DrugSupplement
Riboflavin clinical trials
Also written Vitamin B2.
- studies test it
- 49
- open now
- 6
- in phase 3
- 17
- first study started
- 2005
Keep track of what changes. Save the Riboflavin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
Studies by the year they started
48 studies that test it; most in 2010 (7)
| Year | Studies |
|---|---|
| 2005 | 1 |
| 2008 | 2 |
| 2009 | 2 |
| 2010 | 7 |
| 2011 | 3 |
| 2012 | 5 |
| 2013 | 3 |
| 2014 | 4 |
| 2016 | 4 |
| 2017 | 2 |
| 2018 | 3 |
| 2019 | 1 |
| 2020 | 1 |
| 2021 | 5 |
| 2022 | 2 |
| 2023 | 2 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 3
- Phase 1
- 5
- Phase 2
- 16
- Phase 3
- 17
- Phase 4
- 2
- No phase
- 13
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 15 · Other 34
Cornea and Laser Eye Institute (6) · Glaukos Corporation (5) · University of Ulster (4) · Price Vision Group (4) · DSM Nutritional Products, Inc. (2) · Stephen Trokel (2) · University of Virginia (2) · University of Missouri-Columbia (2)
Often tested with
Tested in the same studies.
Levomefolic acid (2) · Dextrans (2) · Folic Acid (2) · Thiamine (2) · Ascorbic Acid (1) · Vitamin A (1) · Cholecalciferol (1) · Vitamin E (1)
Studies
Open first, then newest update. How each study uses Riboflavin is read from its arms, and is right about nine times in ten.
Testing it · 49
- Corneal Crosslinking for Treatment of Progressive Keratoconus or Corneal EctasiaRecruitingPhase 2/3Price Vision GroupNCT07841470Written as Riboflavin 0.1% ophthalmic solution and pulsed light
- Pack Cross Linking for Infectious KeratitisNot yet recruitingNot applicableSohag UniversityNCT05881187Written as Riboflavin
- Accelerated Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Pulse or Continuous UV-A LightRecruitingPhase 3Cornea and Laser Eye InstituteNCT05027295Written as riboflavin ophthalmic solution
- Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Riboflavin/Dextran or Riboflavin/MethylcelluloseRecruitingPhase 3Cornea and Laser Eye InstituteNCT04897503Written as Riboflavin
- Transepithelial (Epi-on) Corneal Collagen Crosslinking to Treat Keratoconus and Corneal EctasiaRecruitingPhase 3Cornea and Laser Eye InstituteNCT04905108Written as Riboflavin
- Treating Corneal Thinning Conditions With CCL Vario Riboflavin (CXL)Not yet recruitingEarly Phase 1Kent Wellish MDNCT04731727Written as Riboflavin
- Comparison of Standard vs. Accelerated Corneal CrosslinkingCompletedPhase 2/3Price Vision GroupNCT03922542Written as riboflavin 0.1%
- Evaluation of Progression of Myopia in Children Treated With Vitamin B2 and Outdoor Sunlight ExposureWithdrawnPhase 2University of Missouri-ColumbiaNCT03552016Written as Oral Riboflavin
- Dietary Riboflavin (Vitamin B-2) and Cornea Cross-LinkingTerminatedNot applicableUniversity of Missouri-ColumbiaNCT03095235Written as Dietary riboflavin
- Optimal Nutrition for Prevention of Hypertension in PregnancyActive, not recruitingNot applicableUniversity of UlsterNCT04723836Written as Riboflavin (5mg)
- Effects of Riboflavin in Mitigating Muscle Soreness in Ultra-marathon AthletesCompletedEarly Phase 1Steven MooreNCT05907850Written as Riboflavin
- Effect of Colon Delivered Vitamin B2 on Gut Microbiota and Related Health Biomarkers in Healthy Older AdultsCompletedNot applicableDSM Nutritional Products, Inc.NCT05803811Written as Riboflavin
- Safety and Effectiveness of the UV-X System for Corneal Collagen Cross-Linking in Eyes With Refractory Corneal InfectionCompletedPhase 1Stephen TrokelNCT02068430Written as Riboflavin 0.1%
- Higher Irradiance in Keratoconus EctasiaWithdrawnNot applicableStephen TrokelNCT01789333Written as Riboflavin 0.1% ophthalmic solution
- Corneal Collagen Crosslinking and Intacs for Keratoconus and EctasiaActive, not recruitingPhase 3Cornea and Laser Eye InstituteNCT01112072Written as Riboflavin
- Transepithelial Corneal Collagen Crosslinking for Keratoconus and Corneal EctasiaActive, not recruitingPhase 3Cornea and Laser Eye InstituteNCT01464268Written as Riboflavin
- Corneal Collagen Crosslinking for Progressive Keratoconus and Ectasia Using Riboflavin/Dextran and Hypotonic RiboflavinActive, not recruitingPhase 3Cornea and Laser Eye InstituteNCT01152541Written as Riboflavin/Dextran
- Intervention With Riboflavin to Improve Vascular Health and ENdothelial Functioning in Genetically at- Risk AdultsStatus unknownNot applicableUniversity of UlsterNCT05488106Written as Riboflavin 1.6mg/d
- The Effect of Riboflavin on Moderate to Severe Plaque Type PsoriasisCompletedPhase 2University of MichiganNCT02622386Written as Riboflavin
- Safety and Effectiveness Study of the VEGA UV-A System for Cross-linking in Eyes With Keratoconus and EctasiaTerminatedPhase 3Topcon Medical Systems, Inc.NCT01398852Written as Riboflavin
See all 49 studies that test Riboflavin →
Given in every arm · 13 — Riboflavin is usual care beside what is tested
- Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis UnitCompletedPhase 1/2Joseph B. Ciolino, MDNCT02863809Written as Riboflavin
- Safety Study of the VEGA UV-A System to Treat KeratoconusTerminatedPhase 3Topcon Medical Systems, Inc.NCT01190306Written as Riboflavin
- Safety Study of the VEGA UV-A System to Treat EctasiaTerminatedPhase 3Topcon Medical Systems, Inc.NCT01398839Written as Riboflavin
- Corneal Collagen Cross-linking for Progressive KeratoconusCompletedPhase 3Glaukos CorporationNCT00647699Written as riboflavin ophthalmic solution
- Corneal Collagen Cross-Linking for Ectasia (CXL)CompletedPhase 3Glaukos CorporationNCT00674661Written as riboflavin ophthalmic solution
- Ramelteon in the Prevention of Post-operative DeliriumCompletedPhase 2Johns Hopkins UniversityNCT02324153Written as Riboflavin 100 mg
- Smart Capsule for Automatic Adherence MonitoringCompletedNot applicableMedical University of South CarolinaNCT02344238Written as Riboflavin
- Microwave Treatment and Corneal Collagen Crosslinking for KeratoconusCompletedPhase 3Cornea and Laser Eye InstituteNCT01672814Written as riboflavin ophthalmic solution
- Safety & Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus or Corneal Ectasia After Refractive SurgeryTerminatedPhase 3American-European Congress of Ophthalmic SurgeryNCT01459679Written as riboflavin ophthalmic solution
- Treatment of Keratoconus With Advanced CXL-IIStatus unknownPhase 2Umeå UniversityNCT02514200Written as Riboflavin
- Clinical and Structural Outcome of Conventional Versus Accelerated Corneal Collagen Cross-linking (CXL).Status unknownPhase 1/2Oslo University HospitalNCT02883478Written as riboflavin with hydroxypropyl methylcellulose
- Study of the Safety and Effectiveness of Collagen Cross-Linking at an Irradiance of 9 mW/cm2 and 18 mW/cm2Status unknownPhase 1Robert Mack, M.D.NCT02009709Written as Riboflavin 0.1% ophthalmic solution
- Adapted Fluence Settings for Corneal Collagen Cross-linking in Mild to Moderate Progressive KeratoconusStatus unknownPhase 1/2Tehran University of Medical SciencesNCT02507362Written as riboflavin 0.1% combined with dextran 20 %
As the comparator · 1 — what is tested is compared with Riboflavin
Codes
What other systems call Riboflavin · ClinicalTrials.gg INT008161
- MeSH (NLM) D012256RiboflavinConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) TLM2976OFRRIBOFLAVINConfirmed FDA, NLM, Wikidata
- RxNorm 9346Confirmed FDA, Wikidata
- Wikidata Q130365riboflavinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C808RiboflavinOne source FDA
- DrugBank DB00140One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D012256 | Riboflavin | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | TLM2976OFR | RIBOFLAVIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 9346 | — | Confirmed FDA, Wikidata |
| Wikidata | Q130365 | riboflavin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C808 | Riboflavin | One source FDA |
| DrugBank | DB00140 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.