Fuchs' Endothelial Dystrophy clinical trials
The registry lists 90 studies for Fuchs' Endothelial Dystrophy across more than 10 countries. 28 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-14.
Status
- Completed
- 44
- Recruiting
- 22
- Status unknown
- 10
- Not yet recruiting
- 4
- Terminated
- 4
- Withdrawn
- 3
Phase
- Phase 2
- 16
- Phase 3
- 8
- Phase 1
- 7
- Phase 4
- 5
- Early Phase 1
- 3
Where
- United States
- 41
- Germany
- 12
- France
- 11
- Spain
- 7
- Denmark
- 7
- Netherlands
- 5
Who runs them
Cornea Research Foundation of America (5) · Centre Hospitalier Universitaire de Saint Etienne (5) · Massachusetts Eye and Ear Infirmary (4) · Kowa Research Institute, Inc. (3) · Price Vision Group (3) · Maastricht University Medical Center (3) · Oregon Health and Science University (2) · Singapore Eye Research Institute (2)
Studies
Recruiting first, then most recently updated. Showing 50 of 90 — search for more.
- The Effect of Topical Rho-kinase Inhibitors on Corneas of Patients With Fuchs Endothelial Corneal DystrophyEnrolling by invitationNCT069695861 country
- Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal DystrophyRecruitingNCT04440280Phase 21 country
- Partial Range Of Field IOLs in DMEK-Enabled ProceduresNot yet recruitingNCT07441616Not applicable1 country
- Descemet Endothelial Thickness Comparison Trial IIRecruitingNCT05275972Phase 31 country
- Postoperative CCT in FECD vs. Non-FECDNot yet recruitingNCT07731945
- Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial DysfunctionNot yet recruitingNCT07729137Phase 21 country
- Prognosis of Posterior Lamellar KeratoplastyRecruitingNCT068594111 country
- Effect of Descemet Membrane Polishing in Fuchs Endothelial Corneal DystrophyRecruitingNCT07539012Not applicable1 country
- Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in FranceRecruitingNCT057423211 country
- Plasma Rich in Growth Factors in Corneal Endothelial TransplantationRecruitingNCT06261346Not applicable1 country
- Effect of Donor Diabetes and Other Factors on Corneal Transplant Endothelial Cell Loss and Success at 5 YearsEnrolling by invitationNCT07217249Not applicable1 country
- Influence of Supine Positioning on the Outcomes After Descemet Membrane Endothelial Keratoplasty (DMEK)RecruitingNCT07373821Not applicable1 country
- PVEK Corneal Implant For Treatment of Corneal EdemaRecruitingNCT07325097Phase 12 countries
- DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal DystrophyRecruitingNCT07024693Phase 21 country
- Study to Assess Safety and Tolerability of Multiple Doses of EO2002RecruitingNCT05636579Phase 11 country
- SUCCESS Score Validation in Fuchs DystrophyRecruitingNCT072653881 country
- A Study to Test the Diagnostic Potential of Brillouin Microscopy for Corneal EctasiaRecruitingNCT021189221 country
- The OPTIMISE StudyRecruitingNCT05716945Phase 41 country
- Safety and Efficacy of Tissue Engineered Endothelial KeratoplastyRecruitingNCT04319848Phase 11 country
- OCT in Fuchs' DystrophyRecruitingNCT042587871 country
- Comparison of Outcomes Between Femtosecond Laser-Assisted and Conventional Phacoemulsification in Fuchs Endothelial Corneal Dystrophy Patients With CataractsRecruitingNCT069661671 country
- Brillouin Microscopy Used to Evaluate Corneal Mechanical PropertiesNot yet recruitingNCT06914817Not applicable1 country
- FECD-TRACE: Fuchs' Endothelial Corneal Dystrophy TRAjectory and Correlation With Genotype in the United KingdomRecruitingNCT068817711 country
- Trial Comparing Cataract Surgery with Triple-DMEK in Patients with Cataract and Fuchs Endothelial Corneal DystrophyRecruitingNCT06425666Not applicable4 countries
- The Effects of Ripasudil in Patients with FED Undergoing Femtosecond Laser Assisted Cataract SurgeryRecruitingNCT06048380Phase 31 country
- Endothelial Side Up Inverted Femtosecond Laser Assisted DSAEKRecruitingNCT06652321Not applicable1 country
- Ripasudil for Enhanced Corneal Clearing Following Descemet Membrane Endothelial Keratoplasty in Fuchs' DystrophyRecruitingNCT03813056Phase 21 country
- Glanatec(R) for Descemet Stripping in Fuch's Endothelial DystrophyRecruitingNCT03249337Phase 41 country
- The Belgian Endothelial Surgical Transplant of the CorneaActive, not recruitingNCT05436665Not applicable1 country
- A Multicenter Study Assessing the Efficacy and Safety of STN1010904 Ophthalmic Suspension 0.03% and 0.1% Compared With Vehicle in Subjects With Fuchs Endothelial Corneal Dystrophy (FECD)CompletedNCT05376176Phase 23 countries
- DISCOVER Study: Microscope-integrated Intraoperative OCT StudyCompletedNCT024232131 country
- A Study to Evaluate the Safety and Efficacy of K-321 Eye Drops After Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)CompletedNCT05795699Phase 36 countries
- A Comparison of Visual Functions and Side-effects After DSAEK or DMEK for Fuchs' Endothelial DystrophyCompletedNCT04417959Not applicable1 country
- Impact of Donor Diabetes on DMEK Success and Endothelial Cell LossCompletedNCT05134480Not applicable1 country
- Assessment of Corneal Endothelial Function Following Hypoxic StressWithdrawnNCT04175938Phase 1/21 country
- A Study to Investigate the Safety and Efficacy of K-321 Eye Drops After Simultaneous Cataract Surgery and Descemetorhexis in Participants With Fuchs Endothelial Corneal Dystrophy (FECD)CompletedNCT05826353Phase 36 countries
- Prevalence of Fuchs Endothelial Corneal Dystrophy in a Population of Dermatology Patients.CompletedNCT071170711 country
- The Evaluation of Balanced Salt Solution During Cataract SurgeryCompletedNCT05853978Phase 41 country
- Study of Safety and Tolerability of EO2002 in the Treatment of Corneal EdemaCompletedNCT04894110Phase 11 country
- Study to Investigate the Safety and Efficacy of K-321 in Patients With Fuchs Endothelial Corneal Dystrophy (FECD) Following DescemetorhexisCompletedNCT04250207Phase 25 countries
- Association Between Fuchs' Endothelial Corneal Dystrophy Severity and Estrogen ExposureCompletedNCT045643781 country
- PIONEER: Intraoperative and Perioperative OCT StudyCompletedNCT024231611 country
- Novel Diagnostics With Optical Coherence Tomography: Imaging the Anterior EyeCompletedNCT003434731 country
- Netarsudil Use After Descemtorhexis Without Endothelial KeratoplastyCompletedNCT04752020Early Phase 11 country
- TTHX1114(NM141) in Combination With DWEK/DSOCompletedNCT04676737Phase 21 country
- A Phase 1/ Phase 2 Study of TTHX1114(NM141)CompletedNCT04520321Phase 1/21 country
- Supine Positioning for Graft Attachment After Descemet Membrane Endothelial KeratoplastyCompletedNCT05399095Not applicable1 country
- Analysis of the Genotype/Phenotype Relationship in the Fuchs' Corneal Endothelial Dystrophy in France.CompletedNCT039742301 country
- Trial of Netarsudil for Acceleration of Corneal Endothelial RestorationTerminatedNCT03971357Phase 2/31 country
- Descemet Membrane Endothelial Keratoplasty vs. Descemet's Stripping With Endothelial Keratoplasty vs. Descemet Stripping OnlyTerminatedNCT045275231 country