Corneal Diseases clinical trials
The registry lists 219 studies for Corneal Diseases across more than 10 countries. 43 are recruiting or about to start. 96 of them are mainly about Corneal Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09. Counting its 15 narrower conditions too, such as Keratoconus: 1,045 studies, 189 open.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
National Eye Institute (NEI) (9) · Kissei Pharmaceutical Co., Ltd. (8) · National Taiwan University Hospital (4) · Tufts Medical Center (4) · Daniela Nosch (4) · Benha University (4) · Federal University of São Paulo (4) · Massachusetts General Hospital (4)
What is being tested here
Drugs under test in Corneal Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexamethasone | 4 | 0 | 5 |
| Daratumumab | 2 | 0 | 2 |
| Lenalidomide | 2 | 0 | 2 |
| Riboflavin | 1 | 4 | 5 |
| Fluorometholone | 1 | 0 | 2 |
| Pomalidomide | 1 | 0 | 1 |
| Nirogacestat | 1 | 0 | 1 |
| Ozagrel | 0 | 3 | 7 |
| Moxifloxacin | 0 | 0 | 3 |
| Insulin | 0 | 2 | 2 |
Drug classes tested here Corticosteroids 4 open · Angiogenesis inhibitors 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026A Single-Center Clinical Study to Evaluate the Efficacy and Safety of Autologous Urine-Derived Epithelial Cells in the Treatment of Corneal Endothelial Cell Dysfunction · Suxia Li
- Dec 2026Impact of GLP-1 Receptor Agonists on Dry Eye Disease in Patients With Type 2 Diabetes Mellitus and Obesity · Attikon Hospital
- Jan 2027A Single-Center Clinical Study to Evaluate the Efficacy and Safety of a Suture-Free Ophthalmic Hydrogel for Ocular Surface Tissue Adhesion · Suxia Li
- Feb 2027First in Human Study to Assess Safety and Efficacy of an Implantable Nitinol Device in the Treatment of Keratoconus · Recornea Srl
- Mar 2027Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy · University of Maryland, Baltimore
- May 2027Corneal Elastography and Patient Specific Modeling · The Cleveland Clinic
- May 2027Corneal Epithelial Thickness Mapping by Anterior Segment Optical Coherence Tomography in Patients With Refractive Errors · Sohag University
- Jun 2027Lacripep for Corneal Wound Healing Study · Henry M. Jackson Foundation for the Advancement of Military Medicine
- Jun 2027Characterization of the Corneal Biomechanics of Patients Treated by Corneal Lenticule Extraction for Advanced Refractive Correction (CLEAR) to Correct Myopia · University of Bern
- Jun 2027Accuracy of Corneal Astigmatism in Different Region Modes · Wenzhou Medical University
Who these studies take
Of the 33 Corneal Diseases studies recruiting now, 21 (64%) set no upper age limit and 5 (15%) stop at 75 or younger. 5 (15%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 8 (24%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (9%) | 3 (9%) |
| 18 | 26 (79%) | 26 (79%) |
| 30 | 33 (100%) | 33 (100%) |
| 40 | 32 (97%) | 32 (97%) |
| 50 | 32 (97%) | 32 (97%) |
| 65 | 30 (91%) | 30 (91%) |
| 75 | 29 (88%) | 29 (88%) |
| 85 | 25 (76%) | 25 (76%) |
Across all 219 studies, recruiting or not: 20% stop at 75 or younger and 15% at 65; 21% take children; 1% are for women only and 0% for men only; 36% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Corneal Diseases studies take
Of 43 interventional studies with no phase under Corneal Diseases, half reached primary completion within 22 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 22 mo5–45 · 43 studies | — | 23 mo5–54 · 37 studies |
| Observational | 16 mo12–76 · 25 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Stopped1
- Effects of Topical Insulin on Corneal Epithelium Healing After Corneal Crosslinking in Patients With KeratoconusTerminatedNov 5, 2026NCT06601101
Studies
Recruiting first, then most recently updated. Showing 50 of 219. Browse all 219 → or search them.
- A Single-Center Clinical Study Evaluating the Efficacy and Safety of Allogeneic Natural Killer (NK) Cell Transplantation for Mooren's UlcerNot yet recruitingNCT07782138Not applicable
- 4D Duke Microscope Integrated Optical Coherence Tomography in a Zeiss Artevo 800RecruitingNCT07024719Not applicable1 country
- OCT Vibrography for Biomechanical Properties of TissuesRecruitingNCT05759780Not applicable1 country
- Factors Influencing Corneal Donation in Palliative Care UnitRecruitingNCT078681981 country
- A Single-Center Clinical Study to Evaluate the Efficacy and Safety of a Suture-Free Ophthalmic Hydrogel for Ocular Surface Tissue AdhesionRecruitingNCT07608367Not applicable1 country
- Lacripep for Corneal Wound Healing StudyRecruitingNCT06854393Phase 21 country
- A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and DiseasesRecruitingNCT077808901 country
- Accuracy of Corneal Astigmatism in Different Region ModesRecruitingNCT032995301 country
- Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin MicroscopyRecruitingNCT069935971 country
- Clinical Predictors of Visual Outcome in Patients Affected With Ocular Surface DiseasesNot yet recruitingNCT076948171 country
- A Single-Center Clinical Study to Evaluate the Efficacy and Safety of Autologous Urine-Derived Epithelial Cells in the Treatment of Corneal Endothelial Cell DysfunctionRecruitingNCT07435142Not applicable1 country
- Prognosis of Posterior Lamellar KeratoplastyRecruitingNCT068594111 country
- Corneal Epithelial Thickness Mapping by Anterior Segment Optical Coherence Tomography in Patients With Refractive ErrorsNot yet recruitingNCT076471461 country
- Corneal Elastography and Patient Specific ModelingRecruitingNCT030307551 country
- Impact of GLP-1 Receptor Agonists on Dry Eye Disease in Patients With Type 2 Diabetes Mellitus and ObesityRecruitingNCT076055721 country
- Evaluation of the Clinical Efficacy and Mechanisms of Cord Plasma Eye Drops in the Treatment of Neuropathic Corneal PainRecruitingNCT07566806Not applicable1 country
- The Role of Transscleral Cyclophotocoagulation in Patients Undergoing a Boston KeratoprosthesisRecruitingNCT04232982Not applicable1 country
- Intacs Prescription Inserts for Keratoconus PatientsRecruitingNCT02138669Not applicable1 country
- Intraoperative Optical Coherence Tomography for Ophthalmic Surgical Guidance - CorneaNot yet recruitingNCT052104781 country
- Data Gathering for A10900RecruitingNCT071497401 country
- Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down SyndromeRecruitingNCT07135167Phase 31 country
- First in Human Study to Assess Safety and Efficacy of an Implantable Nitinol Device in the Treatment of KeratoconusRecruitingNCT06451718Not applicable2 countries
- Conjunctival Transpositional Surgery for Primary PterygiumRecruitingNCT07343011Not applicable1 country
- fMRI and IVCM Cornea Microscopy of CXL in KeratoconusRecruitingNCT044395521 country
- The OPTIMISE StudyRecruitingNCT05716945Phase 41 country
- Characterization of the Corneal Biomechanics of Patients Treated by Corneal Lenticule Extraction for Advanced Refractive Correction (CLEAR) to Correct MyopiaNot yet recruitingNCT048175921 country
- Topical Menthol For Tear SecretionEnrolling by invitationNCT07109609Phase 21 country
- AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)Enrolling by invitationNCT070962321 country
- Validation of the Use of Terahertz Scanning System on Corneal Scars and Corneal EdemaRecruitingNCT069836521 country
- Evaluation of the Safety of Terahertz Scanning System on CorneasRecruitingNCT069677921 country
- INTACS for Non Ectatic With High CylinderRecruitingNCT06963099Not applicable1 country
- The Relation Between BSS Solution Temperature and Endothelial Cells and Post Phaco DiscomfortNot yet recruitingNCT06904560Not applicable
- Artificial Intelligence for Screening of Multiple Corneal DiseasesRecruitingNCT062112181 country
- Inflammatory Biomarkers in Ocular Surface in Primary Open Angle Glaucoma or Ocular Hypertension Under Topical ProstaglandinsRecruitingNCT050396841 country
- Pretreatment to Promote Graft Survival After Subsequent High-risk Corneal Transplantation [CrossCornealVision]RecruitingNCT05870566Not applicable1 country
- Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial KeratitisRecruitingNCT06451172Early Phase 11 country
- Efficacy of 20% Autologous Serum Drops in the Treatment of Corneal Epitheliopathy Associated With Antihypertensive Glaucoma Drops.Not yet recruitingNCT06294015Phase 4
- Influence of Pupillary Behavior During Eye Surgery on Morphological and Functional OutcomeRecruitingNCT061609601 country
- A Study to Investigate the Safety and Clinical Activity of Belantamab Mafodotin in Combination With Daratumumab, Lenalidomide and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Transplant IneligibleRecruitingNCT05280275Phase 1/21 country
- A Study to Investigate Safety and Clinical Activity of Belantamab Mafodotin in Combination With Lenalidomide, Dexamethasone and Nirogacestat in Patients With Transplant Ineligible Newly Diagnosed Multiple MyelomaRecruitingNCT05573802Phase 1/21 country
- Dresden Corneal Disease and Treatment StudyRecruitingNCT042511431 country
- Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Riboflavin/Dextran or Riboflavin/MethylcelluloseRecruitingNCT04897503Phase 31 country
- A Study to Investigate the Safety and Clinical Activity of Belantamab Mafodotin in Combination With Daratumumab, Pomalidomide and Dexamethasone in Patients With Relapsed/ Refractory Multiple Myeloma Previously Treated With One Line Therapy Who Are Lenalidomide RefractoryNot yet recruitingNCT05581875Phase 1/2
- Euclid Phoenix Lens Design TrialCompletedNCT06389916Not applicable1 country
- Euclid Phoenix Lens Design Trial 2CompletedNCT06392607Not applicable1 country
- Effects of Topical Insulin on Corneal Epithelium Healing After Corneal Crosslinking in Patients With KeratoconusTerminatedNCT06601101Phase 31 country
- Acute Ocular Effects of Cigarette SmokingCompletedNCT075800401 country
- Safety of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface DiseaseCompletedNCT05204329Early Phase 11 country
- Insulin Eye Drops and Epithelial Healing After Corneal Cross-linkingCompletedNCT07812129Phase 2/31 country
- Corneal Topography and High Order Aberrations in Regular Contraceptive PillsCompletedNCT076936731 country