Corneal Opacity clinical trials
The registry lists 37 studies for Corneal Opacity across more than 10 countries. 5 are recruiting or about to start. 16 of them are mainly about Corneal Opacity (how this is decided). Per ClinicalTrials.gov, last updated 2026-07-16.
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Who runs them
Oregon Health and Science University (6) · The S.N. Fyodorov Eye Microsurgery State Institution (2) · Assiut University (2) · CorNeat Vision Ltd. (2) · Massachusetts Eye and Ear Infirmary (1) · The Filatov Institute of Eye Diseases and Tissue Therapy (1) · University of California, Irvine (1) · University of Utah (1)
What is being tested here
Drugs under test in Corneal Opacity studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Dec 2026Optical Coherence Tomography Guided Transepithelial Phototherapeutic Keratectomy · Oregon Health and Science University
- Dec 2026Clinical Outcomes of the Gore Synthetic Cornea Device · W.L.Gore & Associates
- Feb 2027Losartan for Corneal Fibrosis · Universidad Autonoma de Nuevo Leon
Who these studies take
Of the 5 Corneal Opacity studies recruiting now, 3 (60%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (20%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 5 (100%) | 5 (100%) |
| 75 | 5 (100%) | 5 (100%) |
| 85 | 5 (100%) | 5 (100%) |
Across all 37 studies, recruiting or not: 32% stop at 75 or younger and 24% at 65; 22% take children; 3% are for women only and 0% for men only; 22% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 37 of 37. search them.
- Losartan for Corneal FibrosisRecruitingNCT07449000Not applicable1 country
- PRoTECT: Corneal Wavefront Guided PRK + Epi-off CXL vs. PTK+Epi-off CXL in KeratoconusRecruitingNCT07372911Not applicable1 country
- OCT in Diagnosis of Irregular CorneasRecruitingNCT035048001 country
- Optical Coherence Tomography Guided Transepithelial Phototherapeutic KeratectomyRecruitingNCT01243931Not applicable1 country
- Observational Study of Corneal Opacities in AdultsRecruitingNCT021094711 country
- Clinical Outcomes of the Gore Synthetic Cornea DeviceActive, not recruitingNCT06174376Not applicable1 country
- Study to Evaluate the Clinical Safety and Performance of the CorNeat KPro for Treatment of Corneal BlindnessTerminatedNCT05694247Not applicable4 countries
- The Natural History of Mucolipidosis Type IVTerminatedNCT010677421 country
- Photorefractive Keratectomy (PRK) : Comparison of Corneal Haze Between Two Modes of De-epithelialisation (Laser Versus Manual Alcohol)TerminatedNCT05072977Not applicable1 country
- Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) GraftCompletedNCT02592330Phase 1/21 country
- First in Human (FIH) Study to Assess Safety and Efficacy of the CorNeat KPro for the Treatment of Corneal BlindnessTerminatedNCT04485858Not applicable5 countries
- Pathogenetic Risk Factors for Corneal Graft RejectionCompletedNCT062815871 country
- Characteristics of Trachomatous Corneal Opacity in Fayoum University HospitalCompletedNCT060001501 country
- Refractive Transepithelial Photo-keratectomy (T-PKR) in High MyopiaCompletedNCT049175621 country
- Evaluation Of Deep Anterior Lamellar Keratoplasty By Anterior Segment Ocular Coherence TomographyStatus unknownNCT05345652
- The Use of MMC During PRK and Its Effect on Postoperative Topical Steroid RequirementsStatus unknownNCT02030990Phase 2/31 country
- Correlation of Scheimpflug Densitometry Measurements of Corneal Haze With Disability GlareWithdrawnNCT022448921 country
- Effect of Ectoine After Photorefractive Keratectomy (PRK).Status unknownNCT053134251 country
- Phacoemulsification in Patients With Corneal OpacitiesCompletedNCT05014269
- Loteprednol vs. Prednisolone and FluorometholoneCompletedNCT03123614Phase 41 country
- Efficacy of an Ocular Bandage Contact Lens for the Treatment of Dry Eye After Complicated and Combined Cataract SurgeryStatus unknownNCT04120389Not applicable1 country
- The Effect of Thyroid Hormon Levels on the Corneal MeasuresCompletedNCT047529691 country
- SINGLE PATIENT EXPANDED ACCESS OF A PROSPECTIVE, MULTICENTER CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND PROBABLE BENEFIT OF THE KERAKLEAR NON-PENETRATING KERATOPROSTHESIS IN SUBJECTS WITH CORNEAL OPACITY WITH POOR PROGNOSIS FOR CORNEAL TRANSPLANTWithdrawnNCT03812341Not applicable1 country
- OCT-guided LALAK for KCNTerminatedNCT01901614Not applicable1 country
- Safety and Effectiveness of Collagen-phosphorylcholine Bioengineered Cornea in Patients Requiring Lamellar KeratoplastyCompletedNCT02277054Not applicable1 country
- Safety and Effectiveness of the RHCIII-MPC Biosynthetic Cornea in Patients Requiring Anterior Lamellar KeratoplastyCompletedNCT02424006Not applicable1 country
- OCT-guided LALAK in ChildrenTerminatedNCT01579643Not applicable1 country
- Corneal Opacities in ChildrenCompletedNCT021173231 country
- Implantable Intraocular Pressure Sensor for Glaucoma Monitoring in Patients With Boston Keratoprosthesis Type 1WithdrawnNCT03421548Not applicable
- Topical Anesthesia for Closed PKP vs Retrobulbar Anesthesia for Open-sky PKPStatus unknownNCT02826174Not applicable1 country
- Femtosecond Laser-assisted Anterior Lamellar KeratoplastyCompletedNCT02301598Not applicable
- Laser Assisted Procedures in Penetrating KeratoplastyCompletedNCT02173847Not applicable1 country
- Phototherapeutic Keratectomy (PTK) With Mitomycin in Adenoviral OpacitiesStatus unknownNCT00492245Not applicable1 country
- Evaluation Study for a Non-Contact BiometerCompletedNCT004943901 country
- Dynamic Light Scattering and Keratoscopy for Corneal ExaminationCompletedNCT000504661 country
- Comparison of Ultrasonic Pachymetry With Orbscan in Corneal HazeCompletedNCT004391141 country
- Comparison of Acular LS Versus Nevanac for Pain Control in Eyes Undergoing PRKCompletedNCT00347204Phase 4