Cardiomyopathies clinical trials
The registry lists 553 studies for Cardiomyopathies across more than 10 countries. 152 are recruiting or about to start. 196 of them are mainly about Cardiomyopathies (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its 8 narrower conditions too, such as Cardiomyopathy, Hypertrophic: 1,389 studies, 396 open.
ClinicalTrials.gov finds 1,903 studies for Cardiomyopathies. How that becomes 552 here
This page counts the studies the registry files under Cardiomyopathies, and those it files under no condition that list Cardiomyopathiesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 1,903Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −816Filed under a narrower condition, counted on its own pageCardiomyopathy, Hypertrophic 323 · Cardiomyopathy, Dilated 179 · Myocarditis 119 · Myocardial Reperfusion Injury 56 · Takotsubo Cardiomyopathy 53 · Diabetic Cardiomyopathies 27 · 2 more
- −307List Cardiomyopathies as a condition, but the registry did not file them under itMost often written as “Ischemic Cardiomyopathy” (89), “Non-ischemic Cardiomyopathy” (21), and “Transthyretin Amyloid Cardiomyopathy” (19). The registry filed 83 of them under no condition at all, and the others under other conditions only, most often Heart Failure (75) and Amyloid Neuropathies, Familial (30).
- −228Match it another way144 name it in the title, 51 in a keyword, and 33 by a synonym or other text the search reads.
- 552The count on this page
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Status
Who runs them
National Heart, Lung, and Blood Institute (NHLBI) (14) · Mayo Clinic (11) · Assistance Publique - Hôpitaux de Paris (10) · Alnylam Pharmaceuticals (9) · Emory University (8) · Abbott Medical Devices (8) · University Hospital, Bonn (6) · Lexeo Therapeutics (6)
What is being tested here
Drugs under test in Cardiomyopathies studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Acoramidis | 3 | 3 | 5 |
| Melatonin | 2 | 1 | 2 |
| Carvedilol | 1 | 0 | 4 |
| Vutrisiran | 1 | 2 | 2 |
| HRS-1893 | 1 | 0 | 2 |
| NTLA-2001 | 1 | 1 | 2 |
| Deferoxamine | 1 | 0 | 2 |
| Nicorandil | 1 | 0 | 1 |
| Selenium | 1 | 0 | 1 |
| MYK-461 | 1 | 0 | 1 |
Drug classes tested here Beta blockers 1 open · SGLT2 inhibitors 1 open · Mineralocorticoid receptor antagonists (MRAs) 4 · Corticosteroids 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Role of Spectral CT in the Diagnosis of Myocarditis/MINOCA in Patients Undergoing cardioCT Investigations for Acute Chest Pain · IRCCS Azienda Ospedaliero-Universitaria di Bologna
- Dec 2026Gene Therapy for ACM Due to a PKP2 Pathogenic Variant · Lexeo Therapeutics
- Dec 2026IVTCC 2.0: A Prospective Multicenter Ventricular Tachycardia Catheter Ablation Registry · University of California, Los Angeles
- Dec 2026AI-powered ECG Analysis Using Willem™ Software in High-risk Cardiac Patients (WILLEM) · Idoven 1903 S.L.
- Dec 2026PPG to Predict Ejection Fraction and Other Echographic Data in the General Population · Tulane University
- Dec 2026Quantitative Cardiac Parametric Mapping · Medical University of South Carolina
- Dec 2026Early Assessment of Cardiac Function After Treatment With CAR-T Cells · Assistance Publique - Hôpitaux de Paris
- Dec 2026Noninvasive Cardiovascular Diagnosis of Patients With Fully Magnetically Levitated Blood Pumps · Thomas Schlöglhofer, PhD, MSc
- Dec 2026Edema and Fibrosis CMR Imaging in Cardiomyopathy · University of Pennsylvania
- Dec 2026Observational Study to Validate a Family Physician Echocardiography Training Programme · Societat Catalana de Medicina Familiar i Comunitària, Assoc. (CAMFiC)
Who these studies take
Of the 116 Cardiomyopathies studies recruiting now, 71 (61%) set no upper age limit and 17 (15%) stop at 75 or younger. 36 (31%) take children under 18. 2 (2%) are for women only and 5 (4%) for men only; 22 (19%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 22 (19%) | 27 (23%) |
| 18 | 105 (91%) | 108 (93%) |
| 30 | 105 (91%) | 106 (91%) |
| 40 | 104 (90%) | 105 (91%) |
| 50 | 104 (90%) | 105 (91%) |
| 65 | 102 (88%) | 103 (89%) |
| 75 | 99 (85%) | 100 (86%) |
| 85 | 85 (73%) | 86 (74%) |
Across all 553 studies, recruiting or not: 22% stop at 75 or younger and 16% at 65; 23% take children; 3% are for women only and 5% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Cardiomyopathies studies take
Of 20 phase 3 interventional studies under Cardiomyopathies, half reached primary completion within 57 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 39 mo26–58 · 16 studies | — | — |
| Phase 3 | 57 mo49–103 · 20 studies | — | — |
| Interventional, no phase | 39 mo23–52 · 51 studies | — | 35 mo21–53 · 40 studies |
| Observational | 83 mo34–… · 140 studies | — | 87 mo34–… · 119 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
- Olive Oil Supplementation for Heart Failure With Reduced Ejection FractionOct 16, 2026NCT07644806
Results posted2
- Open-Label Study of AG10 in Patients With CardiomyopathyOct 14, 2026NCT03536767
- AI-SCREENDCM Decentralized Clinical Trial - Pilot StudyOct 13, 2026NCT06609174
Stopped1
- Open-Label Study of AG10 in Patients With CardiomyopathyTerminatedOct 14, 2026NCT03536767
Newly registered3
- Focal Pulsed Field Ablation of Ventricular TachycardiaNov 10, 2026NCT07929545
- 31P-MRS Myocardial Energetic Phenotyping and Prognosis Across the Cardiac Disease SpectrumNov 3, 2026NCT07912086
- The Impact of Using Nicorandil for the Prevention of Doxorubicin-Induced CardiotoxicityOct 27, 2026NCT07897409
Studies
Recruiting first, then most recently updated. Showing 50 of 553. Browse all 553 → or search them.
- Focal Pulsed Field Ablation of Ventricular TachycardiaEnrolling by invitationNCT079295451 country
- AI-powered ECG Analysis Using Willem™ Software in High-risk Cardiac Patients (WILLEM)RecruitingNCT058907162 countries
- Essen Amyloidosis RegistryRecruitingNCT068872831 country
- MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)RecruitingNCT06128629Phase 326 countries
- Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular SystemRecruitingNCT011434541 country
- A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping CatheterRecruitingNCT07116525Not applicable3 countries
- Positron Emission Tomography to Assess the Effect of Camzyos on Ischaemia in HOCM: PEACH TrialRecruitingNCT07120776Not applicable1 country
- PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility StudyNot yet recruitingNCT053773201 country
- 31P-MRS Myocardial Energetic Phenotyping and Prognosis Across the Cardiac Disease SpectrumRecruitingNCT079120861 country
- Genetic Markers of Cardiovascular Disease in EpilepsyRecruitingNCT028248221 country
- The Impact of Using Nicorandil for the Prevention of Doxorubicin-Induced CardiotoxicityNot yet recruitingNCT07897409Phase 21 country
- PET/CT Imaging in Carriers of TTR MutationsNot yet recruitingNCT075910381 country
- A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With CardiomyopathyEnrolling by invitationNCT06679946Phase 317 countries
- TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With CardiomyopathyRecruitingNCT07052903Phase 336 countries
- The Multicenter Cardiology Monitoring Platform RegistryRecruitingNCT049763481 country
- Danon Disease Natural History StudyRecruitingNCT062145077 countries
- BAG3-DCM Natural History StudyNot yet recruitingNCT07486752
- Clinical Course Of Disease In Participants With FA-CMRecruitingNCT068654828 countries
- Olive Oil Supplementation for Heart Failure With Reduced Ejection FractionRecruitingNCT07644806Not applicable1 country
- Non-Invasive Method for Evaluation of Cardiac Resynchronization TherapyRecruitingNCT058686161 country
- PKP2-ACM Natural History StudyRecruitingNCT066447422 countries
- Optimal PharmacoTherapy and Invasive Management of Atrial Fibrillation in Patients With Heart FailureNot yet recruitingNCT07238452Phase 3
- Hypertrophic Cardiomyopathy Registry, Biobank and Imaging Data RepositoryRecruitingNCT051004201 country
- DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World SettingRecruitingNCT073580783 countries
- A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ATI-105 in Healthy AdultsNot yet recruitingNCT07869654Phase 11 country
- A Study to Learn About the Use of Acoramidis in Patients With a Heart Condition Called Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in a Real-world SettingRecruitingNCT0723546217 countries
- A Gene Therapy Study of RP-A501 in Male Patients With Danon DiseaseRecruitingNCT06092034Phase 24 countries
- Technical and Translational Development of Cardiovascular Magnetic Resonance (CMR) ImagingRecruitingNCT035813181 country
- Nutritional Assessment in Children With CardiomyopathyNot yet recruitingNCT07858474
- Patient Selection and Long-Term Outcomes of Pace & Ablate Strategy in Atrial FibrillationRecruitingNCT078522213 countries
- A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated CardiomyopathyRecruitingNCT07137338Phase 11 country
- Phase IA and IB Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's AtaxiaRecruitingNCT05302271Phase 11 country
- ATR 1072 in Participants With PRKAG2 SyndromeRecruitingNCT07738107Phase 1/21 country
- Genetic Characterization of Patients With Arrhythmia-Induced CardiomyopathyRecruitingNCT068962661 country
- JOint Use of Database to Identify Risk Factors of CARDio-vascular Toxicity Induced by Immune Checkpoint InhibitorsRecruitingNCT042947711 country
- Pacing Advancements With Cost and Experience VALuation for Unified Patient-Led Clinical Evidence - the PACEVALUE StudyRecruitingNCT072761397 countries
- RHYthm and Myocardial Function Relationship Evaluation in Heart DiseasesRecruitingNCT074912371 country
- Multimodal Physiologic State Intelligence StudyEnrolling by invitationNCT078141181 country
- Targeted Ablation to Isolate Scar Channels Causing Ventricular TachycardiaRecruitingNCT078140791 country
- Early Screening and Treatment of Heart Complication in Sickle Cell DiseaseRecruitingNCT07023666Phase 21 country
- Procedural Endpoint in Left Bundle Branch Area Pacing: Conduction System Capture Versus LV Septal CaptureNot yet recruitingNCT07804394Not applicable
- Study of LX2006 Gene Therapy in Friedreich Ataxia CardiomyopathyRecruitingNCT07721025Phase 21 country
- Validation of Myocardial Perfusion and Extracellular Volume Assessment Using Photon-Counting Computed Tomography (PCCT) Compared With Cardiac Magnetic Resonance (CMR) in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI)RecruitingNCT077993631 country
- Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne CardiomyopathyRecruitingNCT07172971Phase 11 country
- Impella Reverse Remodeling in End-Stage Heart FailureRecruitingNCT068007161 country
- Liver and Coagulation Disorders in Cardiac Transthyretin AmyloidosisRecruitingNCT077661351 country
- Performance of the Cardiac Microcurrent (C-MIC) System With a Less Invasively Placed Left Ventricular LeadRecruitingNCT06920030Not applicable2 countries
- To Evaluate the Long-term Safety and Tolerability of Acoramidis in Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE)Not yet recruitingNCT07116473Phase 3
- Cardiovascular Multimodality Imaging StudyRecruitingNCT066100191 country
- Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp SystemRecruitingNCT06080074Phase 21 country