Takotsubo Cardiomyopathy clinical trials
The registry lists 63 studies for Takotsubo Cardiomyopathy across more than 10 countries. 26 are recruiting or about to start. 48 of them are mainly about Takotsubo Cardiomyopathy (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13.
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Who runs them
University of Aberdeen (6) · University of Edinburgh (3) · Mayo Clinic (3) · Assistance Publique - Hôpitaux de Paris (3) · University of Zurich (3) · Sahlgrenska University Hospital (3) · Ospedale San Giovanni Bellinzona (2) · University of Campania Luigi Vanvitelli (2)
What is being tested here
Drugs under test in Takotsubo Cardiomyopathy studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Nov 2026Prognotic Role of CMR in Takotsubo Syndrome · University of Cagliari
- Feb 2027Cyclosporine In Takotsubo Syndrome · University Hospital Heidelberg
- Jun 2027Autonomic Modulation in Takotsubo Syndrome · NYU Langone Health
- Jun 2027Coronary and Cerebral Microvascular Dysfunction in Neurological Diseases · University Medicine Greifswald
- Aug 2027Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis Transition · University of Edinburgh
- Aug 2027EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases · Assistance Publique - Hôpitaux de Paris
Who these studies take
Of the 23 Takotsubo Cardiomyopathy studies recruiting now, 19 (83%) set no upper age limit and 0 (0%) stop at 75 or younger. 3 (13%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (13%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (13%) | 3 (13%) |
| 18 | 21 (91%) | 21 (91%) |
| 30 | 22 (96%) | 22 (96%) |
| 40 | 23 (100%) | 23 (100%) |
| 50 | 23 (100%) | 23 (100%) |
| 65 | 23 (100%) | 23 (100%) |
| 75 | 23 (100%) | 23 (100%) |
| 85 | 22 (96%) | 22 (96%) |
Across all 63 studies, recruiting or not: 5% stop at 75 or younger and 0% at 65; 10% take children; 6% are for women only and 0% for men only; 19% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Takotsubo Cardiomyopathy studies take
Of 25 observational studies under Takotsubo Cardiomyopathy, half reached primary completion within 50 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Observational | 50 mo40–… · 25 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 63. Browse all 63 → or search them.
- Inflammatory Disease Biobank for Immunophenotyping and Cardiovascular ResearchNot yet recruitingNCT07737470
- Manganese-enhanced Magnetic Resonance Imaging in Takotsubo CardiomyopathyRecruitingNCT07491718Not applicable1 country
- Cardiac Assessment and Takotsubo-stunning Among COPD-exacerbations In-HospitalRecruitingNCT065973311 country
- Establishing the Incidence of Tako-tsubo Cardiomyopathy in ScotlandRecruitingNCT032995691 country
- Cardiomyopathies and Heart Muscle Diseases: Cardiac Imaging in the Evaluation of Myocardial Fibrosis TransitionRecruitingNCT064095851 country
- The Cedars-Sinai Smidt Heart Institute Takotsubo Registry & Proteomic StudyRecruitingNCT039105691 country
- Effectiveness of a Resilience-Based Rehabilitation Program for Patients With Coronary Heart DiseaseRecruitingNCT06332859Not applicable1 country
- Psychosocial Support for Patients With Takotsubo SyndromeRecruitingNCT05977049Not applicable1 country
- EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular DiseasesRecruitingNCT070773041 country
- Cyclosporine In Takotsubo SyndromeRecruitingNCT05946772Phase 21 country
- Is There a Genetic Predisposition for Acute Stress-induced (Takotsubo) CardiomyopathyRecruitingNCT04513054Not applicable1 country
- Registry of Patients With Takotsubo SyndromeRecruitingNCT036633481 country
- The GErman Italian Spanish Takotsubo (GEIST) RegistryRecruitingNCT043619942 countries
- Coronary and Cerebral Microvascular Dysfunction in Neurological DiseasesNot yet recruitingNCT070099901 country
- Prognotic Role of CMR in Takotsubo SyndromeRecruitingNCT062772971 country
- Mechanisms And Prognosis of Stroke-Heart SyndromeRecruitingNCT069541031 country
- Internet-based Treatment of Stress and Anxiety in Myocardial Infarction With Non-obstructive Coronary ArteriesRecruitingNCT04178434Not applicable1 country
- BROKEN-SWEDEHEART- Optimized Pharmacological Treatment for Broken Heart (Takotsubo) Syndrome.RecruitingNCT04666454Phase 43 countries
- Characterisation of the Biochemical Profile and Physiology of the Coronary Circulation in Takotsubo SyndromeRecruitingNCT066699621 country
- Beta-Blockers in Takotsubo Syndrome StudyNot yet recruitingNCT06509074Phase 41 country
- Characterization of Acute Myocardial Damage With Spectral Computed Tomography. (CADAMI-SPECTRAL)RecruitingNCT065060711 country
- Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA and MINOCA-mimicsRecruitingNCT06323811Not applicable1 country
- Takotsubo Syndrome and Air PollutionRecruitingNCT057318301 country
- Characterization of priMary And sEcondary STress Related takOtsuboRecruitingNCT05793008Not applicable1 country
- Acute Cardiac Dysfunction in Critical IllnesRecruitingNCT058605041 country
- Polish Registry of Takotsubo SyndromeRecruitingNCT046344871 country
- The Role of CD34+ Stem Cells in the Pathogenesis of Takotsubo SyndromeActive, not recruitingNCT076044671 country
- The Broken Heart Study II (BHS-II)CompletedNCT04325321Not applicable1 country
- Autonomic Modulation in Takotsubo SyndromeActive, not recruitingNCT03324529Not applicable1 country
- Italian Multicenter Observational Registry on Takostubo SyndromeActive, not recruitingNCT06643949
- Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic, Inflammatory and Takotsubo Cardiomyopathy (MEMORY)CompletedNCT046237881 country
- Predicting the Development of Myocardial Depression in Acute Neurological PatientsCompletedNCT038016941 country
- Life-style Interventions for Modulating the Brain Phenotype of Takotsubo CardiomyopathyCompletedNCT05530135Not applicable1 country
- Physical Exercise and Mental Wellbeing Rehabilitation for Acute Stress-induced Takotsubo Cardiomyopathy: The PLEASE StudyCompletedNCT04425785Not applicable1 country
- Sympathetic and Vascular Function in Takotsubo SyndromeCompletedNCT05768542Phase 1/2
- Optimized Characterization of Takotsubo Syndrome by Obtaining Pressure Volume LoopsCompletedNCT03726528Not applicable1 country
- Takotsubo Cardiomyopathy in Patients Suffering From Acute Non-traumatic Subarachnoid HemorrhageCompletedNCT026598781 country
- Long-term Echocardiographic Findings in Takotsubo SyndromeStatus unknownNCT05084157
- Detection of Myocardial Dysfunction in Non-severe Subarachnoid Hemorrhage (WFNS 1-2) Using Speckle-tracking Echocardiography (STRAIN)CompletedNCT037616541 country
- The Role of Sympathetic Tone Regarding the Anatomical and Functional Recovery of the Left Ventricle in TakoTsubo SyndromeStatus unknownNCT046955871 country
- Hyperglycemia in Patients With Takotsubo SyndromeCompletedNCT046840041 country
- Left Ventricular Dysfunction in Critically Ill PatientsCompletedNCT037878101 country
- Psyhosomatic Medicine in Oncologic and Cardiac Disease StudyStatus unknownNCT034376421 country
- French Observatory Syndromes Tako-TsuboCompletedNCT012520041 country
- Persistent Symptoms and Early Incomplete Recovery After Acute Stress-induced Cardiomyopathy: Is There Ongoing Heart Distress? The HEROIC StudyCompletedNCT029894541 country
- Pathogenesis of Acute Stress Induced (Tako-tsubo) Cardiomyopathy: Energy Shut-Down or Intense Inflammation?CompletedNCT028977391 country
- Brain fMRT In Takotsubo CardiomyopathyCompletedNCT022400561 country
- Adenosin to Rapidly Reverse Left Ventricle Impairment in Takotsubo SyndromeTerminatedNCT02867878Phase 21 country
- Mindfulness-based Sex Therapy on Patients With Takotsubo CardiomyopathyStatus unknownNCT03372577Not applicable1 country
- Brain-heart Interactions in Tako-Tsubo Cardiomyopathy and Cardiac Syndrome X:CompletedNCT02759341Not applicable1 country