An observational study in Cornea and Refraction Error, sponsored by Elshimaa A.Mateen. Completed at 1 site in Egypt. Open to female participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-07-09.
Sponsored by Elshimaa A.Mateen · Observational
Effect of regular usage of contraceptive pills on corneal topography and corneal high-order aberrations
Comparing corneal topographic changes and corneal high-order aberrations for women planning to use oral contaceptive pills before and after the usage of the pills
130 studies on the registry are indexed under Corneal Diseases; 43 are open to participants now.
This study's enrollment of 40 is below the median of 102 across 46 observational studies indexed under Corneal Diseases.
Browse Corneal Diseases studies →Elshimaa A.Mateen is the lead sponsor of 2 studies on the registry; 1 is open to participants now.
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Premenopausal women aged 18-40 years attending the Ophthalmology Department at Sohag University Hospital who are prescribed combined oral contraceptive pills by their gynecologist as part of routine clinical care. Participants will undergo corneal topography and tomography before starting treatment and after 1 year of oral contraceptive use.
Exclusion Criteria:
Other: Hormonal Contraception · Drug: Combined Oral Contraceptive (COC)
Effect of usage of hormonal contraceptive pills on corneal topography and corneal high-order aberrations
Participants who are prescribed combined oral contraceptive pills as part of routine clinical care will be observed. Corneal topography and tomography will be performed before starting treatment and after the follow-up period to evaluate changes in corneal parameters.
Change in K1 (D)
Time frame: Baseline and 1 year
Change in K2 (D)
Time frame: one year
Change in Kmax (D)
Time frame: one year
change in corneal thickness (um)
Time frame: one year
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.
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Elshimaa A.Mateen