Drug
Tadalafil clinical trials
Also written Cialis, LY450190 and IC351.
- studies test it
- 193
- open now
- 21
- in phase 3
- 53
- first study started
- 2001
Keep track of what changes. Save the Tadalafil studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
- Cialis
- 81
Development codes
Studies by the year they started
191 studies that test it; most in 2022 (15)
| Year | Studies |
|---|---|
| 2001 | 1 |
| 2002 | 2 |
| 2003 | 9 |
| 2004 | 6 |
| 2005 | 7 |
| 2006 | 6 |
| 2007 | 2 |
| 2008 | 6 |
| 2009 | 12 |
| 2010 | 12 |
| 2011 | 11 |
| 2012 | 8 |
| 2013 | 7 |
| 2014 | 11 |
| 2015 | 8 |
| 2016 | 7 |
| 2017 | 9 |
| 2018 | 1 |
| 2019 | 4 |
| 2020 | 6 |
| 2021 | 10 |
| 2022 | 15 |
| 2023 | 6 |
| 2024 | 9 |
| 2025 | 11 |
| 2026 | 5 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 5
- Phase 1
- 33
- Phase 2
- 49
- Phase 3
- 53
- Phase 4
- 48
- No phase
- 18
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 72 · Other 121
Eli Lilly and Company (49) · Beni-Suef University (6) · Mansoura University (5) · Cedars-Sinai Medical Center (5) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (4) · Actelion (4) · Mayo Clinic (4) · Ain Shams University (3)
Often tested with
Tested in the same studies.
Sildenafil (12) · Tamsulosin (9) · Macitentan (7) · Mirabegron (3) · Ambrisentan (3) · Pembrolizumab (2) · Solifenacin (2) · Pentoxifylline (2)
Studies
Open first, then newest update. How each study uses Tadalafil is read from its arms, and is right about nine times in ten.
Testing it · 193
- Multimodal Prehabilitation and Rehabilitation for Men Undergoing Robot-Assisted Radical ProstatectomyRecruitingPhase 2Surgical Outcomes Research Centre (SOuRCe)NCT07576335Written as Tadalafil 5 mg
- Effects of Tadalafil on Cognition and Cerebral Hemodynamics in Elderly Patients With Mild Cognitive ImpairmentNot yet recruitingPhase 2Los Angeles Brain Science ProjectNCT07882901Written as Tadalafil 5 mg
- A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other OptionRecruitingPhase 3ActelionNCT05179876Written as Macitentan/Tadalafil FDC
- The Effects of Mirabegron and Tadalafil on Glucose Tolerance in PrediabeticsRecruitingPhase 4Philip KernNCT05051436Written as Tadalafil 10 MG
- Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary DiseaseRecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT05844462Written as Tadalafil
- Study of Tadalafil vs. Placebo for Improving Hemodynamics and End-Organ Dysfunction in Fontan PhysiologyRecruitingPhase 3Mayo ClinicNCT05206955Written as Tadalafil
- Tamsulosin With or Without Tadalafil for Trial Without Catheter After Acute Urinary Retention Due to Benign Prostatic HyperplasiaRecruitingPhase 4Beni-Suef UniversityNCT07654413Written as Tadalafil
- L-Citrulline and Tadalafil for Mild to Moderate Erectile DysfunctionRecruitingPhase 4Beni-Suef UniversityNCT07642505Written as Tadalafil
- Vasodilator and Exercise Study for DMD (VASO-REx)RecruitingPhase 2University of FloridaNCT06290713Written as Tadalafil
- Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PHRecruitingPhase 2VA Office of Research and DevelopmentNCT05937854Written as Tadalafil
- Effect of Tadalafil on Endometrial Thickness and Frozen Embryo Transfer OutcomesRecruitingPhase 4Beni-Suef UniversityNCT07499804Written as Tadalafil 5mg
- Tadalafil 5 mg on Storage Lower Urinary Tract Symptoms After Anatomical Endoscopic Enucleation of the ProstateNot yet recruitingPhase 1Assiut UniversityNCT07466030Written as Tadalafil 5mg (Male)
- Randomized Controlled Trial Comparing Low Dose Tadalafil Versus Solifenacin For Management of Overactive Bladder in Women: Multicenter Egyptian National StudyRecruitingPhase 4Mansoura UniversityNCT07416968Written as Tadalafil 5 mg
- Daily Tadalafil 5 mg Combined With On-Demand Sildenafil 100 mg for Treatment of Erectile Dysfunction in PDE-5I Non Responder PatientsRecruitingPhase 4Mansoura UniversityNCT07391579Written as Tadalafil 5 mg & Sildenafil 100mg
- Combination Therapy of Tadalafil 2.5mg Plus Sildenafil 25mg Versus Tadalafil 5 mg Monotherapy for Treatment of Erectile Dysfunction: A Randomized, Placebo-Controlled Double-Blinded Cross-Over StudyNot yet recruitingPhase 3Assiut UniversityNCT07177326Written as Tadalafil 2.5 mg
- Comparison of Sequential to Initial Combination Therapy in PAHRecruitingNot applicableSecond Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT06968962Written as Tadalafil
- Evaluation of Efficacy of Botulinum Toxin A Plus Oral Tadalafil 5 mg in Diabetic Men With Erectile DysfunctionRecruitingPhase 2/3Aswan University HospitalNCT06583590Written as Tadalafil 5mg
- Genetic Factors of Erectile Dysfunction Degree and Response to Tadalafil Treatment in Patients With DiabetesRecruitingPhase 3University Medical Centre LjubljanaNCT06520839Written as Tadalafil 5mg
- A Single Dose Randomized Five-Way Crossover Pharmacokinetics (PK) Study of Tadalafil Semi-Chewable (Gummy) Formulations in Healthy VolunteersNot yet recruitingPhase 1Seattle Gummy CompanyNCT04762082Written as Tadalafil 10 MG
- Effect of Tadalafil, Sildenafil and Pentoxyfylline on Frozen Embryo Transfer OutcomesNot yet recruitingPhase 2/3Beni-Suef UniversityNCT05971667Written as tadalafil
See all 193 studies that test Tadalafil →
Given in every arm · 16 — Tadalafil is usual care beside what is tested
- Daily Tadalafil as Adjunctive Therapy Versus Monotherapy for PDE5 Inhibitor-Resistant Erectile DysfunctionRecruitingPhase 4Al-Azhar UniversityNCT07753720Written as Tadalafil 5 mg
- Efficacy of Intracavernosal Xeomin With Tadalafil for Mild-Moderate Erectile DysfunctionNot yet recruitingPhase 2Northwestern UniversityNCT07537855Written as Tadalafil 20 MG
- Low-Intensity Extracorporeal Shockwave Therapy on Penile Rehabilitation After Robot-assisted Surgical Treatment of Genitourinary CancersRecruitingPhase 3Regina Elena Cancer InstituteNCT06717711Written as PDE5 inhibitor (tadalafil)
- COMMODITIES Trial: Initial Dual Oral Therapy vs Monotherapy in PAH With Cardiovascular ComorbiditiesRecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT07245680Written as Tadalafil
- The Effects of a Nitrate Supplementation on Erectile FunctionRecruitingNot applicableRHA Investments LtdNCT06213077Written as Tadalafil
- Dorsal Penile Nerve Cryoneurolysis for Lifelong PECompletedNot applicableBiruni UniversityNCT07879105Written as Tadalafil 5 mg
- PLEASURE (Pleasing Lovers, Efficacy, Arousal, Satisfaction, and Uptake Research on Eroxon)SuspendedPhase 4University of MiamiNCT07636161Written as tadalafil
- The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial HypertensionCompletedPhase 3ActelionNCT02558231Written as Tadalafil
- Evaluation of Tadalafil Combined With LIPUS for Treating Erectile DysfunctionCompletedNot applicableSecond Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT06543628Written as Tadalafil 5mg
- Bioequivalence Study of Macitentan and Tadalafil Film-coated Tablets 10 Mg/40 Mg and 'PrOpsynvi®' Macitentan and Tadalafil Film-coated Tablets 10 Mg/40 MgCompletedPhase 1Humanis Saglık Anonim SirketiNCT06553937Written as Macitentan and Tadalafil
- The Effect of Combination Therapy Using Li-ESWT and PDE-5 Inhibitor in Patients With Erectile DysfunctionCompletedNot applicableDr. Soetomo General HospitalNCT05043896Written as Tadalafil 2.5Mg Tab
- Safety and Pharmacokinetic Characteristics of DKF-313CompletedPhase 1Dongkook Pharmaceutical Co., Ltd.NCT02352311Written as CIALIS
- Observational Study of Pharmacological Treatment for Premature Ejaculation Concurrent With Erectile DysfunctionStatus unknownPhase 3Yan-Ping HuangNCT04361305Written as Tadalafil
- A 48-week Study of the Effect of Dual Therapy (Inhaled Treprostinil and Tadafafil) Versus Monotherapy (Tadalafil).CompletedPhase 4Stanford UniversityNCT01305252Written as tadalafil
- The Efficacy and Safety of the Combination of Tamsulosin and Tadalafil in Men With Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia and Erectile DysfunctionStatus unknownPhase 3IlDong Pharmaceutical Co LtdNCT02862483Written as Tadalafil 5mg
- Study of Add-on Ambrisentan Therapy to Background Phosphodiesterase Type-5 Inhibitor (PDE5i) Therapy in Pulmonary Arterial Hypertension (ATHENA-1)CompletedPhase 4Gilead SciencesNCT00617305Written as Tadalafil
As the comparator · 14 — what is tested is compared with Tadalafil
- Safety and Efficacy Evaluation of BZ371A Topically Applied on Prostatectomized PatientsRecruitingPhase 2Biozeus Biopharmaceutical S.A.NCT05558007Written as Tadalafil 5mg
- Efficacy and Safety of Toronto Association in the Treatment of Erectile Dysfunction and Premature EjaculationNot yet recruitingPhase 3EMSNCT05052879Written as Tadalafil
- Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)CompletedPhase 3ActelionNCT03904693Written as Tadalafil 40 mg
- Acute Haemodynamic Study of TPN171H in Patients with Pulmonary Arterial HypertensionCompletedPhase 2Vigonvita Life SciencesNCT04483115Written as Tadalafil
- Efficacy and Safety of DKF-313 in Patients With Benign Prostatic HyperplasiaCompletedPhase 3Dongkook Pharmaceutical Co., Ltd.NCT04947631Written as Tadalafil
- Shock Wave vs. On-demand Tadalafil for Erectile DysfunctionStatus unknownNot applicableMenoufia UniversityNCT05199727Written as Tadalafil 20Mg Oral Tablet
- Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapyCompletedPhase 4BayerNCT02891850Written as Tadalafil
- Combined Effect of Continuous and Interval in Addition to Tadalafil Drug on Erectile DysfunctionStatus unknownNot applicableCairo UniversityNCT04623840Written as Tadalafil 5Mg Tab
- Management of Prostatodynia in Younger Patients With Non-ablative Erbium:YAG Intraurethral LaserCompletedNot applicableAdrian GasparNCT04446598Written as Tadalafil 5mg
- A Bioavailability Study of LY2452473 and TadalafilCompletedPhase 1Eli Lilly and CompanyNCT01401543Written as Tadalafil
- Pharmacokinetics and Safety/Tolerability of YY-201 in Comparison to Dutasteride and TadalafilCompletedPhase 1Yuyu Pharma, Inc.NCT03240939Written as Tadalafil 5 mg
- Assessment of Efficacy of Vardenafil in Subjects With Erectile Dysfunction and Diabetes, Hypertension or HyperlipidemiaCompletedPhase 3BayerNCT00668109Written as Tadalafil
- Safety and Efficacy of YHD1023 in Erectile DysfunctionCompletedPhase 2Yuhan CorporationNCT01423370Written as Cialis
- Evaluating the Efficacy Vardenafil 10 mg vs Tadalafil 10 mg in in Subjects With Erectile Dysfunction (ED)CompletedPhase 4BayerNCT00663130Written as Tadalafil
Codes
What other systems call Tadalafil · ClinicalTrials.gg INT006522
- MeSH (NLM) D000068581TadalafilConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 742SXX0ICTTADALAFILConfirmed FDA, NLM, Wikidata
- RxNorm 358263Confirmed FDA, Wikidata
- Wikidata Q424156tadalafilConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47743TadalafilOne source FDA
- DrugBank DB00820One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D000068581 | Tadalafil | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 742SXX0ICT | TADALAFIL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 358263 | — | Confirmed FDA, Wikidata |
| Wikidata | Q424156 | tadalafil | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47743 | Tadalafil | One source FDA |
| DrugBank | DB00820 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.