7442 | — | Confirmed FDA, Wikidata |
| Wikidata | Q207843 | nitric oxide | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C695 | Nitric Oxide | One source FDA |
| DrugBank | DB00435 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.